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    • 3. 发明申请
    • USE OF THE PREGNANE GLYCOSIDES IN THE TREATMENT/MANAGEMENT OF OBESITY, OBESITY-RELATED AND OTHER DISORDERS
    • 在治疗或治疗肥胖,与肥胖相关的疾病和其他疾病中使用孕激素治疗糖尿病
    • WO2005102371A3
    • 2006-01-26
    • PCT/IN2005000131
    • 2005-04-27
    • RAJENDRAN RAMASWAMYRAJENDRAN KAMALA
    • RAJENDRAN RAMASWAMYRAJENDRAN KAMALA
    • A61K36/185A61K36/27A61K36/328A61K36/38A61K36/42A61K36/48A61K36/484A61K36/54A61K36/82A61K36/899A61K35/78
    • A61K36/82A61K36/185A61K36/27A61K36/328A61K36/38A61K36/42A61K36/48A61K36/484A61K36/54A61K36/752A61K36/899A61K2300/00
    • Doses containing pregnane glycosides alone, and in combination with several other compounds for treatment of disorders/conditions such as obesity, low BMR, hyperglycaemia, hypertension, hypercholesterolemia, Type (2) diabetes, migraine, osteo-arthritis and joint degradation/inflammation, clinical depression, menopausal syndrome, ageing syndrome, circulation syndrome, capillary degeneration, reduced cognitive and memory function, hearing loss, sexual dysfunction and others are disclosed. Doses are also provided for the regulation/improvement of various physiological parameters/conditions/functions associated with said disorders and others such as skin condition, joint mobility, mood, memory function and recall, lean body mass, stamina, libido and others. The preferred glycoside is a caralluma plant extract containing a synergical mixture of the pregnane glycosides, caratubersides and boucerosides containing 90-95% of the former. Combinations thereof with the extracts of Green tea, Fenugreek, Ashwagandha, Shilajith, Commiphora Mukul, Garcinia, Hibiscus Subdarifa, Coccinia, Bittergourd, Cinnamon, Liquorice, Red clover, Hops flowers, Pomegranate and with Glucosamine, Zinc monomethionine, Citrus bioflavonoids, Rutin, Bamboo silica, Shilajith, Saponin glycosides and the biders of caralluma, and selenium are disclosed.
    • 单独含有孕烷糖苷的剂量,以及与其他几种化合物组合用于治疗疾病/病症如肥胖,低BMR,高血糖,高血压,高胆固醇血症,类型(2)糖尿病,偏头痛,骨关节炎和关节降解/炎症的临床 抑郁症,绝经综合征,衰老综合征,循环综合征,毛细血管变性,认知和记忆功能减退,听力丧失,性功能障碍等。 还提供了用于调节/改善与所述障碍和其它诸如皮肤状况,关节活动性,情绪,记忆功能和召回,瘦体重,耐力,性欲等的各种生理参数/状况/功能的剂量。 优选的糖苷是含有含有90-95%前者的孕烷糖苷,辅助加速剂和boucerosides的协同混合物的卡拉酵母植物提取物。 与绿茶,葫芦巴,Ashwagandha,Shilajith,Commiphora Mukul,Garcinia,Hibiscus Subdarifa,Coccinia,Bittergourd,Cinnamon,Liquorice,红三叶草,Hops花,石榴和葡萄糖胺,单甲硫氨酸,柑橘类生物类黄酮,芦丁, 披露了竹二氧化硅,Shilajith,皂苷和卡拉卢的硒,硒。
    • 7. 发明申请
    • EXTRACTION OF PHYTOCHEMICALS FROM PLANT MATTER
    • 从植物提取物理化学品
    • WO2013183065A3
    • 2015-07-09
    • PCT/IN2013000351
    • 2013-06-03
    • RAJENDRAN RAMASWAMYRAJENDRAN KAMALA
    • RAJENDRAN RAMASWAMYRAJENDRAN KAMALA
    • B01D11/00B01D11/02
    • A61K36/185A61K36/24A61K36/47A61K36/61A61K36/752A61K36/82A61K2236/39A61K2300/00
    • In a method/process for the extraction of a first plant matter(s) with an alcoholic solvent, the former is treated with a second plant matter(s) containing acidic components) that converts) one or more of the insoluble constituents thereof into soluble forms, thus enabling the extraction of a wider range of constituents. Plant species having the desired nutrients and the appropriate acidic components are reacted and extracted to give a composition containing the desired vitamins and minerals(and/or other nutrients), in substantially the desired proportions through a single extraction operation with a single solvent thus eliminating several processing steps involved in conventional processes. Suitable acidic plant matters are amla fruits, lemon peels etc. Preferred solvent is aqueous ethanol. Said acidic treatment may be carried out before or during the extraction operation. Conversion into forms having enhanced solubility and/or increased biological and metabolical activity/efficacy is also feasible.
