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1. 发明申请

WO2003079812A1 HERBAL NUTRACEUTICALS AND A PROCESS FOR PREPARING THE SAME 审中-公开
标题翻译：草药营养及其制备方法
公开(公告)号：WO2003079812A1
公开(公告)日：2003-10-02
申请号：PCT/IB2002/000976
申请日：2002-03-25
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH , QAZI, Gulam, Nabi , TICKOO, Chuni, Lal , GUPTA, Ashok, Kumar , GUPTA, Devinder, Kumar , JAGGI, Bupinder, Singh , SINGH, Ram, Pal , SINGH, Gurdeep , CHANDAN, Bal, Krishan , SURI, Krishan, Avtar , SATTI, Naresh, Kumar , GUPTA, Vishwanath , BAKSHI, Santosh, Kumar , BEDI, Kasturi, Lal , SURI, Om, Parkash , SURI, Satish, Chander , SOMAL, Preeti , SINGH, Surjit , KHAJURIA, Anamika , GANJOO, Sudesh, Kumar , KUMAR, Arun
发明人： QAZI, Gulam, Nabi , TICKOO, Chuni, Lal , GUPTA, Ashok, Kumar , GUPTA, Devinder, Kumar , JAGGI, Bupinder, Singh , SINGH, Ram, Pal , SINGH, Gurdeep , CHANDAN, Bal, Krishan , SURI, Krishan, Avtar , SATTI, Naresh, Kumar , GUPTA, Vishwanath , BAKSHI, Santosh, Kumar , BEDI, Kasturi, Lal , SURI, Om, Parkash , SURI, Satish, Chander , SOMAL, Preeti , SINGH, Surjit , KHAJURIA, Anamika , GANJOO, Sudesh, Kumar , KUMAR, Arun
IPC分类号： A23L1/06
CPC分类号： A61K36/59 , A23L21/12 , A23L33/105 , A61K36/23 , A61K36/28 , A61K36/53 , A61K36/81 , A61K36/86 , A61K2300/00
摘要： The present invention relates to a novel herbal nutraceutical and more particularly to novel herbal jams andjellies with proven pharmacological activities such as memory enhancer, antioxidant, anti-depressant, immuno-modulator, adapatogen, health promoter and chemically standardized on the basis of one or more bioactive constituents and also to a process for the manufacture of said herbal nutraceuticals.
摘要翻译：本发明涉及一种新颖的草药保健品，更具体地涉及具有证实的药理学活性的新型草药果酱和果冻，例如记忆增强剂，抗氧化剂，抗抑郁剂，免疫调节剂，适应素，健康促进剂，并在一个或多个基础上进行化学标准化生物活性成分，还涉及用于制造所述草药营养食品的方法。

2. 发明申请

WO2004058994A1 PROCESS FOR PREPARATION OF ENZYME ELECTRODE 审中-公开
标题翻译：制备酶电极的方法
公开(公告)号：WO2004058994A1
公开(公告)日：2004-07-15
申请号：PCT/IB2002/005684
申请日：2002-12-31
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
发明人： KUMAR, Arun , RAJESH , MALHOTRA, Bansi, Dhar
IPC分类号： C12Q1/00
CPC分类号： C12Q1/005 , C12Q1/26 , C12Q1/60
摘要： The present invention relates to a process for the preparation of an enzyme electrode by coating an immobilized cholesterol oxidase (ChOx) and mediator on a silicate sol gel by microencapsulation.
摘要翻译：本发明涉及通过微胶囊化在硅酸盐溶胶凝胶上涂布固定化胆固醇氧化酶（ChOx）和介体来制备酶电极的方法。

3. 发明申请

WO2004059310A1 ELECTRODE A ENZYME POUR CHOLESTEROL 审中-公开
标题翻译：电极酶ZOLESOLOL
公开(公告)号：WO2004059310A1
公开(公告)日：2004-07-15
申请号：PCT/IB2002/005680
申请日：2002-12-31
申请人： COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH
发明人： KUMAR, Arun , RAJESH , MALHOTRA, Bansi, Dhar
IPC分类号： G01N27/327
CPC分类号： C12Q1/005 , C12Q1/004
摘要： La présente invention concerne une électrode à enzyme qui convient pour estimer le cholestérol présent dans un milieu aqueux. Cette électrode comprend: (i) une plaque de base électriquement conductrice, (ii) un film ou un matériau dérivé de sol gel déposé sur celle-ci, ce matériau dérivé de sol gel de l'étape (b) étant une cholestérol oxydase micro-encapsulée avec un médiateur d'électron.
摘要翻译： Laprésente发明协调会électrodeà酶i。pour pour pour pour。。。。。。。。。。。。。。。。。。。。。。 Cetteélectrodecomprend：（i）une plaque de baseélectriquementconductrice，（ii）un film ou unmatériaudérivéde sol geldéposésur celle-ci，cematériaudérivéde sol gel de l'étape（b）étantunecholestéroloxydase micro -encapsuléeavec unmédiateurd'électron。

