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1. 发明申请

WO2011035006A3 A SYMMETRICAL DRIVE SYSTEM FOR AN IMPLANTABLE RESTRICTION DEVICE 审中-公开
公开(公告)号：WO2011035006A3
公开(公告)日：2011-03-24
申请号：PCT/US2010/049094
申请日：2010-09-16
申请人： ETHICON ENDO-SURGERY, INC. , DLUGOS, Daniel, F. , BORK, Toralf , CHEN, Christine, H. , CRIVELLI, Rocco , KORVICK, Donna, L. , KRUMANAKER, David, T. , LESSEK, Timothy, P. , MARCOTTE, Amy, L. , MESSERLY, Jeffrey, D. , MUMAW, Daniel, J. , NALAGATLA, Anil, K. , PLESCIA, David, N. , SHELTON, Frederick, E. , SWAYZE, Jeffrey, S. , SWINDON, Patrick, J. , TSONTON, Mark , WOODRUFF, Scott, A.
发明人： DLUGOS, Daniel, F. , BORK, Toralf , CHEN, Christine, H. , CRIVELLI, Rocco , KORVICK, Donna, L. , KRUMANAKER, David, T. , LESSEK, Timothy, P. , MARCOTTE, Amy, L. , MESSERLY, Jeffrey, D. , MUMAW, Daniel, J. , NALAGATLA, Anil, K. , PLESCIA, David, N. , SHELTON, Frederick, E. , SWAYZE, Jeffrey, S. , SWINDON, Patrick, J. , TSONTON, Mark , WOODRUFF, Scott, A.
IPC分类号： A61F5/00 , A61F2/00
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A symmetrical drive system including a drive element associated with and engaging the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct is further provided. In accordance with an alternate embodiment an apparatus for regulating the functioning of a patient's organ or duct including an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. The tension element is composed of a flexible first member and a flexible second member, wherein the flexible first member is movable relative to the flexible second member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct.

2. 发明申请

WO2011035021A2 IMPLANTABLE RESTRICTION SYSTEM TENSION RELEASE MECHANISM 审中-公开
标题翻译：可伸缩限制系统张力释放机制
公开(公告)号：WO2011035021A2
公开(公告)日：2011-03-24
申请号：PCT/US2010/049115
申请日：2010-09-16
申请人： ETHICON ENDO-SURGERY, INC. , DLUGOS, Daniel, F. , BYRUM, Randal, T. , BORK, Toralf , CRIVELLI, Rocco , GARNER, Dean, L. , GINGGEN, Alec , HUEIL, Geoffrey, C. , KORVICK, Donna, L. , KRUMANAKER, David, T. , MARCOTTE, Amy, L. , MESSERLY, Jeffrey, D. , MOORE, Kyle, P. , MUMAW, Daniel, J. , NALAGATLA, Anil, K. , ORTIZ, Mark, S. , SHELTON, IV, Frederick E . , SMITH, Bret, W. , SWAYZE, Jeffrey, S. , SWINDON, Patrick, J. , TIMM, Richard, W. , THOMPSON, Eric W . , WEANER, Lauren S .
发明人： DLUGOS, Daniel, F. , BYRUM, Randal, T. , BORK, Toralf , CRIVELLI, Rocco , GARNER, Dean, L. , GINGGEN, Alec , HUEIL, Geoffrey, C. , KORVICK, Donna, L. , KRUMANAKER, David, T. , MARCOTTE, Amy, L. , MESSERLY, Jeffrey, D. , MOORE, Kyle, P. , MUMAW, Daniel, J. , NALAGATLA, Anil, K. , ORTIZ, Mark, S. , SHELTON, IV, Frederick E . , SMITH, Bret, W. , SWAYZE, Jeffrey, S. , SWINDON, Patrick, J. , TIMM, Richard, W. , THOMPSON, Eric W . , WEANER, Lauren S .
IPC分类号： A61F5/00 , A61F2/00
CPC分类号： A61F5/0053 , A61F2/0036 , A61F5/003 , A61F5/0056 , A61F5/0059
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A tension release mechanism is associated with the tension element.
摘要翻译：用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。紧固件设置在细长构件的第一端上。紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。张力元件设置成在细长构件内移动。驱动元件与张力元件相关联并与其接合，用于使张力元件控制由细长构件施加的抗张力抵靠患者身体器官或管道的张力。张力释放机构与张力元件相关联。

