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    • 7. 发明申请
    • SILICON COMPOUNDS WITH MICROBIOCIDAL ACTIVITY
    • 具有微生物活性的硅化合物
    • WO2005028485A1
    • 2005-03-31
    • PCT/EP2004/010009
    • 2004-09-08
    • SYNGENTA PARTICIPATIONS AGEHRENFREUND, JosefLAMBERTH, ClemensTOBLER, HansWALTHER, Harald
    • EHRENFREUND, JosefLAMBERTH, ClemensTOBLER, HansWALTHER, Harald
    • C07F7/08
    • C07F7/0812A01N55/00
    • Fungicidal compounds of formula (I): where X is O or S; RING is phenyl or thienyl; Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, the ring being substituted by one to four groups R 4 ; R 1 is hydrogen, optionally substituted (C 1-4 )alkyl, formyl, optionally substituted (C 1-4 )alkylC(=O), optionally substituted (C 1-4 )alkylC(=O)O, optionally substituted (C 1-4 )alkoxy(C 1-4 )alkyl, optionally substituted allyl, optionally substituted propargyl or optionally substituted allenyl; each R 2 is, independently, halogen, optionally substituted (C 1-4 )alkyl, optionally substituted (C 1-4 )alkoxy or optionally substituted (C 1-4 )alkoxy(C 1-4 )alkyl; R 3 is (CR a R b ) m _ Cy-(CR C R d ) n -Y; each R 4 is, independently, selected from halogen, C 1-3 alkyl, C 1-3 haloalkyl, C 1-3 alkoxy(C 1-3 )alkyl and cyano; R a , R b , R c and R d are each, independently, hydrogen or optionally substituted (C 1-4 )alkyl; Cy is an optionally substituted carbocyclic or heterocyclic 3-7 membered ring which may be saturated, unsaturated or aromatic and which optionally contains a silicon atom as a ring member; (CR a R b ) m and (CR c R d ) n may be bound either to the same carbon or silicon atom of Cy or to different atoms separated by 1, 2 or 3 ring members; Y is Si(O p Z 1 )(O q Z 2 )(O s Z) and provided that Cy contains a silicon atom as a ring member then Y may also be hydrogen; Z is C 1-4 alkyl or C 2-4 alkenyl (each of which is optionally interrupted by one heteroatom selected from O, S and N and is optionally substituted by one to three independently selected halogen atoms); Z 1 and Z 2 are, independently, methyl or ethyl; in and n are each, independently, 0, 1, 2 or 3; p, q and s are each, independently, 0 or 1; and r is 0, 1 or 2; or an N-oxide thereof; novel intermediates used in the preparation of these compounds, agrochemical compositions which comprise at least one of the novel compounds as active ingredient and the use of the active ingredients or compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.
    • 式(I)的杀真菌化合物:其中X为O或S; RING是苯基或噻吩基; Het是含有一至三个杂原子的5-或6-元杂环,各自独立地选自氧,氮和硫,该环被一至四个R 4基团取代; 任选取代的(C 1-4)烷基C(= O),任选取代的(C 1-4)烷基C(= O)O,任选取代的(C 1 -C 6)烷基, 4)烷氧基(C 1-4)烷基,任选取代的烯丙基,任选取代的炔丙基或任选取代的烯丙基; 每个R 2独立地是卤素,任选取代的(C 1-4)烷基,任选取代的(C 1-4)烷氧基或任选取代的(C 1-4)烷氧基(C 1-4)烷基; R 3是(CR a R b)m - Cy-(CR C R d)n-Y; 每个R 4独立地选自卤素,C 1-3烷基,C 1-3卤代烷基,C 1-3烷氧基(C 1-3)烷基和氰基; R a,R b,R c和R d各自独立地为氢或任选取代的(C 1-4)烷基; Cy是任选取代的碳环或杂环3-7元环,其可以是饱和的,不饱和的或芳族的,并且任选地含有硅原子作为环成员; (CR a R b)m和(CR c R d)n可以结合于Cy的相同碳原子或硅原子或与1,2或3个环成员分隔的不同原子; Y是Si(OpZ 1)(Oq Z 2)(OsZ),并且假设Cy含有硅原子作为环成员,则Y也可以是氢; Z是C 1-4烷基或C 2-4链烯基(其各自任选地被选自O,S和N的一个杂原子中断,并且任选被一至三个独立选择的卤素原子取代); Z 1和Z 2独立地是甲基或乙基; in和n各自独立地为0,1,2或3; p,q和s各自独立地为0或1; 和r为0,1或2; 或其N-氧化物; 用于制备这些化合物的新型中间体,包含至少一种新化合物作为活性成分的农用化学组合物以及在农业或园艺中使用活性成分或组合物来控制或预防植物病原微生物侵染植物,优选真菌 。
