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1. 发明申请

WO2008090066A2 STABILIZATION OF UV-SENSITIVE ACTIVE INGREDIENTS 审中-公开
标题翻译：紫外线敏感活性成分的稳定性
公开(公告)号：WO2008090066A2
公开(公告)日：2008-07-31
申请号：PCT/EP2008/050440
申请日：2008-01-16
申请人： CIBA HOLDING INC. , WAGNER, Barbara , HERZOG, Bernd , MÜLLER, Stefan , EHLIS, Thomas
发明人： WAGNER, Barbara , HERZOG, Bernd , MÜLLER, Stefan , EHLIS, Thomas
IPC分类号： A61K8/41 , A61K8/44 , A61K8/49 , A61Q17/04
CPC分类号： A61K8/41 , A61K8/35 , A61K8/44 , A61K2800/52 , A61Q5/00 , A61Q5/02 , A61Q5/04 , A61Q5/06 , A61Q5/12 , A61Q17/04 , A61Q19/004 , A61Q19/04
摘要： Disclosed is the use of merocyanine derivatives of formula (1) for stabilizing UV-sensitive active ingredients like dibenzoylmethane derivatives.
摘要翻译：公开了式（1）的部花青衍生物用于稳定紫外线敏感活性成分如二苯甲酰甲烷衍生物的用途。

2. 发明申请

WO2006003094A2 MEROCYANINE DERIVATIVES 审中-公开
公开(公告)号：WO2006003094A2
公开(公告)日：2006-01-12
申请号：PCT/EP2005/052850
申请日：2005-06-20
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , WAGNER, Barbara , BIENEWALD, Frank , WOLLEB, Heinz , WALLQUIST, Olof , HERZOG, Bernd , EHLIS, Thomas , HAASE, Jürg
发明人： WAGNER, Barbara , BIENEWALD, Frank , WOLLEB, Heinz , WALLQUIST, Olof , HERZOG, Bernd , EHLIS, Thomas , HAASE, Jürg
IPC分类号： A61K7/42
CPC分类号： A61K8/498 , A61K8/4913 , A61K8/494 , A61Q17/04
摘要： Disclosed is the use of merocyanine derivatives of formula (I), wherein Q is hydrogen; C 1 -C 22 alkyl; -OH; -OR 7 ; -NR 7 R 8 ; or -N=R 9 ; R 1 is hydrogen; C 1 -C 22 alkyl; -OR 7 , -SR 7 ; -NR 7 R 8 ; C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; C 7 -C 12 aralkyl; C 1 -C 12 heteroalkyl, C 2 -C 11 heteroaralkyl; C 6 -C 10 aryl; or C 1 -C 9 heteroaryl; R 4 is cyano; COR 7 , COOR 7 ; CONR 7 R 8 ; SO 2 (C 6 -C 12 )aryl; C 2 -C 12 alk-1-enyl; C 3 -C 12 cycloalk-1-enyl; C 2 -C 12 alk-1-inyl; C 2 -C 12 heteroalkyl; C 3 -C 5 heterocycloalkyl; C 6 -C 10 aryl; or C 1 -C 9 heteroaryl; R 5 is -COR 7 ; -COOR 7 ; -OR 7 ; -SR 7 , -NHR 7 , -NR 7 R 8 ; C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; C 7 -C 12 aralkyl; C 1 -C 12 alkylphenyl; C 1 -C 12 alkoxy-C 6 -C 10 aryl; C 1 -C 12 heteroalkyl; C 2 -C 11 heteroaralkyl; C 3 -C 12 cycloheteroalkyl; C 6 -C 10 aryl; C 1 - C 12 alkoxy-C 6 -C 10 aryl; or C 1 -C 9 heteroaryl; R 6 is hydrogen; C 1 -C 22 alkyl; C 1 -C 22 alkoxy; or COR 7 ; R 7 and R 8 independently from each other are hydrogen; C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl; C 3 -C 12 cycloalkenyl; -(CH 2 ) t COOH; C 7 -C 12 aralkyl; C 1 -C 12 heteroalkyl; C 2 -C 11 heteroaralkyl; C 6 -C 10 aryl; C 1 -C 9 heteroaryl; Si-R 10 R 11 R 12 ; Si(OR 10 )(OR 11 )(OR 12 ); SiR 10 (OR 11 )(OR 12 ); SiR 10 R 11 (OR 12 ); -(CH 2 ) u -O-(CH 2 ) v -SiR 10 R 11 R 12 ; or a radical X-Sil; t, u and v, independently from each other are a number from 1 to 5; R 9 is a (C 1 -C 6 )alkylidene radical; R 10 , R 11 , R 12 independently form each other are C 1 -C 22 alkyl; X is a linker; Sil is a silane-, oligosiloxane- or polysiloxane radical; R 1 and R 2 , R 1 and Q, R 1 and R 6 , R 1 and T, R 2 and R 3 , R 2 and R 4 , R 2 and R 6 , R 2 and Q, R 4 and R 6 , R 4 and T, R 6 and Q, T and Q, each independently, are linked together, so that 1, 2, 3 or 4 carbocyclic or N, O and/or S-heterocyclic rings are formed, wherein each of them, independently from each other, may be condensed with an aromatic or heteroaromatic ring, and/or more N-, O- and/or S-heterocyclic rings, and each N atom in a N-heterocyclic ring may be substituted by C 1 -C 22 alkyl; n is a number from 1 to 4; wherein at least one of the radicals R 1 , R 6 or Q is different from hydrogen; if n = 1 T is -COR 5 ; -CN; C 6 -C 10 aryl; -NHR 5 ; or -SO 2 -(C 6 -C 12 )aryl; R 2 and R 3 independently from each other are C 1 -C 22 alkyl; hydroxy-C 1 -C 22 alkyl; C 2 -C 12 alkenyl; C 2 -C 12 alkinyl; C 3 -C 12 cycloalkyl, C 3 -C 12 cycloalkenyl; C 7 -C 12 aralkyl; C 1 -C 12 heteroalkyl; C 3 -C 12 cycloheteroalkyl; C 6 -C 10 aryl; C 1 -C 9 heteroaryl; or a radical of formula (II); p is a number from 5 to 100; q is a number from 1 to 5; s is a number from 0 to 4; if n = 2 R 2 and R 3 are each C 1 -C 5 alkylene; and simultaneously T is defined as for n = 1; or T is a bivalent radical of formula -NR 7 -V-NR 7 -, wherin V is phenylene; or C 1 -C 5 alkylene; R 7 is hydrogen; or C 1 -C 5 alkyl; and R 2 and R 3 simultaneously are defined as for n = 1; if n = 3 one of R 2 , R 3 or T is a trivalent radical; if n = 4 one of R 2 , R 3 or T is a tetravalent radical; for protecting of human hair and skin against the damaging effect of UV radiation.

