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    • 2. 发明申请
    • OPTIMIZED METHOD FOR LID BIOSENSOR RESONANCE DETECTION
    • LID生物传感器共振检测的优化方法
    • WO2008057132A2
    • 2008-05-15
    • PCT/US2007/004626
    • 2007-02-20
    • CORNING INCORPORATEDGOLLIER, JacquesPIECH, Garrett, A.WEBB, Michael, BrianWU, Qi
    • GOLLIER, JacquesPIECH, Garrett, A.WEBB, Michael, BrianWU, Qi
    • G01J3/28G01N21/27
    • G01J3/28G01J3/02G01J3/0218G01J3/1895G01J3/2803G01N21/7743
    • An optical interrogation system is described herein that can interrogate a label-independent-detection (LID) biosensor and monitor a biological event on top of the biosensor without suffering from problematical parasitic reflections and/or problematical pixelation effects. In one embodiment, the optical interrogation system is capable of interrogating a biosensor and using a low pass filter algorithm to digitally remove problematic parasitic reflections contained in the spectrum of an optical resonance which makes it easier to determine whether or not a biological event occurred on the biosensor. In another embodiment, the optical interrogation system is capable of interrogating a biosensor and using an oversampling/smoothing algorithm to reduce oscillations in the estimated location of an optical resonance caused by the problematical pixelation effect which makes it easier to determine whether or not a biological event occurred on the biosensor.
    • 这里描述了一种光学询问系统,其可以询问独立于标签的检测(LID)生物传感器并监测生物传感器顶部的生物事件,而不会遭受有问题的寄生反射和/或有问题的像素化效应 。 在一个实施例中,光学询问系统能够询问生物传感器并且使用低通滤波算法来数字地去除包含在光学共振的光谱中的有问题的寄生反射,这使得更容易确定生物事件是否发生在 生物传感器。 在另一实施例中,光学询问系统能够询问生物传感器并且使用过采样/平滑算法来减少由成问题的像素效应引起的光学共振的估计位置中的振荡,这使得更容易确定生物事件 发生在生物传感器上。
    • 6. 发明申请
    • RAPID ALIGNMENT METHODS FOR OPTICAL PACKAGES
    • 用于光学包的快速对准方法
    • WO2010123988A1
    • 2010-10-28
    • PCT/US2010/031893
    • 2010-04-21
    • CORNING INCORPORATEDBLANDING, Douglass LGOLLIER, JacquesPIECH, Garrett A
    • BLANDING, Douglass LGOLLIER, JacquesPIECH, Garrett A
    • H01S3/10
    • G02F1/377G02F2001/3503G02F2001/3546H01S5/0014H01S5/0092H01S5/06821H01S5/0683
    • A method for aligning an optical package including a semiconductor laser operable to emit an output beam having a first wavelength, a wavelength conversion device operable to convert the output beam to a second wavelength and adaptive optics configured to optically couple the output beam into a waveguide portion of an input facet of the wavelength conversion device includes measuring a power of light having a first wavelength emitted by or scattered from the wavelength conversion device as the output beam is scanned over the input facet of the wavelength conversion device along a first scanning axis. A power of light emitted from the wavelength conversion device is then measured as the output beam is scanned over the input facet along a second scanning axis. A position of the second scanning axis relative to an edge of the wavelength conversion device is based on the measured power of light having the first wavelength.
    • 一种用于对准包括可操作以发射具有第一波长的输出光束的半导体激光器的光学封装的方法,可操作以将输出光束转换为第二波长的波长转换装置,以及配置为将输出光束光耦合到波导部分中的自适应光学器件 所述波长转换装置的输入面包括:测量当所述波长转换装置沿着第一扫描轴扫描所述输出光束时从所述波长转换装置发射或散射的具有第一波长的光的功率。 然后当输出光束沿着第二扫描轴在输入刻面上扫描时,测量从波长转换装置发射的光的功率。 第二扫描轴相对于波长转换装置的边缘的位置是基于测量的具有第一波长的光的功率。
    • 10. 发明申请
    • METHODS AND SYSTEMS FOR OPTIMIZING THE ALIGNMENT OF OPTICAL PACKAGES
    • 优化光学配件对准的方法和系统
    • WO2011156214A1
    • 2011-12-15
    • PCT/US2011/039006
    • 2011-06-03
    • CORNING INCORPORATEDGOLLIER, JacquesPIECH, Garrett A.RICKETTS, Daniel O.
    • GOLLIER, JacquesPIECH, Garrett A.RICKETTS, Daniel O.
    • G02B26/10G02F1/377
    • G02B26/101G02F1/377
    • A method for optimizing the alignment of an optical package includes directing a beam spot of a laser along a folded optical path and onto a waveguide portion of a wavelength conversion. The output intensity of the wavelength conversion device is measured as a position of an adjustable optical component is adjusted about a first scanning axis and a second scanning axis thereby traversing the beam spot along a first and second scan lines on the waveguide portion of the wavelength conversion device. The change in the output intensity of the wavelength conversion device is then determined based on the adjusted position of the adjustable optical component. The adjustable optical component is then positioned on the first scanning axis and the second scanning axis based on the determined changes in the output intensity of the wavelength conversion device such that the output intensity of the wavelength conversion device is maximized.
    • 用于优化光学封装的对准的方法包括将激光束的束斑沿着折叠的光路引导到波长转换的波导部分上。 测量波长转换装置的输出强度,因为可调节光学部件的位置围绕第一扫描轴和第二扫描轴进行调节,从而沿着波长转换的波导部分上的第一和第二扫描线遍及光束点 设备。 然后,基于可调节光学部件的调整位置来确定波长转换装置的输出强度的变化。 基于所确定的波长转换装置的输出强度的变化,使可调光学部件位于第一扫描轴和第二扫描轴上,使得波长转换装置的输出强度最大化。