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1. 发明申请

WO2002087679A2 METHOD AND APPARATUS FOR ALTERING CONDUCTION PROPERTIES ALONG PATHWAYS IN THE HEART AND IN VESSELS IN CONDUCTIVE COMMUNICATION WITH THE HEART 审中-公开
标题翻译：用于改善心脏和心脏导管通路中途径导管性能的方法和装置
公开(公告)号：WO2002087679A2
公开(公告)日：2002-11-07
申请号：PCT/US2002/007673
申请日：2002-03-15
申请人： C.R. BARD, INC. , HE, Ding, Sheng , OTT, Peter
发明人： HE, Ding, Sheng , OTT, Peter
IPC分类号： A61M25/01
CPC分类号： A61B18/1492 , A61B2017/00053 , A61B2017/00084 , A61B2017/00243 , A61B2017/003 , A61B2018/00011 , A61B2018/00029 , A61B2018/00083 , A61B2018/00214 , A61B2018/00357 , A61B2018/00363 , A61B2018/00577 , A61B2018/00755 , A61B2018/00761 , A61B2018/00797 , A61B2018/00821 , A61B2018/00839 , A61B2018/00875 , A61B2018/1435 , A61B2034/2051 , A61B2218/002

2. 发明申请

WO2002087456A1 METHOD AND APPARATUS FOR ALTERING CONDUCTION PROPERTIES IN THE HEART AND IN ADJACENT VESSELS 审中-公开
标题翻译：改善心脏和相邻血管中导管性质的方法和装置
公开(公告)号：WO2002087456A1
公开(公告)日：2002-11-07
申请号：PCT/US2002/007671
申请日：2002-03-15
申请人： C.R. BARD, INC. , HE, Ding, Sheng , MacADAM, David
发明人： HE, Ding, Sheng , MacADAM, David
IPC分类号： A61B18/14
CPC分类号： A61B18/1492 , A61B2017/00053 , A61B2017/00084 , A61B2017/00243 , A61B2017/003 , A61B2018/00011 , A61B2018/00029 , A61B2018/00083 , A61B2018/00214 , A61B2018/00357 , A61B2018/00363 , A61B2018/00577 , A61B2018/00755 , A61B2018/00761 , A61B2018/00797 , A61B2018/00821 , A61B2018/00839 , A61B2018/00875 , A61B2018/1435 , A61B2034/2051 , A61B2218/002
摘要： Method and apparatus for treating conductive irregularities in the heart, particularly atrial fibrillation and accessory path arrythmias. An ablative catheter is positioned relative to an inter-atrial electrical pathway, or a vicinity of accessory paths such as the coronary sinus or fossa ovalis, and actuated to form a lesion that partially or completely blocks electrical conduction in at least one direction along the pathway.
摘要翻译：用于治疗心脏中的导电不规则物的方法和装置，特别是心房颤动和辅助路径性心律失常。烧蚀导管相对于心房间电路或邻近的附近路径（例如冠状窦或卵圆窝）定位并且被致动以形成部分地或完全阻挡沿着该路径的至少一个方向的电传导的病变。

3. 发明申请

WO2005115232A1 HIGH DENSITY ATRIAL FIBRILLATION CYCLE LENGTH (AFCL) DETECTION AND MAPPING SYSTEM 审中-公开
标题翻译：高密度ATRIAL FIBRILLATION循环长度（AFCL）检测和绘图系统
公开(公告)号：WO2005115232A1
公开(公告)日：2005-12-08
申请号：PCT/US2005/015406
申请日：2005-05-03
申请人： C.R. BARD, INC. , MASHIMO, Minoru , FANIER, Sylvain , MACADAM, David, P. , HAIISAGUERRE, Michael , DUBOIS, Remi , COLLINS, Tim , HE, Ding, Sheng
发明人： MASHIMO, Minoru , FANIER, Sylvain , MACADAM, David, P. , HAIISAGUERRE, Michael , DUBOIS, Remi , COLLINS, Tim , HE, Ding, Sheng
IPC分类号： A61B5/0402
CPC分类号： A61B5/04014 , A61B5/0422 , A61B5/046 , A61B5/7257 , A61B18/14 , A61B18/1492 , A61B2018/00351 , A61B2018/00577 , A61B2018/00642 , A61B2018/00839
摘要： Systems and methods to assist in locating the focus of an atrial fibrillation include the association of atrial fibrillation cycle length values and statistics relating thereto with temporal locations on an electrogram of a given electrode, and/or the coordination of electrode locations with respective the spectral analyses of electrogram signals and further parameters and statistics relating thereto. Ablation therapy can proceed under guidance of such information.
摘要翻译：协助定位心房纤颤的焦点的系统和方法包括将心房颤动循环长度值与其相关的统计学与给定电极的电描图上的时间位置的关联，和/或电极位置与各自的光谱分析的协调的电描记信号及其相关参数和统计资料。消融治疗可以在这种信息的指导下进行。

