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1. 发明申请

WO2010009100A1 CROSS-BAND COMMUNICATIONS IN AN IMPLANTABLE DEVICE 审中-公开
标题翻译：可插入设备中的交叉带通信
公开(公告)号：WO2010009100A1
公开(公告)日：2010-01-21
申请号：PCT/US2009/050505
申请日：2009-07-14
申请人： TRANSOMA MEDICAL, INC. , MOSESOV, Oleg, F. , MILLS, Perry, A.
发明人： MOSESOV, Oleg, F. , MILLS, Perry, A.
IPC分类号： A61B5/00 , A61N1/372
CPC分类号： A61B5/0006 , A61B5/0031 , A61N1/37235 , A61N1/37276 , A61N1/3787 , H04W74/08
摘要： An ambulatory monitoring device includes a sensor to monitor a physiological signal and a battery power source. The device also includes a wireless receiver adapted to monitor a first frequency band having frequencies below 1 MHz and configured to detect and receive, using less than 10 micro-amps of current from the battery power source when operating, wireless communications within the first frequency band from a remote device at least one meter away. The device further includes a wireless transmitter adapted to transmit - after receipt from the remote device of a first wireless communication within the first frequency band that includes an invitation for further communication - a second wireless communication in a second frequency band having frequencies above 10 MHz, the second wireless communication comprising data indicative of the physiological signal as sensed by the sensor.
摘要翻译：移动监视装置包括用于监测生理信号的传感器和电池电源。该设备还包括无线接收器，其适于监测频率低于1MHz的第一频带并被配置为在操作时使用来自电池电源的小于10微安的电流来检测和接收第一频带内的第一频带内的无线通信从远程设备至少一米远。所述设备还包括无线发射器，适于在从所述远程设备接收到包括进一步通信的邀请的所述第一频带内的第一无线通信之后 - 在频率高于10MHz的第二频带中进行第二无线通信，第二无线通信包括指示由传感器感测的生理信号的数据。

2. 发明申请

WO2008070793A3 IMPLANTABLE MONITORING DEVICE ACTIVATOR AND SYSTEM INCLUDING MULTIPLE MODES 审中-公开
公开(公告)号：WO2008070793A3
公开(公告)日：2008-06-12
申请号：PCT/US2007/086678
申请日：2007-12-06
申请人： TRANSOMA MEDICAL, INC. , ARNOLD, John L. , JASPERSON, Keith , KRAMER, Matthew E. , SORENSEN, Claus , STRAWN, Luke , JENSEN, Martin , GRAVERSEN, Bruno
发明人： ARNOLD, John L. , JASPERSON, Keith , KRAMER, Matthew E. , SORENSEN, Claus , STRAWN, Luke , JENSEN, Martin , GRAVERSEN, Bruno
IPC分类号： A61B5/00 , A61B5/0402
摘要： An activator device configured to communicate with an implantable monitoring device includes a first mode and a second mode different from the first mode. The first mode is configured to receive data of asymptomatic events passively recorded by the implantable monitoring device and enable manual signaling of the implantable monitoring device to record data of symptomatic events. The second mode is configured to program electronic settings of the implantable monitoring device.

3. 发明申请

WO2007098228A3 SYSTEM AND METHOD OF MONITORING PHYSIOLOGICAL SIGNALS 审中-公开
标题翻译：监测生理信号的系统和方法
公开(公告)号：WO2007098228A3
公开(公告)日：2008-03-27
申请号：PCT/US2007004556
申请日：2007-02-20
申请人： TRANSOMA MEDICAL INC , BROCKWAY BRIAN P , KOVTUN VLADIMIR , RICCI CARLOS , ARNOLD JOHN , JASPERSON KEITH , SHERWOOD KATHY L , MAZAR SCOTT T
发明人： BROCKWAY BRIAN P , KOVTUN VLADIMIR , RICCI CARLOS , ARNOLD JOHN , JASPERSON KEITH , SHERWOOD KATHY L , MAZAR SCOTT T
IPC分类号： A61B5/0464
CPC分类号： A61B5/046 , A61B5/0006 , A61B5/7275 , A61N1/3702
摘要： A physiological signal monitoring and analysis system including an implantable medical device and a signal processor. The implantable medical device is configured to monitor and record sample segments of at least one physiological signal of a patient at time separated recording intervals over a time period. The signal processor configured to measure values of at least one selected characteristic of the at least one physiological signal from the recorded sample segments, to determine trend information representing a trend in the at least one selected characteristic based on the measured values, and to assess a risk of a physiological event to the patient based on the trend information.
摘要翻译：一种生理信号监测和分析系统，包括可植入医疗装置和信号处理器。可植入医疗装置被配置为在一段时间内以分开的时间间隔监视和记录患者的至少一个生理信号的样本片段。所述信号处理器被配置为测量来自记录的采样段的至少一个生理信号的至少一个所选特征的值，以基于所述测量值确定表示所述至少一个所选特征中的趋势的趋势信息，并且评估根据趋势信息向患者发生生理事件的风险。

