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1. 发明申请

WO2019135216A1 IMPLANTATION TOOL AND PROTOCOL FOR OPTIMIZED SOLID SUBSTRATES PROMOTING CELL AND TISSUE GROWTH 审中-公开
公开(公告)号：WO2019135216A1
公开(公告)日：2019-07-11
申请号：PCT/IL2018/051413
申请日：2018-12-30
申请人： CARTIHEAL (2009) LTD.
发明人： ALTSCHULER, Nir
IPC分类号： A61F2/30 , A61B17/16 , A61B17/17 , A61F2/46
CPC分类号： A61F2/30756 , A61B17/1604 , A61B17/1615 , A61B17/1635 , A61B17/1659 , A61B17/17 , A61B17/1764 , A61B2017/0046 , A61F2/4618 , A61F2002/30759
摘要： This invention provides methods for optimal implantation of a solid substrate for promoting cell or tissue growth or restored function in an osteochondral, bone or cartilage tissue in a subject in need thereof. The methods include selecting and preparing a solid substrate for promoting cell or tissue growth or restored function for implantation, which solid substrate has a length and width or that promotes a tight fit within the boundaries of the implantation site and is further characterized by a height sufficient such that when a first terminus of said solid substrate is implanted within a bone in a site for implantation, a second terminus of said solid substrate is at a height at least 2 mm less than an articular cartilage layer surface or is proximal to a tide mark region in said implantation site and optionally applying a biocompatible polymer layer to an apical surface of said implant, which layer does not exceed the articular cartilage layer surface in height. Tools for implementation of optimal positioning are described including a unique tool (5-120) for trimming cartilage at the implantation site.

2. 发明申请

WO2016178226A9 OPTIMIZED SOLID SUBSTRATES, TOOLS FOR USE WITH SAME AND USES THEREOF FOR PROMOTING CELL AND TISSUE GROWTH 审中-公开
标题翻译：优化的固体基质，与其一起使用的工具及其用于促进细胞和组织生长的用途
公开(公告)号：WO2016178226A9
公开(公告)日：2018-01-25
申请号：PCT/IL2016050469
申请日：2016-05-04
申请人： CARTIHEAL (2009) LTD
发明人： ALTSCHULER NIR , GOREN AMIR
IPC分类号： A61B17/16 , A61B17/17 , A61B17/92
CPC分类号： A61B17/1604 , A61B17/1675 , A61B17/1764 , A61B2017/922 , A61F2/28 , A61F2/30756 , A61F2/4618 , A61F2002/2835
摘要： [00520] This invention provides optimized solid substrates for promoting cell or tissue growth or restored function, which solid substrate comprises aragonite and is characterized by a specific fluid uptake capacity value of at least 75%, or a contact angle value of less than 60 degrees when in contact with a fluid and which is further characterized by tapered sides and tools for implantation of optimized solid substrates.
摘要翻译：本发明提供了用于促进细胞或组织生长或恢复功能的优化的固体基质，该固体基质包含文石并且特征在于特定的流体摄取能力值至少75％或接触角值小于60度当与流体接触并且其特征还在于锥形侧面和用于植入优化的固体基底的工具。