4. 发明申请

WO2005115231A1 ELECTROPHYSIOLOGY SYSTEM FOR MAPPING AND ABLATING ARRHYTHMIAS 审中-公开
标题翻译：用于绘制和解剖ARRHYTHMIAS的电生理系统
公开(公告)号：WO2005115231A1
公开(公告)日：2005-12-08
申请号：PCT/US2005/017080
申请日：2005-05-17
申请人： C.R. BARD, INC. , MacADAM, David , HE, Ding, Sheng
发明人： MacADAM, David , HE, Ding, Sheng
IPC分类号： A61B5/04
CPC分类号： A61B18/1492 , A61B5/042 , A61B2018/00214 , A61B2018/00839
摘要： An electrophysiology system for mapping and/or ablating tissue includes a catheter having a plurality of electrically active sites. The system includes a controller providing a user interface through which the plurality of sites may be controlled. The sites may be accessed individually or in groups. In addition, the order and timing of the accessing of specific electrically active sites may be controlled in a manual or automated fashion.
摘要翻译：用于测绘和/或消融组织的电生理系统包括具有多个电活性部位的导管。该系统包括提供用户界面的控制器，通过该用户界面可以控制多个站点。这些网站可以单独或分组访问。此外，可以以手动或自动的方式控制特定电活动场所的访问顺序和时间。

5. 发明申请

WO2012058461A1 BIOIMPEDANCE-ASSISTED PLACEMENT OF A MEDICAL DEVICE 审中-公开
标题翻译：医疗设备的生物安全辅助放置
公开(公告)号：WO2012058461A1
公开(公告)日：2012-05-03
申请号：PCT/US2011/058138
申请日：2011-10-27
申请人： C.R.BARD, INC. , HE, Ding, Sheng , CIAVARELLA, David, J. , BURNSIDE, Eddie, K.
发明人： HE, Ding, Sheng , CIAVARELLA, David, J. , BURNSIDE, Eddie, K.
IPC分类号： A61B18/00
CPC分类号： A61M25/0105 , A61B5/068 , A61B17/00234 , A61B34/20 , A61B2017/00026 , A61B2017/00331 , A61B2034/2051 , A61M25/01 , A61M2025/0166
摘要： A system and method for guiding a catheter or other medical device to a desired target destination within the vasculature of a patient via bioimpedance measurements is disclosed. The target destination in one embodiment includes placement of the catheter such that a distal tip thereof is disposed proximate the heart, e.g., the junction of the right atrium and superior vena cava. In one embodiment the method for guiding the catheter comprises introducing the catheter into a vessel of the patient, the catheter defining a lumen through which fluids can be infused into the vasculature of the patient. The catheter is advanced toward a target destination within the vasculature. A first impedance value based on intravascular detection of at least one electrical property related to a first tissue surface of the vessel is calculated to enable determination of the proximity of a distal end of the catheter to the target destination.
摘要翻译：公开了一种用于通过生物阻抗测量将导管或其他医疗装置引导到患者脉管系统内的期望目的地目的地的系统和方法。在一个实施例中的目标目的地包括导管的放置，使得其远侧末端设置在心脏附近，例如右心房和上腔静脉的连接处。在一个实施例中，用于引导导管的方法包括将导管引入患者的容器中，该导管限定了内腔，流体可以通过内腔输注到患者的脉管系统中。导管朝向脉管系统内的目标目标前进。计算基于与血管的第一组织表面相关的至少一个电性质的血管内检测的第一阻抗值，以使得能够确定导管的远端与目的地的接近度。

