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1. 发明申请

WO2011039230A3 DRUG DELIVERY SYSTEM, DRUG DELIVERY DEVICE, NEEDLE ASSEMBLY AND METHOD FOR PRIMING 审中-公开
标题翻译：药物递送系统，药物递送装置，针组件和用于预定的方法
公开(公告)号：WO2011039230A3
公开(公告)日：2011-06-30
申请号：PCT/EP2010064423
申请日：2010-09-29
申请人： SANOFI AVENTIS DEUTSCHLAND , KOUYOUMJIAN GAREN , VEASEY ROBERT , JONES CHRISTOPHER , MACDONALD CATHERINE ANNE , GILMORE STEPHEN , CAVE GEORGE
发明人： KOUYOUMJIAN GAREN , VEASEY ROBERT , JONES CHRISTOPHER , MACDONALD CATHERINE ANNE , GILMORE STEPHEN , CAVE GEORGE
IPC分类号： A61M5/24 , A61M5/32 , A61M5/34
CPC分类号： A61M5/34 , A61M5/002 , A61M5/1456 , A61M5/2466 , A61M5/3146 , A61M5/31525 , A61M5/31533 , A61M5/31571 , A61M5/3202 , A61M5/3293 , A61M5/345
摘要： A drug delivery system comprises a drug delivery device (22) which comprises a housing (1) and a cartridge (2). The drug delivery device (22) has a proximal end and a distal end. The drug delivery system further comprises a needle assembly (10) which is attachable to the drug delivery device (22). The needle assembly (10) and the drug delivery device (22) are configured such that the cartridge (2) is moved in the proximal direction with respect to the housing (1) when the needle assembly (10) is attached to the drug delivery device (22).
摘要翻译：药物递送系统包括药物输送装置（22），其包括壳体（1）和药筒（2）。药物输送装置（22）具有近端和远端。药物递送系统还包括可组装到药物递送装置（22）上的针组件（10）。针组件（10）和药物输送装置（22）被构造成使得当针组件（10）附接到药物递送部时，药筒（2）相对于壳体（1）沿近侧方向移动装置（22）。

2. 发明申请

WO2011039231A1 DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置
公开(公告)号：WO2011039231A1
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064424
申请日：2010-09-29
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , MACDONALD, Catherine Anne , BLACHFORD, Marcus James , HOLT, James Andrew
发明人： VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , MACDONALD, Catherine Anne , BLACHFORD, Marcus James , HOLT, James Andrew
IPC分类号： A61M5/20
CPC分类号： A61M5/20 , A61M5/3129 , A61M5/3146 , A61M2005/2073 , A61M2205/6063
摘要： A drug delivery device comprising: a device body (2), an operating member (3) which is configured to be movable relative to the device body (2) for operating the drug delivery device (1), a preventing member (4) which prevents movement of the operating member (3) relative to the device body (2) for operating the drug delivery device (1), wherein the preventing member (4) is removable to allow movement of the operating member (3) relative to the device body (2) for operating the drug delivery device (1).
摘要翻译：一种药物输送装置，包括：装置主体（2）;操作构件（3），其构造成相对于用于操作药物输送装置（1）的装置主体（2）可移动;防止构件（4），其防止操作构件（3）相对于用于操作药物输送装置（1）的装置主体（2）的运动，其中防止构件（4）是可移除的，以允许操作构件（3）相对于装置用于操作药物输送装置（1）的主体（2）。

