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    • 3. 发明申请
    • THE USE OF N-ARYLHYDRAZINE DERIVATIVES FOR COMBATING PESTS IN AND ON ANIMALS
    • N-芳基肼衍生物在动物中和动物中的应用
    • WO2005053402A2
    • 2005-06-16
    • PCT/EP2004/013685
    • 2004-12-02
    • BASF AKTIENGESELLSCHAFTVON DEYN, WolfgangOLOUMI-SADEGHI, HassanKUHN, David G.ARMES, NigelKORADIN, ChristopherZELLER, Alissa
    • VON DEYN, WolfgangOLOUMI-SADEGHI, HassanKUHN, David G.ARMES, NigelKORADIN, ChristopherZELLER, Alissa
    • A01N37/00
    • A01N37/52
    • Use of compounds of formula (I) wherein Q is (II), (III), or (IV) ; X 1 is chlorine, bromine, or fluorine; R 1 , R 2 are each independently H, alkyl, alkenyl, alkynyl, or cycloalkyl, alkylamino, dialkylamino, alkylcarbonylamino, alkylsulfonyl, or alkylsulfinyl, wherein the carbon atoms in these groups may be substituted, or R 1 and R 2 may be taken together to form a ring represented by the structure (V); p,m are 1, 2 or 3; X' is oxygen, sulfur, amino, alkylamino, phenylamino, or methylene; Z is alkyl or phenyl; R 3 is H, alkyl, alkenyl, alkynyl, cycloalkyl, wherein the carbon atoms in these groups may be substituted; R, R 4 are H or alkyl, alkoxycarbonyl, alkylaminocarbonyl, or dialkylaminocarbonyl, wherein the carbon atoms in the these groups may be substituted; A is C-R 5 or N; B is C-R 6 or N; W is C-R 7 or N; with the proviso that one of A, B and W is other than N; R 5 , R 6 , R 7 are H, halogen, nitro, cyano, amino, mercapto, hydroxy, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkylsulfonyl, or alkylsulfinyl, wherein the carbon atoms in these groups may be substituted, a 5- to 6-membered aromatic ringsystem which may contain 1 to 4 heteroatoms selected from oxygen, sulfur and nitrogen and which may be substituted; Y is hydrogen, halogen, cyano, nitro, amino, hydroxy, mercapto, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkylsulfonyl, or alkylsulfinyl, wherein the carbon atoms in these groups may be substituted; n is 0, 1, or 2; for combating parasites in and on animals.
    • 其中Q是(II),(III)或(IV)的式(I)化合物的用途; X 1是氯,溴或氟; R 1,R 2各自独立地为H,烷基,烯基,炔基或环烷基,烷基氨基,二烷基氨基,烷基羰基氨基,烷基磺酰基或烷基亚磺酰基,其中这些中的碳原子 基团可以被取代,或者R 1和R 2可以一起形成由结构(V)表示的环; p,m是1,2或3; X'是氧,硫,氨基,烷基氨基,苯基氨基或亚甲基; Z是烷基或苯基; R 3是H,烷基,烯基,炔基,环烷基,其中这些基团中的碳原子可以被取代; R,R 4为H或烷基,烷氧基羰基,烷基氨基羰基或二烷基氨基羰基,其中这些基团中的碳原子可以被取代; A是C-R 5或N; B是C-R 6或N; W是C-R 7或N; 条件是A,B和W中的一个不是N; R 5,R 6,R 7为H,卤素,硝基,氰基,氨基,巯基,羟基,烷基,链烯基,炔基, 环烷基,烷氧基,烷基氨基,二烷基氨基,烷硫基,烷基磺酰基或烷基亚磺酰基,其中这些基团中的碳原子可被取代,可含有1-4个选自氧,硫和氮的杂原子的5-6元芳族环体系和 它可以被替代; Y是氢,卤素,氰基,硝基,氨基,羟基,巯基,烷基,烯基,炔基,环烷基,烷氧基,烷基氨基,二烷基氨基,烷硫基,烷基磺酰基或烷基亚磺酰基,其中这些基团中的碳原子可以被取代; n是0,1或2; 打击动物体内和体内的寄生虫。
