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1. 发明申请

WO2010021702A9 SELF-AVOIDING MOLECULAR RECOGNITION SYSTEMS IN DNA AMPLIFICATION 审中-公开
公开(公告)号：WO2010021702A9
公开(公告)日：2010-02-25
申请号：PCT/US2009/004718
申请日：2009-08-19
申请人： BENNER, Steven, Albert , HOSHIKA, Shuichi , CHEN, Fei
发明人： BENNER, Steven, Albert , HOSHIKA, Shuichi , CHEN, Fei
IPC分类号： C07H21/04 , A61K31/70 , C12P19/34
摘要： This invention concerns self-avoiding molecular recognition systems (SAMRS), DNA-like molecules that that bind to natural DNA having a Watson-Crick complementary sequence, but do not bind to other SAMRS-containing oligonucleotide analogs when SAMRS components are paired with other SAMRS components and, where once bound, serve as primers for polymerase extension, as well as templates in reverse priming characteristic of the polymerase chain reaction. As a product of extensive experimentation, SAMRS building blocks are disclosed that confer these properties on oligonucleotides that contain them, positions in primers where SAMRS building blocks are preferably placed, and a critical mass of biophysical data to support heuristic rules to permit design of SAMRS component-containing sequences that can be used as primers in primer extension and PCR reactions. Also disclosed are compositions containing a plurality of these oligonucleotides that can be used in kits, and processes using these compositions to PCR amplify target oligonucleotides.

2. 发明申请

WO2009154733A2 POLYMERASE INCORPORATION OF NON-STANDARD NUCLEOTIDES 审中-公开
标题翻译：聚合物纳入非标准核素
公开(公告)号：WO2009154733A2
公开(公告)日：2009-12-23
申请号：PCT/US2009/003595
申请日：2009-06-16
申请人： BENNER, Steven, Albert , CHEN, Fei , YANG, Zunyi
发明人： BENNER, Steven, Albert , CHEN, Fei , YANG, Zunyi
IPC分类号： C12Q1/68 , C12P19/40
CPC分类号： C12Q1/6853 , C12P19/34 , C12Q1/686 , C12Q2521/101 , C12Q2525/117 , C12Q2525/191
摘要： The disclosed invention teaches processes to amplify oligonucleotides by contacting templates and primers with DNA polymerases and triphosphates of non-standard nucleotides, which form nucleobase pairs fitting the standard Watson-Crick geometry, but joined by hydrogen bonding patterns different from those that join standard A:T and G:C pairs. Thus, this invention relates to nucleotide analogs and their derivatives that, when incorporated into DNA and RNA, expand the number of replicatable nucleotides beyond the four found in standard DNA and RNA. The invention further relates to polymerases that incorporate those non-standard nucleotide analogs into oligonucleotide products using the corresponding triphosphate derivatives, and more specifically, polymerases and non-standard nucleoside triphosphates that support the polymerase chain reaction (PCR), including PCR where the products contain more than one non-standard nucleotide unit. Examples are provides that show this process using 6-amino-5-nitro-3-(l'-beta- D-2'-deoxyribofuranosyl)-2(lH)-pyridone to implement the non-standard "small" donor-donor- acceptor (pyDDA) hydrogen bonding pattern, and 2-amino-8-(r-beta-D-2'-deoxyribofuranosyl)- imidazo[l,2-α]-l,3,5-triazin-4(8H)-one to implement the "large" acceptor-acceptor-donor (puAAD) pattern.
摘要翻译：所公开的发明教导了通过使模板和引物与DNA聚合酶和非标准核苷酸的三磷酸接触来扩增寡核苷酸的过程，其形成适合标准Watson-Crick几何形状的核碱基对，但是通过与加入标准A： T和G：C对。因此，本发明涉及核苷酸类似物及其衍生物，其在掺入DNA和RNA时扩大超过标准DNA和RNA中发现的四种可重复核苷酸的数量。本发明还涉及使用相应的三磷酸衍生物，更具体地，支持聚合酶链式反应（PCR）的聚合酶和非标准核苷三磷酸（包括产物含有的PCR）的寡核苷酸产物，将这些非标准核苷酸类似物结合到聚合酶中的聚合酶多个非标准核苷酸单位。提供了使用6-氨基-5-硝基-3-（1'-β-2-脱氧三呋喃糖基）-2（1H） - 吡啶酮来实施非标准“小”供体 - 供体的实施例 - 受体（pyDDA）氢键图案和2-氨基-8-（r-β-D-2'-脱氧三呋喃糖基） - 咪唑并[1,2-a] -1,3,5-三嗪-4（8H） - 执行“大”受体 - 受体 - 供体（puAAD）模式。

