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1. 发明申请

WO2010112899A1 GAS CYLINDER FILLING SYSTEM 审中-公开
标题翻译：气缸灌装系统
公开(公告)号：WO2010112899A1
公开(公告)日：2010-10-07
申请号：PCT/GB2010/050508
申请日：2010-03-25
申请人： DOMINION TECHNOLOGY GASES LIMITED , LEE, Robert , SMITH, Graham , YULE, George Kynoch , SIM, Stewart , WATSON, Eric
发明人： LEE, Robert , SMITH, Graham , YULE, George Kynoch , SIM, Stewart , WATSON, Eric
IPC分类号： F17C7/04 , F17C13/08
CPC分类号： F17C9/02 , F17C5/06 , F17C13/083 , F17C2201/0109 , F17C2201/035 , F17C2201/054 , F17C2205/0107 , F17C2205/0157 , F17C2205/0332 , F17C2221/011 , F17C2221/014 , F17C2221/016 , F17C2221/017 , F17C2223/0153 , F17C2223/0161 , F17C2223/033 , F17C2225/0123 , F17C2227/0135 , F17C2227/0313 , F17C2227/04 , F17C2227/044 , F17C2250/032 , F17C2250/036 , F17C2250/0439 , F17C2250/0473 , F17C2250/0478 , F17C2250/0626 , F17C2260/013 , F17C2260/036 , F17C2265/06 , F17C2270/05 , F17C2270/059 , F17C2270/0745
摘要： A gas supply module including a container having at least one detachable side and within which is housed a gas conversion system. The detachable side provides a means for converting the gas supply module between a transportation mode and an operational mode. The gas conversion system is configured to convert a liquid gas contained within a tank to a pressurised gas supply.
摘要翻译：一种气体供应模块，包括具有至少一个可拆卸侧的容器，并且容纳有气体转换系统。可拆卸侧提供在输送模式和操作模式之间转换气体供应模块的装置。气体转换系统被配置为将容纳在罐中的液体气体转换成加压气体源。

2. 发明申请

WO2012135633A1 RECONSTRUCTIVE JOINT TUNNEL DRILLING LOCATOR 审中-公开
标题翻译：重建联合隧道钻井定位器
公开(公告)号：WO2012135633A1
公开(公告)日：2012-10-04
申请号：PCT/US2012/031482
申请日：2012-03-30
申请人： SMITH & NEPHEW, INC. , SMITH, Graham
发明人： SMITH, Graham
IPC分类号： A61B17/17
CPC分类号： A61B17/1714 , A61B17/1739 , A61B17/1778 , A61B2017/00407 , A61F2/08
摘要： An acromioclavicular joint guide for forming multiple drill tunnels spaced apart by a predetermined distance employs two drill guides in a pivoting arrangement allowing one drill guide to pivot around the axis of the other. The drill guides are each disposed in a respective sleeve of a pivot block for insertion toward the surgical member along nonintersecting axes defined by the sleeve. An elongated arm attaches to the pivot block at a proximate end and has a aimer point at a distal end, in which the arm may extend around the surgical member via an inverted portion or bend such that the aimer point is on the insertion axis of the primary drill guide. In this manner the aimer point locates an exit of the hole from the insertion point defined by the primary drill guide, and the pivotal drill guide defines a second tunnel at the predetermined distance.
摘要翻译：用于形成间隔开预定距离的多个钻孔隧道的肩锁关节引导件采用两个钻孔引导器，该枢转布置允许一个钻子引导件围绕另一钻杆枢转。钻子引导件各自设置在枢转块的相应套筒中，用于沿着由套筒限定的不间断轴线朝向外科手术构件插入。细长臂在近端附接到枢转块，并且在远端具有瞄准器点，其中臂可以经由倒置部分或弯曲部围绕手术构件延伸，使得瞄准器点在所述插入轴线上主钻指南。以这种方式，瞄准器点将孔的出口从由主钻导向器限定的插入点定位，并且枢转钻子引导器以预定距离限定第二隧道。

