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1. 发明申请

WO2014197334A3 SYSTEM AND METHOD FOR USER-SPECIFIED PRONUNCIATION OF WORDS FOR SPEECH SYNTHESIS AND RECOGNITION 审中-公开
标题翻译：用于用户指定的语音合成和识别词汇的系统和方法
公开(公告)号：WO2014197334A3
公开(公告)日：2015-01-29
申请号：PCT/US2014040393
申请日：2014-05-30
申请人： APPLE INC , NAIK DEVANG K , WEINER LIAM , BINDER JUSTIN G , SRISUWANANUKORN CHARLES , EVERMANN GUNNAR , WILLIAMS SHAUN , CHEN HONG , NAPOLITANO LIA T
发明人： NAIK DEVANG K , WEINER LIAM , BINDER JUSTIN G , SRISUWANANUKORN CHARLES , EVERMANN GUNNAR , WILLIAMS SHAUN , CHEN HONG , NAPOLITANO LIA T , GRUBER THOMAS R
IPC分类号： G10L13/00 , G10L13/04 , G10L15/22 , G10L15/26
CPC分类号： G10L13/027 , G10L13/04 , G10L13/08 , G10L15/063 , G10L15/22 , G10L15/26 , G10L15/265 , G10L2015/0631 , G10L2015/0638
摘要： The method is performed at an electronic device with one or more processors and memory storing one or more programs for execution by the one or more processors. A first speech input including at least one word is received. A first phonetic representation of the at least one word is determined, the first phonetic representation comprising a first set of phonemes selected from a speech recognition phonetic alphabet. The first set of phonemes is mapped to a second set of phonemes to generate a second phonetic representation, where the second set of phonemes is selected from a speech synthesis phonetic alphabet. The second phonetic representation is stored in association with a text string corresponding to the at least one word.
摘要翻译：该方法在具有一个或多个处理器的电子设备中执行，存储器存储一个或多个程序以供一个或多个处理器执行。接收包括至少一个字的第一语音输入。确定所述至少一个单词的第一语音表示，所述第一语音表示包括从语音识别语音字母表中选择的第一组音素。将第一组音素映射到第二组音素以产生第二语音表示，其中从语音合成语音字母表中选择第二组音素。第二语音表示与对应于至少一个单词的文本串相关联地存储。

2. 发明申请

WO2012106313A2 UBIQUITIN INTERACTING MOTIF PEPTIDES AS CANCER THERAPEUTICS 审中-公开
标题翻译： UBIQUITIN相互作用的细胞因子作为癌症治疗
公开(公告)号：WO2012106313A2
公开(公告)日：2012-08-09
申请号：PCT/US2012023286
申请日：2012-01-31
申请人： OKLAHOMA MED RES FOUND , DONG YUNZHOU , CHEN HONG
发明人： DONG YUNZHOU , CHEN HONG
IPC分类号： A61K38/17 , A61K38/20 , A61K39/395 , A61N5/00 , A61P9/00 , A61P35/00
CPC分类号： C07K16/18 , A01K67/0276 , A01K2217/075 , A01K2217/15 , A01K2217/203 , A01K2217/206 , A01K2227/105 , A01K2267/0331 , A61K38/00 , A61N2005/1098 , C07K14/4702
摘要： The present invention involves the use peptides comprising ubiquitin interacting motifs (UIMs) alone or in combination with other agents to treat diseases involving neovascularization, such as cancer.
摘要翻译：本发明涉及使用包含泛素相互作用基序（UIM）的肽或与其它试剂组合以治疗涉及新血管形成的疾病如癌症的肽。