3. 发明申请

WO2014021900A1 HEAVY HYDROCARBON REMOVAL FROM A NATURAL GAS STREAM 审中-公开
公开(公告)号：WO2014021900A1
公开(公告)日：2014-02-06
申请号：PCT/US2012/049506
申请日：2012-08-03
申请人： AIR PRODUCTS AND CHEMICALS, INC. , CHEN, Fei , LUO, Xukun , OTT, Christopher, Michael , ROBERTS, Mark, Julian , KRISHNAMURTHY, Gowri
发明人： CHEN, Fei , LUO, Xukun , OTT, Christopher, Michael , ROBERTS, Mark, Julian , KRISHNAMURTHY, Gowri
IPC分类号： C10L3/10 , F25J1/00 , F25J3/02 , F25J3/06
CPC分类号： C10L3/101 , F25J1/0022 , F25J1/0045 , F25J1/0052 , F25J1/0212 , F25J1/0238 , F25J3/0209 , F25J3/0233 , F25J3/0247 , F25J3/061 , F25J3/0635 , F25J3/065 , F25J2200/02 , F25J2200/40 , F25J2200/70 , F25J2205/40 , F25J2205/60 , F25J2205/66 , F25J2210/06 , F25J2220/64 , F25J2230/30 , F25J2230/60 , F25J2245/02 , F25J2245/90
摘要： A method and apparatus of removing heavy hydrocarbons from a natural gas feed stream, the method comprising using first and second hydrocarbon removal systems in series such that the first system processes the natural gas feed stream to produce a heavy hydrocarbon depleted natural gas stream and the second system processes at least a portion of the heavy hydrocarbon depleted natural gas stream from the first system to produce a natural gas stream lean in heavy hydrocarbons, wherein one of said systems is a adsorption system that comprises one or more beds of adsorbent for adsorbing and thereby removing heavy hydrocarbons from a heavy hydrocarbon containing natural gas, and the other of said systems is a gas-liquid separation system for separating a heavy hydrocarbon containing natural gas into a heavy hydrocarbon depleted natural gas vapor and a heavy hydrocarbon enriched liquid.

4. 发明申请

WO2003048771A2 DEVICE FOR ANALYSING ANALYTE COMPOUNDS AND USE HEREOF 审中-公开
标题翻译：用于分析分析化合物的装置并在此使用
公开(公告)号：WO2003048771A2
公开(公告)日：2003-06-12
申请号：PCT/DK2002/000817
申请日：2002-12-03
申请人： LATTEC I/S , CHEN, Fei , MØLLER, Ann, Merete
发明人： CHEN, Fei , MØLLER, Ann, Merete
IPC分类号： G01N33/558
CPC分类号： G01N33/558 , G01N33/743 , G01N33/746
摘要： A device for assaying a steroid compound in a liquid sample is provided. The device comprises a porous zone permitting the migration of the liquid sample. The said porous zone comprises a first zone, a second zone and a third zone. The first zone comprising a first non-immobilised conjugate, capable of specifically binding to the steroid to be assayed and a second non-immobilised conjugate capable of binding specifically to a compound different from the steroid to be assayed. The second zone comprises the same type of steroid as the one to be assayed which is being immobilised to the porous zone. The third zone comprising the second member of the reference pair to the second conjugate.
摘要翻译：提供了用于测定液体样品中类固醇化合物的装置。该装置包括允许液体样品迁移的多孔区域。所述多孔区包括第一区，第二区和第三区。所述第一区包括能够特异性结合要测定的类固醇的第一非固定化缀合物和能够特异性结合待测定类固醇的化合物的第二非固定化结合物。第二区包含与要测定的类固醇相同类型的类固醇，其被固定在多孔区上。所述第三区域包括与所述第二共轭物的参考对的第二成员。

