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    • 1. 发明申请
    • THE USE OF N-ARYLHYDRAZINE DERIVATIVES FOR COMBATING PESTS IN AND ON ANIMALS
    • N-芳基肼衍生物在动物中和动物中的应用
    • WO2005053402A2
    • 2005-06-16
    • PCT/EP2004/013685
    • 2004-12-02
    • BASF AKTIENGESELLSCHAFTVON DEYN, WolfgangOLOUMI-SADEGHI, HassanKUHN, David G.ARMES, NigelKORADIN, ChristopherZELLER, Alissa
    • VON DEYN, WolfgangOLOUMI-SADEGHI, HassanKUHN, David G.ARMES, NigelKORADIN, ChristopherZELLER, Alissa
    • A01N37/00
    • A01N37/52
    • Use of compounds of formula (I) wherein Q is (II), (III), or (IV) ; X 1 is chlorine, bromine, or fluorine; R 1 , R 2 are each independently H, alkyl, alkenyl, alkynyl, or cycloalkyl, alkylamino, dialkylamino, alkylcarbonylamino, alkylsulfonyl, or alkylsulfinyl, wherein the carbon atoms in these groups may be substituted, or R 1 and R 2 may be taken together to form a ring represented by the structure (V); p,m are 1, 2 or 3; X' is oxygen, sulfur, amino, alkylamino, phenylamino, or methylene; Z is alkyl or phenyl; R 3 is H, alkyl, alkenyl, alkynyl, cycloalkyl, wherein the carbon atoms in these groups may be substituted; R, R 4 are H or alkyl, alkoxycarbonyl, alkylaminocarbonyl, or dialkylaminocarbonyl, wherein the carbon atoms in the these groups may be substituted; A is C-R 5 or N; B is C-R 6 or N; W is C-R 7 or N; with the proviso that one of A, B and W is other than N; R 5 , R 6 , R 7 are H, halogen, nitro, cyano, amino, mercapto, hydroxy, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkylsulfonyl, or alkylsulfinyl, wherein the carbon atoms in these groups may be substituted, a 5- to 6-membered aromatic ringsystem which may contain 1 to 4 heteroatoms selected from oxygen, sulfur and nitrogen and which may be substituted; Y is hydrogen, halogen, cyano, nitro, amino, hydroxy, mercapto, alkyl, alkenyl, alkynyl, cycloalkyl, alkoxy, alkylamino, dialkylamino, alkylthio, alkylsulfonyl, or alkylsulfinyl, wherein the carbon atoms in these groups may be substituted; n is 0, 1, or 2; for combating parasites in and on animals.
    • 其中Q是(II),(III)或(IV)的式(I)化合物的用途; X 1是氯,溴或氟; R 1,R 2各自独立地为H,烷基,烯基,炔基或环烷基,烷基氨基,二烷基氨基,烷基羰基氨基,烷基磺酰基或烷基亚磺酰基,其中这些中的碳原子 基团可以被取代,或者R 1和R 2可以一起形成由结构(V)表示的环; p,m是1,2或3; X'是氧,硫,氨基,烷基氨基,苯基氨基或亚甲基; Z是烷基或苯基; R 3是H,烷基,烯基,炔基,环烷基,其中这些基团中的碳原子可以被取代; R,R 4为H或烷基,烷氧基羰基,烷基氨基羰基或二烷基氨基羰基,其中这些基团中的碳原子可以被取代; A是C-R 5或N; B是C-R 6或N; W是C-R 7或N; 条件是A,B和W中的一个不是N; R 5,R 6,R 7为H,卤素,硝基,氰基,氨基,巯基,羟基,烷基,链烯基,炔基, 环烷基,烷氧基,烷基氨基,二烷基氨基,烷硫基,烷基磺酰基或烷基亚磺酰基,其中这些基团中的碳原子可被取代,可含有1-4个选自氧,硫和氮的杂原子的5-6元芳族环体系和 它可以被替代; Y是氢,卤素,氰基,硝基,氨基,羟基,巯基,烷基,烯基,炔基,环烷基,烷氧基,烷基氨基,二烷基氨基,烷硫基,烷基磺酰基或烷基亚磺酰基,其中这些基团中的碳原子可以被取代; n是0,1或2; 打击动物体内和体内的寄生虫。
    • 7. 发明申请
    • AMIDRAZONE COMPOUNDS FOR COMBATING ANIMAL PESTS
    • 用于组合动物疫苗的咪唑烷化合物
    • WO2006097279A1
    • 2006-09-21
    • PCT/EP2006/002331
    • 2006-03-14
    • BASF AKTIENGESELLSCHAFTKORADIN, ChristopherVON DEYN, WolfgangRACK, MichaelKUHN, David, G.CULBERTSON, Deborah, L.ANSPAUGH, DouglasOLOUMI-SADEGHI, Hassan
