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1. 发明申请

WO2012018577A1 FREQUENCY DOUBLED LASER WITH FOLDED OPTICAL PATH 审中-公开
标题翻译：带折叠光路的频率双倍激光
公开(公告)号：WO2012018577A1
公开(公告)日：2012-02-09
申请号：PCT/US2011/045156
申请日：2011-07-25
申请人： CORNING INCORPORATED , GOLLIER, Jacques , PIECH, Garrett A. , STALOFF, Daniel Max
发明人： GOLLIER, Jacques , PIECH, Garrett A. , STALOFF, Daniel Max
IPC分类号： H01S5/022 , H01S5/00 , G02B6/42 , G02B26/08 , G02B3/02 , G02F1/377
CPC分类号： H01S5/0092 , H01S5/0014 , H01S5/0071 , H01S5/02248
摘要： A folded laser system comprising: a coherent light source (20); a reflector (50); a lens I component (30) situated between the light source and the reflector; and a non-linear optical crystal (70), wherein the light source and the non-linear optical crystal are separated by a distance d>50 μm The lens component is positioned to provide a collimated beam when intercepting light from the light source, such that the collimated beam is at an angle to the optical axis of the lens, the reflector is situated to intercept the collimated beam and to reflect the collimated beam to the non-linear optical crystal through the lens; and the lens component is structured to provide an image on the non-linear optical crystal.
摘要翻译：一种折叠激光系统，包括：相干光源（20）; 反射器（50）; 位于光源和反射器之间的透镜I部件（30）和非线性光学晶体（70），其中所述光源和所述非线性光学晶体被隔开距离d>50μm。所述透镜部件定位成在截取来自所述光源的光时提供准直光束，准直光束与透镜的光轴成一定角度，反射器被定位成拦截准直光束并通过透镜将准直光束反射到非线性光学晶体; 并且透镜部件被构造成在非线性光学晶体上提供图像。

2. 发明申请

WO2011156214A1 METHODS AND SYSTEMS FOR OPTIMIZING THE ALIGNMENT OF OPTICAL PACKAGES 审中-公开
标题翻译：优化光学配件对准的方法和系统
公开(公告)号：WO2011156214A1
公开(公告)日：2011-12-15
申请号：PCT/US2011/039006
申请日：2011-06-03
申请人： CORNING INCORPORATED , GOLLIER, Jacques , PIECH, Garrett A. , RICKETTS, Daniel O.
发明人： GOLLIER, Jacques , PIECH, Garrett A. , RICKETTS, Daniel O.
IPC分类号： G02B26/10 , G02F1/377
CPC分类号： G02B26/101 , G02F1/377
摘要： A method for optimizing the alignment of an optical package includes directing a beam spot of a laser along a folded optical path and onto a waveguide portion of a wavelength conversion. The output intensity of the wavelength conversion device is measured as a position of an adjustable optical component is adjusted about a first scanning axis and a second scanning axis thereby traversing the beam spot along a first and second scan lines on the waveguide portion of the wavelength conversion device. The change in the output intensity of the wavelength conversion device is then determined based on the adjusted position of the adjustable optical component. The adjustable optical component is then positioned on the first scanning axis and the second scanning axis based on the determined changes in the output intensity of the wavelength conversion device such that the output intensity of the wavelength conversion device is maximized.
摘要翻译：用于优化光学封装的对准的方法包括将激光束的束斑沿着折叠的光路引导到波长转换的波导部分上。测量波长转换装置的输出强度，因为可调节光学部件的位置围绕第一扫描轴和第二扫描轴进行调节，从而沿着波长转换的波导部分上的第一和第二扫描线遍及光束点设备。然后，基于可调节光学部件的调整位置来确定波长转换装置的输出强度的变化。基于所确定的波长转换装置的输出强度的变化，使可调光学部件位于第一扫描轴和第二扫描轴上，使得波长转换装置的输出强度最大化。

