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1. 发明申请

WO2010147877A1 DIG-5 INSECTICIDAL CRY TOXINS 审中-公开
标题翻译： DIG-5杀虫毒素毒素
公开(公告)号：WO2010147877A1
公开(公告)日：2010-12-23
申请号：PCT/US2010/038473
申请日：2010-06-14
申请人： DOW AGROSCIENCES LLC , LIRA, Justin , NARVA, Kenneth , WOOSLEY, Aaron , LARRINUA, Ignacio , HEY, Timothy
发明人： LIRA, Justin , NARVA, Kenneth , WOOSLEY, Aaron , LARRINUA, Ignacio , HEY, Timothy
IPC分类号： C07K14/325
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/02 , C07K14/325 , Y02A40/162
摘要： DIG-5 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
摘要翻译：公开了DIG-5 Cry毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

2. 发明申请

WO2009152359A2 CONSTRUCTS FOR EXPRESSING HERBICIDE TOLERANCE GENES, RELATED PLANTS, AND RELATED TRAIT COMBINATIONS 审中-公开
标题翻译：用于表达耐药性基因，相关植物和相关TRAIT组合的结构
公开(公告)号：WO2009152359A2
公开(公告)日：2009-12-17
申请号：PCT/US2009/047080
申请日：2009-06-11
申请人： DOW AGROSCIENCES LLC , LIRA, Justin, M. , WRIGHT, Terry, R. , HEY, Timothy, D. , MOYNAHAN, Tonya, Strange , BAKER, Lisa, W.
发明人： LIRA, Justin, M. , WRIGHT, Terry, R. , HEY, Timothy, D. , MOYNAHAN, Tonya, Strange , BAKER, Lisa, W.
IPC分类号： A01H5/00
CPC分类号： C12N15/821 , C12N15/8274
摘要： The subject invention relates in part to constructs for expressing herbicide tolerance genes, related plants, and related trait combinations. Such constructs and plants comprise a gene referred to herein as DSM-2. This gene was identified in Streptomyces coelicolor (A3). The DSM-2 protein is distantly related to PAT and BAR. DSM-2 can be used as a transgenic trait to impart tolerance in plant cells and plants to the herbicidal molecules glufosinate, phosphinothricin, bialaphos, and/or the like. Introduction of this gene into a variety of plants allows for excellent levels of tolerance and/or resistance to the herbicides glufosinate, bialaphos, and other herbicides. Preferred plants include canola and soybeans. The subject invention also relates to combination of the subject herbicide tolerant crop (HTC) traits along with other traits, including other HTC traits (including but not limited to glyphosate tolerance and 2,4-D tolerance), and/or insect resistance (IR) traits in some preferred embodiments. Some preferred stacks of DSM-2 with IR traits are in tobacco and corn. Thus, various uses of DSM-2 genes are included within the scope of the subject invention. Such uses include stacking of a DSM-2 gene with one or more other transgenic traits and introduction of a DSM-2 gene individually into preferred crops.
摘要翻译：本发明部分涉及用于表达除草剂耐受性基因，相关植物和相关性状组合的构建体。这样的构建体和植物包含本文称为DSM-2的基因。该基因在天蓝色链霉菌（A3）中鉴定。 DSM-2蛋白与PAT和BAR密切相关。 DSM-2可以用作转基因性状，以将植物细胞和植物中的耐受性赋予除草剂分子草铵膦，膦丝菌素，二磷脂等。将该基因引入多种植物中可以允许对除草剂草铵膦，二磷脂和其它除草剂具有优异的耐受性和/或抗性。优选的植物包括油菜籽和大豆。本发明还涉及本发明除草剂耐受性作物（HTC）性状与其他性状（包括其他HTC性状（包括但不限于草甘膦耐受性和2,4-D耐受性））和/或昆虫抗性（IR）的组合）特征。一些优选的DSM-2与IR性状的叠层在烟草和玉米中。因此，DSM-2基因的各种用途包括在本发明的范围内。这样的用途包括将DSM-2基因与一种或多种其它转基因性状进行堆叠，并将DSM-2基因单独引入优选的作物中。

3. 发明申请

WO2005067491A3 TOXIN COMPLEX PROTEINS AND GENES FROM XENORHABDUS BOVIENII 审中-公开
标题翻译：毒素复合蛋白和XENORHABDUS BOVIENII的基因
公开(公告)号：WO2005067491A3
公开(公告)日：2006-05-18
申请号：PCT/US2004043000
申请日：2004-12-23
申请人： DOW AGROSCIENCES LLC , APEL-BIRKHOLD PATRICIA C , HEY TIMOTHY D , SHEETS JOEL J , MEADE THOMAS , LI ZE SHENG , LIRA JUSTIN M , RUSSELL SEAN M , THOMPSON ROBIN L , MITCHELL JON C , FENCIL KRISTIN
发明人： APEL-BIRKHOLD PATRICIA C , HEY TIMOTHY D , SHEETS JOEL J , MEADE THOMAS , LI ZE SHENG , LIRA JUSTIN M , RUSSELL SEAN M , THOMPSON ROBIN L , MITCHELL JON C , FENCIL KRISTIN
IPC分类号： C12N15/31 , A01H1/00 , A01H5/00 , A01N63/00 , A01N63/02 , C07H21/04 , C07K14/24 , C12N5/04 , C12N15/00 , C12N15/03 , C12N15/05 , C12N15/08 , C12N15/10 , C12N15/32 , C12N15/82 , C12P21/02
CPC分类号： C12N15/8286 , A01N63/00 , A01N63/02 , C07H21/04 , C07K14/24 , C12N15/8279 , Y02A40/162 , Y10S530/825
摘要： The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus bovienii strain ILM104.
摘要翻译：本发明涉及新型异戊酰梭菌毒素复合物（TC）蛋白质和编码这些蛋白质的基因。更具体地，本发明涉及从Xenorhabdus bovienii菌株ILM104获得的TC基因和蛋白质。