3. 发明申请

WO2011039211A1 BUTTON MEMBER FOR OPERATING A DRIVE ASSEMBLY 审中-公开
标题翻译：用于操作驱动装置的按钮部件
公开(公告)号：WO2011039211A1
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064402
申请日：2010-09-29
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , MACDONALD, Catherine Anne , VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , LINDSAY, Adrew Mark , BAINTON, Michael
发明人： MACDONALD, Catherine Anne , VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , LINDSAY, Adrew Mark , BAINTON, Michael
IPC分类号： A61M5/315
CPC分类号： A61M5/24 , A61M5/2448 , A61M5/3146 , A61M5/31555 , A61M5/3156 , A61M5/3158 , A61M5/31593 , A61M2005/2407 , A61M2005/2492 , A61M2205/583 , A61M2205/6018
摘要： A button member (5) for operating a drive assembly (4) of a drug delivery device comprises a first portion being accessible by a user, a second portion in operative connection with the drive assembly (4), said second portion comprising a first guiding track (51) having a first track portion (511) in a first direction and a second track portion (512) in second direction, wherein the first track portion (511) is adapted to restrict the movement of the button member (5) to a substantially rotational motion, and wherein the second track portion (512) is adapted to restrict the movement of the button member (5) to an axial motion.
摘要翻译：用于操作药物递送装置的驱动组件（4）的按钮构件（5）包括可由使用者接近的第一部分，与驱动组件（4）可操作地连接的第二部分，所述第二部分包括第一引导轨道（51）在第一方向上具有第一轨道部分（511），在第二方向上具有第二轨道部分（512），其中第一轨道部分（511）适于将按钮部件（5）的移动限制为基本上旋转运动，并且其中第二轨道部分（512）适于将按钮构件（5）的移动限制为轴向运动。

4. 发明申请

WO2011039206A2 RESETTABLE DRUG DELIVERY DEVICE 审中-公开
标题翻译：可重置药物递送装置
公开(公告)号：WO2011039206A2
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064396
申请日：2010-09-29
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , PLUMPTRE, David , LINDSAY, Adrew Mark , MACDONALD, Catherine Anne , VEASEY, Robert , JONES, Christopher , KOUYOUMJIAN, Garen
发明人： PLUMPTRE, David , LINDSAY, Adrew Mark , MACDONALD, Catherine Anne , VEASEY, Robert , JONES, Christopher , KOUYOUMJIAN, Garen
IPC分类号： A61M5/315
CPC分类号： A61M5/24 , A61M5/3146 , A61M5/31501 , A61M5/31543 , A61M5/3156 , A61M5/31575 , A61M5/31585 , A61M5/31593 , A61M2005/2407 , A61M2005/2488 , A61M2005/3103 , A61M2005/3125 , A61M2005/3126 , A61M2205/581 , A61M2205/582
摘要： Drug delivery device and drive member for a drug delivery device A drive member (1 ) for driving a piston rod (5) in a drug delivery device (4) is provided. The drive member (1 ) is configured to be driven in a rotational movement by an actuating member. The drive member (1 ) comprises a track (12) for transmitting a driving load from the actuating member to the drive member (1 ). The track (12) comprises both sections running in a distal and sections running in a proximal direction of the drive member (1 ). Moreover, a drug delivery device (4) comprising such a drive member (1 ) is provided.
摘要翻译：用于药物输送装置的药物输送装置和驱动构件提供用于驱动药物输送装置（4）中的活塞杆（5）的驱动构件（1）。驱动构件（1）构造成通过致动构件在旋转运动中被驱动。驱动构件（1）包括用于将驱动载荷从致动构件传递到驱动构件（1）的轨道（12）。轨道（12）包括在远端运行的部分和沿驱动部件（1）的近端方向延伸的部分。此外，提供了包括这种驱动构件（1）的药物输送装置（4）。