3. 发明申请

WO2010075017A3 MULTI-VARIABLE CONTROL METHODS FOR OPTICAL PACKAGES 审中-公开
标题翻译：用于光学包装的多变量控制方法
公开(公告)号：WO2010075017A3
公开(公告)日：2011-03-10
申请号：PCT/US2009067818
申请日：2009-12-14
申请人： CORNING INC , GOLLIER JACQUES , PIECH GARRETT A , PIKULA DRAGAN , RICKETTS DANIEL O
发明人： GOLLIER JACQUES , PIECH GARRETT A , PIKULA DRAGAN , RICKETTS DANIEL O
IPC分类号： H01S5/0683 , H01S5/022 , H01S5/0687
CPC分类号： H01S5/0683 , G02F1/35 , G02F1/3775 , H01S5/0092 , H01S5/06256 , H01S5/0687
摘要： According to one embodiment of the present invention, an optical package comprises one or more semiconductor lasers coupled to a wavelength conversion device with adaptive optics. The optical package also comprises a package controller programmed to operate the semiconductor laser and the adaptive optics based on modulated feedback control signals supplied to the wavelength selective section of the semiconductor laser and the adaptive optics. The wavelength control signal supplied to the wavelength selective section of the semiconductor laser may be adjusted based on the modulated wavelength feedback control signal such that the response parameter of the wavelength conversion device is optimized. Similarly, the position control signals supplied to the adaptive optics may be adjusted based on the modulated feedback position control signals such that the response parameter of the wavelength conversion device is optimized.
摘要翻译：根据本发明的一个实施例，光学封装包括耦合到具有自适应光学器件的波长转换器件的一个或多个半导体激光器。光学封装还包括编程为基于提供给半导体激光器和自适应光学器件的波长选择部分的调制反馈控制信号来操作半导体激光器和自适应光学器件的封装控制器。提供给半导体激光器的波长选择部分的波长控制信号可以基于调制的波长反馈控制信号进行调整，使得波长转换器件的响应参数被优化。类似地，可以基于调制的反馈位置控制信号来调整提供给自适应光学器件的位置控制信号，使得波长转换装置的响应参数被优化。

4. 发明申请

WO2011017147A1 LABEL-INDEPENDENT OPTICAL READER SYSTEM AND METHODS WITH OPTICAL SCANNING 审中-公开
标题翻译：标签相关光学读取器系统和光学扫描方法
公开(公告)号：WO2011017147A1
公开(公告)日：2011-02-10
申请号：PCT/US2010/043486
申请日：2010-07-28
申请人： CORNING INCORPORATED , GOLLIER, Jacques , PIECH, Garrett A , WEBB, Michael B
发明人： GOLLIER, Jacques , PIECH, Garrett A , WEBB, Michael B
IPC分类号： G01N21/77
CPC分类号： G01N21/7743 , G02B26/0833 , G02B26/101
摘要： Optical reader systems and methods for label-independent reading of resonant waveguide (RWG) biosensors operably supported by a microplate as defined herein. The system includes a light source, a spectrometer unit, a beam-forming optical system and a scanning optical system that includes a scanning mirror device, a mirror device driver operably coupled to the scanning mirror device, and an F-theta lens arranged between the microplate and the beam-forming optical system. Some systems use multiple optical beams to scan multiple biosensors at once without having to move the microplate. Asynchronous scanning of multiple beams allows for reducing the number of spectrometer units needed.
摘要翻译：光学读取器系统和用于标签无关读取谐振波导（RWG）生物传感器的方法，其可操作地由如本文定义的微孔板支撑。该系统包括光源，光谱仪单元，波束形成光学系统和扫描光学系统，其包括扫描镜装置，可操作地耦合到扫描反射镜装置的镜装置驱动器和布置在扫描镜装置之间的F-theta透镜微板和波束形成光学系统。一些系统使用多个光束一次扫描多个生物传感器，而不必移动微孔板。多个波束的异步扫描允许减少所需的光谱仪单元的数量。

5. 发明申请

WO2009134407A1 OPTICAL PACKAGE HAVING DEFORMABLE MIRRORS FOR FOCUS COMPENSATION 审中-公开
标题翻译：具有可变形镜的光学包装用于聚焦补偿
公开(公告)号：WO2009134407A1
公开(公告)日：2009-11-05
申请号：PCT/US2009/002662
申请日：2009-04-30
申请人： CORNING INCORPORATED , GOLLIER, Jacques , PIECH, Garrett, A
发明人： GOLLIER, Jacques , PIECH, Garrett, A
IPC分类号： G02B26/12
CPC分类号： G02B26/0825 , G02B26/0833 , G02F1/377 , G02F2001/3503
摘要： An optical package includes a semiconductor laser, an adjustable mirror and a wavelength conversion device comprising a waveguide portion. The semiconductor laser, adjustable mirror, and wavelength conversion device are oriented to form an optical pathway between an output of the semiconductor laser and an input of the wavelength conversion device. The beam of the semiconductor laser is directed along the optical pathway and onto the adjustable mirror where the beam is reflected by the adjustable mirror onto the waveguide portion of the wavelength conversion device. The adjustable mirror may also be either thermally or mechanically deformable such that, when the adjustable mirror is deformed, the path of the beam along the optical pathway is altered thereby focusing the beam on the waveguide portion of the wavelength conversion device. The adjustable mirror may be adjusted such that the beam of the semiconductor laser is positioned on the waveguide portion of the wavelength conversion device.
摘要翻译：光学封装包括半导体激光器，可调镜和包括波导部分的波长转换器件。半导体激光器，可调镜和波长转换器件被定向成在半导体激光器的输出端与波长转换器件的输入端之间形成光路。半导体激光束的光束沿着光学路径被引导到可调整反射镜上，其中光束被可调节反射镜反射到波长转换器件的波导部分上。可调节反射镜也可以是热或机械可变形的，使得当可调节反射镜变形时，沿着光学路径的光束的路径被改变，从而将光束聚焦在波长转换装置的波导部分上。可调节可调镜，使得半导体激光束的光束位于波长转换装置的波导部分上。