3. 发明申请

WO2011035036A1 IMPLANTABLE RESTRICTION SYSTEM WITH RELEASE MECHANISM 审中-公开
标题翻译：具有释放机制的可植入限制系统
公开(公告)号：WO2011035036A1
公开(公告)日：2011-03-24
申请号：PCT/US2010/049136
申请日：2010-09-16
申请人： ETHICON ENDO-SURGERY, INC. , DLUGOS, Daniel, F. , ADAMS, Thomas, E. , BYRUM, Randal, T. , BORK, Toralf , CHEN, Christine, H. , CONLON, Sean, P. , CRIVELLI, Rocco , GARNER, Dean, L. , GINGGEN, Alec , KRUMANAKER, David, T. , MARCOTTE, Amy, L. , NALAGATLA, Anil, K. , SMITH, Bret, W. , SWAYZE, Jeffrey, S. , TIMM, Richard, W.
发明人： DLUGOS, Daniel, F. , ADAMS, Thomas, E. , BYRUM, Randal, T. , BORK, Toralf , CHEN, Christine, H. , CONLON, Sean, P. , CRIVELLI, Rocco , GARNER, Dean, L. , GINGGEN, Alec , KRUMANAKER, David, T. , MARCOTTE, Amy, L. , NALAGATLA, Anil, K. , SMITH, Bret, W. , SWAYZE, Jeffrey, S. , TIMM, Richard, W.
IPC分类号： A61F5/00 , A61F2/00
CPC分类号： A61F5/003 , A61F2/0036 , A61F5/0053 , A61F5/0056 , A61F5/0059
摘要： An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element (32) is disposed for movement within the elongated member. A drive element is associated with and engaging the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A release mechanism (312) is provided for the tension element.
摘要翻译：用于调节患者器官或管道的功能的装置包括具有第一端和第二端的细长构件。紧固件设置在细长构件的第一端上。紧固件构造成接合细长构件的第二端，使得细长构件围绕器官或管道形成环。设置张力元件（32）以在细长构件内移动。驱动元件与张力元件相关联并与其接合，用于使张紧元件控制由细长构件施加的抵抗患者身体器官或管道的张力。为张力元件提供释放机构（312）。

4. 发明申请

WO2013143600A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS. 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法。
公开(公告)号：WO2013143600A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055798
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin, D. , LONG, Gary, L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik, S.
发明人： FELDER, Kevin, D. , LONG, Gary, L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik, S.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36067 , A61N1/0509
摘要： A system for stimulating the release of satiety hormone in a subject, the system comprising a stimulus device (11) having an electrical pulse generator (2) and multiple stimulus electrodes (3) adapted to apply electrical stimuli to a tissue of a gastrointestinal system of the subject, one or more time-dependently bioabsorbable or biofragmentable isolating layers (30) which cover at least one of the stimulus electrodes (3) such that the initially covered stimulus electrode (3) is exposed only after erosion of said one or more isolating layers (30).
摘要翻译：一种用于刺激受试者中饱腹感激素释放的系统，所述系统包括具有电脉冲发生器（2）和多个刺激电极（3）的刺激装置（11）和适于将电刺激施加到胃肠系统组织受试者，覆盖至少一个刺激电极（3）的一个或多个时间依赖性生物可吸收或生物可分散的隔离层（30），使得最初被覆盖的刺激电极（3）仅在所述一个或多个隔离层层（30）。

5. 发明申请

WO2013143608A1 ŁIMPLANTABLE SYSTEM FOR PROVIDING ELECTRICAL STIMULATION IN RESPONSE TO DETECTING AN INGESTION OF FOOD 审中-公开
标题翻译：用于提供电刺激以检测食物摄入的极限系统
公开(公告)号：WO2013143608A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055831
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S. , HARRIS, Jason , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele
发明人： BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S. , HARRIS, Jason , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36007 , A61F5/0026 , A61F2005/0016 , A61F2005/002 , A61N1/0509 , A61N1/0517
摘要： An implantable system for stimulating the release of satiety hormone in a subject comprises a stimulus device (11) which is implantable in the subject and adapted to apply an electrical stimulus to a tissue of a gastrointestinal system of said subject, and a detection device (2, 7, 8) which is implantable in the subject and adapted to continuously monitoring at least one of a mechanical characteristic and an electrical characteristic of the subject to detect an ingestion of food by said subject, wherein the detection device cooperates with the stimulus device (11) such that the stimulus device (11) applies said electrical stimulus in response to a detected ingestion of food.
摘要翻译：用于刺激受试者的饱腹感激素释放的可植入系统包括刺激装置（11），所述刺激装置可植入对象并适于对所述受试者的胃肠系统的组织施加电刺激，以及检测装置（2），7,8），其可植入对象中并且适于连续监测所述对象的机械特性和电特性中的至少一个，以检测所述对象摄取食物，其中所述检测装置与所述刺激装置（ 11），使得刺激装置（11）响应于检测到的食物摄取而应用所述电刺激。