3. 发明申请

WO2010136360A2 BENZYLIDENE MALONATES 审中-公开
标题翻译：苯并噻唑啉酮
公开(公告)号：WO2010136360A2
公开(公告)日：2010-12-02
申请号：PCT/EP2010/056843
申请日：2010-05-19
申请人： BASF SE , HANSCH, Markus , EHLIS, Thomas , WALLQUIST, Olof , WAGNER, Barbara , HERZOG, Bernd , GIESINGER, Jochen
发明人： HANSCH, Markus , EHLIS, Thomas , WALLQUIST, Olof , WAGNER, Barbara , HERZOG, Bernd , GIESINGER, Jochen
IPC分类号： A61K8/37 , A61Q17/04 , C07C69/73
CPC分类号： A61K8/37 , A61Q17/04 , C07C69/73
摘要： Disclosed is the use of benzylidene malonates of formula (1), wherein R 1 is methyl; ethyl; propyl; or n-butyl; if R 1 is methyl, then R is tert. butyl; formula (A); a radical of formula (1a); or a radical of formula (1b); wherein R 2 and R 3 , independently from each other are hydrogen; or methyl; R 4 is methyl; ethyl; or n-propyl; R 5 and R 6 independently from each other are hydrogen; or C 1 -C 3 alkyl; if R 1 is ethyl; propyl; or n-butyl, then R is isopropyl; for the protection of human and animal hair and skin against UV radiation.
摘要翻译：公开了式（1）的亚苄基丙二酸酯的用途，其中R 1是甲基; 乙基; 丙基; 或正丁基; 如果R1是甲基，那么R是叔丁基。丁基; 式（A）; 式（1a）的基团; 或式（1b）的基团; 其中R2和R3彼此独立地是氢; 或甲基; R4是甲基; 乙基; 或正丙基; R5和R6彼此独立地是氢; 或C 1 -C 3烷基; 如果R1是乙基; 丙基; 或正丁基，那么R是异丙基; 用于保护人和动物的头发和皮肤免受紫外线辐射。