3. 发明申请

WO2005056771A3 IN VITRO UPTAKE OF SPAM 1 (PH-20) BY MAMMALIAN SPERM 审中-公开
标题翻译：通过MAMMALIAN SPERM进行垃圾邮件1（PH-20）的体外摄取
公开(公告)号：WO2005056771A3
公开(公告)日：2007-01-18
申请号：PCT/US2004041875
申请日：2004-12-09
申请人： UNIV DELAWARE , DELEON PATRICIA A , CHEN HONG , ZHANG HONG , GRIFFITHS GENEVIEVE S
发明人： DELEON PATRICIA A , CHEN HONG , ZHANG HONG , GRIFFITHS GENEVIEVE S
IPC分类号： A01N1/02 , A01K67/027 , A61K38/00 , C12N20060101 , C12N5/00 , C12N5/076 , C12N9/26
CPC分类号： A01K67/0276 , A01K2217/075 , A01K2227/105 , A01K2267/03 , C12N5/0006 , C12N5/061 , C12N9/2408 , Y10S530/852
摘要： The invention relates to the in vitro transfer of the Sperm Adhesion Molecule 1 (SPAM 1) to spermatozoa. The SPAM1 protein can be obtained from the epididmys or the uterus and should have an intact lipid anchor. The SPAM 1 protein attaches to the surface of mammalian spermatozoa via it's lipid anchor in an in vitro environment in order to increase the sperm's capability of fertilizing an egg.
摘要翻译：本发明涉及将精子粘附分子1（SPAM 1）体外转移至精子。 SPAM1蛋白可以从附睾或子宫获得，并应具有完整的脂质锚。 SPAM 1蛋白通过体外环境中的脂质锚定在哺乳动物精子的表面附着，以增加精子对卵的施肥能力。

4. 发明申请

WO0134773A9 METHODS AND COMPOSITIONS FOR DIAGNOSING AND TREATING CHROMOSOME 18q RELATED DISORDERS 审中-公开
标题翻译：用于诊断和治疗18q相关疾病的方法和组合物
公开(公告)号：WO0134773A9
公开(公告)日：2002-05-23
申请号：PCT/US0030851
申请日：2000-11-08
申请人： MILLENNIUM PHARM INC , UNIV CALIFORNIA , CHEN HONG , FREIMER NELSON B
发明人： CHEN HONG , FREIMER NELSON B
IPC分类号： C12Q1/68 , A61K31/00 , A61K38/00 , C07H21/04 , C07K1/00 , C07K2/00 , C07K16/00 , C12N1/20 , C12N5/00 , C12N15/09 , C12Q1/00 , C12N21/00
CPC分类号： C12Q1/6883 , C12Q2600/158
摘要： L'invention concerne le gène mammifère fsh27 , qui est un nouveau gène associé à la maladie affective bipolaire (BAD) chez les humains. Elle concerne également des acides nucléiques fsh27 , des molécules d'ADN recombinant, des gènes clonés ou des variants dégénérés desdits gènes, des produits géniques fsh27 et des anticorps ciblant lesdits produits géniques, des vecteurs de clonage contenant les molécules du gène mammifère fsh27 , et des hôtes génétiquement modifiés pouvant exprimer ces molécules. L'invention concerne également des méthodes qui permettent d'identifier des composés modulant l'expression des gènes fsh et des produits géniques, et d'utiliser ces composés comme agents thérapeutiques pour le traitement de troubles associés à fsh27 , tels que les troubles neuropsychiatriques. L'invention concerne en outre des méthodes destinées à l'évaluation diagnostique, au dépistage génétique et au pronostic de troubles associés à fsh27 , par exemple les troubles neuropsychiatriques comme le trouble schizo-affectif, la maladie affective bipolaire ou unipolaire. L'invention concerne enfin des méthodes et compositions servant au traitement desdites affections.