    • 8. 发明申请
    • BIPHENYL DERIVATIVES AND THEIR USE AS FUNGICIDES
    • 苯乙烯衍生物及其作为杀真菌剂使用
    • WO2004058723A1
    • 2004-07-15
    • PCT/EP2003/014248
    • 2003-12-15
    • SYNGENTA PARTICIPATIONS AGEHRENFREUND, JosefLAMBERTH, ClemensTOBLER, HansWALTER, Harald
    • EHRENFREUND, JosefLAMBERTH, ClemensTOBLER, HansWALTER, Harald
    • C07D231/14
    • C07D213/82A01N43/06A01N43/14A01N43/32A01N43/36A01N43/40A01N43/54A01N43/56A01N43/58A01N43/60A01N43/74A01N43/80C07C25/24C07C211/45C07C211/52C07C217/76C07C219/32C07C233/03C07C2601/02C07C2601/08C07D207/34C07D231/14C07D231/16C07D237/24C07D239/28C07D239/30C07D263/34C07D277/56C07D307/68C07D309/28C07D327/06C07D333/38C07F7/0812
    • A fungicidally active compound of formula (I): where Het is a substituted 5- or 6-membered heterocyclic ring; R 1 is hydrogen, formyl, CO-C 1-4 alkyl, COO-C 1-4 alkyl, C 1-4 alkoxy(C 1-4 )alkylene, CO-C 1-4 alkylenoxy(C 1-4 )alkyl, propargyl or allenyl; R 2 , R 3 , R 4 and R 5 are each, independently, hydrogen, halogen, methyl or CF 3 ; each R 6 is, independently, halogen, methyl or CF 3 ; R 7 is (Z) m C=C(Y 1 ), (Z) m C(Y 1 )=C(Y 2 )(Y 3 ) or tri(C 1-4 )alkylsilyl; X is O or S; Y 1 , Y 2 and Y 3 are each, independently, hydrogen, halogen, C 1-6 alkyl [optionally substituted by one or more substituents each independently selected from halogen, hydroxy, C 1-4 alkoxy, C 1-4 haloalkoxy, C 1-4 alkylthio, C 1-4 haloalkylthio, C 1-4 alkylamino, di(C 1-4 )alkylamino, C 1-4 alkoxycarbonyl, C 1-4 alkylcarbonyloxy and tri(C 1-4 )alkylsilyl], C 2-4 alkenyl [optionally substituted by one or more substituents each independently selected from halogen], C 2-4 alkynyl [optionally substituted by one or more substituents each independently selected from halogen], C 3-7 cycloalkyl [optionally substituted by one or more substituents each independently selected from halogen, C 1-4 alkyl and C 1-4 haloalkyl] or tri(C 1­4 )alkylsilyl; Z is C 1-4 alkylene [optionally substituted by one or more substituents each independently selected from hydroxy, cyano, C 1-4 alkoxy, halogen, C 1-4 haloalkyl, C 1-4 haloalkoxy, C 1-4 alkylthio, COOH and COO-C 1-4 alkyl]; m is 0 or 1; and n is 0, 1 or 2; the invention also relates to novel intermediates used in the preparation of these compounds, to agrochemical compositions which comprise at least one of the novel compounds as active ingredient and to the use of the active ingredients or compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.