6. 发明申请

WO2005011475A2 OPTIMIZATION METHOD FOR CARDIAC RESYNCHRONIZATION THERAPY 审中-公开
标题翻译：心脏再同步治疗的优化方法
公开(公告)号：WO2005011475A2
公开(公告)日：2005-02-10
申请号：PCT/US2004/024469
申请日：2004-07-28
申请人： MARCUS, Frank, I. , HE, Ding, Sheng
发明人： MARCUS, Frank, I. , HE, Ding, Sheng
IPC分类号： A61B
CPC分类号： A61B5/1107 , A61B5/6869 , A61B5/7217 , A61N1/3627 , A61N1/36542 , A61N1/3682 , A61N1/3684
摘要： The patterns of contraction and relaxation of the heart before and during left ventricular or biventricular pacing are analyzed and displayed in real time mode to assist physicians to screen patients for cardiac resynchronization therapy, to set the optimal AN or right ventricle to left ventricle interval delay, and to select the site(s) of pacing that result in optimal cardiac performance. The system includes an accelerometer sensor (40); a programmable pace maker (35, 41), a computer data analysis module (32), and may also include a 2D and 3D visual graphic display of analytic results (43, 44), i.e. a Ventricular Contraction Map. A feedback network (32) provides direction for optimal pacing leads placement. The method includes selecting a location to place the leads of a cardiac pacing device, collecting seismocardiographic (SCG) data corresponding to heart motion during paced beats of a patient's heart, determining hemodynamic and electrophysiological parameters based on the SCG data, repeating the preceding steps for another lead placement location, and selecting a lead placement location that provides the best cardiac performance by comparing the calculated hemodynamic and electrophysiological parameters for each different lead placement location.
摘要翻译：在实时模式下分析和显示左心室或双心室起搏之前和期间的心脏收缩和舒张模式，以帮助医生筛选患者进行心脏再同步治疗，设置最佳的AN或右心室至左心室间隔延迟，并选择导致心脏性能最佳的起搏部位。该系统包括加速计传感器（40）; 可编程起搏器（35,41），计算机数据分析模块（32），并且还可以包括分析结果（43,44）的2D和3D视觉图形显示，即心室收缩图。反馈网络（32）为最佳起搏引线放置提供指导。该方法包括选择放置心脏起搏装置的导线的位置，在患者心脏的起搏节拍期间收集与心脏运动对应的心震波（SCG）数据，基于SCG数据确定血液动力学和电生理参数，重复前述步骤另一导联放置位置，并通过比较针对每个不同导联放置位置计算的血液动力学和电生理学参数来选择提供最佳心脏表现的导联放置位置。

7. 发明申请

WO2005115226A2 MAPPING AND ABLATION METHOD FOR THE TREATMENT OF VENTRICULAR TACHYCARDIA 审中-公开
标题翻译：用于治疗静脉曲霉的映射和排列方法
公开(公告)号：WO2005115226A2
公开(公告)日：2005-12-08
申请号：PCT/US2005/017081
申请日：2005-05-17
申请人： C.R.BARD, INC. , MacADAM, David , HE, Ding, Sheng
发明人： MacADAM, David , HE, Ding, Sheng
IPC分类号： A61B5/00
CPC分类号： A61B18/1492 , A61B5/042 , A61B2018/00214 , A61B2018/00839
摘要： An apparatus for mapping and/or ablating tissue includes a braided conductive member that that may be inverted to provide a ring-shaped surface. When a distal tip of the braided conductive member is retracted within the braided conductive member, the lack of a protrusion allows the ring-shaped surface to contact a tissue wall such as a cardiac wall. In an alternative configuration, the braided conductive member may be configured with the distal portion forming a proboscis that can be used to stably position the braided conductive member relative to a blood vessel, such as a ventricular outflow tract. The braided conductive member has a plurality of electronically active sites that may be accessed individually for stable mapping over a broad area for stable mapping or ablation to form broad and deep lesions.
摘要翻译：一种用于测绘和/或消融组织的装置包括可被倒置以提供环形表面的编织导电构件。当编织导电构件的远侧末端缩回到编织导电构件内时，缺少凸起允许环形表面接触诸如心脏壁的组织壁。在替代配置中，编织导电构件可以被构造成具有形成长鼻的远端部分，其可用于相对于诸如心室流出道的血管来稳定地定位编织导电构件。编织导电构件具有多个电子活性位点，其可以单独访问以用于在广泛区域上的稳定映射以用于稳定的映射或消融以形成宽而深的损伤。

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