5. 发明申请

WO2011039219A3 DRUG DELIVERY DEVICE, ASSEMBLY FOR A DRUG DELIVERY DEVICE AND METHOD FOR SETTING UP A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置，用于药物递送装置的组装以及用于设置药物递送装置的方法
公开(公告)号：WO2011039219A3
公开(公告)日：2011-08-11
申请号：PCT/EP2010064410
申请日：2010-09-29
申请人： SANOFI AVENTIS DEUTSCHLAND , MACDONALD CATHERINE ANNE , VEASEY ROBERT , KOUYOUMJIAN GAREN , JONES CHRISTOPHER , BAILEY ALEXANDER IAN
发明人： MACDONALD CATHERINE ANNE , VEASEY ROBERT , KOUYOUMJIAN GAREN , JONES CHRISTOPHER , BAILEY ALEXANDER IAN
IPC分类号： A61M5/24
CPC分类号： A61M5/24 , A61M5/2448 , A61M5/3146 , A61M5/31571 , A61M5/31578 , A61M2005/2073 , A61M2005/2451
摘要： The instant application is directed to an assembly for a drug delivery device which is arranged to operate in two distinct modes, a priming mode starting from a pre-priming state and a dispense mode operating in a post-priming state, and a drug delivery device comprising this assembly. The assembly comprises a dose member (2), an actuating member (3) and a piston rod (7) which is configured to act on a bung (8) of an assembled cartridge (9) containing the drug. In the pre-priming state the actuating member (3) is configured to be moved by a user such that the movement of the actuating member (3) causes a movement of the dose member (2) and such that the movement of the dose member (2) causes a movement of the piston rod (7). In the post-priming state the dose member (2) is configured to be moved by a user without causing a movement of the actuating member (3) in order to perform a set and dispense action of the drug delivery device.
摘要翻译：本申请涉及一种用于药物输送装置的组件，其被布置成以两种不同的模式操作，即从预加注状态开始的加注模式和在加注后状态下操作的分配模式，以及药物输送装置包括这个组件。该组件包括剂量构件（2），致动构件（3）和活塞杆（7），活塞杆构造成作用在组装的药筒（9）的塞子（8）上。在预启动状态下，致动构件（3）构造成由使用者移动，使得致动构件（3）的移动引起剂量构件（2）的移动并且使得剂量构件（2）引起活塞杆（7）的运动。在起动后状态中，剂量构件（2）构造成由使用者移动而不引起致动构件（3）的移动以便执行药物输送装置的设定和分配动作。

6. 发明申请

WO2011039213A3 AN ASSEMBLY OF A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置的组装
公开(公告)号：WO2011039213A3
公开(公告)日：2011-06-30
申请号：PCT/EP2010064404
申请日：2010-09-29
申请人： SANOFI AVENTIS DEUTSCHLAND , MACDONALD CATHERINE ANNE , VEASEY ROBERT , KOUYOUMJIAN GAREN , JONES CHRISTOPHER , LINDSAY ADREW MARK , BAINTON MICHAEL
发明人： MACDONALD CATHERINE ANNE , VEASEY ROBERT , KOUYOUMJIAN GAREN , JONES CHRISTOPHER , LINDSAY ADREW MARK , BAINTON MICHAEL
IPC分类号： A61M5/315
CPC分类号： A61M5/3155 , A61M2005/2073
摘要： An assembly of a drug delivery device with a longitudinal axis (L) is given, comprising a body (1) with a proximal end (2) and a distal end (3). The drug delivery device further comprises a drive assembly and a first button member (4). The drive assembly is at least partially arranged within the body (1) and is adapted to facilitate dispense of a medicinal product. The first button member (4) acts on the drive assembly to prepare the drug delivery device for dispensing the medicinal product. The first button member (4) is adapted to be detachable from the body (1) after the preparation of the drug delivery device is completed.
摘要翻译：给出了具有纵向轴线（L）的药物递送装置的组件，包括具有近端（2）和远端（3）的主体（1）。药物输送装置还包括驱动组件和第一按钮构件（4）。所述驱动组件至少部分地布置在所述主体（1）内并且适于便于分配药用产品。第一按钮构件（4）作用在驱动组件上以制备用于分配药物的药物输送装置。第一按钮构件（4）适于在药物输送装置的制备完成之后与主体（1）分离。

