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1. 发明申请

WO2011139686A1 METHOD AND APPARATUS FOR DETECTING AND DISCRIMINATING TACHYCARDIA 审中-公开
标题翻译：用于检测和鉴定TACHYCARDIA的方法和装置
公开(公告)号：WO2011139686A1
公开(公告)日：2011-11-10
申请号：PCT/US2011/033933
申请日：2011-04-26
申请人： MEDTRONIC, INC. , ZHANG, Xusheng , STADLER, Robert, W. , GREENHUT, Saul, E. , BROWN, Mark, L. , JACKSON, Troy, E. , WHITMAN, Teresa, A.
发明人： ZHANG, Xusheng , STADLER, Robert, W. , GREENHUT, Saul, E. , BROWN, Mark, L. , JACKSON, Troy, E. , WHITMAN, Teresa, A.
IPC分类号： A61B5/0452 , A61N1/39 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61N1/362
CPC分类号： A61B5/0452 , A61B5/04525 , A61B5/046 , A61B5/0464 , A61B5/0472 , A61B5/7203 , A61N1/3621
摘要： A medical device and associated method obtaining cardiac event intervals corresponding to a tachycardia interval. Evidence of a rhythm breaking point is obtained in response to sensing a cardiac event having a morphology corresponding to a supraventricular beat. A non-treatable rhythm is detected in response to the plurality of cardiac event intervals and the evidence of the rhythm breaking point.
摘要翻译：获得对应于心动过速间隔的心脏事件间隔的医疗装置和相关方法。响应于感测具有对应于室上搏动的形态的心脏事件而获得节律断点的证据。响应于多个心脏事件间隔和节律断点的证据来检测不可治疗的节律。

2. 发明申请

WO2006081376A1 SYSTEM AND METHOD FOR DETECTING ARTIFACTUAL HEMODYNAMIC WAVEFORM DATA 审中-公开
标题翻译：用于检测人造血液波形数据的系统和方法
公开(公告)号：WO2006081376A1
公开(公告)日：2006-08-03
申请号：PCT/US2006/002829
申请日：2006-01-26
申请人： MEDTRONIC, INC. , CHOI, Mark , IGEL, David, A. , BENNETT, Tommy, D. , HILL, Michael, R., S. , WHITMAN, Teresa, A.
发明人： CHOI, Mark , IGEL, David, A. , BENNETT, Tommy, D. , HILL, Michael, R., S. , WHITMAN, Teresa, A.
IPC分类号： A61B5/0215
CPC分类号： A61B5/0215 , A61B5/02108
摘要： A system and method for cardiovascular analysis includes an implantable medical device capable of generating hemodynamic pressure waveform data based upon sensed pressure. Hemodynamic waveform data is analyzed to identify artifactual data represented in the hemodynamic waveform.
摘要翻译：用于心血管分析的系统和方法包括能够基于检测到的压力产生血流动力压力波形数据的可植入医疗装置。分析血流动力学波形数据以识别在血流动力学波形中表示的人为因素数据。

3. 发明申请

WO2006060704A1 USE OF MECHANICAL RESTITUTION TO PREDICT HEMODYNAMIC RESPONSE TO A RAPID VENTRICULAR RHYTHM 审中-公开
标题翻译：使用机械分辨预测对快速心室节律的血流动力学反应
公开(公告)号：WO2006060704A1
公开(公告)日：2006-06-08
申请号：PCT/US2005/043717
申请日：2005-12-05
申请人： MEDTRONIC, INC. , WHITMAN, Teresa, A.
发明人： WHITMAN, Teresa, A.
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/3622
摘要： An implantable cardiac stimulation device and associated method for predicting the hemodynamic response to a rapid heart rhythm. The system includes an implantable cardiac stimulation device and associated sensors of electrical and mechanical heart function. The associated method includes measuring a mechanical restitution (MR) parameter or surrogate thereof, performing a comparative analysis of the MR parameter, and predicting an unstable or stable hemodynamic response to a rapid heart rate based on the comparative analysis. If an unstable hemodynamic response to a rapid rhythm is predicted, a more aggressive menu of arrhythmia therapies may be programmed to treat tachycardia. If a stable hemodynamic response is predicted, a less aggressive menu of therapies may be programmed to treat tachycardia.
摘要翻译：用于预测对快速心律的血液动力学响应的可植入心脏刺激装置和相关方法。该系统包括可植入的心脏刺激装置以及电和机械心脏功能的相关传感器。相关联的方法包括测量机械恢复（MR）参数或其替代物，执行MR参数的比较分析，并基于比较分析预测对快速心率的不稳定或稳定的血液动力响应。如果预测到对快速节律的不稳定血流动力学反应，则可以编程更加积极的心律失常治疗菜单来治疗心动过速。如果预测到稳定的血液动力学反应，则可以编程一个较不积极的疗法菜单来治疗心动过速。