    • 6. 发明申请
    • AMIDRAZONE COMPOUNDS FOR COMBATING ANIMAL PESTS
    • 用于组合动物疫苗的咪唑烷化合物
    • WO2006097279A1
    • 2006-09-21
    • PCT/EP2006/002331
    • 2006-03-14
    • BASF AKTIENGESELLSCHAFTKORADIN, ChristopherVON DEYN, WolfgangRACK, MichaelKUHN, David, G.CULBERTSON, Deborah, L.ANSPAUGH, DouglasOLOUMI-SADEGHI, Hassan
    • KORADIN, ChristopherVON DEYN, WolfgangRACK, MichaelKUHN, David, G.CULBERTSON, Deborah, L.ANSPAUGH, DouglasOLOUMI-SADEGHI, Hassan
    • A01N37/52C07C259/20A01P7/00A01P5/00A01P7/04
    • C07C259/20A01N37/52C07C2601/02
    • The present invention relates to new amidrazone compounds which are useful for combating animal pests, in particular insects, arachnids and nematodes. The invention also relates to a method for combating insects, nematodes and arachnids. The amidrazone compounds are of the general formula (I) including the tautomers of I and the salts thereof; wherein X and Y are hydrogen or together form a chemical bond; Ar is an aromatic radical selected from phenyl and a 5- or 6-membered heteroaryl having 1 , 2, 3 or 4 heteroatoms as ring members, which are selected, independently of one another, from O, N and S, and where the aromatic radical may have 1 , 2, 3, 4 or 5 substituents R a ; R 1 is selected from the group consisiting of C 1 -C 1O -alkyl, C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, cyano-C 1 -C 4 -alkyl, hydroxy-C 1- C 4 -alkyl, C 1 -C 10 -haloalkyl, tri-(C 1 -C 4 -alkyl)-silyl-C 1 - C 4 -alkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl, C 2 -C 10 -alkynyl, C 2 -C 10 -haloalkynyl, C 3 -C 10 -cycloalkyl, phenyl, heteroaryl, C 3 -C 10 -cycloalkyl-C 1 C 4 -alkyl, phenyl-C 1 -C 4 - alkyl and heteroaryl-C 1 C 4 alkyl, wherein C 3 -C 10 -cycloalkyl, heteroaryl and phenyl in the last six mentioned radicals may be unsubstituted or carry 1 , 2, 3, 4 or 5 substituents R b as defined above; R 2 is selected from the group consisiting of C 1- C 1 0-alkyl, c 1- c 4 -alkoxy- C 1- C 4 -alkyl, C 1- C 10 -haloalkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl, C 2 -C 10 -alkynyl, C 2 -C 10 - haloalkynyl,c 3 -C 10 -cycloalkyl, phenyl, heteroaryl, C 3 -C 10 -cycloalkyl-C 1- C 4 -alkyl, phenyl-C 1 -C 4 -alkyl and heteroaryI-C 1- C 4 -alkyl, wherein C 3 -C 10 -cycloalkyl, heteroaryl and phenyl in the last six mentioned radicals may be unsubstituted or carry 1 , 2, 3, 4 or 5 substituents R b as defined above.