    • KORADIN, ChristopherVON DEYN, WolfgangRACK, MichaelKUHN, David, G.CULBERTSON, Deborah, L.ANSPAUGH, DouglasOLOUMI-SADEGHI, Hassan
    • A01N37/52C07C259/20A01P7/00A01P5/00A01P7/04
    • C07C259/20A01N37/52C07C2601/02
    • The present invention relates to new amidrazone compounds which are useful for combating animal pests, in particular insects, arachnids and nematodes. The invention also relates to a method for combating insects, nematodes and arachnids. The amidrazone compounds are of the general formula (I) including the tautomers of I and the salts thereof; wherein X and Y are hydrogen or together form a chemical bond; Ar is an aromatic radical selected from phenyl and a 5- or 6-membered heteroaryl having 1 , 2, 3 or 4 heteroatoms as ring members, which are selected, independently of one another, from O, N and S, and where the aromatic radical may have 1 , 2, 3, 4 or 5 substituents R a ; R 1 is selected from the group consisiting of C 1 -C 1O -alkyl, C 1 -C 4 -alkoxy-C 1 -C 4 -alkyl, cyano-C 1 -C 4 -alkyl, hydroxy-C 1- C 4 -alkyl, C 1 -C 10 -haloalkyl, tri-(C 1 -C 4 -alkyl)-silyl-C 1 - C 4 -alkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl, C 2 -C 10 -alkynyl, C 2 -C 10 -haloalkynyl, C 3 -C 10 -cycloalkyl, phenyl, heteroaryl, C 3 -C 10 -cycloalkyl-C 1 C 4 -alkyl, phenyl-C 1 -C 4 - alkyl and heteroaryl-C 1 C 4 alkyl, wherein C 3 -C 10 -cycloalkyl, heteroaryl and phenyl in the last six mentioned radicals may be unsubstituted or carry 1 , 2, 3, 4 or 5 substituents R b as defined above; R 2 is selected from the group consisiting of C 1- C 1 0-alkyl, c 1- c 4 -alkoxy- C 1- C 4 -alkyl, C 1- C 10 -haloalkyl, C 2 -C 10 -alkenyl, C 2 -C 10 -haloalkenyl, C 2 -C 10 -alkynyl, C 2 -C 10 - haloalkynyl,c 3 -C 10 -cycloalkyl, phenyl, heteroaryl, C 3 -C 10 -cycloalkyl-C 1- C 4 -alkyl, phenyl-C 1 -C 4 -alkyl and heteroaryI-C 1- C 4 -alkyl, wherein C 3 -C 10 -cycloalkyl, heteroaryl and phenyl in the last six mentioned radicals may be unsubstituted or carry 1 , 2, 3, 4 or 5 substituents R b as defined above.
    • 本发明涉及可用于对抗动物害虫,特别是昆虫,蜘蛛和线虫的新的氨基腙化合物。 本发明还涉及一种防治昆虫,线虫和蜘蛛的方法。 氨基腙化合物具有通式(I),其包括I的互变异构体及其盐; 其中X和Y是氢或一起形成化学键; Ar是选自苯基和具有1,2,3或4个杂原子作为环成员的5-或6-元杂芳基的芳族基团,其彼此独立地选自O,N和S,并且其中芳族 基团可以具有1,2,3,4或5个取代基R a, R 1选自C 1 -C 10 - 烷基,C 1 -C 1 - 烷基, C 1 -C 4烷基,C 1 -C 4烷基,C 1 -C 4烷基,氰基-C 1 -C 4烷基, C 1 -C 6烷基,羟基-C 1 -C 4 - 亚烷基,C 1 -C 10 - 烷基, 卤代烷基,三 - (C 1 -C 4 - 烷基) - 甲硅烷基-C 1 -C 4 - 烷基,C 2 -C 10 - 烯基,C 2 -C 10 - 卤代烯基,C 1 -C 10 - C 2 -C 10 - 炔基,C 2 -C 10 - 卤代炔基,C 3 - C 10 - 环烷基,苯基,杂芳基,C 3 -C 10 - 环烷基-C 1 -C C 1-4烷基,苯基-C 1 -C 4 - 烷基和杂芳基-C 1 -C 4烷基, 其中C 3 -C 10 - 环烷基,杂芳基和苯基在后面六个提及的基团中可以是未取代的或携带1,2,3,4或4个 5个取代基R b如上所定义; R 2选自C 1 -C 1-4烷基,C 1 -C 4烷基, C 1-4烷基,C 1 -C 10烷基,C 1 -C 4烷基,C 1〜 亚烷基,C 2 -C 10 - 烯基,C 2 -C 10 - 卤代烯基,C C 2 -C 10 - 炔基,C 2 -C 10 - 卤代炔基,C 3 - C 1 -C 10 - 环烷基,苯基,杂芳基,C 3 -C 10 - 环烷基-C 1 - C 1 -C 4 - 烷基,苯基-C 1 -C 4 - 烷基和杂芳基C 1 -C 其中C 3 -C 10 - 环烷基,最后六个所述基团中的杂芳基和苯基可以是未取代的或携带1, 2,3,4或5个如上定义的取代基R b。