5. 发明申请

WO2010053383A1 OPTOELECTRONIC COMPONENTS 审中-公开
标题翻译：光电组件
公开(公告)号：WO2010053383A1
公开(公告)日：2010-05-14
申请号：PCT/NZ2009/000240
申请日：2009-11-06
申请人： AUCKLAND UNISERVICES LIMITED , CHEN, Fei , SALCIC, Zoran , GAO, Wei
发明人： CHEN, Fei , SALCIC, Zoran , GAO, Wei
IPC分类号： H03K19/14 , H01L33/00 , G11C11/42 , G02F3/00 , H01L33/28
CPC分类号： H05B33/145
摘要： An optoelectronic component comprising a light emitting structure that is configured to generate light in response to a voltage signal within a predetermined range, the predetermined range having a lower limit and upper limit; a primary input for receiving a source voltage signal that is applied to the light emitting structure; at least one secondary input for receiving an input signal and, in response to the input signal, providing a control voltage signal that is applied to the light emitting structure; and an output for providing an optical output signal on the basis of light generated by the light emitting structure, such that where the source voltage signal and control voltage signal combine to provide an overall voltage signal within the predetermined range, the light emitting structure generates light for driving the optical output signal. Additionally optical/electrical hybrid processors and methods for signal processing.
摘要翻译：一种光电子部件，包括发光结构，其被配置为响应于预定范围内的电压信号而产生光，所述预定范围具有下限和上限; 用于接收施加到发光结构的源极电压信号的主要输入端; 用于接收输入信号的至少一个次级输入端，并且响应于输入信号，提供施加到发光结构的控制电压信号; 以及输出，用于基于由发光结构产生的光提供光输出信号，使得当源电压信号和控制电压信号组合以提供在预定范围内的总电压信号时，发光结构产生光用于驱动光输出信号。另外光/电混合处理器和信号处理方法。

6. 发明申请

WO2009110806A1 OPTOELECTRONIC LIGHT EMITTING STRUCTURE 审中-公开
标题翻译：光电发光结构
公开(公告)号：WO2009110806A1
公开(公告)日：2009-09-11
申请号：PCT/NZ2009/000028
申请日：2009-03-05
申请人： AUCKLAND UNISERVICES LIMITED , SALCIC, Zoran , CHEN, Fei , GAO, Wei , CHEONG, Wong, Chee , CHOLLET, Franck
发明人： SALCIC, Zoran , CHEN, Fei , GAO, Wei , CHEONG, Wong, Chee , CHOLLET, Franck
IPC分类号： H05B33/10 , H01L33/00 , H05B33/12
CPC分类号： H05B33/18 , H05B33/145 , H05B33/20
摘要： A light emitting structure comprising a hot electron source and a layer of ptoelectronic material disposed thereon and optionally p-type material disposed on the optoelectronic material. For example, a light emitting structure that comprises, in order, a polycrystalline silicon layer, a silicon dioxide layer, a zinc oxide layer and an indium tin oxide (ITO) layer. When a sufficient voltage is applied across the layers, light is generated.
摘要翻译：一种发光结构，包括热电子源和设置在其上的电子材料层，以及可选地配置在光电子材料上的p型材料。例如，依次包括多晶硅层，二氧化硅层，氧化锌层和氧化铟锡（ITO）层的发光结构。当跨层施加足够的电压时，产生光。

7. 发明申请

WO2008144963A1 PHOTODEGRADATION CATALYST AND PHOTODEGRADATION CATALYST PRECURSOR COMPRISING METAL HALIDE OR METAL OXYHALIDE 审中-公开
标题翻译：光催化催化剂和光催化催化剂前体包含金属卤化物或金属氧化物
公开(公告)号：WO2008144963A1
公开(公告)日：2008-12-04
申请号：PCT/CN2007/001753
申请日：2007-06-01
申请人： MICROVAST, INC. , ZHOU, Xiao Ping , CHEN, Fei , XU, Jeff Qiang
发明人： ZHOU, Xiao Ping , CHEN, Fei , XU, Jeff Qiang
IPC分类号： B01J27/06 , B01J21/00 , B01J23/00 , B01J37/04
CPC分类号： B01J35/004 , B01D53/8668 , B01D2251/102 , B01D2251/11 , B01D2255/2027 , B01D2255/204 , B01D2255/2047 , B01D2255/206 , B01D2255/20723 , B01D2255/802 , B01D2257/7027 , B01D2257/704 , B01D2259/802 , B01D2259/804 , B01J23/10 , B01J23/20 , B01J23/22 , B01J23/28 , B01J23/6482 , B01J27/08 , B01J27/12 , B01J35/002 , B01J37/03 , B01J37/22
摘要： A photodegradation catalyst or a photodegradation catalyst precursor comprises a plurality of domains of an oxide of a first metal distributed in a substrate of a halide or oxyhalide of a second metal, wherein the mole percentage of the halide or oxyhalide of the second metal is above 50%. Additionally, a method of preparing a photodegradation catalyst or a photodegradation catalyst precursor, a photodegradation catalyst or a photodegradation catalyst precursor obtained from the method and a method of treating organic pollutants or substances in air or water by using the photodegradation catalyst or the photodegradation catalyst precursor are illustrated.
摘要翻译：光降解催化剂或光降解催化剂前体包括分布在第二金属的卤化物或卤氧化物的基底中的第一金属的氧化物的多个结构域，其中第二金属的卤化物或卤氧化物的摩尔百分比高于50 ％。另外，通过使用光降解催化剂或光降解催化剂前体的方法和通过空气或水中的有机污染物或物质处理的方法获得的光降解催化剂或光降解催化剂前体，光降解催化剂或光降解催化剂前体的制备方法，被说明。