    • 在用醇溶剂萃取第一植物物质的方法/方法中,前者用含有酸性成分的第二植物物质处理),其将一种或多种不溶性成分转化成可溶的 形式,从而能够提取更广泛的成分。 具有所需营养物质和合适的酸性成分的植物物种被反应并提取,以通过单一溶剂的单次提取操作,以基本上所需的比例提供含有所需维生素和矿物质(和/或其他营养物质)的组合物,从而消除了几种 常规工艺中涉及的加工步骤。 合适的酸性植物物质是水果,柠檬皮等。优选的溶剂是乙醇水溶液。 所述酸性处理可以在提取操作之前或期间进行。 转化成具有增强的溶解度和/或增加的生物学和代谢活性/功效的形式也是可行的。
    • 8. 发明申请
    • EXTRACTION OF PHYTOCHEMICALS FROM TRICHILIA CONNAROIDES
    • 从TRICHILIA连接物提取生物化学品
    • WO2013183064A3
    • 2015-07-09
    • PCT/IN2013000350
    • 2013-06-03
    • RAJENDRAN RAMASWAMYRAJENDRAN KAMALA
    • RAJENDRAN RAMASWAMYRAJENDRAN KAMALAPURNIMA ASHOK
    • B01D11/00
    • A61K36/185A23L33/105A61K2236/39
    • In the extraction of TC(Trichilia connaroides) by solvent(s), the former is reacted with acidic plant matter such as, for example, amla fruit matter(Emblica officinalis) which converts some of the insoluble principles therein into soluble forms, thus enhancing the extraction range and yield. In extraction by water, the adoption of amla fruit matter increases the TC principles yield from about 10% to about 12% by wt., of the saponins from about 8.2% to about 12.3% by wt. and of the terpenes from about 1.1% to about 3.9% by wt. The corresponding yield figures in extraction by aq. ethanol, respectively with and without the adoption of amla fruit matter are 14%, 15.6% and 5.5% by wt. and 8%, 11.1% and 4.1% by wt. for the three sets of compounds respectively. With both solvents, the adoption of amla increases the yields, said increases being greater in the case of aq. ethanol.