4. 发明申请

WO2010111209A1 COMBINED HEMODYNAMIC AND EGM-BASED ARRHYTHMIA DETECTION 审中-公开
标题翻译：联合HEMODYNAMIC和基于EGM的ARRHYTHMIA检测
公开(公告)号：WO2010111209A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028217
申请日：2010-03-23
申请人： MEDTRONIC, INC. , WHITMAN, Teresa, A. , KUMAR, Arun , KLECKNER, Karin, J. , GILLBERG, Jeffrey, M. , JACKSON, Troy, E. , SHRIVASTAV, Maneesh , BROWN, Mark, L.
发明人： WHITMAN, Teresa, A. , KUMAR, Arun , KLECKNER, Karin, J. , GILLBERG, Jeffrey, M. , JACKSON, Troy, E. , SHRIVASTAV, Maneesh , BROWN, Mark, L.
IPC分类号： A61N1/39 , A61B5/0205 , A61B5/046 , A61B5/0464 , A61N1/365
CPC分类号： A61N1/3621 , A61B5/0215 , A61B5/0464 , A61N1/36564 , A61N1/36571 , A61N1/36578
摘要： A medical device for detecting arrhythmias that includes electrodes for sensing cardiac electrical signals and a hemodynamic sensor for sensing a hemodynamic signal. An episode of cardiac electrical event intervals meeting cardiac arrhythmia detection criteria is detected from the sensed electrical signals. Cardiac mechanical events and/or cardiac mechanical event intervals are measured from the hemodynamic signal and used to withhold or confirm a cardiac arrhythmia detection of the episode.
摘要翻译：一种用于检测心律失常的医疗装置，其包括用于感测心脏电信号的电极和用于感测血液动力学信号的血液动力学传感器。从感测到的电信号中检测到满足心律失常检测标准的心脏电活动间隔的发作。从血液动力学信号测量心脏机械事件和/或心脏机械事件间隔，并用于抑制或确认发作的心律失常检测。

5. 发明申请

WO2006060704A9 USE OF MECHANICAL RESTITUTION TO PREDICT HEMODYNAMIC RESPONSE TO A RAPID VENTRICULAR RHYTHM 审中-公开
标题翻译：机械衰退对预测快速反应的HEMODYNAMIC反应的使用
公开(公告)号：WO2006060704A9
公开(公告)日：2006-07-06
申请号：PCT/US2005043717
申请日：2005-12-05
申请人： MEDTRONIC INC , WHITMAN TERESA A
发明人： WHITMAN TERESA A
IPC分类号： A61N1/362
CPC分类号： A61N1/3627 , A61N1/3622
摘要： An implantable cardiac stimulation device and associated method for predicting the hemodynamic response to a rapid heart rhythm. The system includes an implantable cardiac stimulation device and associated sensors of electrical and mechanical heart function. The associated method includes measuring a mechanical restitution (MR) parameter or surrogate thereof, performing a comparative analysis of the MR parameter, and predicting an unstable or stable hemodynamic response to a rapid heart rate based on the comparative analysis. If an unstable hemodynamic response to a rapid rhythm is predicted, a more aggressive menu of arrhythmia therapies may be programmed to treat tachycardia. If a stable hemodynamic response is predicted, a less aggressive menu of therapies may be programmed to treat tachycardia.
摘要翻译：一种植入式心脏刺激装置及相关方法，用于预测快速心律的血流动力学反应。该系统包括可植入心脏刺激装置和相关联的电气和机械心脏功能传感器。相关方法包括测量机械恢复（MR）参数或其替代物，进行MR参数的比较分析，并且基于比较分析预测对快速心率的不稳定或稳定的血液动力学响应。如果预测到对快速节律的不稳定的血液动力学反应，则可以编程更积极的心律失常疗法菜单来治疗心动过速。如果预测出稳定的血液动力学反应，可以编程较不积极的疗法菜单来治疗心动过速。