4. 发明申请

WO2010147880A3 DIG-11 INSECTICIDAL CRY TOXINS 审中-公开
标题翻译： DIG-11杀虫毒素毒素
公开(公告)号：WO2010147880A3
公开(公告)日：2014-04-03
申请号：PCT/US2010038483
申请日：2010-06-14
申请人： DOW AGROSCIENCES LLC , LIRA JUSTIN , NARVA KENNETH , WOOSLEY AARON , LARRINUA IGNACIO , HEY TIMOTHY
发明人： LIRA JUSTIN , NARVA KENNETH , WOOSLEY AARON , LARRINUA IGNACIO , HEY TIMOTHY
IPC分类号： C12P21/06
CPC分类号： C12N15/8286 , A01N63/02 , Y02A40/162
摘要： DIG-11 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
摘要翻译：公开了DIG-11 Cry毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

5. 发明申请

WO2010147880A2 DIG-11 INSECTICIDAL CRY TOXINS 审中-公开
标题翻译： DIG-11杀虫毒素毒素
公开(公告)号：WO2010147880A2
公开(公告)日：2010-12-23
申请号：PCT/US2010/038483
申请日：2010-06-14
申请人： DOW AGROSCIENCES LLC , LIRA, Justin , NARVA, Kenneth , WOOSLEY, Aaron , LARRINUA, Ignacio , HEY, Timothy
发明人： LIRA, Justin , NARVA, Kenneth , WOOSLEY, Aaron , LARRINUA, Ignacio , HEY, Timothy
IPC分类号： A01N63/02 , C07K14/32 , A01H5/00 , C07H21/04 , A01P1/00 , A01P7/04
CPC分类号： C12N15/8286 , A01N63/02 , Y02A40/162
摘要： DIG-11 Cry toxins, polynucleotides encoding such toxins, use of such toxins to control pests, and transgenic plants that produce such toxins are disclosed.
摘要翻译：公开了DIG-11 Cry毒素，编码这种毒素的多核苷酸，使用这些毒素来控制害虫，以及产生这种毒素的转基因植物。

6. 发明申请

WO2009152359A3 CONSTRUCTS FOR EXPRESSING HERBICIDE TOLERANCE GENES, RELATED PLANTS, AND RELATED TRAIT COMBINATIONS 审中-公开
标题翻译：用于表达耐药性基因，相关植物和相关TRAIT组合的结构
公开(公告)号：WO2009152359A3
公开(公告)日：2010-02-04
申请号：PCT/US2009047080
申请日：2009-06-11
申请人： DOW AGROSCIENCES LLC , LIRA JUSTIN M , WRIGHT TERRY R , HEY TIMOTHY D , MOYNAHAN TONYA STRANGE , BAKER LISA W
发明人： LIRA JUSTIN M , WRIGHT TERRY R , HEY TIMOTHY D , MOYNAHAN TONYA STRANGE , BAKER LISA W
IPC分类号： A01H5/00 , C12N15/87
CPC分类号： C12N15/821 , C12N15/8274
摘要： Constructs for expressing herbicide tolerance genes, related plants, and related trait combinations, said constructs comprise a gene referred to herein as DSM-2 identified in Streptomyces coelicolor (A3). The DSM-2 protein is distantly related to PAT and BAR DSM-2 can be used as a transgenic trait to impart tolerance in plant cells and plants to the herbicidal molecules glufosinate, phosphinothricin, bialaphos, and/or the like. The subject invention also relates to combination of the subject herbicide tolerant crop (HTC) traits along wit other HTC traits and/or insect resistance (IR) traits.
摘要翻译：用于表达除草剂耐受基因，相关植物和相关性状组合的构建体，所述构建体包含本文称为在天蓝色链霉菌（A3）中鉴定的DSM-2的基因。 DSM-2蛋白与PAT有很大关系，BAR DSM-2可用作转基因性状，以将植物细胞和植物中的耐受性赋予除草剂分子草铵膦，膦丝菌素，双丙二酸等。本发明还涉及与其他HTC性状和/或昆虫抗性（IR）性状一起的主体除草剂耐受性作物（HTC）性状的组合。