7. 发明申请

WO2011039216A3 DRIVE ASSEMBLY AND USE OF A SPRING IN A DRUG DELIVERY DEVICE 审中-公开
标题翻译：驱动装配和在药物递送装置中使用弹簧
公开(公告)号：WO2011039216A3
公开(公告)日：2011-06-03
申请号：PCT/EP2010064407
申请日：2010-09-29
申请人： SANOFI AVENTIS DEUTSCHLAND , VEASEY ROBERT , BILTON SIMON LEWIS , JONES CHRISTOPHER , KOUYOUMJIAN GAREN , MACDONALD CATHERINE ANNE
发明人： VEASEY ROBERT , BILTON SIMON LEWIS , JONES CHRISTOPHER , KOUYOUMJIAN GAREN , MACDONALD CATHERINE ANNE
IPC分类号： A61M5/24 , A61M5/315
CPC分类号： A61M5/3158 , A61M5/24 , A61M5/31541 , A61M5/31543 , A61M5/31555 , A61M5/31556 , A61M2005/2407 , A61M2005/2477 , A61M2005/3126
摘要： Resettable drive assembly for a drug delivery device is provided for. The resettable drive assembly may comprise a housing (10A, 10B, 10C), a piston rod (20) being rotatable and axially displaceable with respect to the housing between a proximal start position and a distal end position, a drive member (30) for distally displacing the piston rod towards the end position when dispensing a dose, and a stop member (50). The drive member is operable to interact with the piston rod for forming an unlockable first interlock, the first interlock being operable to block proximal movement of the piston rod with respect to the drive member. The stop member is operable to interact with the piston rod for forming an unlockable second interlock, the second interlock being operable to block proximal movement of the piston rod with respect to the housing. When the drive assembly is in a drive mode, the interlocks are locked such that proximal movement of the piston rod from the end position to the start position is prevented. For switching the drive assembly from the drive mode to a reset mode, the piston rod is rotatable with respect to the drive member for unlocking the first interlock and the stop member and the piston rod are rotatable with respect to each other for unlocking the second interlock. When the drive assembly is in the reset mode, the first interlock and the second interlock are unlocked such that proximal movement of the piston rod to the start position is allowed. Further, a drug delivery device and a use of a spring are provided for.
摘要翻译：提供了用于药物输送装置的可重置驱动组件。可重置的驱动组件可以包括壳体（10A，10B，10C），活塞杆（20）可在近端起始位置和远端位置之间相对于壳体旋转和轴向移动;驱动构件（30），用于当分配剂量时，将活塞杆朝向终端位置远端移动，以及止挡件（50）。驱动构件可操作以与活塞杆相互作用以形成可解锁的第一互锁，第一互锁可操作以阻止活塞杆相对于驱动构件的近端运动。止动构件可操作以与活塞杆相互作用以形成可解锁的第二互锁，所述第二互锁可操作以阻止活塞杆相对于壳体的近端运动。当驱动组件处于驱动模式时，互锁被锁定，从而防止活塞杆从终端位置到起始位置的近端运动。为了将驱动组件从驱动模式切换到复位模式，活塞杆可相对于驱动构件旋转，用于解锁第一联锁装置，并且止动构件和活塞杆可相对于彼此旋转以解锁第二联锁装置。当驱动组件处于复位模式时，第一互锁和第二联锁被解锁，使得允许活塞杆向起始位置的近端运动。此外，提供了药物递送装置和弹簧的使用。

8. 发明申请

WO2011039232A1 DRIVE MECHANISM FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置的驱动机构
公开(公告)号：WO2011039232A1
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064425
申请日：2010-09-29
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , VEASEY, Robert , PLUMPTRE, David , JONES, Christopher , KOUYOUMJIAN, Garen , MACDONALD, Catherine Anne
发明人： VEASEY, Robert , PLUMPTRE, David , JONES, Christopher , KOUYOUMJIAN, Garen , MACDONALD, Catherine Anne
IPC分类号： A61M5/315
CPC分类号： A61M5/31511 , A61M5/24 , A61M5/31505 , A61M5/31555 , A61M5/3156 , A61M5/31585 , A61M2005/2407
摘要： A lead screw (5) with a screw thread (6) is arranged in a body (1 ) along an axis (4) and coupled to a lead screw nut (7) with a drive feature (8), so that the lead screw is helically rotatable in the lead screw nut. The lead screw and the lead screw nut are provided with stop features (9) interfering with a rotation of the lead screw in the lead screw nut when a force is applied to the lead screw in an axial direction. The lead screw nut has a surface area facing a guide feature (10) of the body. This surface area has a slope (12) varying around the axis. The assembly interacts such that the lead screw nut rotates in one rotational direction when a force is applied to the lead screw in the axial direction.
摘要翻译：具有螺纹（6）的导螺杆（5）沿着轴线（4）布置在主体（1）中并且与具有驱动特征（8）的丝杠螺母（7）连接，使得导螺杆可在导螺杆螺母中螺旋转动。导向螺钉和导螺杆螺母在向丝杠沿轴向施加力时，设有阻止导螺杆螺母旋转的停止特征（9）。导螺杆螺母具有面向主体的引导特征（10）的表面区域。该表面区域具有围绕轴线变化的斜率（12）。组件相互作用，使得当在轴向方向上对导螺杆施加力时，导螺杆螺母在一个旋转方向上旋转。