6. 发明申请

WO2008033311A1 OPTICAL INTERROGATION SYSTEM AND MICROPLATE POSITION CORRECTION METHOD 审中-公开
标题翻译：光学系统与微波位置校正方法
公开(公告)号：WO2008033311A1
公开(公告)日：2008-03-20
申请号：PCT/US2007/019680
申请日：2007-09-11
申请人： CORNING INCORPORATED , DAILEY, Michael, J, Jr. , PIECH, Garrett A , SHEDD, Gordon M , WEBB, Michael B , ZAMBRANO, Elvis A
发明人： DAILEY, Michael, J, Jr. , PIECH, Garrett A , SHEDD, Gordon M , WEBB, Michael B , ZAMBRANO, Elvis A
IPC分类号： G01N21/25 , G01N21/64
CPC分类号： G01N21/253 , B01L3/5085 , B01L9/50 , B01L2300/0636 , G01N35/028
摘要： An optical interrogation system and method are described herein that are capable of detecting and correcting a positional misalignment of a label independent detection (LID) microplate so that the LID microplate can be properly interrogated after being removed from and then re-inserted back into a microplate holder/XY translation stage.
摘要翻译：本文描述了能够检测和校正标签无关检测（LID）微孔板的位置不对准的光学询问系统和方法，使得LID微孔板在被移除之后被重新插入微孔板之后被适当询问持有人/ XY翻译阶段。

7. 发明申请

WO2007106306A3 REFERENCE MICROPLATES AND METHODS FOR MAKING AND USING THE REFERENCE MICROPLATES 审中-公开
公开(公告)号：WO2007106306A3
公开(公告)日：2007-09-20
申请号：PCT/US2007/004537
申请日：2007-02-20
申请人： CORNING INCORPORATED , PASTEL, David, A. , PIECH, Garrett, A. , SHEDD, Gordon, M. , SHELTON, Brett, C. , ZAINUL, Mohamed, A.
发明人： PASTEL, David, A. , PIECH, Garrett, A. , SHEDD, Gordon, M. , SHELTON, Brett, C. , ZAINUL, Mohamed, A.
IPC分类号： G01N21/25 , G01N21/27 , B01L3/00
摘要： A reference microplate is described herein which can be used to help calibrate and troubleshoot an optical interrogation system. In one embodiment, the reference microplate has a frame with an array of wells each of which contains an optical biosensor and each optical biosensor is at least partially coated with a substance (e.g., elastomer, optical epoxy). In another embodiment, the reference microplate in addition to having its optical biosensors at least partially covered with a substance (e.g., elastomer, optical epoxy) also has a controllable heating device attached thereto which is used to heat the optical biosensors.

8. 发明申请

WO2007019039A1 METHOD FOR INCREASING A READ-OUT SPEED OF A CCD-DETECTOR 审中-公开
标题翻译：增加CCD检测器读出速度的方法
公开(公告)号：WO2007019039A1
公开(公告)日：2007-02-15
申请号：PCT/US2006/028745
申请日：2006-07-25
申请人： CORNING INCORPORATED , PIECH, Garrett A , WEBB, Michael B
发明人： PIECH, Garrett A , WEBB, Michael B
IPC分类号： G01J3/28 , G01N21/77
CPC分类号： G01N21/7743 , G01J3/2803
摘要： A typical use of linear or two dimensional spectrometers is to expose the detector area (102) , and then shift the photo-electric charges out of the device in a serial fashion. If the illuminating signal (118) is spatially narrow relative to the size of the array, this will drive down the percent of the detector that is utilized, as only a relatively small number of pixels are used to detect the beam. The present invention proposes a method which capitalizes on this spatial under-utilization, and alters the clocking scheme to maximize the read-out speed of the pixels containing signal information. This type of clocking scheme raises the optical power saturation level of the spectrometer. Such an improvement in optical power handling is beneficial for spectrometer based detection of resonant waveguide grating biochemical binding, since in such systems the performance is frequently limited by spectrometer saturation.
摘要翻译：线性或二维光谱仪的典型用途是暴露检测器区域（102），然后将光电荷以串联方式移出设备。如果照明信号（118）相对于阵列的尺寸在空间上窄，则这将驱动所使用的检测器的百分比，因为仅使用相对较少数量的像素来检测光束。本发明提出了一种利用该空间利用不足的方法，并且改变了时钟方案以使包含信号信息的像素的读出速度最大化。这种类型的时钟方案提高了光谱仪的光功率饱和水平。光功率处理的这种改进对于谐振波导光栅生化结合的基于光谱仪的检测是有利的，因为在这样的系统中，性能常常受到光谱仪饱和度的限制。

