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1. 发明申请

WO2003062824A1 LATERAL FLOW QUANTITATIVE ASSAY METHOD AND STRIP AND LASER-INDUCED FLUOERESCENCE DETECTION DEVICE THEREFOR 审中-公开
标题翻译：侧流量子测定方法和条纹及其激光诱导的荧光检测装置
公开(公告)号：WO2003062824A1
公开(公告)日：2003-07-31
申请号：PCT/KR2003/000151
申请日：2003-01-23
申请人： BODITECH INC. , NAHM, Kie-Bong , CHOI, Eui-Yeol , JEONG, Dong-Seok , JUNG, Jin-Ha , MOON, Joung-Dae , KIM, Young-Min , LEE, Keun-Woo , AHN, Jae-Soon , JEONG, Young-Eui , PARK, Sang-Yeol , KIM, Hyun-Mi , LEE, Byung-Ryong
发明人： NAHM, Kie-Bong , CHOI, Eui-Yeol , JEONG, Dong-Seok , JUNG, Jin-Ha , MOON, Joung-Dae , KIM, Young-Min , LEE, Keun-Woo , AHN, Jae-Soon , JEONG, Young-Eui , PARK, Sang-Yeol , KIM, Hyun-Mi , LEE, Byung-Ryong
IPC分类号： G01N33/543
CPC分类号： G01N21/6428 , B01L3/5023 , B01L2300/0825 , B01L2300/087 , G01N21/6402 , G01N21/645 , G01N30/74 , G01N30/90 , G01N33/558 , G01N33/582 , G02B5/08
摘要： Method and apparatus for lateral flow quantitative assay for bio-analytes are disclosed. The invention includes a highly sensitive bioassay strip for multiple analytes and its subsequent quantitation by an improved laser-induced epi-fluorescence detection apparatus featuring 10 -12 g/ml as the lowest analyte concentration for detection. In addition, the lateral flow assay strip of the subject invention enables simultaneous quantitation of multiple analytes.
摘要翻译：公开了用于生物分析物的横向流量定量测定的方法和装置。本发明包括用于多种分析物的高度灵敏的生物测定条，其随后通过改进的激光诱导的外荧光检测装置进行定量，其具有10-12μg/ ml作为用于检测的最低分析物浓度。此外，本发明的侧流测定条能够同时定量多种分析物。

2. 发明申请

WO2005066624A1 A METHOD FOR THE DETECTION OF LATERAL FLOW ASSAY AND STRIP AND LASER-INDUCED EPIFLUORESCENCE AND COMPACT SCANNER THEREFOR 审中-公开
标题翻译：检测侧流测定方法及其条纹和激光诱导型EP ENCE AND OR OR OR OR OR OR OR OR OR
公开(公告)号：WO2005066624A1
公开(公告)日：2005-07-21
申请号：PCT/KR2005/000016
申请日：2005-01-05
申请人： BIO-MED PHOTONICS CO., LTD. , BODITECHMED INC. , NAHM, Kie-Bong , CHOI, Eui-Yeol , KIM, Jae-Hoon
发明人： NAHM, Kie-Bong , CHOI, Eui-Yeol , KIM, Jae-Hoon
IPC分类号： G01N30/88
CPC分类号： G01N33/558 , G01N21/6428 , G01N21/645 , G01N21/8483
摘要： Disclosed is a lateral flow quantitative assay method capable of quantitatively determining the concentration and analyzing the spatial distribution of a disease marker by employing the principle of the laser-induced fluorescence detection technique, which is based on detecting emitted fluorescence when laser light is focused to the disease marker deposited onto a lateral flow quantitative assay chip. The present invention discloses a strip, a laser-induced epifluorescence detection device and a small scanner for the assay method. The present assay method is advantageous in terms of allowing quantitative point-of-care diagnostics in hospitals, being capable of specifically detecting a disease marker by optimizing a lateral flow assay biochip for diagnosis of a specific disease, allowing more accurate quantitative analysis of analytes, and being capable of simultaneously analyzing several cancer markers, reducing the hook effect and expanding the detection range and accurately measuring concentration of analytes.
摘要翻译：公开了一种侧流定量测定方法，其能够通过采用激光诱导荧光检测技术的原理定量测定浓度并分析疾病标记物的空间分布，该方法基于当激光聚焦于疾病标记物沉积在侧流定量测定芯片上。本发明公开了一种用于测定方法的条带，激光诱导的落射荧光检测装置和小型扫描仪。本测定方法在医院中允许定量点护理诊断方面是有利的，能够通过优化用于诊断特定疾病的侧流测定生物芯片来特异性检测疾病标记物，从而允许对分析物进行更准确的定量分析，并能够同时分析几种癌症标志物，减少钩效应，扩大检测范围，准确测量分析物的浓度。

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