4. 发明申请

WO2005110051A2 PORTABLE DEVICE FOR MONITORING ELECTROCARDIOGRAPHIC SIGNALS AND INDICES OF BLOOD FLOW 审中-公开
标题翻译：用于监测电子信号的便携式设备和血液流量指示
公开(公告)号：WO2005110051A2
公开(公告)日：2005-11-24
申请号：PCT/US2005/016396
申请日：2005-05-10
申请人： TRANSOMA MEDICAL, INC. , BENDITT, David, G. , PATTERSON, Robert , LURIE, Keith, G.
发明人： BENDITT, David, G. , PATTERSON, Robert , LURIE, Keith, G.
IPC分类号： A61B5/00 , A61B5/02 , A61B5/0205 , A61B5/021 , A61B5/026 , A61B5/04 , A61B5/0464 , A61B5/05 , A61B5/053
CPC分类号： A61B5/026 , A61B5/0031 , A61B5/02028 , A61B5/02055 , A61B5/021 , A61B5/0295 , A61B5/0464 , A61B5/0535 , A61B5/6837
摘要： Embodiments of the present invention are directed to a physiological monitoring device which is configured to record signals that reflect blood flow and/or blood pressure, and which may also record ECG signals. In one embodiment, a portable monitoring device comprises a plurality of impedance electrodes configured to be coupled to a patient's body and to generate an AC current with an electrical field to detect local electrical impedance of a portion of the patient's body encompassed by the electrical field, the local electrical impedance being a surrogate measure of local blood flow of the portion of the patient's body. At least a portion of the portable monitoring device is configured to be insertable subcutaneously into the patient's body.
摘要翻译：本发明的实施例涉及一种生理监测装置，其被配置为记录反映血流和/或血压的信号，并且还可以记录ECG信号。在一个实施例中，便携式监视设备包括多个阻抗电极，其被配置为耦合到患者的身体并且产生具有电场的AC电流以检测由电场包围的患者身体的一部分的局部电阻抗，局部电阻抗是患者身体部分局部血流量的替代量度。便携式监视装置的至少一部分被配置为可皮下地插入患者体内。

5. 发明申请

WO2008070793A2 IMPLANTABLE MONITORING DEVICE ACTIVATOR AND SYSTEM INCLUDING MULTIPLE MODES 审中-公开
标题翻译：可视化监控设备激活器和系统，其中包括多种模式
公开(公告)号：WO2008070793A2
公开(公告)日：2008-06-12
申请号：PCT/US2007086678
申请日：2007-12-06
申请人： TRANSOMA MEDICAL INC , ARNOLD JOHN L , JASPERSON KEITH , KRAMER MATTHEW E , SORENSEN CLAUS , STRAWN LUKE , JENSEN MARTIN , GRAVERSEN BRUNO
发明人： ARNOLD JOHN L , JASPERSON KEITH , KRAMER MATTHEW E , SORENSEN CLAUS , STRAWN LUKE , JENSEN MARTIN , GRAVERSEN BRUNO
CPC分类号： A61B5/0452 , A61B5/0006 , A61B5/044 , A61N1/08 , A61N1/37235
摘要： An activator device configured to communicate with an implantable monitoring device includes a first mode and a second mode different from the first mode. The first mode is configured to receive data of asymptomatic events passively recorded by the implantable monitoring device and enable manual signaling of the implantable monitoring device to record data of symptomatic events. The second mode is configured to program electronic settings of the implantable monitoring device.
摘要翻译：配置为与可植入监测装置通信的激活装置包括与第一模式不同的第一模式和第二模式。第一模式被配置为接收由可植入监视装置被动地记录的无症状事件的数据，并且使得可植入监视装置的手动信号能够记录症状事件的数据。第二模式被配置为对可植入监视装置的电子设置进行编程。

