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1. 发明申请

WO2011008030A3 CHROMATOGRAPHIC SYSTEM FOR NUCLEIC ACID DETECTION 审中-公开
标题翻译：用于核酸检测的色谱系统
公开(公告)号：WO2011008030A3
公开(公告)日：2011-05-19
申请号：PCT/KR2010004598
申请日：2010-07-15
申请人： BODITECH MED INC , CHOI EUI-YUL , NAHM KIE-BONG , JEONG DONG-SEOK , KIM SUNG-JOONG
发明人： CHOI EUI-YUL , NAHM KIE-BONG , JEONG DONG-SEOK , KIM SUNG-JOONG
IPC分类号： C12Q1/68 , G01N30/90 , G01N33/50
CPC分类号： C12Q1/708 , C12Q1/70 , G01N33/5308 , G01N33/54386 , C12Q2565/625 , C12Q2563/107
摘要： The present invention relates to a strip for detecting nucleic acids in analysis samples, based on the principles of lateral motion development technique and sequence-specific hybridization of nucleic acids, and to a nucleic acid detection system comprising the strip and also to a specific nucleic acid detection method employing the strip. The strip, system and method of the present invention allow not only a very high degree of ease in use but also of detection sensitivity and specificity, and allow accurate and rapid analysis even when a small amount of nucleic acid is employed.
摘要翻译：本发明涉及一种基于横向运动发育技术和核酸的序列特异性杂交的原理以及包含该条带以及特定核酸的核酸检测系统的分析样品中检测核酸的条带检测方法。本发明的条，系统和方法不仅使用非常高的易用性，而且允许检测灵敏度和特异性，并且即使在使用少量的核酸时也允许准确和快速的分析。

2. 发明申请

WO2009099269A1 SYSTEM FOR THE QUANTITATIVE MEASUREMENT OF GLYCOHEMOGLOBIN AND A METHOD FOR MEASURING THE CONTENT OF GLYCOHEMOGLOBIN USING THE SAME 审中-公开
标题翻译：糖蛋白定量测定系统及使用该蛋白质测定糖蛋白含量的方法
公开(公告)号：WO2009099269A1
公开(公告)日：2009-08-13
申请号：PCT/KR2008/006306
申请日：2008-10-24
申请人： BODITECHMED INC. , CHOI, Eui Yul , NAHM, Kie Bong , KIM, Jae Hoon , JEONG, Dong Seok , PARK, Sang Yeol , MOON, Joung Dae , JUNG, Jin Ha , KIM, Young Min , JUNG, So Young , PARK, Ae Kyung , KIM, Byeong Chul , KIM, Sung Joong
发明人： CHOI, Eui Yul , NAHM, Kie Bong , KIM, Jae Hoon , JEONG, Dong Seok , PARK, Sang Yeol , MOON, Joung Dae , JUNG, Jin Ha , KIM, Young Min , JUNG, So Young , PARK, Ae Kyung , KIM, Byeong Chul , KIM, Sung Joong
IPC分类号： G01N33/72 , G01N30/88 , B01D15/08
CPC分类号： G01N33/723 , G01N33/726
摘要： The present invention provides a device for simultaneously detecting hemoglobin and glycohemoglobin in blood, comprising a lateral flow assay strip, a laser-induced epifluorescence detection device, and an LED detection device, and a simple method for simultaneously quantifying hemoglobin and glycohemoglobin in blood by an immunological method using the same.
摘要翻译：本发明提供一种用于同时检测血液中的血红蛋白和糖血红蛋白的装置，包括侧流测定条，激光诱导的落射荧光检测装置和LED检测装置，以及用于通过以下步骤同时定量血液中的血红蛋白和糖血红蛋白的简单方法：免疫学方法使用相同。