3. 发明申请

WO2018009860A1 DEVICES AND METHODS FOR PERFORMING ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION USING PATIENT-SPECIFIC DRILL GUIDE 审中-公开
标题翻译：使用患者特异性钻孔导向器进行前内侧腱索重建的装置和方法
公开(公告)号：WO2018009860A1
公开(公告)日：2018-01-11
申请号：PCT/US2017/041186
申请日：2017-07-07
申请人： BIOMET SPORTS MEDICINE, LLC
发明人： MAXSON, William , STONE, Kevin T. , MERIDEW, Jason D. , SAUTTER, Nathan M.
IPC分类号： A61B17/17
CPC分类号： A61B17/1714 , A61B17/1633 , A61B17/1764 , A61B34/10 , A61B2017/00477 , A61B2017/568 , A61B2034/108
摘要： A guide for drilling a tunnel in a knee joint having intercondylar roof and tibial eminence. The guide can comprise a guide assembly having a positioning member including an inferior end, and a guide arm extending from the positioning member including a trochlear tip; and a drill sleeve having a body attached to the inferior end, an aperture extending along a drilling axis, and a distal end having a patient-specific surface configured to engage an anterior surface of the tibia. A method of producing a tibial tunnel can comprise inserting a trochlear tip of a guide arm between the tibial eminence and the intercondylar roof, adjusting a position of a positioning member connected to the guide arm, engaging a patient-specific tip of a drill sleeve connected to the positioning member with a surface of a tibia, and inserting a drill bit through the drill sleeve to drill a tibial tunnel.
摘要翻译：在髁间顶和胫骨隆起的膝关节内钻隧道的指南。所述引导件可以包括引导组件，所述引导组件具有包括下端的定位构件以及从包括滑车顶端的定位构件延伸的引导臂; 以及具有附接到所述下端的主体，沿着钻孔轴线延伸的孔的钻套以及具有构造成接合所述胫骨的前表面的患者特异性表面的远端。制造胫骨隧道的方法可以包括将引导臂的滑车尖端插入在胫骨隆凸和髁间顶部之间，调节连接到引导臂的定位构件的位置，将连接到钻头套管的患者特定尖端到具有胫骨表面的定位构件，并且将钻头插入穿过钻套以钻出胫骨隧道。

4. 发明申请

WO2017027460A1 METHODS FOR FACILITATING INDIVIDUALIZED KINEMATICALLY ALIGNED TOTAL KNEE REPLACEMENTS AND DEVICES THEREOF 审中-公开
标题翻译：促进个性化动态对齐总共更换的方法及其设备
公开(公告)号：WO2017027460A1
公开(公告)日：2017-02-16
申请号：PCT/US2016/046009
申请日：2016-08-08
申请人： ITKR SOFTWARE LLC
发明人： DOSSETT, Robert, Alan , DOSSETT, Harold, Gene
IPC分类号： A61F2/38
CPC分类号： A61B34/10 , A61B17/155 , A61B17/157 , A61B17/1764 , A61B34/25 , A61B2017/568 , A61B2034/102 , A61B2034/105 , A61B2034/107 , A61B2034/108 , A61B2034/252 , A61B2034/256 , G06F19/00 , G16H50/50
摘要： Methods, non-transitory computer readable media, and individualized kinematic total knee replacement (TKR) analysis computing devices that obtain prosthesis data for a prosthesis. Anatomical and pathoanatomical data for a patient is determined. The anatomical data comprises at least a coronal mechanical lateral distal femoral angle and a posterior condylar axis that is specific to the patient. Bone and cartilage resection data is determined based on the prosthesis data, the anatomical data, and the pathoanatomical data. In one example, a recommended three-dimensional total knee replacement surgeon plan for the patient is output via a graphical interface. The recommended three-dimensional total knee replacement surgeon plan comprises the bone and cartilage resection data for facilitating implantation of the prosthesis in the patient. In another example, one or more femoral and tibial guides are formed based on the three- dimensional total knee replacement surgeon plan, wherein the femoral and tibial guides are specific to the patient.
摘要翻译：方法，非暂时计算机可读介质和获得假体假体数据的个体化运动学全膝关节置换（TKR）分析计算装置。确定患者的解剖和病理解剖数据。解剖数据包括至少冠状机械侧向远端股骨角度和对患者特异的后髁轴线。基于假体数据，解剖数据和病理解剖数据确定骨和软骨切除数据。在一个示例中，通过图形界面输出针对患者的推荐的三维全膝关节置换外科医生计划。推荐的三维全膝关节置换手术计划包括骨和软骨切除数据，以便于在患者体内植入假体。在另一个示例中，基于三维全膝关节置换外科医生计划形成一个或多个股骨和胫骨引导件，其中股骨和胫骨引导件对患者是特定的。