5. 发明申请

WO2014066236A3 AUTOMATIC BACTERIA IDENTIFICATION AND URINE ANALYZER 审中-公开
标题翻译：自动细菌鉴定和尿液分析仪
公开(公告)号：WO2014066236A3
公开(公告)日：2014-08-07
申请号：PCT/US2013065888
申请日：2013-10-21
申请人： SIEMENS HEALTHCARE DIAGNOSTICS , LV DONGJIAO , CHEN HONG
发明人： LV DONGJIAO , CHEN HONG
IPC分类号： G06K9/60
CPC分类号： G06T7/0012 , G01N33/493 , G06K9/00147 , G06T7/11 , G06T7/136 , G06T2207/10056 , G06T2207/20012 , G06T2207/20036 , G06T2207/30024
摘要： Provided in the embodiments of the present invention are an automatic bacteria identification apparatus and method, an automatic detection device, and a urine analyzer. The automatic bacteria identification apparatus comprises: a detection unit for detecting a region part that may contain bacteria in an input image, so as to generate an output image containing said region part; and a classification unit for extracting a feature from the region part detected by said detection unit and identifying whether said region part is bacteria based on said feature, wherein said feature is at least one of the area, area ratio, annularity, aspect ratio, contrast and texture complexity of said region part. By means of the automatic bacteria identification apparatus and method according to the embodiments of the present invention, bacteria can be identified automatically from an input image, thereby obtaining a solution that is effective in aspects of accuracy, cost and time.
摘要翻译：在本发明的实施例中提供了一种自动细菌鉴定装置和方法，自动检测装置和尿液分析器。自动细菌识别装置包括：检测单元，用于检测输入图像中可能含有细菌的区域部分，以产生包含所述区域部分的输出图像; 以及分类单元，用于从由所述检测单元检测到的区域部分中提取特征，并且基于所述特征识别所述区域部分是否是细菌，其中所述特征是面积，面积比，环形度，纵横比，对比度中的至少一个和所述区域部分的纹理复杂性。通过根据本发明的实施方式的自动细菌识别装置和方法，可以从输入图像中自动识别细菌，从而获得在精度，成本和时间方面有效的解决方案。

6. 发明申请

WO2006060922A3 MICROFLUIDIC MICROARRAY ASSEMBLIES AND METHODS OF MANUFACTURING AND USING SAME 审中-公开
标题翻译：微流控微型组件及其制造方法和使用方法
公开(公告)号：WO2006060922A3
公开(公告)日：2007-01-11
申请号：PCT/CA2005001884
申请日：2005-12-12
申请人： UNIV FRASER SIMON , LI PAUL CHI HANG , PENG XING YUE , YU HUA ZHONG , PARAMESWAREN MEENAKSHINATHAN , CHEN HONG , CHOU WA LOK
发明人： LI PAUL CHI HANG , PENG XING YUE , YU HUA ZHONG , PARAMESWAREN MEENAKSHINATHAN , CHEN HONG , CHOU WA LOK
IPC分类号： C40B40/00 , C12Q1/68 , C40B50/14 , G01N1/28 , G01N33/543 , G01N33/552
CPC分类号： G01N33/54386 , B01J19/0046 , B01J2219/00421 , B01J2219/00536 , B01J2219/00585 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00621 , B01J2219/00626 , B01J2219/0063 , B01J2219/00637 , B01J2219/00644 , B01J2219/00659 , B01J2219/00675 , B01J2219/00722 , B01J2219/00725 , B01J2219/00731 , B01J2219/0074 , B01J2219/00743 , B01L3/0293 , B01L3/502707 , B01L2200/025 , B01L2200/16 , B01L2300/0806 , B01L2300/0819 , B01L2300/0877 , B01L2400/0409 , B82Y30/00 , C40B80/00 , G01N35/00069 , Y10T436/11 , Y10T436/117497 , Y10T436/118339 , Y10T436/25 , Y10T436/2575
摘要： The invention encompasses microfluidic microarray assemblies (MMA) and subassemblies and methods for their manufacture and use. In one embodiment, first and second channel plates are provided and are sealingly connected to a test chip in consecutive steps. Each plate includes microfluidic channels configured in a predetermined reagent distribution pattern. The test chip comprises a plurality of discrete test positions, each test position being located at the intersection between a first predetermined reagent pattern and a second predetermined reagent pattern, wherein at least one of said patterns is non-linear. The first channel plate allows the distribution of a first reagent on said test chip, wherein said first reagent is immobilized at said test positions. The second channel plate allows the distribution of a second reagent on said test chip, wherein said second reagent comprises a plurality of different test samples.
摘要翻译：本发明包括微流体微阵列组件（MMA）及其组件及其制造和使用的方法。在一个实施例中，提供第一和第二通道板，并在连续的步骤中密封地连接到测试芯片。每个板包括以预定的试剂分布图案配置的微流体通道。测试芯片包括多个离散测试位置，每个测试位置位于第一预定试剂图案和第二预定试剂图案之间的交点处，其中至少一个所述图案是非线性的。第一通道板允许在所述测试芯片上分配第一试剂，其中所述第一试剂在所述测试位置被固定。第二通道板允许在所述测试芯片上分配第二试剂，其中所述第二试剂包括多个不同的测试样品。

