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1. 发明申请

WO2005011475A2 OPTIMIZATION METHOD FOR CARDIAC RESYNCHRONIZATION THERAPY 审中-公开
标题翻译：心脏再同步治疗的优化方法
公开(公告)号：WO2005011475A2
公开(公告)日：2005-02-10
申请号：PCT/US2004/024469
申请日：2004-07-28
申请人： MARCUS, Frank, I. , HE, Ding, Sheng
发明人： MARCUS, Frank, I. , HE, Ding, Sheng
IPC分类号： A61B
CPC分类号： A61B5/1107 , A61B5/6869 , A61B5/7217 , A61N1/3627 , A61N1/36542 , A61N1/3682 , A61N1/3684
摘要： The patterns of contraction and relaxation of the heart before and during left ventricular or biventricular pacing are analyzed and displayed in real time mode to assist physicians to screen patients for cardiac resynchronization therapy, to set the optimal AN or right ventricle to left ventricle interval delay, and to select the site(s) of pacing that result in optimal cardiac performance. The system includes an accelerometer sensor (40); a programmable pace maker (35, 41), a computer data analysis module (32), and may also include a 2D and 3D visual graphic display of analytic results (43, 44), i.e. a Ventricular Contraction Map. A feedback network (32) provides direction for optimal pacing leads placement. The method includes selecting a location to place the leads of a cardiac pacing device, collecting seismocardiographic (SCG) data corresponding to heart motion during paced beats of a patient's heart, determining hemodynamic and electrophysiological parameters based on the SCG data, repeating the preceding steps for another lead placement location, and selecting a lead placement location that provides the best cardiac performance by comparing the calculated hemodynamic and electrophysiological parameters for each different lead placement location.
摘要翻译：在实时模式下分析和显示左心室或双心室起搏之前和期间的心脏收缩和舒张模式，以帮助医生筛选患者进行心脏再同步治疗，设置最佳的AN或右心室至左心室间隔延迟，并选择导致心脏性能最佳的起搏部位。该系统包括加速计传感器（40）; 可编程起搏器（35,41），计算机数据分析模块（32），并且还可以包括分析结果（43,44）的2D和3D视觉图形显示，即心室收缩图。反馈网络（32）为最佳起搏引线放置提供指导。该方法包括选择放置心脏起搏装置的导线的位置，在患者心脏的起搏节拍期间收集与心脏运动对应的心震波（SCG）数据，基于SCG数据确定血液动力学和电生理参数，重复前述步骤另一导联放置位置，并通过比较针对每个不同导联放置位置计算的血液动力学和电生理学参数来选择提供最佳心脏表现的导联放置位置。

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