    • 杀真菌活性的式(I)化合物:其中Het是取代的5或6元杂环; R 1是氢,甲酰基,CO-C 1-4烷基,COO-C 1-4烷基,C 1-4烷氧基(C 1-4)亚烷基,CO-C 1-4亚烷基氧基(C 1-4)烷基,炔丙基或烯丙基 ; R 2,R 3,R 4和R 5各自独立地为氢,卤素,甲基或CF 3; 每个R 6独立地是卤素,甲基或CF 3; R 7是(Z)m C = C(Y 1),(Z)m C(Y 1)= C(Y 2)(Y 3)或三(C 1-4)烷基甲硅烷基 ; X为O或S; Y 1,Y 2和Y 3各自独立地为氢,卤素,C 1-6烷基(任选被一个或多个取代基取代,各自独立地选自卤素,羟基,C 1-4烷氧基, 4卤代烷氧基,C 1-4烷硫基,C 1-4卤代烷硫基,C 1-4烷基氨基,二(C 1-4)烷基氨基,C 1-4烷氧基羰基,C 1-4烷基羰基氧基和三(C 1-4)烷基甲硅烷基],C 2-4链烯基[ 任选被一个或多个各自独立地选自卤素的取代基取代的C 2-4炔基[任选被一个或多个各自独立地选自卤素的取代基取代],C 3-7环烷基[任选地被一个或多个各自独立地选自卤素 ,C 1-4烷基和C 1-4卤代烷基]或三(C 14)烷基甲硅烷基; Z是C1-4亚烷基[任选地被一个或多个取代基取代,各自独立地选自羟基,氰基,C 1-4烷氧基,卤素,C 1-4卤代烷基,C 1-4卤代烷氧基,C 1-4烷硫基,COOH和COO- 4烷基]; m为0或1; 并且n为0,1或2; 本发明还涉及用于制备这些化合物的新型中间体,包含至少一种新化合物作为活性成分的农用化学组合物以及农业或园艺中的活性成分或组合物用于控制或预防 植物通过植物病原微生物,优选真菌。
    • 10. 发明申请
    • TRIAZOLOPYRIMIDINESULFONAMIDES AS HERBICIDES
    • 三唑并嘧啶二酮作为除草剂
    • WO1993016079A1
    • 1993-08-19
    • PCT/EP1993000171
    • 1993-01-26
    • CIBA-GEIGY AGTOBLER, Hans
    • CIBA-GEIGY AG
    • C07D487/04
    • C07D487/04A01N43/90C07D305/08
    • Triazolo[1,5-a]pyrimidine-2-sulfonamides of formula (I), in which R1 and R2 independently of one another are hydrogen, halogen, C1-C4alkyl, C1-C4haloalkyl, C1-C4alkoxy, C1-C4haloalkoxy, C1-C4alkoxy-C1-C4-alkyl, nitro, phenyl or S(O)nR3; R3 is C1-C4alkyl, C1-C4haloalkyl, C2-C4alkenyl, C2-C4alkynyl, benzyl or optionally substituted phenyl; n is the number 0, 1 or 2; R4, R5, R6, R7 and R8 independently of one another are hydrogen or C1-C4alkyl; and X and Y independently of one another are hydrogen, C1-C4alkyl or C3-C6cycloalkyl; and the agrochemically acceptable salts of these compounds, with the proviso that the radicals X and Y are not simultaneously hydrogen, have herbicidal properties pre- and post-emergence and are readily degradable. Described are the preparation of these compounds and their use as herbicidal active ingredients.
    • 式(I)的三唑并[1,5-a]嘧啶-2-磺酰胺,其中R 1和R 2彼此独立地是氢,卤素,C 1 -C 4烷基,C 1 -C 4卤代烷基,C 1 -C 4烷氧基,C 1 -C 4卤代烷氧基,C 1 -C 1-4烷氧基-C 1 -C 4 - 烷基,硝基,苯基或S(O)n R 3; R 3是C 1 -C 4烷基,C 1 -C 4卤代烷基,C 2 -C 4烯基,C 2 -C 4炔基,苄基或任选取代的苯基; n是数字0,1或2; R 4,R 5,R 6,R 7和R 8彼此独立地是氢或C 1 -C 4烷基; X和Y彼此独立地是氢,C 1 -C 4烷基或C 3 -C 6环烷基; 和这些化合物的农业化学可接受的盐,条件是基团X和Y不同时为氢,在芽前和出苗后具有除草性,并且易于降解。 描述了这些化合物的制备及其作为除草活性成分的用途。