4. 发明申请

WO2011051156A1 SYSTEMS AND METHODS FOR NETWORKING ACROSS WEB BASED AND TELECOMMUNICATION BASED PORTALS 审中-公开
标题翻译：基于WEB和基于电信的门户网络的系统和方法
公开(公告)号：WO2011051156A1
公开(公告)日：2011-05-05
申请号：PCT/EP2010/065850
申请日：2010-10-21
申请人： INTERNATIONAL BUSINESS MACHINES CORPORATION , IBM UNITED KINGDOM LIMITED , KUMAR, Arun , AGARWAL, Sheetal , RAJPUT, Nitendra , NANAVATI, Amit, Anil , DASGUPTA, Koustuv
发明人： KUMAR, Arun , AGARWAL, Sheetal , RAJPUT, Nitendra , NANAVATI, Amit, Anil , DASGUPTA, Koustuv
IPC分类号： H04M3/493
CPC分类号： H04M3/4938 , H04M7/0042 , H04M2203/4527 , H04M2203/655
摘要： A non-web based social networking system enables users having limited Internet connectivity and/or limited access to high end mobile computing devices a cross networking opportunity with web-based social networking sites. Additional communication modalities are defined between social networking users, including but not limited to non-web based communication between the social networking users.
摘要翻译：基于非网络的社交网络系统使得具有有限的因特网连接和/或对高端移动计算设备的访问受限的用户与基于网络的社交网站的交叉联网机会。在社交网络用户之间定义了其他通信模式，包括但不限于社交网络用户之间的非基于Web的通信。

5. 发明申请

WO2010111207A1 COMBINED HEMODYNAMIC AND EGM-BASED ARRHYTHMIA DETECTION 审中-公开
标题翻译：联合HEMODYNAMIC和基于EGM的ARRHYTHMIA检测
公开(公告)号：WO2010111207A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028213
申请日：2010-03-23
申请人： MEDTRONIC, INC. , WHITMAN, Teresa A. , KUMAR, Arun , KLECKNER, Karin J. , GILLBERG, Jeffrey M. , JACKSON, Troy E. , SHRIVASTAV, Maneesh , BROWN, Mark L.
发明人： WHITMAN, Teresa A. , KUMAR, Arun , KLECKNER, Karin J. , GILLBERG, Jeffrey M. , JACKSON, Troy E. , SHRIVASTAV, Maneesh , BROWN, Mark L.
IPC分类号： A61N1/39 , A61B5/0205 , A61B5/046 , A61B5/0464 , A61B5/0215 , A61N1/365
CPC分类号： A61N1/3621 , A61B5/0215 , A61B5/0464 , A61N1/36564 , A61N1/36571 , A61N1/36578
摘要： A medical device for detecting arrhythmias that includes sensing cardiac electrical signals and cardiac hemodynamic signals, determining a long-term baseline hemodynamic measurement in response to a plurality of the sensed cardiac hemodynamic signals, detecting a period of increased metabolic demand in response to the sensed cardiac electrical signals, determining a sinus tachycardia baseline hemodynamic measurement in response to sensing of cardiac hemodynamic signals during the detected period of increased metabolic demand, and detecting the arrhythmia and delivering therapy in response to one of only the sensed cardiac electrical signals and the sensed cardiac electrical signals in combination with one or both of the determined long-term baseline hemodynamic measurement and the sinus tachycardia baseline hemodynamic measurement.
摘要翻译：一种用于检测心律失常的医疗装置，其包括感测心脏电信号和心脏血液动力学信号，响应于多个所感测到的心脏血流动力信号确定长期基线血液动力学测量，响应于感测的心脏检测增加的代谢需求的时期电信号，响应于在增加的代谢需求的检测期间响应于心脏血液动力学信号的感测而确定窦性心动过速基线血液动力学测量，以及响应于仅感测的心电信号和感测到的心脏电信之一检测心律失常并递送治疗信号与确定的长期基线血液动力学测量和窦性心动过速基线血液动力学测量中的一个或两个相结合。