3. 发明申请

WO2012040151A3 ISOTOPIC CARBON CHOLINE ANALOGS 审中-公开
公开(公告)号：WO2012040151A3
公开(公告)日：2012-03-29
申请号：PCT/US2011/052275
申请日：2011-09-20
申请人： GE HEALTHCARE LIMITED , IMPERIAL COLLEGE , MEDI-PHYSICS, INC. , ABOAGYE, Eric, Ofori , ROBINS, Edward George , SMITH, Graham , LUTHRA, Sajinder
发明人： ABOAGYE, Eric, Ofori , ROBINS, Edward George , SMITH, Graham , LUTHRA, Sajinder
IPC分类号： C07C213/00 , C07C213/02 , C07C213/06 , C07C215/08 , C07C217/10
摘要： Novel choline - derived radiotracer (s) having an isotopic carbon for Positron Emission Tomography (PET) or Single Photon Emission Computed Tomography (SPECT) imaging of disease states related to altered choline metabolism (e.g., tumor imaging of prostate, breast, brain, esophageal, ovarian, endometrial, lung and prostate cancer - primary tumor, nodal disease or metastases).

4. 发明申请

WO2012030632A1 MODIFIED FASTENER AND INSERTION TOOL 审中-公开
标题翻译：改装紧固件和插入工具
公开(公告)号：WO2012030632A1
公开(公告)日：2012-03-08
申请号：PCT/US2011/049251
申请日：2011-08-26
申请人： SMITH & NEPHEW, INC. , CANIZARES, Eduardo, Antonio, Jr. , SMITH, Graham
发明人： CANIZARES, Eduardo, Antonio, Jr. , SMITH, Graham
IPC分类号： F16B23/00 , A61B17/88 , B25B15/00 , B25B23/10 , A61B17/86
CPC分类号： F16B23/0007 , A61B17/8615 , A61B17/862 , A61B17/888 , A61B17/8891 , B21K1/56 , B25B15/005 , B25B23/101 , F16B23/003 , F16B23/0061 , Y10T29/49826
摘要： According to example configurations, a modified screw head (150) includes one or more slots or grooved channels (210-1). A screwdriver device includes a tip that can be inserted into a cavity in the head of the screw to torque the modified screw into an object. The screwdriver device (690) includes a sleeve. The sleeve (250) slides along a shaft of the screwdriver. The sleeve includes inward protruding posts (275) e.g., pins, fingers, etc. Sliding of the sleeve over the screw's head requires that inward protruding posts in the sleeve be aligned with the grooves on the sidewall of the screw's head. Subsequent to aligning and sliding the sleeve into the grooved channels of the screw's head, the user twists the sleeve to secure the screw head to the screwdriver's tip. The sleeve (250) can be spring - loaded to pull the head of the screw toward a handle end of the screwdriver after a user releases the sleeve.
摘要翻译：根据示例性构造，改进的螺钉头（150）包括一个或多个槽或沟槽通道（210-1）。螺丝刀装置包括能够插入到螺钉的头部中的空腔中的尖端，以将改进的螺钉扭转成物体。螺丝刀装置（690）包括套筒。套筒（250）沿螺丝刀的轴滑动。套筒包括向内突出的柱（275），例如销，手指等。将套筒滑动在螺钉头部上需要套筒中的向内突出的柱与螺钉头部的侧壁上的凹槽对准。在将套筒对准和滑动到螺钉头部的槽形通道中之后，用户扭转套筒以将螺钉头固定到螺丝刀的尖端。套筒（250）可以是弹簧加载的，以在用户释放套筒之后将螺钉的头部朝着螺丝刀的手柄端拉动。

5. 发明申请

WO2011077095A1 QUINOLINE DERIVATIVES USED AS PET IMAGING AGENTS 审中-公开
标题翻译：用作PET成像剂的喹啉衍生物
公开(公告)号：WO2011077095A1
公开(公告)日：2011-06-30
申请号：PCT/GB2010/002325
申请日：2010-12-22
申请人： IMPERIAL INNOVATIONS LIMITED , ABOAGYE, Eric , PISANESCHI, Frederica , SPIVEY, Alan , SMITH, Graham
发明人： ABOAGYE, Eric , PISANESCHI, Frederica , SPIVEY, Alan , SMITH, Graham
IPC分类号： C07D215/54 , C07D401/12 , C07H5/02 , C07H19/056
CPC分类号： C07D215/54 , A61K31/4706 , A61K31/4709 , A61K31/706 , A61K45/06 , C07D401/12 , C07H19/056
摘要： There is provided compounds of formula (I), wherein R 1 , R 2 , X 1 , X 2, and X 3 have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful as positron emission tomography (PET) imaging agents, useful in the treatment of diseases in which inhibition of epidermal growth factor receptor tyrosine kinase activity or the inhibition of HER2 activity is desired and/or required, and useful in the treatment of cancer.
摘要翻译：提供式（I）化合物，其中R1，R2，X1，X2和X3具有说明书中给出的含义及其药学上可接受的盐，该化合物可用作正电子发射断层摄影（PET）成像剂，有用在治疗其中期望和/或需要抑制表皮生长因子受体酪氨酸激酶活性或抑制HER2活性的疾病中，并且可用于治疗癌症。