7. 发明申请

WO2004044281A2 NANO-POROUS FIBERS AND PROTEIN MEMBRANES 审中-公开
标题翻译：纳米多孔纤维和蛋白质膜
公开(公告)号：WO2004044281A2
公开(公告)日：2004-05-27
申请号：PCT/US0336307
申请日：2003-11-12
申请人： UNIV CALIFORNIA , HSIEH YOU-LO , XIE JIANGBING , WANG YUHONG , CHEN HONG , LI LEI , ZHANG LIFENG , CECILE CORINE
发明人： HSIEH YOU-LO , XIE JIANGBING , WANG YUHONG , CHEN HONG , LI LEI , ZHANG LIFENG , CECILE CORINE
IPC分类号： D01D5/00 , D01D5/247 , D01F1/10 , D01D
CPC分类号： D01F4/00 , D01D5/0007 , D01D5/0038 , D01D5/247 , D01F1/10 , Y10T428/2907 , Y10T428/2933 , Y10T428/2935 , Y10T442/2525
摘要： The present invention provides nano-porous fibers and protein membrane compositions. In certain embodiments, continuous fiber compositions are provided having nanometer sized diameters and surface pores. In another embodiment, a protein membrane composition is provided comprising a protein; and a polymer, wherein the protein and the polymer are electrospun to form a protein membrane composition. In certain instance, the protein is covalently bound to the fiber.
摘要翻译：本发明提供纳米多孔纤维和蛋白质膜组合物。在某些实施方案中，提供具有纳米尺寸直径和表面孔的连续纤维组合物。在另一个实施方案中，提供了包含蛋白质的蛋白质膜组合物; 和聚合物，其中所述蛋白质和聚合物是静电纺丝以形成蛋白质膜组合物。在某些情况下，蛋白质与纤维共价结合。

8. 发明申请

WO2008076241A1 ENGINEERED COMPOSITE BUILDING MATERIALS AND METHODS OF MAKING SAME 审中-公开
标题翻译：工程复合建筑材料及其制造方法
公开(公告)号：WO2008076241A1
公开(公告)日：2008-06-26
申请号：PCT/US2007025210
申请日：2007-12-10
申请人： JAMES HARDIE INT FINANCE BV , MERKLEY DONALD J , PENG WEILING , CHEN HONG , LUO CAIDIAN
发明人： MERKLEY DONALD J , PENG WEILING , CHEN HONG , LUO CAIDIAN
IPC分类号： E04B1/00 , E04C1/00
CPC分类号： E04C2/26 , C04B20/1029 , C04B28/02 , C04B41/009 , C04B41/483 , C04B41/4884 , C04B41/4922 , C04B41/4961 , C04B41/52 , C04B41/63 , C04B41/64 , C04B41/71 , C04B2111/0062 , C04B2111/27 , C09D1/08 , Y02W30/97 , Y10T428/2495 , Y10T428/249964 , Y10T428/249965 , Y10T428/249968 , Y10T428/259 , C04B20/0048 , C04B24/282 , C04B41/48 , C04B18/24 , C04B16/06 , C04B14/386 , C04B14/48 , C04B14/42
摘要： An engineered composite building material, such as fiber cement, having one or more engineered sub-surface regions designed to provide the building material with improved moisture ingress resistance, paint adhesion, and other mechanical properties is provided. The sub-surface region has a cement-polymer matrix formed by introducing an impregnating agent into the pores of the substrate. The composite building material may be formed by applying impregnating agents to the subsurface regions of the substrate to form chemical and/or mechanical bonds with the matrix of the building material, the reinforcement fibers, and/or the surface coatings applied to the material. The thickness of the sub-surface regions may be controlled by varying the viscosity and porosity of the building material substrate. The cement-polymer building material has enhanced durability, weather resistance, strength, and stiffness.
摘要翻译：提供了一种工程复合建筑材料，例如纤维水泥，其具有设计成为建筑材料提供改进的防水侵蚀性，涂料附着力和其它机械性能的一个或多个工程化的亚表面区域。所述子表面区域具有通过将浸渍剂引入所述基材的孔而形成的水泥 - 聚合物基质。复合建筑材料可以通过将浸渍剂施加到基底的表面下区域来形成，以与施加到材料上的建筑材料，增强纤维和/或表面涂层的基质形成化学和/或机械结合。可以通过改变建筑材料基板的粘度和孔隙率来控制次表面区域的厚度。水泥聚合物建筑材料具有增强的耐久性，耐候性，强度和刚度。