6. 发明申请

WO2013143599A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS. 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法。
公开(公告)号：WO2013143599A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055795
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/36067 , A61N1/0509
摘要： A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1) having an electrical pulse generator (2) and stimulus electrodes (3) adapted to apply an electrical stimulus to a tissue, the stimulus device (1) being configured to time dependently move at least one of the stimulus electrodes (3) for time-dependently changing the location of application of the stimulus.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）和刺激电极（3）的刺激装置（1），刺激电极（3）适于对组织施加电刺激，刺激装置（1）被配置为时间依赖地移动至少一个所述刺激电极（3）以随时改变所述刺激的施加位置。

7. 发明申请

WO2013143609A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：WO2013143609A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055834
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/0509 , A61N1/36007
摘要： A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1 1 ) having an electrical pulse generator (2) and multiple stimulus electrodes (3) adapted to apply electrical stimuli to a tissue of a gastrointestinal system of the subject, the stimulus electrodes (3) being arranged at a distance to one another in multiple positions and the stimulus device (1 ) being configured to time-dependently switch selected ones of the stimulus electrodes (3) from an energized state to a non-energized state and vice versa for time-dependently changing the location of application of the stimulus.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）的刺激装置（11）和适于对受试者的胃肠系统的组织施加电刺激的多个刺激电极（3）刺激电极（3）在多个位置彼此间隔一定距离地布置，并且刺激装置（1）构造成将刺激电极（3）中的所选择的激励电极从激励状态时间依赖地切换到非通电状态，反之亦然，从而随时改变刺激应用的位置。

8. 发明申请

WO2013143603A1 DEVICES AND METHODS FOR THE TREATMENT OF METABOLIC DISORDERS 审中-公开
标题翻译：用于治疗代谢性疾病的装置和方法
公开(公告)号：WO2013143603A1
公开(公告)日：2013-10-03
申请号：PCT/EP2012/055813
申请日：2012-03-30
申请人： ETHICON ENDO-SURGERY, INC. , FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
发明人： FELDER, Kevin D. , LONG, Gary L. , ORTIZ, Mark Steven , PASTORELLI, Alessandro , D'ARCANGELO, Michele , BORK, Toralf , CRIVELLI, Rocco , MIGURAS, Mathilde , PFLEIDERER, Martin , TARDY, Yanik S.
IPC分类号： A61N1/05 , A61N1/04 , A61N1/36
CPC分类号： A61N1/0509 , A61N1/0408 , A61N1/0476 , A61N1/36007
摘要： A system for stimulating the release of satiety hormone in a subject includes a stimulus device (1) having an electrical pulse generator (2) and stimulus electrodes (3) adapted to apply an electrical stimulus to a tissue, the stimulus device (1) being adapted to be endoluminally introduced in a gastrointestinal system of the subject, and means (9, 16, 17, 42) for anchoring the stimulus device permanently in a target location inside the gastrointestinal system in a position in which the stimulus electrodes engage a tissue of said gastrointestinal system.
摘要翻译：用于刺激受试者中饱腹感激素释放的系统包括具有电脉冲发生器（2）的刺激装置（1）和适于对组织施加电刺激的刺激电极（3），刺激装置（1）为适于在受试者的胃肠系统中被内窥镜引入，以及用于将刺激装置永久地固定在胃肠系统内的目标位置中的装置（9,16,17,42），其中刺激电极接合刺激电极的组织说胃肠系统。