6. 发明申请

WO2010023457A1 NUCLEOSIDE ANALOGUES USEFUL AS POSITRON EMISSION TOMOGRAPHY (PET) IMAGING AGENTS 审中-公开
标题翻译：核素类似物可用作POSITRON排放成像（PET）成像剂
公开(公告)号：WO2010023457A1
公开(公告)日：2010-03-04
申请号：PCT/GB2009/002096
申请日：2009-08-28
申请人： IMPERIAL INNOVATIONS LIMITED , ABOAGYE, Eric, Ofori , SMITH, Graham
发明人： ABOAGYE, Eric, Ofori , SMITH, Graham
IPC分类号： A61K31/7072 , C07H19/073 , C07H19/067
CPC分类号： C07H19/073 , C07H5/10 , C07H23/00
摘要： The invention provides compounds that comprise a 4'-thio nucleoside that is a derivative of 4'-thiothymidine or 4'-thio-2'-deoxyuridine comprising a positron or single photon emitting radioisotope or corresponding non-radioactive isotope attached via a triazole link to the N-3 position. Methods for preparing such compounds and uses of the compounds in medicine are also provided.
摘要翻译：本发明提供了包含4'-硫代胸苷或4'-硫代-2'-脱氧尿苷衍生物的4'-硫代核苷的化合物，其包含通过三唑连接物连接的正电子或单光子发射放射性同位素或相应的非放射性同位素到N-3位置。还提供了制备这些化合物的方法和该化合物在医药中的用途。

7. 发明申请

WO2012103535A1 SURGICAL AIMING DEVICE 审中-公开
标题翻译：手术瞄准装置
公开(公告)号：WO2012103535A1
公开(公告)日：2012-08-02
申请号：PCT/US2012/023055
申请日：2012-01-29
申请人： SMITH & NEPHEW, INC. , SMITH, Graham
发明人： SMITH, Graham
IPC分类号： A61B17/17
CPC分类号： A61B17/1764 , A61B17/1714 , A61B2017/00407
摘要： A hinged pivoting guide for positioning a femoral tunnel in anterior cruciate ligament (ACL) reconstruction locates a drilling hole for placement that optimally penetrates a minimal depth of soft tissue (skin, muscle, etc.) yet directs drilling into a sufficiently rigid and structurally sound area of the femur. The hinged guide allows placement of an aimer point at a desired drilling exit location on the femur. The hinge is adapted to secure the aimer at a degree of rotation about an axis defined by the hinge rotation, such that the axis passes through the aimer point throughout rotation of the hinge while maintaining the aimer point in line with an insertion guide slideably movable through the aperture in the handle, the aperture defined by an insertion axis extending toward the aimer point such that the aimer point remains disposed at the intersection of the hinge axis and the insertion axis.
摘要翻译：用于将股骨隧道定位在前十字韧带（ACL）重建中的铰接枢转引导器定位用于放置的钻孔，其最佳地穿透软组织（皮肤，肌肉等）的最小深度，但是将钻孔引导到足够刚性和结构声音股骨面积铰链引导件允许将瞄准器点放置在股骨上期望的钻孔出口位置。铰链适于将瞄准器固定在围绕由铰链旋转限定的轴线的旋转角度处，使得轴线在铰链旋转期间通过瞄准器点，同时保持瞄准器点与可滑动地移动的插入导向手柄中的孔径，由朝向瞄准器点延伸的插入轴限定的孔，使得瞄准器点保持设置在铰链轴线和插入轴线的交叉点处。