6. 发明申请

WO2007127480A2 MATERIALS AND METHODS TO REDUCE LOW DENSITY LIPOPROTEIN CHOLESTEROL 审中-公开
标题翻译：减少低密度脂蛋白胆固醇的材料和方法
公开(公告)号：WO2007127480A2
公开(公告)日：2007-11-08
申请号：PCT/US2007/010496
申请日：2007-04-30
申请人： UNIVERSITY OF SOUTH FLORIDA , MOHAPATRA, Shyam, S. , KUMAR, Arun
发明人： MOHAPATRA, Shyam, S. , KUMAR, Arun
IPC分类号： A61F2/02
CPC分类号： A61K9/5146 , A61K9/5161 , Y10S977/739 , Y10S977/746 , Y10S977/747 , Y10S977/90
摘要： The present invention pertains to nanoparticles, comprising a metal and/or polymer core, with 7-alpha hydroxylase, or an enzymatically active fragment thereof, nicotinamide adenine dinucleotide (NADH) and antibodies, or antibody fragments, specific for low density lipoprotein (LDL), attached to the core. The invention also concerns methods for reducing LDL cholesterol in a human or animal subject by administering nanoparticles of the invention. In a preferred embodiment, both circulating LDL and plasma cholesterol levels are reduced in the subject.
摘要翻译：本发明涉及包含具有7-α羟化酶或其酶活性片段，特异于低密度脂蛋白（LDL）的烟酰胺腺嘌呤二核苷酸（NADH）和抗体或抗体片段的金属和/或聚合物核心的纳米颗粒，，附在核心。本发明还涉及通过施用本发明的纳米颗粒来降低人或动物受试者中的LDL胆固醇的方法。在优选的实施方案中，受试者中循环LDL和血浆胆固醇水平都降低。

7. 发明申请

WO2013010083A2 FAILURE DETECTION SYSTEM FOR PHOTOVOLTAIC ARRAY 审中-公开
标题翻译：光伏阵列故障检测系统
公开(公告)号：WO2013010083A2
公开(公告)日：2013-01-17
申请号：PCT/US2012/046678
申请日：2012-07-13
申请人： UNITED SOLAR OVONIC LLC , KUMAR, Arun
发明人： KUMAR, Arun
IPC分类号： G01R31/36 , G01R19/00
CPC分类号： H02S50/10
摘要： A process for detecting and terminating a fault in a photovoltaic device is provided that operates in the millisecond or faster timescale. A process includes measuring a current or voltage in each of a plurality of strings relative to a common rail. When the voltage or current from a string is outside a predetermined threshold, a flag is generated indicating the presence of a fault in the string. A control unit will detect the flag and disconnect the faulty string from the system through a switch. The use of continuously rolling averages of baseline currents and voltages as well as a series of measurements averaged to measure the difference of current or voltage at each step provides a process and a fault detection system that does not suffer from false fault detections thereby providing a reliable and efficient system for detecting and terminating faults in photovoltaic devices.
摘要翻译：提供了一种用于检测和终止光伏设备中的故障的过程，其以毫秒或更快的时间刻度运行。过程包括测量多个串中的每一个中的电流或电压相对于共轨。当来自串的电压或电流超出预定阈值时，将产生标志，指示串中存在故障。控制单元将检测标志并通过开关从系统断开故障串。使用基线电流和电压的连续滚动平均值以及平均的一系列测量结果来测量每个步骤处的电流或电压差异提供了不会受到错误故障检测的过程和故障检测系统，从而提供可靠的以及用于检测和终止光伏设备故障的高效系统。