3. 发明申请

WO2009064079A1 PERCUTANEOUS BIOLOGICAL FLUID SAMPLING AND PRE SHAKING DEVICES AND METHODS 审中-公开
标题翻译： PERCUTANEOUS生物流体采样和预擦洗装置和方法
公开(公告)号：WO2009064079A1
公开(公告)日：2009-05-22
申请号：PCT/KR2008/006223
申请日：2008-10-21
申请人： BODITECHMED INC. , CHOI, Eui Yul , NAHM, Kie Bong , KIM, Jae Hoon , JEONG, Dong Seok , PARK, Sang Yeol , MOON, Joung Dae , JUNG, Jin Ha , KIM, Young Min , JUNG, So Young , PARK, Ae Kyung , KIM, Byeong Chul
发明人： CHOI, Eui Yul , NAHM, Kie Bong , KIM, Jae Hoon , JEONG, Dong Seok , PARK, Sang Yeol , MOON, Joung Dae , JUNG, Jin Ha , KIM, Young Min , JUNG, So Young , PARK, Ae Kyung , KIM, Byeong Chul
IPC分类号： G01N33/487
CPC分类号： A61B5/15142 , A61B5/150022 , A61B5/150175 , A61B5/150343 , A61B5/150351 , A61B5/150404 , A61B5/150503 , A61B5/150755 , A61B5/15105
摘要： Provided is a device for sampling and pretreating biological fluid. It comprises: a piercing unit having at a lower portion a capillary tip which is to be inserted into skin to a predetermined depth to take biological fluid therethrough; a dropper, connected to an upper portion of the piercing unit, having an injection tube at an upper portion thereof, the injection tube communicating with the capillary tip; and a reagent container, designed to accommodate the piercing unit therein in an airtight manner so as to seal an outer circumference of the piercing unit, functioning to contain a reagent for treating the biological fluid of the capillary tip of the piercing unit. The device allows even a novice to sample and pre treat biological fluid with high accuracy without the use of expensive precision devices. The device employs fewer expendable supplies, thus providing higher convenience for the user.
摘要翻译：提供了用于取样和预处理生物流体的装置。它包括：刺穿单元，其具有在下部的毛细管尖端，所述毛细管尖端将被插入到皮肤中至预定深度以使生物流体通过其中; 连接到穿刺单元的上部的滴管，在其上部具有注射管，所述注射管与毛细管尖端连通; 以及试剂容器，其设计成以气密方式容纳穿孔单元，以密封穿刺单元的外周，用于容纳用于处理穿孔单元的毛细管尖端的生物流体的试剂。该装置甚至允许新手在不使用昂贵的精密装置的情况下以高精度对生物流体进行采样和预处理。该设备使用更少的消耗品，从而为用户提供更高的便利。

4. 发明申请

WO2005066624A1 A METHOD FOR THE DETECTION OF LATERAL FLOW ASSAY AND STRIP AND LASER-INDUCED EPIFLUORESCENCE AND COMPACT SCANNER THEREFOR 审中-公开
标题翻译：检测侧流测定方法及其条纹和激光诱导型EP ENCE AND OR OR OR OR OR OR OR OR OR
公开(公告)号：WO2005066624A1
公开(公告)日：2005-07-21
申请号：PCT/KR2005/000016
申请日：2005-01-05
申请人： BIO-MED PHOTONICS CO., LTD. , BODITECHMED INC. , NAHM, Kie-Bong , CHOI, Eui-Yeol , KIM, Jae-Hoon
发明人： NAHM, Kie-Bong , CHOI, Eui-Yeol , KIM, Jae-Hoon
IPC分类号： G01N30/88
CPC分类号： G01N33/558 , G01N21/6428 , G01N21/645 , G01N21/8483
摘要： Disclosed is a lateral flow quantitative assay method capable of quantitatively determining the concentration and analyzing the spatial distribution of a disease marker by employing the principle of the laser-induced fluorescence detection technique, which is based on detecting emitted fluorescence when laser light is focused to the disease marker deposited onto a lateral flow quantitative assay chip. The present invention discloses a strip, a laser-induced epifluorescence detection device and a small scanner for the assay method. The present assay method is advantageous in terms of allowing quantitative point-of-care diagnostics in hospitals, being capable of specifically detecting a disease marker by optimizing a lateral flow assay biochip for diagnosis of a specific disease, allowing more accurate quantitative analysis of analytes, and being capable of simultaneously analyzing several cancer markers, reducing the hook effect and expanding the detection range and accurately measuring concentration of analytes.
摘要翻译：公开了一种侧流定量测定方法，其能够通过采用激光诱导荧光检测技术的原理定量测定浓度并分析疾病标记物的空间分布，该方法基于当激光聚焦于疾病标记物沉积在侧流定量测定芯片上。本发明公开了一种用于测定方法的条带，激光诱导的落射荧光检测装置和小型扫描仪。本测定方法在医院中允许定量点护理诊断方面是有利的，能够通过优化用于诊断特定疾病的侧流测定生物芯片来特异性检测疾病标记物，从而允许对分析物进行更准确的定量分析，并能够同时分析几种癌症标志物，减少钩效应，扩大检测范围，准确测量分析物的浓度。