4. 发明申请

WO2008110465A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS 审中-公开
标题翻译：类似氧化物的抗氧化剂和紫外线吸收剂
公开(公告)号：WO2008110465A1
公开(公告)日：2008-09-18
申请号：PCT/EP2008/052463
申请日：2008-02-29
申请人： CIBA HOLDING INC. , WAGNER, Barbara , MONGIAT, Sébastien , HERZOG, Bernd , BASCHONG, Werner , BUTHE, Andreas , ÖHRLEIN, Reinhold
发明人： WAGNER, Barbara , MONGIAT, Sébastien , HERZOG, Bernd , BASCHONG, Werner , BUTHE, Andreas , ÖHRLEIN, Reinhold
IPC分类号： A61Q17/04
CPC分类号： C07D493/04 , A61K8/4973 , A61K8/498 , A61K2800/522 , A61Q17/04 , C07D491/04
摘要： The present invention relates toderivatives of the 1H-pyrano[4,3-b]benzofuran-1-one structure and their nitrogen analogueswhichpossess powerful antioxidant properties combined with a highly effective UV absorbing functionality in one molecule.These compounds are especially useful in cosmetical and dermatological formulations.
摘要翻译：本发明涉及1H-吡喃并[4,3-b]苯并呋喃-1-酮结构的衍生物及其具有强大抗氧化性能的氮类似物，其与一个分子中的高效紫外吸收功能相结合。这些化合物特别适用于化妆品和皮肤科配方。

5. 发明申请

WO2009007264A2 WATER BASED CONCENTRATED PRODUCT FORMS OF OIL-SOLUBLE ORGANIC UV ABSORBERS 审中-公开
标题翻译：水溶性有机紫外线吸收剂的浓缩产品形式
公开(公告)号：WO2009007264A2
公开(公告)日：2009-01-15
申请号：PCT/EP2008/058356
申请日：2008-06-30
申请人： CIBA HOLDING INC. , MÜLLER, Stefan , LINDEMANN, Brigitte , HERZOG, Bernd
发明人： MÜLLER, Stefan , LINDEMANN, Brigitte , HERZOG, Bernd
IPC分类号： A61K8/11 , A61K8/35 , A61K8/37 , A61K8/44 , A61K8/49 , A61K8/81 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/11 , A61K8/35 , A61K8/37 , A61K8/44 , A61K8/445 , A61K8/496 , A61K8/4966 , A61K8/585 , A61K8/8152 , A61K8/893 , A61K2800/413
摘要： The instant invention refers to the use of a concentrated aqueous polymer dispersion with an average particle size of less than 1000 nm comprising (a) a polymer carrier prepared by heterophase radical polymerization of at least one ethylenically unsaturated monomer in the presence of (b) an oil-soluble organic UV absorber selected from the class of p-aminobenzoic acid derivatives; salicylic acid derivatives; benzophenone derivatives; diphenyl acrylate derivatives; benzofuran derivatives; polymeric UV absorbers, comprising one or more organosilicon radicals; cinnamic acid derivatives; camphor derivatives; s-triazine derivatives; trianilino-s-triazine derivatives; menthyl anthranilates; and benzotriazole derivatives; wherein the weight ratio of the oil-soluble organic UV absorber (b) to polymer carrier (a) is greater than 50 parts UV absorber per 100 parts of carrier; for the protection of human and animal hair and skin against the damaging effect of UV radiation. The concentrated aqueous polymer dispersions show unexpectedly high sunscreen effects and a positive skin feeling.
摘要翻译：本发明涉及使用平均粒度小于1000nm的浓聚合物水分散体分散体，其包含（a）通过至少一种烯键式不饱和单体的异相自由基聚合制备的聚合物载体在（b）选自对氨基苯甲酸衍生物类的油溶性有机UV吸收剂存在下; 水杨酸衍生物; 二苯甲酮衍生物; 丙烯酸二苯酯衍生物; 苯并呋喃衍生物; 包含一个或多个有机硅基团的聚合物UV吸收剂; 肉桂酸衍生物; 樟脑衍生物; 均三嗪衍生物; 三苯胺基-s-三嗪衍生物; 邻氨基苯甲酸薄荷酯; 和苯并三唑衍生物; 其中油溶性有机紫外线吸收剂（b）与聚合物载体（a）的重量比大于50份UV吸收剂/ 100份载体; 用于保护人类和动物毛发和皮肤免受紫外线辐射的破坏性影响。浓缩的聚合物水分散体表现出意想不到的高防晒效果和正面的皮肤感觉。

