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    • 1. 发明申请
    • METHODS AND APPARATUSES FOR SEPARATING BIOLOGICAL PARTICLES
    • 分离生物颗粒的方法和装置
    • WO2008148028A3
    • 2009-02-05
    • PCT/US2008064747
    • 2008-05-23
    • APPLERA CORPLIU YINGJIE
    • LIU YINGJIE
    • C12N5/06C12N5/00
    • B03C1/32B01L3/502753B01L2400/0409B01L2400/043B01L2400/0487G01N1/4055G01N2001/4072
    • Methods and apparatuses for separating biological particles are provided In certain embodiments the separation apparatus is utilized for separating first biological particles from second biological particles under flow conditions, and comprises (a) a separation region, b) a first inlet port operably connected to a first end of the separation region, c) a second inlet port operably connected to the first end of the separation region, d) two or more posts aligned along a plane extending along a diagonal axis from the first end of the separation region to a second end of the separation region In certain embodiments, the spacing between adjacent posts is such that a first biological particle can pass between the posts but a second biological particle cannot pass between the posts.
    • 提供用于分离生物颗粒的方法和装置在某些实施方案中,分离装置用于在流动条件下从第二生物颗粒分离第一生物颗粒,并且包括(a)分离区域,b)可操作地连接到第一生物颗粒的第一入口 c)可操作地连接到分离区域的第一端的第二入口端口,d)沿着从分离区域的第一端部延伸的对角轴线的平面对准的两个或更多个柱体, 在某些实施方案中,相邻柱之间的间距使得第一生物颗粒可以在柱之间通过,但是第二生物颗粒不能在柱之间通过。