5. 发明申请

WO2003085387A1 AN APPARATUS FOR THE DETECTION OF LASER-INDUCED EPIFLUORESCENCE 审中-公开
标题翻译：用于检测激光诱导的抗生素的装置
公开(公告)号：WO2003085387A1
公开(公告)日：2003-10-16
申请号：PCT/KR2003/000666
申请日：2003-04-03
申请人： BIOMED PHOTONICS CO., LTD. , NAHM, Kie-Bong
发明人： NAHM, Kie-Bong
IPC分类号： G01N21/64
CPC分类号： G01N21/6452 , G01N2201/0637
摘要： The present invention involves an apparatus for detection of laser-induced fluorescence, wherein a sample substrate is made of transparent or semi-translucent materials and the apparatus is equipped with a reflector that reflects the reflected light from the sample and the scattered light of the excitation light; a focusing system that collects light transmitted through the sample; a spatial filter that eliminates noise component from the reflected light from the reflector and/or output from the focusing system; a collimator that converts the light passed through the focusing system to a parallel light; a fluorescence filter that filters only the fluorescence from light transmitted through the collimator; and a photodetector that converts the output light from the fluorescence filter into the electric signal. The present apparatus may further be equipped with an optical feedback system that is placed in the rear of the sample and sends light transmitted through the sample back to the sample. Therefore, the apparatus according to the present invention provides higher light focusing efficiency and improved utility of the excitation light energy by recycling the transmitted light to increase the fluorescence yield, as compared with the conventional system.
摘要翻译：本发明涉及一种用于检测激光诱导荧光的装置，其中样品基底由透明或半透明材料制成，并且该装置配备有反射来自样品的反射光和激发的散射光的反射器光; 收集透过样品的光的聚焦系统; 空间滤波器，其消除来自反射器的反射光的噪声分量和/或从聚焦系统的输出; 将通过聚焦系统的光转换成平行光的准直器; 荧光滤光片，仅透过准直仪的光线过滤荧光; 以及将来自荧光滤波器的输出光转换成电信号的光电检测器。本装置还可以配备有光学反馈系统，其被放置在样品的后部并将透过样品的光发送回样品。因此，与常规系统相比，根据本发明的装置提供了更高的聚光效率，并且通过再循环透射光以提高荧光产量来提高激发光能的效用。

6. 发明申请

WO2003062824A1 LATERAL FLOW QUANTITATIVE ASSAY METHOD AND STRIP AND LASER-INDUCED FLUOERESCENCE DETECTION DEVICE THEREFOR 审中-公开
标题翻译：侧流量子测定方法和条纹及其激光诱导的荧光检测装置
公开(公告)号：WO2003062824A1
公开(公告)日：2003-07-31
申请号：PCT/KR2003/000151
申请日：2003-01-23
申请人： BODITECH INC. , NAHM, Kie-Bong , CHOI, Eui-Yeol , JEONG, Dong-Seok , JUNG, Jin-Ha , MOON, Joung-Dae , KIM, Young-Min , LEE, Keun-Woo , AHN, Jae-Soon , JEONG, Young-Eui , PARK, Sang-Yeol , KIM, Hyun-Mi , LEE, Byung-Ryong
发明人： NAHM, Kie-Bong , CHOI, Eui-Yeol , JEONG, Dong-Seok , JUNG, Jin-Ha , MOON, Joung-Dae , KIM, Young-Min , LEE, Keun-Woo , AHN, Jae-Soon , JEONG, Young-Eui , PARK, Sang-Yeol , KIM, Hyun-Mi , LEE, Byung-Ryong
IPC分类号： G01N33/543
CPC分类号： G01N21/6428 , B01L3/5023 , B01L2300/0825 , B01L2300/087 , G01N21/6402 , G01N21/645 , G01N30/74 , G01N30/90 , G01N33/558 , G01N33/582 , G02B5/08
摘要： Method and apparatus for lateral flow quantitative assay for bio-analytes are disclosed. The invention includes a highly sensitive bioassay strip for multiple analytes and its subsequent quantitation by an improved laser-induced epi-fluorescence detection apparatus featuring 10 -12 g/ml as the lowest analyte concentration for detection. In addition, the lateral flow assay strip of the subject invention enables simultaneous quantitation of multiple analytes.
摘要翻译：公开了用于生物分析物的横向流量定量测定的方法和装置。本发明包括用于多种分析物的高度灵敏的生物测定条，其随后通过改进的激光诱导的外荧光检测装置进行定量，其具有10-12μg/ ml作为用于检测的最低分析物浓度。此外，本发明的侧流测定条能够同时定量多种分析物。

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