6. 发明申请

WO2009003934A1 PREPARATION OF NANOSCALAR UV ABSORBERS 审中-公开
标题翻译：纳米紫外线吸收剂的制备
公开(公告)号：WO2009003934A1
公开(公告)日：2009-01-08
申请号：PCT/EP2008/058250
申请日：2008-06-27
申请人： CIBA HOLDING INC. , MÜLLER, Stefan , HERZOG, Bernd
发明人： MÜLLER, Stefan , HERZOG, Bernd
IPC分类号： C07D251/24 , A61K8/49
CPC分类号： C07D251/24 , A61K8/4966 , A61K2800/412 , A61K2800/413 , A61Q17/04 , B82Y5/00
摘要： Disclosed is a method of preparing a composition, comprising a micronised insoluble organicUV absorber, which method comprises grinding the insoluble organic UV absorber, in coarse particle form, in a grinding apparatus comprising yttrium-stabilized zirconium oxide grinding beads, in the presence of alkyl polyglucoside having the formula C n H 2n +1 O(C 6 H 10 O 5 ) x H, in which n is an integer ranging from 8 to 16 and x is the mean polymerisation level of the glucoside moiety (C 6 H 10 O 5 ) and ranges from 1.4 to 1.6, or an ester thereof and in the presence of an antifoam agent as dispersingagent auxiliary.
摘要翻译：公开了一种制备组合物的方法，该组合物包含微粉化的不溶性有机紫外线吸收剂，该方法包括在包含钇稳定的氧化锆研磨珠的研磨装置中，在烷基聚葡糖苷存在下研磨粗颗粒形式的不溶性有机UV吸收剂具有式C n H 2n + 10（C 6 H 10 O 5）x H，其中n是8至16的整数，x是葡萄糖苷部分（C 6 H 10 O 5）的平均聚合水平，范围为1.4至1.6，或其酯消泡剂作为分散助剂的存在。

7. 发明申请

WO2006114381A1 USE OF BENZOTRIAZOLE DERIVATIVES FOR PHOTOSTABILISATION 审中-公开
标题翻译：苯并噻唑衍生物用于光化学的用途
公开(公告)号：WO2006114381A1
公开(公告)日：2006-11-02
申请号：PCT/EP2006/061686
申请日：2006-04-20
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , MÜLLER, Stefan , GIESINGER, Jochen , EHLIS, Thomas , HERZOG, Bernd , KÖNIG, Peter , KREYER, Gilbert , QUASS, Katja
发明人： MÜLLER, Stefan , GIESINGER, Jochen , EHLIS, Thomas , HERZOG, Bernd , KÖNIG, Peter , KREYER, Gilbert , QUASS, Katja
IPC分类号： A61K8/49 , A61Q17/04
CPC分类号： A61Q17/04 , A61K8/496 , A61K2800/52
摘要： Use of benzotriazole derivatives of formula (1), wherein R 1 is C 1 -C 30 alkyl; C 1 C 5 alkoxy; C 1 -C 5 alkoxycarbonyl; C 5 -C 7 cycloalkyl; C 6 -C 10 aryl; aralkyl; -SO 3 M; a radical of formula (1a) R 3 is hydrogen; C 1 C 5 alkyl; C 1 C 5 alkoxy; halogen, preferably Cl; or hydroxy; R 4 and R 5 are each independently of the other hydrogen; or d-C 5 alkyl; m is 1 or 2; n is O or 1 ; if m = 1 , R 2 is hydrogen; unsubstituted or phenyl-substituted d-C 1 -C 12 alkyl; or C 6 -C 10 aryl; if m = 2, R2 is the direct bond; or -(CH 2 ) P -; and p is 1 to 3; for enhancing the photostability of cosmetic or dermatologic compositons comprising at least one further organic UV absorber.
摘要翻译：式（1）的苯并三唑衍生物的用途，其中R 1是C 1 -C 30烷基; ç_{1 C _{5 烷氧基; ç_{1 -C _{5 烷氧基羰基; ç_{5 -C _{7 环烷基; ç_{6 -C _{10 芳基; 芳; -SO _{3 米; 式（1a）R 3的基团是氢; ç_{1 C _{5 烷基; ç_{1 C _{5 烷氧基; 卤素，优选Cl; 或羟基; R 4和R 5各自独立地为氢; 或C 1 -C 5烷基; m为1或2; n为0或1; 如果m = 1，R 2是氢; 未取代或苯基取代的C 1 -C 12烷基; 或C 6 -C 10芳基; 如果m = 2，则R2是直接键; 或 - （CH 2）2 - 。 p为1〜3; 用于增强包含至少一种其它有机UV吸收剂的化妆品或皮肤病学组合物的光稳定性。}}}}}}}}}}}}}