5. 发明申请

WO2017004056A1 ROBOTIC SYSTEMS AND METHODS FOR CONTROLLING A TOOL REMOVING MATERIAL FROM A WORKPIECE 审中-公开
标题翻译：用于控制工具去除材料的机器人系统和方法
公开(公告)号：WO2017004056A1
公开(公告)日：2017-01-05
申请号：PCT/US2016/039842
申请日：2016-06-28
申请人： MAKO SURGICAL CORP.
发明人： MOCTEZUMA DE LA BARRERA, Jose, Luis , BOWLING, David, Gene , MALACKOWSKI, Donald, W. , ROESSLER, Patrick , BEER, Joel, N.
IPC分类号： B25J11/00 , A61B34/30 , A61B34/20 , A61B17/16
CPC分类号： A61B34/30 , A61B17/1764 , A61B34/10 , A61B34/20 , A61B34/32 , A61B90/39 , A61B2034/105 , A61B2034/2051 , A61B2034/2055 , A61B2034/2057 , A61B2034/2063 , A61B2090/3945 , B25J9/1664 , B25J11/0055 , G05B19/40937 , G05B2219/35021 , G05B2219/45168
摘要： Robotic systems and methods for controlling a tool to remove material from a workpiece. Workpieces such as bones are often non-homogenous and have varying density distributions throughout their volumes. In some embodiments, the systems and methods control the feed rate of the tool, the tool path of the tool, and the rotational speed of the tool based on the density distribution in order to provide a desired outcome for a surgical procedure.
摘要翻译：用于控制工具以从工件移除材料的机器人系统和方法。诸如骨头的工件通常是不均匀的，并且在整个体积中具有不同的密度分布。在一些实施例中，系统和方法基于密度分布来控制工具的进给速率，工具的刀具路径和工具的转速，以便为外科手术提供期望的结果。

6. 发明申请

WO2016191713A1 FLEXIBLY PLANNED KITTED KNEE PROTOCOL 审中-公开
标题翻译：灵活计划的KITTED KNEE协议
公开(公告)号：WO2016191713A1
公开(公告)日：2016-12-01
申请号：PCT/US2016/034719
申请日：2016-05-27
申请人： BIOMET MANUFACTURING, LLC
发明人： BROWN, David R. , UTHGENANNT, Brian , METZGER, Robert
IPC分类号： A61B34/10
CPC分类号： A61B34/10 , A61B17/1764 , A61B90/06 , A61B2034/105 , A61B2034/108 , A61B2034/2048 , A61B2090/061 , A61B2090/3966
摘要： A method of planning and preparing for a total knee arthroplasty procedure, the method comprising: generating three-dimensional models of a tibia and a femur of a patient; sizing the tibia and the femur to within a range based on the three-dimensional models; selecting a resection tool for each of the tibia and femur based on the three-dimensional models; and packaging the resection tools. A method of planning and preparing for a surgical procedure can comprise: generating a three-dimensional bone model for one or more bones; sizing the one or more bones based on the three-dimensional model; recording a surgical plan based on the three-dimensional bone model; selecting a first surgical tool for the one or more bone based on the surgical plan; and evaluating selection of a second surgical tool based on a performance parameter of the first surgical tool.
摘要翻译：一种计划和准备全膝关节置换术的方法，所述方法包括：产生患者的胫骨和股骨的三维模型; 将胫骨和股骨的尺寸调整到基于三维模型的范围内; 基于三维模型为每个胫骨和股骨选择切除工具; 并包装切除工具。规划和准备外科手术的方法可以包括：为一个或多个骨骼生成三维骨模型; 基于三维模型确定一个或多个骨骼的尺寸; 记录基于三维骨骼模型的手术计划; 基于手术计划选择用于所述一个或多个骨的第一外科手术工具; 以及基于所述第一外科手术工具的性能参数来评估第二外科手术工具的选择。