8. 发明申请

WO2012015499A1 PATASYMPATHETIC STIMULATION TO ENHANCE TACHYARRHYTHMIA DETECTION 审中-公开
标题翻译：加速TACHYARRHYTHMIA检测的动态曲线刺激
公开(公告)号：WO2012015499A1
公开(公告)日：2012-02-02
申请号：PCT/US2011/033566
申请日：2011-04-22
申请人： MEDTRONIC, INC. , KUMAR, Arun , MUSLEY, Shailesh Kumar, Vishnu
发明人： KUMAR, Arun , MUSLEY, Shailesh Kumar, Vishnu
IPC分类号： A61N1/36 , A61B5/0464 , A61B5/0456
CPC分类号： A61N1/36585 , A61N1/36114 , A61N1/3962
摘要： This disclosure is directed toward techniques for classifying a tachycardia as supraventricular tachycardia or ventricular tachycardia. A method comprises detecting a tachycardia based on at least one value of a cardiac interval, delivering vagal stimulation in response to the detection of the tachycardia, sensing a physiological parameter other than the cardiac interval during or subsequent to delivering the vagal stimulation, and classifying the tachycardia as supraventricular or ventricular based on the sensed physiological parameter. In some examples, the method includes sensing a response of a physiological parameter other than cardiac rate to the vagal stimulation, such as pressure or a morphological characteristic of the cardiac electrical waveform. The method may include providing an indication to a user based on the classification of supraventricular tachycardia, or delivery of appropriate electrical therapy based on the classification of ventricular tachycardia or ventricular fibrillation.
摘要翻译：本公开涉及将心动过速分类为室上性心动过速或室性心动过速的技术。一种方法包括基于心脏间隔的至少一个值检测心动过速，响应于心动过速的检测传递迷走神经刺激，感测在输送迷走神经刺激期间或之后的心脏间隔以外的生理参数，并分类基于感觉到的生理参数，作为室上性或室性心动过速。在一些示例中，该方法包括感测除了心率之外的生理参数对迷走神经刺激的响应，例如心电波形的压力或形态特征。该方法可以包括基于室上性心动过速的分类或基于室性心动过速或心室纤维性颤动的分类递送适当的电疗法来向使用者提供指示。

9. 发明申请

WO2011068874A3 DRUG DELIVERY DEVICE FOR OVARIAN CANCER 审中-公开
公开(公告)号：WO2011068874A3
公开(公告)日：2011-06-09
申请号：PCT/US2010/058565
申请日：2010-12-01
申请人： UNIVERSITY OF SOUTH FLORIDA , KUMAR, Arun , LAI-YUEN, Susana, K. , MOHAPATRA, Shyam, S. , PARSONS, Anna K.
发明人： KUMAR, Arun , LAI-YUEN, Susana, K. , PARSONS, Anna K.
IPC分类号： A61M31/00 , A61M37/00 , A61M5/14 , A61B17/42
摘要： A drug delivery device has been designed to directly deliver an agent to the ovaries through direct contact with the fallopian tubes. The device consists of three main components: a tubular inserter, a cylindrical chamber and a plunger. The device is a single-use applicator designed in a shape similar to a tampon to facilitate its insertion through the vagina and into the uterus. Positioning of the device centrally in the uterus is accomplished through the use of ultrasound. The chamber is inserted into the tubular inserter. Adjusting the length of the chamber inserted into the tubular inserter controls the amount of tubing released from the apertures in the tubular inserter. Ultrasound is used to ensure the proper placement of each tube at the entrance of each fallopian tube. The plunger is inserted into the chamber and adjustment of the plunger controls the amount of the agent released into the tubes.

10. 发明申请

WO2008048272A2 METHOD OF DRUG DELIVERY BY CARBON NANOTUBE-CHITOSAN NANOCOMPLEXES 审中-公开
标题翻译：通过碳纳米管 - 壳聚糖纳米复合物递送药物的方法
公开(公告)号：WO2008048272A2
公开(公告)日：2008-04-24
申请号：PCT/US2006/041570
申请日：2006-10-23
申请人： UNIVERSITY OF SOUTH FLORIDA , MOHAPATRA, Shyam, S. , KUMAR, Arun
发明人： MOHAPATRA, Shyam, S. , KUMAR, Arun
IPC分类号： A61K48/00
CPC分类号： A61K48/0041
摘要： Functionalized Single Wall Carbon Nanotube (SWCNT) complexed with nanochitosan for use in the delivery of bioaffecting substances and diagnostic applications. fSWCNT complexed with the chitosan NG042 were used for delivery of DNA-encoding EGFP reporter protein and peptide. The results demonstrate that shown CNT-chitosan hybrid nanoparticles exhibit significantly higher transfection efficiency in vivo than chitosan alone. Furthermore, the functionalized nanotubes were tested for peptide transfer into HEK293 cells. The results showed that the hybrid nanoparticles efficiently transferred peptides. Together, these results show that hybrid SWCNT-chitosan particles increase DNA and peptide transfer into cells.
摘要翻译：与纳米壳聚糖复合的功能化单壁碳纳米管（SWCNT）用于递送生物影响物质和诊断应用。与壳聚糖NG042复合的fSWCNT用于递送编码DNA的EGFP报道蛋白和肽。结果表明，所示的CNT-壳聚糖杂化纳米颗粒在体内的转染效率显着高于单独的壳聚糖。此外，功能化的纳米管被测试以将肽转移到HEK293细胞中。结果显示混合纳米颗粒有效地转移肽。总之，这些结果表明杂交SWCNT-壳聚糖颗粒增加DNA和肽转移到细胞中。

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