8. 发明申请

WO2003075875A1 UV ABSORBER COMPOSITIONS COMPRISING A HYDROXYPHENYLTRIAZINE COMPOUND 审中-公开
标题翻译：含有羟基苯乙烯化合物的紫外线吸收剂组合物
公开(公告)号：WO2003075875A1
公开(公告)日：2003-09-18
申请号：PCT/EP2003/002200
申请日：2003-03-04
申请人： CIBA SPECIALTY CHEMICALS HOLDING INC. , HAASE, Jürg , EHLIS, Thomas , BORSOS, Elek , HÜGLIN, Dietmar , HERZOG, Bernd
发明人： HAASE, Jürg , EHLIS, Thomas , BORSOS, Elek , HÜGLIN, Dietmar , HERZOG, Bernd
IPC分类号： A61K7/42
CPC分类号： A61K8/4966 , A61Q17/04
摘要： UV absorber compositions are described, comprising (a) from 1 to 99 % by weight of a hydroxyphenyltriazine compound of formula (I) wherein R 1 , R 2 and R 3 are each independently of the others C 1 -C 18 alkyl; C 2 -C 10 ,alkenyl; or phenyl-C,-C 4 alkyl; R 4 is hydrogen; or C 1 -C 5 alkyl; and (b) from 99 to 1 % by weight of a further UV absorber selected from the group of (b) hydroxyphenyltriazines that are different from component (a), (b 2 ) benzotriazoles, (b 3 ) dibenzoylmethane derivatives and (b 4 ) camphor derivatives. The compositions are suitable as UV filters in cosmetic compositions.
摘要翻译：描述了紫外线吸收剂组合物，其包含（a）1至99重量％的式（I）的羟基苯基三嗪化合物，其中R 1，R 2和R 3各自独立地为C 1 -C 18烷基; C2-C10烯基; 或苯基-C 1 -C 4烷基; R4是氢; 或C 1 -C 5烷基; 和（b）99重量％至1重量％的另外的紫外线吸收剂，其选自（b）不同于组分（a），（b 2）苯并三唑，（b3）二苯甲酰甲烷衍生物和（b4）樟脑）的羟苯基三嗪衍生物。该组合物适用于化妆品组合物中的UV过滤器。