7. 发明申请

WO2016173626A1 METHOD AND DEVICE FOR DETERMINING GEOMETRIC PARAMETERS FOR TOTAL KNEE REPLACEMENT SURGERY 审中-公开
标题翻译：用于确定全膝关节置换手术的几何参数的方法和装置
公开(公告)号：WO2016173626A1
公开(公告)日：2016-11-03
申请号：PCT/EP2015/059202
申请日：2015-04-28
申请人： BRAINLAB AG
发明人： HAIDACHER, Florian , NEUBAUER, Timo , SCHUBERT, Mario
IPC分类号： A61B17/15
CPC分类号： A61B34/10 , A61B17/155 , A61B17/157 , A61B17/1703 , A61B17/1764 , A61B2034/108 , A61B2034/2055 , A61B2090/3937 , G06F19/00 , G06T7/0016 , G06T7/60 , G06T2207/10081 , G06T2207/10088 , G06T2207/10104 , G06T2207/10132 , G06T2207/30008
摘要： The present invention relates to a data processing method performed by a computer (6), for determining geometric parameters of a phantom leg bone (1, 2) using a cutting guide (3) that defines a cutting plane (4) and that is configured to abut a predetermined surface section (5) of the phantom leg bone (1, 2), the method comprising the following steps: - acquiring cutting guide position data describing the spatial position of the cutting guide (3); - acquiring, from an anatomical atlas or from an image of the phantom patient, relative position data describing the spatial position of a first mechanical axis point (7) relative to the predetermined surface section (5) of the phantom leg bone (1, 2); - determining, based on the cutting guide position data and the relative position data, first axis point position data describing the spatial position of the first mechanical axis point (7) of the phantom leg bone (1, 2). The present invention further relates to a corresponding cutting guide and a corresponding computer program and computer.
摘要翻译：本发明涉及一种由计算机（6）执行的用于使用限定切割平面（4）的切割引导件（3）确定幻影腿骨（1,2）的几何参数并且被配置的数据处理方法邻接假肢腿骨（1,2）的预定表面部分（5），该方法包括以下步骤： - 获取描述切割引导件（3）的空间位置的切割引导位置数据; - 从解剖图谱或从幻影患者的图像获取描述第一机械轴点（7）相对于假肢腿骨（1,2）的预定表面部分（5）的空间位置的相对位置数据）; - 基于所述切割引导位置数据和所述相对位置数据确定描述所述虚拟腿骨（1,2）的第一机械轴点（7）的空间位置的第一轴点位置数据。本发明还涉及相应的切割引导件和相应的计算机程序和计算机。

8. 发明申请

WO2016094298A1 IMPLANT BASED PLANNING, DIGITIZING, AND REGISTRATION FOR TOTAL JOINT ARTHROPLASTY 审中-公开
标题翻译：基于植入式计划，数字化和注册的总关节炎
公开(公告)号：WO2016094298A1
公开(公告)日：2016-06-16
申请号：PCT/US2015/064258
申请日：2015-12-07
申请人： THINK SURGICAL, INC.
发明人： BONNY, Daniel Patrick , ZUHARS, Joel , HOPPE, Michael E.
IPC分类号： A61B34/10 , A61B34/20 , A61F2/28 , A61B34/30
CPC分类号： A61B34/10 , A61B17/15 , A61B17/154 , A61B17/1675 , A61B17/1703 , A61B17/1764 , A61B34/20 , A61B34/30 , A61B2034/102 , A61F2/389 , A61F2002/3069 , A61F2002/4632 , A61F2002/4633
摘要： A system and process for performing orthopedic surgery is provided that uses a patient's existing implant as a registration tool in an orthopedic surgical procedure. The systems and processes may be used with computer assisted systems or navigation systems to aid in the removal of bone, bone cement, or a bone prosthesis, typically a bone prosthesis used in hip replacement surgery, knee replacement surgery, and the like. The removal of the prosthesis may be done by conventional methods, with navigation systems, robotic assistance or articulating hand held systems. The removal of bone and/or bone cement may be performed with navigated systems, robotic systems, articulating hand-held systems and combinations thereof.
摘要翻译：提供了一种用于执行整形外科手术的系统和方法，其使用患者的现有植入物作为整形外科手术中的登记工具。系统和过程可以与计算机辅助系统或导航系统一起使用，以帮助去除骨，骨水泥或骨假体，通常用于髋关节置换手术，膝关节置换手术等中的骨假体。假体的移除可以通过常规方法，导航系统，机器人辅助或铰接手持系统来完成。可以使用导航系统，机器人系统，铰接手持系统及其组合来执行骨和/或骨水泥的去除。