6. 发明申请

WO2005072817A1 IMPLANTABLE LEAD INCLUDING SENSOR 审中-公开
标题翻译：可插入导线，包括传感器
公开(公告)号：WO2005072817A1
公开(公告)日：2005-08-11
申请号：PCT/US2005/001033
申请日：2005-01-12
申请人： MEDTRONIC, INC. , MARSHALL, Mark, T. , MCHENRY, Brian, T. , WHITMAN, Teresa, A. , VIKTORA, Sandra, F.
发明人： MARSHALL, Mark, T. , MCHENRY, Brian, T. , WHITMAN, Teresa, A. , VIKTORA, Sandra, F.
IPC分类号： A61N1/05
CPC分类号： A61B5/0215 , A61N1/056
摘要： An implantable medical lead includes an adaptor coupled to a body of the lead. The adaptor holds a sensor capsule between a first portion and a second portion of the lead body.
摘要翻译：可植入医疗引线包括耦合到引线主体的适配器。适配器将传感器囊保持在引线主体的第一部分和第二部分之间。

7. 发明申请

WO2004103470B1 MEDICAL SYSTEM INCLUDING A NOVEL BIPOLAR PACING PAIR 审中-公开
标题翻译：医疗系统包括一个新的双极板对
公开(公告)号：WO2004103470B1
公开(公告)日：2005-06-02
申请号：PCT/US2004015152
申请日：2004-05-13
申请人： MEDTRONIC INC , BROWN MARK L , WARMAN EDUARDO N , GILLBERG JEFFREY M , BONNER MATTHEW D , MARSHALL MARK T , WHITMAN TERESA A
发明人： BROWN MARK L , WARMAN EDUARDO N , GILLBERG JEFFREY M , BONNER MATTHEW D , MARSHALL MARK T , WHITMAN TERESA A
IPC分类号： A61N1/05 , A61N1/368 , A61N1/37 , A61N1/39 , A61N1/00
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0573 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pair for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.
摘要翻译：可植入电气医疗系统包括低压阴极电极组件，其包括适于与电活性组织紧密接触的阴极表面，以及包括阳极表面和在阳极表面上延伸的多孔层的低压阳极电极组件。阴极表面和阳极表面用作用于起搏的双极对，并且在阳极表面上延伸的多孔层允许通过其传导，并且防止阳极表面接触电活性组织以防止阳极刺激。

8. 发明申请

WO2004103470A1 MEDICAL SYSTEM INCLUDING A NOVEL BIPOLAR PACING PAIR 审中-公开
标题翻译：医疗系统包括一个新的双极板对
公开(公告)号：WO2004103470A1
公开(公告)日：2004-12-02
申请号：PCT/US2004/015152
申请日：2004-05-13
申请人： MEDTRONIC, INC. , BROWN, Mark, L. , WARMAN, Eduardo, N. , GILLBERG, Jeffrey, M. , BONNER, Matthew, D. , MARSHALL, Mark, T. , WHITMAN, Teresa, A.
发明人： BROWN, Mark, L. , WARMAN, Eduardo, N. , GILLBERG, Jeffrey, M. , BONNER, Matthew, D. , MARSHALL, Mark, T. , WHITMAN, Teresa, A.
IPC分类号： A61N1/39
CPC分类号： A61N1/057 , A61N1/0568 , A61N1/0573 , A61N1/368 , A61N1/3702 , A61N2001/0585
摘要： An implantable electrical medical system comprises a low voltage cathode electrode assembly, including a cathode surface adapted for intimate contact with electrically active tissue, and a low voltage anode electrode assembly, including an anode surface and a porous layer extending over the anode surface. The cathode surface and the anode surface function as a bipolar pair for pacing and the porous layer extending over the anode surface allows conduction therethrough and prevents the anode surface from contacting the electrically active tissue in order to prevent anodal stimulation.
摘要翻译：可植入电气医疗系统包括低压阴极电极组件，其包括适于与电活性组织紧密接触的阴极表面，以及包括阳极表面和在阳极表面上延伸的多孔层的低压阳极电极组件。阴极表面和阳极表面用作用于起搏的双极对，并且在阳极表面上延伸的多孔层允许通过其传导，并且防止阳极表面接触电活性组织以防止阳极刺激。