9. 发明申请

WO02088378A2 66784, A NOVEL HUMAN POTASSIUM CHANNEL AND USES THEREFOR 审中-公开
标题翻译： 66784，一个新的人类钾通道及其用途
公开(公告)号：WO02088378A2
公开(公告)日：2002-11-07
申请号：PCT/US0211470
申请日：2002-04-12
申请人： MILLENNIUM PHARM INC , CHEN HONG
发明人： CHEN HONG
IPC分类号： C07K14/705 , C12N15/12 , C12Q
CPC分类号： C07K14/705 , A61K2039/505 , A61K2039/53
摘要： The invention provides isolated nucleic acid molecules, designated 66784 nucleic acid molecules, which encode novel potassium channel family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 66784 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 66784 proteins, fusion proteins, antigenic peptides and anti-66784 antibodies. The present invention also relates to methods for the diagnosis and treatment of metabolic disease, including, but not limited to, obesity, diabetes, anorexia, and cachexia. The present invention describes methods for the diagnostic evaluation and prognosis of various metabolic diseases. The invention also provides methods for identifying a compound capable of modulating metabolic disease. The present invention also provides methods for the identification and therapeutic use of compounds as treatments of metabolic disease.
摘要翻译：本发明提供编码新的钾通道家族成员的分离的核酸分子，命名为66784核酸分子。本发明还提供了反义核酸分子，含有66784个核酸分子的重组表达载体，已经导入了表达载体的宿主细胞，以及其中66784个蛋白质，融合蛋白，抗原肽和抗66784抗体的非人转基因动物。本发明还涉及用于诊断和治疗代谢疾病的方法，包括但不限于肥胖症，糖尿病，厌食症和恶病质。本发明描述了各种代谢疾病的诊断评估和预后的方法。本发明还提供了鉴定能够调节代谢疾病的化合物的方法。本发明还提供了鉴定和治疗化合物作为代谢疾病治疗的方法。

10. 发明申请

WO2009019241A2 BLENDS OF AROMATIC POLYIMIDES AND AROMATIC SULFONE POLYMERS 审中-公开
标题翻译：芳香聚酰亚胺与芳香族磺酸聚合物的共混物
公开(公告)号：WO2009019241A2
公开(公告)日：2009-02-12
申请号：PCT/EP2008060207
申请日：2008-08-04
申请人： SOLVAY ADVANCED POLYMERS LLC , CHEN HONG , UNDERWOOD GEOFFREY , REICHMANN MARK
发明人： CHEN HONG , UNDERWOOD GEOFFREY , REICHMANN MARK
IPC分类号： C08L79/00
CPC分类号： C08G73/1053 , C08J3/005 , C08J2379/08 , C08J2381/06 , C08L79/08 , C08L81/06 , C08L2205/02 , C08L2205/03 , C08L2666/14 , C08L81/00 , C08L2666/20
摘要： Blend (B) comprising : - at least one polyimide (P1), of which more than 50 wt. % of the recurring units (R1) comprise at least one aromatic ring, at least one imide group and 0 to 1 ether group (- O -); - at least one aromatic sulfone polymer (P2); - at least one polyimide (P3), of which more than 50 wt. % of the recurring units (R3) comprise at least one aromatic ring, at least one imide group and at least two ether groups (- O -).
摘要翻译：共混物（B）包含： - 至少一种聚酰亚胺（P1），其中超过50wt。重复单元（R1）的％包含至少一个芳族环，至少一个酰亚胺基和0-1个醚基（-O-）; - 至少一种芳族砜聚合物（P2）; - 至少一种聚酰亚胺（P3），其中超过50wt。重复单元（R3）的％包含至少一个芳环，至少一个酰亚胺基和至少两个醚基（-O-）。

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