9. 发明申请

WO2016081094A1 GAP REFERENCING FEMORAL SIZER 审中-公开
标题翻译： GAP参考FEMORAL SIZER
公开(公告)号：WO2016081094A1
公开(公告)日：2016-05-26
申请号：PCT/US2015/055087
申请日：2015-10-12
申请人： ZIMMER, INC.
发明人： TOLER, Jason S.
IPC分类号： A61B17/15 , A61B17/02
CPC分类号： A61B17/1764 , A61B17/025 , A61B17/155 , A61B17/88 , A61B19/46 , A61B2017/0268 , A61B2017/90 , A61B2019/461 , A61B2090/061 , A61B2090/067 , A61F2/4657 , A61F2002/4658
摘要： A knee arthroplasty assembly for use in a patient's knee joint including a tibia and a femur is disclosed. The assembly can include a tool (10), a first accessory (90), and a second accessory (100). The tool can include a tibial component (14) configured for placement against the tibia and a femoral component (16) configured for placement against the femur. The femoral component can be moveably coupled to the tibial component to place the patient's knee joint in tension by separating the tibia and the femur. The first accessory can be removeably coupled to the tibial component of the tool. The second accessory can be referenced to the first accessory and can have a reference indicator (114A, 114B) that references the femur for determining a size of the femur.
摘要翻译：公开了一种用于包括胫骨和股骨的患者膝关节的膝关节置换组件。组件可以包括工具（10），第一附件（90）和第二附件（100）。该工具可以包括被配置为抵靠胫骨放置的胫骨部件（14）和构造成用于抵靠股骨的股骨部件（16）。股骨部件可以可移动地联接到胫骨部件，以通过分离胫骨和股骨来使患者的膝关节处于张紧状态。第一附件可以可移除地联接到工具的胫骨部件。第二附件可以参考第一附件，并且可以具有引用股骨以确定股骨的尺寸的参考指示器（114A，114B）。

10. 发明申请

WO2016063279A2 A KIT INCLUDING A GUIDING SYSTEM AND A BONE MATERIAL REMOVAL DEVICE AND METHOD OF USE THEREOF 审中-公开
标题翻译：包括引导系统和骨材料去除装置的套件及其使用方法
公开(公告)号：WO2016063279A2
公开(公告)日：2016-04-28
申请号：PCT/IL2015051033
申请日：2015-10-19
申请人： T A G MEDICAL DEVICES AGRICULTURE COOPERATIVE LTD
发明人： MIROCHINIK ARYEH , SITRY HAGAY , HAZIZA RAFI , WEISMAN RAN
IPC分类号： A61B17/16
CPC分类号： A61B17/1617 , A61B17/16 , A61B17/1675 , A61B17/1714 , A61B17/1764
摘要： A kit including a guiding system and a bone material removal device, including an arcuate element, a guiding element configured to be attached to the arcuate element, a cannula, slidably insertable into a portion of the arcuate element, a cannulated bone material removal device having a longitudinal shaft, which is axially displaceable within the cannula.
摘要翻译：一种包括引导系统和骨材料去除装置的试剂盒，包括弓形元件，构造成连接到弓形元件的引导元件，可滑动地插入到弓形元件的一部分中的插管，插管骨材料去除装置，其具有纵轴，其可在套管内轴向移位。

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