8. 发明申请

WO2004060173A1 SURGICAL PROCEDURES AND INSTRUMENTS 审中-公开
标题翻译：手术程序和仪器
公开(公告)号：WO2004060173A1
公开(公告)日：2004-07-22
申请号：PCT/US2003/041853
申请日：2003-12-30
申请人： SMITH & NEPHEW, INC. , HARVIE, Fraser , SMITH, Graham , SAMPLE, Phillip, B. , MCCARTHY, Gary, R. , JAMES, Adam , RICHARDSON, Peter , CARTER, Sally, L.
发明人： HARVIE, Fraser , SMITH, Graham , SAMPLE, Phillip, B. , MCCARTHY, Gary, R. , JAMES, Adam , RICHARDSON, Peter , CARTER, Sally, L.
IPC分类号： A61B17/04
CPC分类号： A61B17/3472 , A61B17/00491 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B17/0642 , A61B17/0644 , A61B17/068 , A61B17/1615 , A61B17/1622 , A61B17/1637 , A61B17/1684 , A61B17/686 , A61B17/8819 , A61B17/8836 , A61B17/8869 , A61B2017/005 , A61B2017/0404 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/0427 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0446 , A61B2017/0458 , A61B2017/0462 , A61B2017/0647 , A61F2/0805 , A61F2002/0888 , A61F2210/0085
摘要： Surgical instruments and methods are provided. In one aspect, a method of securing a fixation device within an opening in a tissue is provided, including delivering a material in a flowable state to said opening, and changing the state of the material so that the material forms an interference fit that secures the fixation device in the opening.
摘要翻译：提供手术器械和方法。在一个方面，提供了一种将固定装置固定在组织内的开口内的方法，包括将材料以可流动状态传送到所述开口，并且改变材料的状态，使得材料形成干涉配合，固定装置在开口。

9. 发明申请

WO2003036899A2 APPARATUS AND METHODS FOR PROVIDING SELF-CONFIGURING COMPUTER NETWORKS 审中-公开
标题翻译：提供自配置计算机网络的装置和方法
公开(公告)号：WO2003036899A2
公开(公告)日：2003-05-01
申请号：PCT/CA2002/001617
申请日：2002-10-24
申请人： GENTE SOLUTIONS LTD. , SMITH, Graham , ETHERIDGE, Karen , CHAPMAN, Ryan , JOLY, Jean-Pierre
发明人： SMITH, Graham , ETHERIDGE, Karen , CHAPMAN, Ryan , JOLY, Jean-Pierre
IPC分类号： H04L29/00
CPC分类号： H04L29/06 , H04L29/12207 , H04L61/20
摘要： A self-configuring network according to a preferred embodiment of the invention comprises a software component that allows devices on the network to take control over their configurations This software component allows devices on the LAN to become functional members of the network without manual configuration of their network components. It does this by providing the network component of each device with means to obtain values for its own configuration parameters (also known as "configuration objects") from other devices on the network, and help other components to obtain values for their configuration parameters.
摘要翻译：根据本发明的优选实施例的自配置网络包括允许网络上的设备控制其配置的软件组件。该软件组件允许LAN上的设备成为网络的功能成员，而无需手动配置其网络组件。它通过为每个设备的网络组件提供从网络上其他设备获取自身配置参数（也称为“配置对象”）的值的手段，并帮助其他组件获取其配置参数的值。

10. 发明申请

WO2012061733A1 DRILL GUIDE DEPTH STOP 审中-公开
标题翻译：钻孔指导深度停止
公开(公告)号：WO2012061733A1
公开(公告)日：2012-05-10
申请号：PCT/US2011/059374
申请日：2011-11-04
申请人： SMITH & NEPHEW, INC. , SMITH, Graham
发明人： SMITH, Graham
IPC分类号： A61B17/17
CPC分类号： A61B17/1714 , A61B17/1739 , A61B17/1778 , A61B2017/00407 , A61B2017/0046 , A61B2090/034
摘要： The present invention relates to a drill guide for positioning a bone tunnel in which the drill guide comprises a depth stop. The drill guide comprises an aimer arm and a drill sleeve, and includes a sleeve channel. The drill sleeve is moveable towards and away from the distal end of the aimer arm within the sleeve channel, and the depth stop is adjustable to provide a fixed drilling path length, irrespective of the distance between drill sleeve and distal end of the aimer arm.
摘要翻译：本发明涉及一种用于定位骨隧道的钻子引导器，其中钻子引导件包括深度止挡件。钻子引导器包括瞄准器臂和钻套，并且包括套筒通道。钻套筒可以在套筒通道内朝向和远离瞄准器臂的远端移动，并且深度限位器是可调节的，以提供固定的钻孔路径长度，而与钻套筒和瞄准器臂的远端之间的距离无关。

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