9. 发明申请

WO2011039215A1 A MECHANISM FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置的机制
公开(公告)号：WO2011039215A1
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064406
申请日：2010-09-29
申请人： Sanofi-Aventis Deutschland GmbH , KOUYOUMJIAN, Garen , VEASEY, Robert , PLUMPTRE, David , JONES, Christopher , MACDONALD, Catherine Anne , JONES, Matthew
发明人： KOUYOUMJIAN, Garen , VEASEY, Robert , PLUMPTRE, David , JONES, Christopher , MACDONALD, Catherine Anne , JONES, Matthew
IPC分类号： A61M5/24
CPC分类号： A61M5/31585 , A61M5/24 , A61M5/3146 , A61M5/31555 , A61M5/3158 , A61M2005/2407 , A61M2205/6081 , A61M2207/00 , Y10T29/49826
摘要： The present invention relates to an assembly forming a piston rod for advancing a cartridge bung (44) in a drug delivery device (10), the assembly comprising a first member (20) and a second member (22) wherein in a first state, the first (20) and the second member (22) are moveable with respect to each other to adjust the length of the piston rod and wherein in a second state the first member (20) is locked in position with respect to the second member (22) in order to define a fixed length of the piston rod. Furthermore, it relates to a drug delivery device (10) comprising the assembly and to a method for assembling such a drug delivery device (10).
摘要翻译：本发明涉及一种组件，其形成用于使药液输送装置（10）中的药筒塞（44）前进的活塞杆，该组件包括第一构件（20）和第二构件（22），其中在第一状态下，第一构件（20）和第二构件（22）可相对于彼此移动以调节活塞杆的长度，并且其中在第二状态下，第一构件（20）相对于第二构件锁定就位（ 22），以便限定活塞杆的固定长度。此外，本发明涉及一种药物输送装置（10），该药物输送装置（10）包括组件以及用于组装这种药物输送装置（10）的方法。

10. 发明申请

WO2011039213A2 AN ASSEMBLY OF A DRUG DELIVERY DEVICE 审中-公开
标题翻译：药物递送装置的组装
公开(公告)号：WO2011039213A2
公开(公告)日：2011-04-07
申请号：PCT/EP2010/064404
申请日：2010-09-29
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , MACDONALD, Catherine Anne , VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , LINDSAY, Adrew Mark , BAINTON, Michael
发明人： MACDONALD, Catherine Anne , VEASEY, Robert , KOUYOUMJIAN, Garen , JONES, Christopher , LINDSAY, Adrew Mark , BAINTON, Michael
IPC分类号： A61M5/315
CPC分类号： A61M5/3155 , A61M2005/2073
摘要： An assembly of a drug delivery device with a longitudinal axis (L) is given, comprising a body (1) with a proximal end (2) and a distal end (3). The drug delivery device further comprises a drive assembly and a first button member (4). The drive assembly is at least partially arranged within the body (1) and is adapted to facilitate dispense of a medicinal product. The first button member (4) acts on the drive assembly to prepare the drug delivery device for dispensing the medicinal product. The first button member (4) is adapted to be detachable from the body (1) after the preparation of the drug delivery device is completed.
摘要翻译：给出了具有纵向轴线（L）的药物输送装置的组件，其包括具有近端（2）和远端（3）的主体（1）。药物输送装置还包括驱动组件和第一按钮构件（4）。所述驱动组件至少部分地布置在所述主体（1）内并且适于促进药品的分配。第一按钮构件（4）作用在驱动组件上以准备用于分配药品的药物输送装置。在药物输送装置的制备完成之后，第一按钮构件（4）适于可从主体（1）拆卸。

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