    • 本发明涉及可用于对抗动物害虫,特别是昆虫,蜘蛛和线虫的新的氨基腙化合物。 本发明还涉及一种防治昆虫,线虫和蜘蛛的方法。 氨基腙化合物具有通式(I),其包括I的互变异构体及其盐; 其中X和Y是氢或一起形成化学键; Ar是选自苯基和具有1,2,3或4个杂原子作为环成员的5-或6-元杂芳基的芳族基团,其彼此独立地选自O,N和S,并且其中芳族 基团可以具有1,2,3,4或5个取代基R a, R 1选自C 1 -C 10 - 烷基,C 1 -C 1 - 烷基, C 1 -C 4烷基,C 1 -C 4烷基,C 1 -C 4烷基,氰基-C 1 -C 4烷基, C 1 -C 6烷基,羟基-C 1 -C 4 - 亚烷基,C 1 -C 10 - 烷基, 卤代烷基,三 - (C 1 -C 4 - 烷基) - 甲硅烷基-C 1 -C 4 - 烷基,C 2 -C 10 - 烯基,C 2 -C 10 - 卤代烯基,C 1 -C 10 - C 2 -C 10 - 炔基,C 2 -C 10 - 卤代炔基,C 3 - C 10 - 环烷基,苯基,杂芳基,C 3 -C 10 - 环烷基-C 1 -C C 1-4烷基,苯基-C 1 -C 4 - 烷基和杂芳基-C 1 -C 4烷基, 其中C 3 -C 10 - 环烷基,杂芳基和苯基在后面六个提及的基团中可以是未取代的或携带1,2,3,4或4个 5个取代基R b如上所定义; R 2选自C 1 -C 1-4烷基,C 1 -C 4烷基, C 1-4烷基,C 1 -C 10烷基,C 1 -C 4烷基,C 1〜 亚烷基,C 2 -C 10 - 烯基,C 2 -C 10 - 卤代烯基,C C 2 -C 10 - 炔基,C 2 -C 10 - 卤代炔基,C 3 - C 1 -C 10 - 环烷基,苯基,杂芳基,C 3 -C 10 - 环烷基-C 1 - C 1 -C 4 - 烷基,苯基-C 1 -C 4 - 烷基和杂芳基C 1 -C 其中C 3 -C 10 - 环烷基,最后六个所述基团中的杂芳基和苯基可以是未取代的或携带1, 2,3,4或5个如上定义的取代基R b。
    • 8. 发明申请
    • PESTICIDAL MIXTURE
    • 杀菌混合物
    • WO2006128863A1
    • 2006-12-07
    • PCT/EP2006/062714
    • 2006-05-30
    • BASF AktiengesellschaftANSPAUGH, Douglas D.ARMES, NigelKUHN, David G.OLOUMI-SADEGHI, Hassan
    • ANSPAUGH, Douglas D.ARMES, NigelKUHN, David G.OLOUMI-SADEGHI, Hassan
    • A01N37/52A01P7/00A01N53/00A01N51/00A01N47/34
    • A01N37/52A01N2300/00
    • Pesticidal mixtures comprising, as active components 1 ) a compound of the formula I wherein W is CI or CF 3 ; X and Y are each independently CI or Br; R 1 is alkyl, alkenyl, alkynyl, or cycloalkyl optionally substituted with 1 to 3 halogens, or alkyl which is substituted by alkoxy; R 2 and R 3 are alkyl or may be taken together to form cycloalkyl optionally substituted by 1 to 3 halogens; R 4 is H or C 1 -C 8 -alkyl, or the enantiomers or salts thereof, and a Compound II selected from organo(thio)phosphates, carbamates, pyrethroids, growth regulators, nicotinic receptor agonists/antagonists Compounds, GABA antagonist compounds, macrocyclic lactone insecticides, METI I acaricides, METI II and III compounds, uncoupler compounds, oxidative phosphorylation inhibitor compounds, moulting disruptor compounds, mixed function oxidase inhibitor compounds, sodium channel blocker compounds, and other various pesticide compounds. In synergistically effective amounts, methods for the control of insects or acarids by contacting them or their food suppiy, habitat, breeding grounds or their locus with mixtures of the compound I with a compound II, a method of protecting plants from attack or infestation by insects or acarids employing mixtures of the compound I with a compound II, and a process for the preparation of a composition for treating, controlling, preventing or protecting a warm-blooded animal or a fish against infestation or infection by insects or acarids which comprises a pesticidally effective amount of a mixture of the compound I with a compound II.