9. 发明申请

WO2012052499A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL)TRIAZINE DERIVATIVES AS UV ABSORBERS 审中-公开
标题翻译：使用硅烷和硅氧烷双（BIPHENYL）TRIAZINE衍生物作为紫外线吸收剂
公开(公告)号：WO2012052499A1
公开(公告)日：2012-04-26
申请号：PCT/EP2011/068303
申请日：2011-10-20
申请人： BASF SE , WAGNER, Barbara , HERZOG, Bernd
发明人： WAGNER, Barbara , HERZOG, Bernd
IPC分类号： A61K8/58 , A61K8/898 , A61Q17/04
CPC分类号： A61K8/585 , A61K8/898 , A61Q17/04 , C07F7/0854
摘要： Disclosed is the use of silane and siloxane bis(biphenyl)triazine derivatives of formula (1), wherein n is a number from 1 to 4; if n = 1, X is * -L-Sil; or a radical of formula (11'), L is a linker selected from a radical of formula (2); R1, R2, R3 independently from each other are C1-C 22 alkyl; C 6 -C 20 aryl; C 1 -C 22 alkoxy; or O-C 6 -C 20 aryl; R4, R5, R6 and R7 independently from each other are hydrogen; C 1 -C 22 alkyl; C 6 -C 20 aryl; C 1 - C 22 alkoxy; or O-C 6 -C 20 aryl; b is a number from 0 to 30; c is a number from 0 to 6; and d is a number from 0 to 1; p is a number from 1 to 250; q is a number from 0 to 250; and Sil, Sil 1 and Sil 2 independently from each other are a a silane-, oligosiloxane or polysiloxane moiety; if n = 2, X is a bivalent radical of formula (1a); or (1b); x is a number from 2 to 250; y is a number from 0 to 250; and z is a number from 1 to 50; if n = 3, X is a trivalent radical containing a silane-, oligosiloxane or polysiloxane moiety; If n = 4, X is a tetravalent radical of formula (1c); and A is a radical of formula (111') as UV absorbers.
摘要翻译：公开了式（1）的硅烷和硅氧烷双（联苯）三嗪衍生物的用途，其中n为1至4的数; 如果n = 1，X为* -L-Sil; 或式（11'）的基团，L是选自式（2）的基团的连接基团; R 1，R 2，R 3彼此独立地为C 1 -C 22烷基; C6-C20芳基; C1-C22alkoxy; 或O-C6-C20芳基; R4，R5，R6和R7彼此独立地是氢; C1-C22烷基; C6-C20芳基; C 1 -C 22烷氧基; 或O-C6-C20芳基; b是从0到30的数字; c是从0到6的数字; d为0〜1的数; p是从1到250的数字; q是从0到250的数字; 和Sil，Sil1和Sil2彼此独立地是硅烷，低聚硅氧烷或聚硅氧烷部分; 如果n = 2，X是式（1a）的二价基团; 或（1b）; x是从2到250的数字; y是从0到250的数字; z为1〜50的数; 如果n = 3，X是含有硅烷，低聚硅氧烷或聚硅氧烷部分的三价基团; 如果n = 4，X是式（1c）的四价基团; 并且A是作为UV吸收剂的式（111'）基团。

10. 发明申请

WO2009016064A1 USE OF NANODISPERSIONS TO PROTECT WATER-SOLUBLE INGREDIENTS IN COSMETIC END FORMULATIONS 审中-公开
标题翻译：使用纳米尺寸来保护化妆品配方中的水溶性成分
公开(公告)号：WO2009016064A1
公开(公告)日：2009-02-05
申请号：PCT/EP2008/059568
申请日：2008-07-22
申请人： CIBA HOLDING INC. , MONGIAT, Sébastien , GRUMELARD, Julie , BASCHONG, Werner , HERZOG, Bernd
发明人： MONGIAT, Sébastien , GRUMELARD, Julie , BASCHONG, Werner , HERZOG, Bernd
IPC分类号： A61K8/04 , A61K8/55 , A61K8/60 , A61K8/891 , A61Q5/00 , A61Q19/00
CPC分类号： A61K8/676 , A61K8/04 , A61K8/345 , A61K8/375 , A61K8/4993 , A61K8/553 , A61K8/68 , A61K8/86 , A61K8/894 , A61K8/898 , A61K8/90 , A61K2800/413 , A61K2800/52 , A61K2800/522 , A61Q19/00 , B82Y5/00
摘要： The invention describes the use of a nanodispersion, which comprises: a) a membrane-forming molecule, b) a coemulsifier, c) a lipophilic component, and d) a water-soluble ingredient sensitive to oxidation in cosmetic end formulations, the nanodispersion being obtainable by (α) mixing the components (a), (b) and (c) until a homogeneous liquid is obtained (so-called nanodispersion pre-phase), and (β) adding the water or aqueous phase (discontinuous phase) which contains the water-soluble ingredient and optionally the non-aqueous polar organic solvent to the liquid obtained in step (α). Component (d) is preferably ascorbic acid or vitamin C.
摘要翻译：本发明描述了纳米分散体的使用，其包括：a）成膜分子，b）共乳化剂，c）亲脂性组分，和d）在化妆品末端制剂中对氧化敏感的水溶性成分，纳米分散体可通过（a）将组分（a），（b）和（c）混合直到获得均匀的液体（所谓的纳米分散前相）和（ß）加入水或水相（不连续相）在步骤（a）中得到的液体含有水溶性成分和任选的非水极性有机溶剂。组分（d）优选为抗坏血酸或维生素C.

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