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    • 1. 发明申请
    • GRINDING AIDS FOR MICRONIZED ORGANIC UV ABSORBERS
    • 研磨艾滋病微生物有机紫外线吸收剂
    • WO2009068469A3
    • 2009-07-16
    • PCT/EP2008065916
    • 2008-11-20
    • CIBA HOLDING INCMONGIAT SEBASTIENGRUMELARD JULIEEHLIS THOMAS
    • MONGIAT SEBASTIENGRUMELARD JULIEEHLIS THOMAS
    • A61K8/35A61K8/49A61Q17/04
    • A61K8/411A61K8/0241A61K8/494A61K8/496A61K8/4966A61K2800/412A61Q17/04
    • A method of preparing a composition, comprising (a) a micronised insoluble organic UV absorber, which method comprises grinding the insoluble organic UV absorber, in coarse particle form, in a grinding apparatus, in the presence of a grinding aid selected from the groups (b1) carboxylic acids and their salts; (b2) fatty acid esters (b3) alkyl phosphates or phosphoric acid esters; (b4) ethoxylated carboxylic acids or polyethyleneglycol (PEG) esters; (b5) fatty alcohol polyethyleneglycol (PEG) ethers of fatty alcohols; (b6) polyethylene/polypropylene -glycol ethers of saturated or unsaturated C4 - C28 fatty acids; (b7) ethoxylated alkylphenols or ethoxylated alkylphenyl ethers; (b8) esters of polyol and mono-, di- or tri-glycerides; (b9) esters of fatty acids and saccharose; (b10) sorbitan mono- and di-esters of saturated and/or unsaturated C6 - C22 fatty acids and ethylene oxide groups; and (b11) surfactants which are mainly acting as detergent or cleansing agents.
    • 一种制备组合物的方法,该方法包括(a)微粉化的不溶性有机紫外线吸收剂,该方法包括在研磨装置中,在选自以下的研磨助剂存在下以粗颗粒形式研磨不溶性有机紫外线吸收剂: b1)羧酸及其盐; (b2)脂肪酸酯(b3)烷基磷酸酯或磷酸酯; (b4)乙氧基化羧酸或聚乙二醇(PEG)酯; (b5)脂肪醇的脂肪醇聚乙二醇(PEG)醚; (b6)饱和或不饱和C 4 -C 28脂肪酸的聚乙烯/聚丙二醇醚; (b7)乙氧基化烷基酚或乙氧基化烷基苯基醚; (b8)多元醇与甘油单酯,甘油二酯或甘油三酯的酯; (b9)脂肪酸和蔗糖的酯; (b10)饱和和/或不饱和C6-C22脂肪酸和环氧乙烷基团的脱水山梨糖醇单酯和二酯; 和(b11)主要用作清洁剂或清洁剂的表面活性剂。