6. 发明申请

WO2006029186A3 IMPLANTABLE PRESSURE SENSOR WITH PACING CAPABILITY 审中-公开
标题翻译：具有遮盖能力的可植入压力传感器
公开(公告)号：WO2006029186A3
公开(公告)日：2007-02-15
申请号：PCT/US2005031808
申请日：2005-09-08
申请人： TRANSOMA MEDICAL INC , BROCKWAY BRIAN
发明人： BROCKWAY BRIAN
IPC分类号： A61N1/06
CPC分类号： A61N1/3627 , A61N1/0587 , A61N1/36564
摘要： Devices and methods for left ventricular or biventricular pacing plus left ventricular pressure measurement. For example, a pacing lead having a combined electrode and pressure sensor assembly may be used for left ventricular (LV) pacing and pressure measurement. The assembly may include one or more electrodes, a pressure sensor, and a pressure transmission catheter. Such a pacing lead is particularly suitable for biventricular pacing and may be incorporated into a cardiac resynchronization therapy (CRT) system, for example.
摘要翻译：用于左心室或双心室起搏加左心室压力测量的装置和方法。例如，具有组合的电极和压力传感器组件的起搏引线可用于左心室（LV）起搏和压力测量。组件可以包括一个或多个电极，压力传感器和压力传递导管。这样的起搏引线特别适用于双心室起搏，并且可以并入到例如心脏再同步治疗（CRT）系统中。

7. 发明申请

WO2005110051A3 PORTABLE DEVICE FOR MONITORING ELECTROCARDIOGRAPHIC SIGNALS AND INDICES OF BLOOD FLOW 审中-公开
标题翻译：用于监测电子信号的便携式设备和血液流量指示
公开(公告)号：WO2005110051A3
公开(公告)日：2006-08-03
申请号：PCT/US2005016396
申请日：2005-05-10
申请人： TRANSOMA MEDICAL INC , BENDITT DAVID G , PATTERSON ROBERT , LURIE KEITH G
发明人： BENDITT DAVID G , PATTERSON ROBERT , LURIE KEITH G
IPC分类号： A61B5/05 , A61B5/00 , A61B5/02 , A61B5/0205 , A61B5/021 , A61B5/026 , A61B5/04 , A61B5/0464 , A61B5/053 , A61N1/08
CPC分类号： A61B5/026 , A61B5/0031 , A61B5/02028 , A61B5/02055 , A61B5/021 , A61B5/0295 , A61B5/0464 , A61B5/0535 , A61B5/6837
摘要： Embodiments of the present invention are directed to a physiological monitoring device which is configured to record signals that reflect blood flow and/or blood pressure, and which may also record ECG signals. In one embodiment, a portable monitoring device comprises a plurality of impedance electrodes configured to be coupled to a patient's body and to generate an AC current with an electrical field to detect local electrical impedance of a portion of the patient's body encompassed by the electrical field, the local electrical impedance being a surrogate measure of local blood flow of the portion of the patient's body. At least a portion of the portable monitoring device is configured to be insertable subcutaneously into the patient's body.
摘要翻译：本发明的实施例涉及一种生理监测装置，其被配置为记录反映血流和/或血压的信号，并且还可以记录ECG信号。在一个实施例中，便携式监视设备包括多个阻抗电极，其被配置为耦合到患者的身体并且产生具有电场的AC电流以检测由电场包围的患者身体的一部分的局部电阻抗，局部电阻抗是患者身体部分局部血流量的替代量度。便携式监视装置的至少一部分被配置为可皮下地插入患者体内。

8. 发明申请

WO2005051838A3 FEEDBACK CONTROL OF VENTRICULAR ASSIST DEVICES 审中-公开
标题翻译：心室辅助装置的反馈控制
公开(公告)号：WO2005051838A3
公开(公告)日：2006-04-13
申请号：PCT/US2004039274
申请日：2004-11-19
申请人： TRANSOMA MEDICAL INC , BROCKWAY BRIAN P
发明人： BROCKWAY BRIAN P
IPC分类号： A61M1/10 , A61M1/12 , A61N1/362 , B81C20060101
CPC分类号： A61M1/1086 , A61M1/101 , A61M1/122 , A61M1/127 , A61M2205/3334 , A61M2205/8243
摘要： Various devices, systems and methods for providing effective, long term and reliable use of pressure feedback in VADs. Exemplary embodiments are described which provide for direct LV pressure measurement, non-invasive calibration techniques to detect ventricular collapse and recalibrate the feedback mechanism, improved pressure sensor designs with reduced drift, and barometric pressure correction schemes. These devices and methods may be used alone or in combination with each other, and may also be combined with other feedback mechanisms.
摘要翻译：用于在VAD中提供有效，长期和可靠使用压力反馈的各种设备，系统和方法。描述了提供直接LV压力测量，非侵入性校准技术以检测心室塌陷并重新校准反馈机制的示例性实施例，改进的减小漂移的压力传感器设计和大气压力校正方案。这些装置和方法可以单独使用或者彼此组合使用，并且还可以与其他反馈机制组合使用。