8. 发明申请

WO2004025301A1 DEVICE FOR ANALYSING ANALYTE COMPOUNDS AND USE HEREOF 审中-公开
标题翻译：用于分析分析化合物的装置，并在此使用
公开(公告)号：WO2004025301A1
公开(公告)日：2004-03-25
申请号：PCT/DK2003/000586
申请日：2003-09-11
申请人： LATTEC I/S , CHEN, Fei , MØLLER, Ann, Merete
发明人： CHEN, Fei , MØLLER, Ann, Merete
IPC分类号： G01N33/558
CPC分类号： G01N33/558 , G01N33/54353 , G01N33/544 , G01N33/743
摘要： An analytical device consisting of porous material(s) that permit(s) liquid to migrate therein, the device comprising in the migration direction. The device comprises a first zone onto which a sample suspected of containing an analyte to be assayed can be applied, a second zone incorporating a non-immobilised molecule capable of specifically binding to the analyte, said molecule is provided with a detectable label, a third zone capable of retarding the rate of migration of the sample and the non-immobilised molecule, and a fourth zone incorporating in at least part of the zone an immobilised state the same type of analyte as the one to be assayed or an analogue thereof being capable of specifically binding to the non-immobilised molecule.
摘要翻译：由允许液体迁移到其中的多孔材料组成的分析装置，该装置包括沿迁移方向。所述装置包括第一区，其上可以应用怀疑含有要测定的分析物的样品，含有能够特异性结合分析物的非固定化分子的第二区，所述分子具有可检测标记，第三区能够延缓样品和非固定化分子的迁移速率的区域，以及将至少部分该区域的固定化状态的第四区域与待测定的相同类型的分析物或其类似物能够特异性结合非固定化分子。

9. 发明申请

WO2018191942A1 PROCESS FOR PRODUCING FLEXIBLE CONTAINERS 审中-公开
公开(公告)号：WO2018191942A1
公开(公告)日：2018-10-25
申请号：PCT/CN2017/081399
申请日：2017-04-21
申请人： DOW GLOBAL TECHNOLOGIES LLC , CHEN, Fei , LI, Bin , PENG, Xun De
发明人： CHEN, Fei , LI, Bin , PENG, Xun De
IPC分类号： B65B51/10 , B65B61/06
摘要： A process for producing a flexible container is provided and includes: A. providing a heat seal apparatus having a first seal plate structure comprising a movable blade member and an opposing second seal plate structure comprising a channel aligned with the blade member, and a bumper member located in the channel; B. placing a continuous web between the seal plate structures, the web comprising a plurality of multilayer films; C. moving the blade member from a retracted position to an extended position; D. cutting the continuous web with the blade member; and E. contacting the bumper member with a cutting edge of the blade member, when the blade member is in the extended position. The process can reduce wear and damage to the cutting element of the heat seal apparatus.

10. 发明申请

WO2008036550A2 SELF-CALIBRATING FRAUD DETECTION 审中-公开
标题翻译：自我校准欺诈检测
公开(公告)号：WO2008036550A2
公开(公告)日：2008-03-27
申请号：PCT/US2007/078415
申请日：2007-09-13
申请人： FAIR ISAAC CORPORATION , ZOLDI, Scott M. , WU, Steven , CHEN, Fei
发明人： ZOLDI, Scott M. , WU, Steven , CHEN, Fei
IPC分类号： G06Q40/00
CPC分类号： G06Q40/02 , G06Q40/00
摘要： A method for dynamically updating a model is described. The method includes accessing a model that specifies expected characteristics for a transaction. The model includes variables associated with fraud. The method also includes receiving at least one value for each of the variables while monitoring transactions, and updating a distribution of values for each variable based on the received value. The received value is compared with the updated distribution to determine a deviation from a threshold value associated with a percentile of the updated distribution that is indicative of fraud.
摘要翻译：描述了用于动态更新模型的方法。该方法包括访问指定交易预期特征的模型。该模型包含与欺诈相关的变量。该方法还包括在监视交易时接收每个变量的至少一个值，并基于接收到的值更新每个变量的值的分布。将所接收的值与更新后的分布进行比较，以确定与指示欺诈的更新分布的百分位相关的阈值的偏差。

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