    • 包含作为活性组分的农药混合物1)式I化合物,其中W是Cl或CF 3; X和Y各自独立地为Cl或Br; R 1是任选被1至3个卤素取代的烷基,烯基,炔基或环烷基,或被烷氧基取代的烷基; R 2和R 3是烷基或可以一起形成任选被1至3个卤素取代的环烷基; R 4是H或C 1 -C 8 - 烷基,或其对映异构体或盐,和选自有机(硫代) )磷酸盐,氨基甲酸盐,拟除虫菊酯,生长调节剂,烟碱受体激动剂/拮抗剂化合物,GABA拮抗剂化合物,大环内酯杀虫剂,METI I杀螨剂,METI II和III化合物,解偶联剂化合物,氧化磷酸化抑制剂化合物,蜕皮破坏剂化合物,混合功能氧化酶 抑制剂化合物,钠通道阻断剂化合物等各种农药化合物。 通过协同有效的量,通过将化合物I与化合物II的混合物接触或控制昆虫或螨的食物,栖息地,繁殖地或其位点与昆虫或螨虫的控制方法,保护植物免受昆虫侵袭或侵袭的方法 或使用化合物I与化合物II的混合物的吖啶,以及制备用于治疗,控制,预防或保护温血动物或鱼类以防止昆虫或螨虫侵染或感染的组合物的方法,其包括农药 有效量的化合物I与化合物II的混合物。
    • 10. 发明申请
    • PESTICIDAL MIXTURES
    • 农药混合物
    • WO2007082841A2
    • 2007-07-26
    • PCT/EP2007/050280
    • 2007-01-12
    • BASF AKTIENGESELLSCHAFTGEWEHR, MarkusPUHL, MichaelDICKHAUT, JoachimBASTIAANS, Henricus Maria MartinusANSPAUGH, Douglas D.KUHN, David G.OLOUMI-SADEGHI, HassanARMES, Nigel
    • GEWEHR, MarkusPUHL, MichaelDICKHAUT, JoachimBASTIAANS, Henricus Maria MartinusANSPAUGH, Douglas D.KUHN, David G.OLOUMI-SADEGHI, HassanARMES, Nigel
    • A01N43/56A01N2300/00
    • Pesticidal mixtures comprising, as active components, 1 ) an anthranilamid compound of the formula I wherein Q is H, Cl, Cr, I, CN or methyl; B 1 is halogen, alkyl, haloalkyl, or haloalkoxy; B 2 is halogen, haloalkyl, alkoxy, haloalkoxy, alkenyloxy, alkynyloxy, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, alkyl- S(=O) x -O- or haloalkyl S(O) x -O-, wherein x is 1 or 2 and the alkoxy radical may be substituted, or C(R i )=N-OR j , C(R i )=N(R j R k ), wherein R i , R j and R k are hydrogen or alkyl; R is hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, alkylene-cycloalkyl, wherein these groups are optionally substituted; R 1 is F, CI, Br, methyl or trifluoromethyl; or the enantiomers or salts or N-oxides thereof, n is 1 , 2 or 3; and 2) one or more compounds II selected from group A consisting of organo(thio)- phosphates, carbamates, pyrethroids, growth regulators, nicotinic receptor agonists/antagonists compounds, GABA antagonist compounds, macrocyclic lactone insecticides, METI I acaricides, METI II and III compounds, uncoupler compounds, oxidative phosphorylation inhibitor compounds, mixed function oxidase inhibitor compounds, sodium channel blocker compounds and others, all as defined in the description, in synergistically effective amounts, use of these mixture for combating insects, arachnids or nematodes in and on plants and for the protection of seeds, and for treating, controlling, preventing or protecting a warm-blooded animal or a fish against infestation or infection by parasites.
    • 作为活性组分的农药混合物,1)式I的氨基甲酰胺化合物,其中Q是H,Cl,Cr,I,CN或甲基; B 1是卤素,烷基,卤代烷基或卤代烷氧基; B 2是卤素,卤代烷基,烷氧基,卤代烷氧基,烯氧基,炔氧基,烷硫基,卤代烷硫基,烷基亚磺酰基,卤代烷基亚磺酰基,烷基磺酰基,卤代烷基磺酰基,烷基-S(= O) O-或卤代烷基S(O)x -O-,其中x为1或2,烷氧基可以被取代,或C(R i)= N- C(R i,R i)= N(R i,R k)),其中R 0, R i,R j和R k都是氢或烷基; R是氢,烷基,烯基,炔基,环烷基,亚烷基 - 环烷基,其中这些基团是任选取代的; R 1是F,Cl,Br,甲基或三氟甲基; 或其对映异构体或其盐或N-氧化物,n为1,2或3; 和2)一种或多种选自有机(硫代) - 磷酸酯,氨基甲酸酯,拟除虫菊酯,生长调节剂,烟碱受体激动剂/拮抗剂化合物,GABA拮抗剂化合物,大环内酯杀虫剂,METI I杀螨剂,METI II和 III化合物,非偶联剂化合物,氧化磷酸化抑制剂化合物,混合功能氧化酶抑制剂化合物,钠通道阻断剂化合物和其他,如描述中所定义的,协同有效量的这些混合物用于对抗昆虫,蜘蛛或线虫 植物和保护种子,以及用于治疗,控制,预防或保护温血动物或鱼类免受寄生虫感染或感染。