9. 发明申请

WO2006088799A1 SINGLE MODE (SM) FIBER OPTICAL READER SYSTEM AND METHOD FOR INTERROGATING RESONANT WAVEGUIDE-GRATING SENSOR(S) 审中-公开
标题翻译：单模（SM）光纤读取器系统和谐波波导光栅传感器的混合方法（S）
公开(公告)号：WO2006088799A1
公开(公告)日：2006-08-24
申请号：PCT/US2006/005046
申请日：2006-02-13
申请人： CORNING INCORPORATED , GOLLIER, Jacques , PIECH, Garrett A
发明人： GOLLIER, Jacques , PIECH, Garrett A
IPC分类号： G01N21/47 , G01N21/77
CPC分类号： G01N21/7743
摘要： An optical reader system is described herein which has a single mode (SM) optical fiber launch/receive system that uses one or more SM optical fibers to interrogate a biosensor and does not use multimode (MM) optical fibers to interrogate the biosensor. The use of the SM optical fiber launch/receive system effectively reduces angular sensitivity, reduces unwanted system reflections, improves overall angular tolerance, and improves resonant peak reflectivity and resonant peak width. Two specific embodiments of the SM optical fiber launch/receive system are described herein which include: (1) a dual fiber collimator launch/receive system; and (2) a single fiber launch/receive system that interrogates the biosensor at a normal incidence.
摘要翻译：本文描述了一种光学读取器系统，其具有使用一个或多个SM光纤询问生物传感器并且不使用多模（MM）光纤来询问生物传感器的单模（SM）光纤发射/接收系统。使用SM光纤发射/接收系统有效地降低了角度灵敏度，减少了不必要的系统反射，提高了整体角度公差，并且提高了谐振峰值反射率和谐振峰值宽度。本文描述了SM光纤发射/接收系统的两个具体实施例，其包括：（1）双光纤准直器发射/接收系统; 和（2）以正常入射方式询问生物传感器的单纤维发射/接收系统。

10. 发明申请

WO2010075017A2 MULTI-VARIABLE CONTROL METHODS FOR OPTICAL PACKAGES 审中-公开
标题翻译：用于光学包装的多变量控制方法
公开(公告)号：WO2010075017A2
公开(公告)日：2010-07-01
申请号：PCT/US2009/067818
申请日：2009-12-14
申请人： CORNING INCORPORATED , GOLLIER, Jacques , PIECH, Garrett A , PIKULA, Dragan , RICKETTS, Daniel O
发明人： GOLLIER, Jacques , PIECH, Garrett A , PIKULA, Dragan , RICKETTS, Daniel O
IPC分类号： H01S5/0683 , H01S5/0687 , H01S5/022
CPC分类号： H01S5/0683 , G02F1/35 , G02F1/3775 , H01S5/0092 , H01S5/06256 , H01S5/0687
摘要： According to one embodiment of the present invention, an optical package comprises one or more semiconductor lasers coupled to a wavelength conversion device with adaptive optics. The optical package also comprises a package controller programmed to operate the semiconductor laser and the adaptive optics based on modulated feedback control signals supplied to the wavelength selective section of the semiconductor laser and the adaptive optics. The wavelength control signal supplied to the wavelength selective section of the semiconductor laser may be adjusted based on the modulated wavelength feedback control signal such that the response parameter of the wavelength conversion device is optimized. Similarly, the position control signals supplied to the adaptive optics may be adjusted based on the modulated feedback position control signals such that the response parameter of the wavelength conversion device is optimized.
摘要翻译：根据本发明的一个实施例，光学封装包括耦合到具有自适应光学器件的波长转换器件的一个或多个半导体激光器。光学封装还包括编程为基于提供给半导体激光器和自适应光学器件的波长选择部分的调制反馈控制信号来操作半导体激光器和自适应光学器件的封装控制器。提供给半导体激光器的波长选择部分的波长控制信号可以基于调制的波长反馈控制信号进行调整，使得波长转换器件的响应参数被优化。类似地，可以基于调制的反馈位置控制信号来调整提供给自适应光学器件的位置控制信号，使得波长转换装置的响应参数被优化。

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