9. 发明申请

WO2016123532A1 NONINVASIVE ASSESSMENT OF CARDIAC RESYNCHRONIZATION THERAPY 审中-公开
标题翻译：心脏再生治疗无效评估
公开(公告)号：WO2016123532A1
公开(公告)日：2016-08-04
申请号：PCT/US2016/015738
申请日：2016-01-29
申请人： MEDTRONIC, INC. , STADLER, Robert W. , STEGEMANN, Berthold , CORNELUSSEN, Richard , GHOSH, Subham , CHO, Yong K. , GILLBERG, Jeffrey M. , WHITMAN, Teresa A.
IPC分类号： A61B5/11 , A61B5/0472 , A61B5/00 , A61B5/0428 , A61N7/00 , A61N1/368
CPC分类号： A61N7/00 , A61B5/0053 , A61B5/04085 , A61B5/04286 , A61B5/0472 , A61B5/1107 , A61B5/4848 , A61B5/743 , A61B2505/05 , A61N1/362 , A61N1/3627 , A61N7/02 , A61N2007/0004 , A61N2007/0026 , A61N2007/0056
摘要： Systems, methods, and interfaces are described herein for noninvasively determining whether a patient can benefit from cardiac resynchronization therapy. One exemplary method involves delivering ultrasonic energy to cardiac tissue. In response to delivering ultrasonic energy to the cardiac tissue, receiving, with a processing unit, a torso-surface potential signal from each of a plurality of electrodes distributed on a torso of a patient. For at least a subset of the plurality of electrodes, calculating, with the processing unit, a torso-surface activation time based on the signal sensed from the electrode. Presenting, by the processing unit, to a user, an indication of a degree of dyssynchrony of the torso-surface activation times via a display.
摘要翻译：本文描述了系统，方法和界面，用于非侵入性地确定患者是否可以从心脏再同步治疗中受益。一种示例性方法涉及将超声能量递送到心脏组织。响应于向心脏组织递送超声能量，用处理单元接收分布在患者躯干上的多个电极中的每一个的躯干表面电位信号。对于多个电极的至少一个子集，基于从电极感测的信号，利用处理单元计算躯干表面激活时间。由处理单元向用户呈现经由显示器的躯干表面激活时间的不同步程度的指示。

10. 发明申请

WO2010111207A1 COMBINED HEMODYNAMIC AND EGM-BASED ARRHYTHMIA DETECTION 审中-公开
标题翻译：联合HEMODYNAMIC和基于EGM的ARRHYTHMIA检测
公开(公告)号：WO2010111207A1
公开(公告)日：2010-09-30
申请号：PCT/US2010/028213
申请日：2010-03-23
申请人： MEDTRONIC, INC. , WHITMAN, Teresa A. , KUMAR, Arun , KLECKNER, Karin J. , GILLBERG, Jeffrey M. , JACKSON, Troy E. , SHRIVASTAV, Maneesh , BROWN, Mark L.
发明人： WHITMAN, Teresa A. , KUMAR, Arun , KLECKNER, Karin J. , GILLBERG, Jeffrey M. , JACKSON, Troy E. , SHRIVASTAV, Maneesh , BROWN, Mark L.
IPC分类号： A61N1/39 , A61B5/0205 , A61B5/046 , A61B5/0464 , A61B5/0215 , A61N1/365
CPC分类号： A61N1/3621 , A61B5/0215 , A61B5/0464 , A61N1/36564 , A61N1/36571 , A61N1/36578
摘要： A medical device for detecting arrhythmias that includes sensing cardiac electrical signals and cardiac hemodynamic signals, determining a long-term baseline hemodynamic measurement in response to a plurality of the sensed cardiac hemodynamic signals, detecting a period of increased metabolic demand in response to the sensed cardiac electrical signals, determining a sinus tachycardia baseline hemodynamic measurement in response to sensing of cardiac hemodynamic signals during the detected period of increased metabolic demand, and detecting the arrhythmia and delivering therapy in response to one of only the sensed cardiac electrical signals and the sensed cardiac electrical signals in combination with one or both of the determined long-term baseline hemodynamic measurement and the sinus tachycardia baseline hemodynamic measurement.
摘要翻译：一种用于检测心律失常的医疗装置，其包括感测心脏电信号和心脏血液动力学信号，响应于多个所感测到的心脏血流动力信号确定长期基线血液动力学测量，响应于感测的心脏检测增加的代谢需求的时期电信号，响应于在增加的代谢需求的检测期间响应于心脏血液动力学信号的感测而确定窦性心动过速基线血液动力学测量，以及响应于仅感测的心电信号和感测到的心脏电信之一检测心律失常并递送治疗信号与确定的长期基线血液动力学测量和窦性心动过速基线血液动力学测量中的一个或两个相结合。

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