9. 发明申请

WO2005086753A2 VASCULAR BLOOD PRESSURE MONITORING SYSTEM WITH TRANSDERMAL CATHETER AND TELEMETRY CAPABILITY 审中-公开
标题翻译：血管导管血管压力监测系统及电导率
公开(公告)号：WO2005086753A2
公开(公告)日：2005-09-22
申请号：PCT/US2005/007312
申请日：2005-03-07
申请人： TRANSOMA MEDICAL, INC. , BROCKWAY, Brian, P. , MILLS, Perry, A.
发明人： BROCKWAY, Brian, P. , MILLS, Perry, A.
IPC分类号： A61B5/00 , A61B5/02 , A61B5/0215
CPC分类号： A61B5/0215 , A61B5/411
摘要： Systems and methods for monitoring intravascular pressure of a patient. The system includes a pressure sensor and catheter assembly having a pressure sensor portion and a transdermal catheter portion. The transdermal catheter portion has a fluid filled lumen and a distal barer to maintain patency. A transmitter unit may be connected to the pressure sensor portion via a lead. The transmitter unit transmits pressure data to a remote receiver unit that may communicate (directly or indirectly) with a cable management device, a data acquisition device, a monitoring instrument, a computer, a modem, a telecommunication line, a network, etc. In addition, the system may include means to correct for pressure variations due to any difference in elevation between the sensor assembly and the heart.
摘要翻译：监测患者血管内压力的系统和方法。该系统包括具有压力传感器部分和透皮导管部分的压力传感器和导管组件。透皮导管部分具有流体填充腔和远端保持器以保持通畅。发射器单元可以经由引线连接到压力传感器部分。发射机单元将压力数据发送到可以与电缆管理设备，数据采集设备，监视仪器，计算机，调制解调器，电信线路，网络等进行通信（直接或间接）的远程接收器单元。此外，系统可以包括用于校正由于传感器组件和心脏之间的任何高度差异而导致的压力变化的装置。

10. 发明申请

WO2009097527A1 MINIMALLY INVASIVE PHYSIOLOGIC PARAMETER RECORDER AND INTRODUCER SYSTEM 审中-公开
标题翻译：微生物生理参数记录仪和引导系统
公开(公告)号：WO2009097527A1
公开(公告)日：2009-08-06
申请号：PCT/US2009/032640
申请日：2009-01-30
申请人： TRANSOMA MEDICAL, INC. , BROCKWAY, Brian P. , MILLS, Perry A.
发明人： BROCKWAY, Brian P. , MILLS, Perry A.
IPC分类号： A61N1/375 , A61B5/00
CPC分类号： A61B5/686 , A61B5/0031 , A61B5/042 , A61B5/0422 , A61B5/076 , A61B5/7232 , A61B2560/0219 , A61B2560/063 , A61B2560/066 , A61B2562/0209 , A61B2562/164 , A61B2562/18 , A61N1/0504 , A61N1/37229 , A61N1/375 , A61N1/3756 , A61N1/3787
摘要： An implantable monitoring device includes a flexible lead body that includes at least one sensing element. The device also includes a rigid main body connected to the flexible lead body at an attachment point. The rigid main body is generally centered about a longitudinal axis defined by the flexible lead body when the lead body is unflexed. The device further includes a measurement circuit, which is housed within the rigid main body and electrically coupled to the at least one sensing element of the flexible lead body and at least another sensing element on an outside surface of the rigid main body. The measurement circuit is configured to measure a potential difference between the at least one sensing element of the flexible lead body and the at least another sensing element of the main body.
摘要翻译：可植入监测装置包括一个包括至少一个传感元件的柔性引线体。该装置还包括在附接点处连接到柔性引线主体的刚性主体。当铅体未折叠时，刚性主体通常由柔性引线体限定的纵向轴线对准。该装置还包括测量电路，其被容纳在刚性主体内并电耦合到柔性引线本体的至少一个感测元件和至少另一感测元件在刚性主体的外表面上。测量电路被配置为测量柔性引线体的至少一个感测元件与主体的至少另一感测元件之间的电位差。

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