9. 发明申请

WO2012087669A1 PILL CATCHERS 审中-公开
公开(公告)号：WO2012087669A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/064634
申请日：2011-12-13
申请人： ETHICON ENDO-SURGERY, INC. , ORTIZ, Mark, S. , HESS, Christopher, J. , HARRIS, Jason, L. , VOEGELE, James, W. , ZEINER, Mark, S. , OVERMYER, Mark, D. , KRAIMER, Joseph, Bernard , SHIMIZU, Jeff , CRIVELLI, Rocco , TARDY, Yanik , UTARD, Thierry , BURGER, Juergen , BORK, Toralf , PFLEIDERER, Martin , CHOSSAT, Olivier
发明人： ORTIZ, Mark, S. , HESS, Christopher, J. , HARRIS, Jason, L. , VOEGELE, James, W. , ZEINER, Mark, S. , OVERMYER, Mark, D. , KRAIMER, Joseph, Bernard , SHIMIZU, Jeff , CRIVELLI, Rocco , TARDY, Yanik , UTARD, Thierry , BURGER, Juergen , BORK, Toralf , PFLEIDERER, Martin , CHOSSAT, Olivier
IPC分类号： A61M31/00 , A61B1/00 , A61F5/00 , A61K9/00 , A61B5/00 , A61J3/00
CPC分类号： A61B1/041 , A61B1/00147 , A61F5/0013 , A61M31/002
摘要： Devices are provided for the controlled delivery of a therapeutic to a targeted location within a body. More particularly, devices are provided for controlling the rate of passage of an orally administered pill through a body, as well as for controlling the delivery of a therapeutic within the pill at a specific location within the body. Various types of devices, generally referred to herein as "catchers," are provided that can actively catch a pill as it passes through a body. The catcher can hold the pill at a specific location within the body until a predetermined event occurs, such as partial or complete administration of a therapeutic within the pill. The catcher can then release the pill upon command and/or upon the occurrence of the predetermined event to allow the pill to pass out of the body. In other embodiments, various types of pills are provided that can actively engage a catcher and remain engaged with the catcher until a predetermined event occurs.
摘要翻译：提供了用于将治疗剂控制递送到体内目标位置的装置。更具体地，提供了用于控制经口施用的药丸通过身体的通过速率的装置，以及用于控制在体内特定位置处的丸剂内的治疗剂的递送。提供了在本文中通常被称为“捕获器”的各种类型的装置，其可以在通过身体时主动地捕捉药丸。捕获器可以将药丸保持在体内的特定位置，直到发生预定事件，例如在丸中部分或完全施用治疗剂。然后，捕手可以在命令和/或发生预定事件时释放药片以允许药丸从身体中流出。在其他实施例中，提供了可以主动地接合捕获器并保持与捕获器接合的各种类型的药丸，直到发生预定事件。

10. 发明申请

WO2014047241A2 MICROMACHINED ULTRASONIC SCALPEL WITH EMBEDDED PIEZOELECTRIC ACTUATOR 审中-公开
标题翻译：带嵌入式压电驱动器的微机械超声波标尺
公开(公告)号：WO2014047241A2
公开(公告)日：2014-03-27
申请号：PCT/US2013/060532
申请日：2013-09-19
申请人： ETHICON ENDO-SURGERY, INC.
发明人： DIETZ, Timothy G. , TARDY, Yanik , BURGER, Juergen , MARGAIRAZ, Philippe , BORK, Toralf
IPC分类号： A61B17/32
CPC分类号： A61B17/320068 , A61B17/3211 , A61B2017/00526 , H01L21/62
摘要： An ultrasonic core including a longitudinally elongated, generally planar waveguide defining an aperture extending from a first side of the waveguide toward a medial plane of the waveguide, and having a transducer element sized and shaped so as to substantially conform to the size and shape of the aperture and to be at least partially embedded within the waveguide. In other aspects, an ultrasonic core including a longitudinally elongated, generally planar silicon waveguide having at least one transducer element secured thereto and a wedge-shaped acoustic horn including an inclined side surface, characterized in that the inclined side surface is oriented along the {1,1,1} crystallographic plane of the silicon material. Also, methods of manufacturing the respective ultrasonic cores and ultrasonic handpieces for an ultrasonic surgical instruments incorporating such cores.
摘要翻译：超声波芯包括纵向细长的大体上平面的波导管，该波导管限定从波导管的第一侧朝向波导管的中间平面延伸的孔，并且具有换能器元件，换能器元件的尺寸和形状被设置成基本上符合孔径的大小和形状并且至少部分地嵌入波导内。在其它方面，超声波芯包括纵向细长的，大致平面的硅波导管，其具有固定在其上的至少一个换能器元件和包括倾斜侧表面的楔形声喇叭，其特征在于，倾斜侧表面沿着{1 ，1,1}硅材料的晶面。另外，制造用于包含这种芯的超声外科手术器械的各个超声波芯和超声波手持件的方法。

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