    • 在通过溶剂提取TC(Trichilia connaroides)时,前者与酸性植物物质例如Amla果实物质(Emblica officinalis)反应,将其中的一些不溶性原理转化为可溶形式,从而增强 提取范围和产量。 在用水提取时,采用amla果实物质将TC原料产率从约10重量%至约12重量%的皂苷从约8.2重量%增加至约12.3重量%。 和约1.1%至约3.9%的萜烯。 相应的产量数字提取方法。 乙醇,分别有和没有采用amla果实物质分别为14%,15.6%和5.5%。 和8%,11.1%和4.1%。 分别为三组化合物。 使用这两种溶剂,采用amla可以提高产量,表示在aq情况下增加更大。 乙醇。
    • 9. 发明申请
    • EXTRACTION OF PHYTOCHEMICALS FROM PLANT MATTER
    • 从植物提取物理化学品
    • WO2013183065A2
    • 2013-12-12
    • PCT/IN2013/000351
    • 2013-06-03
    • RAJENDRAN, RamaswamyRAJENDRAN, Kamala
    • RAJENDRAN, RamaswamyRAJENDRAN, Kamala
    • A61K36/185
    • A61K36/185A61K36/24A61K36/47A61K36/61A61K36/752A61K36/82A61K2236/39A61K2300/00
    • In a method/process for the extraction of a first plant matter(s) with an alcoholic solvent, the former is treated with a second plant matter(s) containing acidic components) that converts) one or more of the insoluble constituents thereof into soluble forms, thus enabling the extraction of a wider range of constituents. Plant species having the desired nutrients and the appropriate acidic components are reacted and extracted to give a composition containing the desired vitamins and minerals(and/or other nutrients), in substantially the desired proportions through a single extraction operation with a single solvent thus eliminating several processing steps involved in conventional processes. Suitable acidic plant matters are amla fruits, lemon peels etc. Preferred solvent is aqueous ethanol. Said acidic treatment may be carried out before or during the extraction operation. Conversion into forms having enhanced solubility and/or increased biological and metabolical activity/efficacy is also feasible.
    • 在用醇溶剂萃取第一植物物质的方法/方法中,前者用含有酸性成分的第二植物物质处理),其将一种或多种不溶性成分转化成可溶的 形式,从而能够提取更广泛的成分。 具有所需营养物质和合适的酸性成分的植物物种被反应并提取,以通过单一溶剂的单次提取操作,以基本上所需的比例提供含有所需维生素和矿物质(和/或其他营养物质)的组合物,从而消除了几种 常规工艺中涉及的加工步骤。 合适的酸性植物物质是水果,柠檬皮等。优选的溶剂是乙醇水溶液。 所述酸性处理可以在提取操作之前或期间进行。 转化成具有增强的溶解度和/或增加的生物学和代谢活性/功效的形式也是可行的。
    • 10. 发明申请
    • EXTRACTION OF B-VITAMINS FROM PLANT MATTER
    • 从植物提取B维生素
    • WO2013018103A2
    • 2013-02-07
    • PCT/IN2012/000528
    • 2012-07-30
    • RAJENDRAN, RamaswamyRAJENDRAN, Kamala
    • RAJENDRAN, RamaswamyRAJENDRAN, Kamala
    • C07D475/06
    • A61K36/752A61K31/16A61K31/4406A61K31/4415A61K31/51A61K31/519A61K31/525A61K36/53A61K36/61C07D415/00C07D475/06C07D475/14C07H1/08C07H23/00
    • A process for the extraction of the B group of vitamins from a first plant matter is disclosed wherein, prior to the said extraction operation, the first plant matter is treated with a second plant matter comprising acidic compounds. The acidification converts the said vitamins into more water-soluble forms and increases the yield thereof. In one example, the first plant matter comprises guava fruit matter, holy basil leaves and lemon peels, the two last-mentioned plant species being the source of the acidic compounds. The vitamins extracted and the proportions thereof can be controlled by a suitable choice of the plant species constituting the first and second plant matters and their quantities such as to give a substantially ready formulation conforming to RDA values or other requirements. The vitamins extracted are Bl, B2, B3, B5, B6 and B9, the above combination of plant matters giving higher yield than others. The process is of general applicability to other plant constituents.
    • 公开了从第一植物物质中提取B族维生素的方法,其中在所述提取操作之前,用包含酸性化合物的第二植物物质处理第一植物物质。 酸化将所述维生素转化为更多的水溶性形式并提高其产率。 在一个实例中,第一植物物质包括番石榴果实物质,圣罗勒叶和柠檬皮,两种最后提到的植物物种是酸性化合物的来源。 提取的维生素及其比例可以通过适当选择构成第一和第二植物物质的植物物种及其数量来控制,从而给出符合RDA值或其他要求的基本准备的制剂。 提取的维生素是B1,B2,B3,B5,B6和B9,上述植物物质的组合比其他物质产生更高的产量。 该方法对其他植物成分具有普遍适用性。