7. 发明申请

WO2008141154A3 NOVEL HERBICIDE RESISTANCE GENES 审中-公开
标题翻译：新型抗除草剂基因
公开(公告)号：WO2008141154A3
公开(公告)日：2009-02-05
申请号：PCT/US2008063212
申请日：2008-05-09
申请人： DOW AGROSCIENCES LLC , LIRA JUSTIN M , SNODDERLEY ERIKA MEGAN , ROBINSON ANDREW E , WRIGHT TERRY R , MERLO DONALD J
发明人： LIRA JUSTIN M , SNODDERLEY ERIKA MEGAN , ROBINSON ANDREW E , WRIGHT TERRY R , MERLO DONALD J
IPC分类号： C12N15/82 , C12Q1/68
CPC分类号： C12N15/8274 , C12N9/0004 , C12N15/8275
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D, but also to a pyridyloxyacetate herbicide. The subject invention also includes plants that produce one or more enzymes of the subject invention "stacked" together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-13 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
摘要翻译：本发明提供不仅对2,4-D有抗性的新型植物，而且还涉及吡啶氧基乙酸酯除草剂。本发明还包括与一种或多种其它除草剂抗性基因一起产生本发明一种或多种酶“堆叠”的植物。本发明能够以新的方式使用除草剂的新型组合。此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。根据本发明使用的优选酶和基因在本文中称为AAD-13（丙烯酰氧基烷酸酯加氧酶）。这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。

8. 发明申请

WO2010120452A1 DIG-3 INSECTICIDAL CRY TOXINS 审中-公开
标题翻译： DIG-3杀虫剂毒素
公开(公告)号：WO2010120452A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/028381
申请日：2010-03-24
申请人： DOW AGROSCIENCES LLC , LIRA, Justin , BUTLER, Holly , SMITH, Doug , NARVA, Kenneth , MEADE, Thomas
发明人： LIRA, Justin , BUTLER, Holly , SMITH, Doug , NARVA, Kenneth , MEADE, Thomas
IPC分类号： C07K14/325 , C12N15/82
CPC分类号： A01N43/50 , C07K14/325 , C12N15/8286 , Y02A40/162
摘要： DIG-3 Cry toxins, polynucleotides encoding such toxins, and transgenic plants that produce such toxins are useful to control insect pests.
摘要翻译： DIG-3 Cry毒素，编码这种毒素的多核苷酸和产生这种毒素的转基因植物可用于防治害虫。

9. 发明申请

WO2008070845A3 NOVEL SELECTABLE MARKER GENES 审中-公开
公开(公告)号：WO2008070845A3
公开(公告)日：2008-06-12
申请号：PCT/US2007/086813
申请日：2007-12-07
申请人： DOW AGROSCIENCES LLC , LIRA, Justin, M. , WRIGHT, Terry, R. , RUSSELL, Sean, M. , MERLO, Donald, J. , WEBB, Steven, Robert , ARNOLD, Nicole, L. , ROBINSON, Andrew, E. , SMITH, Kelley, A.
发明人： LIRA, Justin, M. , WRIGHT, Terry, R. , RUSSELL, Sean, M. , MERLO, Donald, J. , WEBB, Steven, Robert , ARNOLD, Nicole, L. , ROBINSON, Andrew, E. , SMITH, Kelley, A.
IPC分类号： C12N1/21 , C12N15/82 , A01H1/00
摘要： The subject invention relates to a novel gene referred to herein as DSM-2 . This gene was identified in Sterptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins, DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes are as selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.

10. 发明申请

WO2007053482A2 NOVEL HERBICIDE RESISTANCE GENES 审中-公开
标题翻译：新型抗除草剂基因
公开(公告)号：WO2007053482A2
公开(公告)日：2007-05-10
申请号：PCT/US2006/042133
申请日：2006-10-27
申请人： DOW AGROSCIENCES LLC , WRIGHT, Terry, R. , LIRA, Justin, M. , WALSH, Terence, Anthony , MERLO, Donald, J. , JAYAKUMAR, Pon, Samuel , LIN, Gaofeng
发明人： WRIGHT, Terry, R. , LIRA, Justin, M. , WALSH, Terence, Anthony , MERLO, Donald, J. , JAYAKUMAR, Pon, Samuel , LIN, Gaofeng
IPC分类号： A01H5/00
CPC分类号： C12N15/8274 , A01N39/04 , C12N9/0069 , C12N9/0071 , C12N15/8275 , C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , C12Y113/11
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention "stacked" together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 ( A ryloxy A lkanoate D ioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
摘要翻译：本发明提供了不仅对2,4-D有抗性的新型植物，而且还涉及吡啶氧基乙酸酯除草剂。迄今为止，没有任何期望或建议，通过引入单一基因可以产生具有这两种有利性质的植物。本发明还包括与一种或多种其它除草剂抗性基因一起产生本发明一种或多种酶“堆叠”的植物。本发明能够以新的方式使用除草剂的新型组合。此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。根据本发明使用的优选酶和基因在本文中称为AAD-12（丙烯酰氧基烷酸酯加氧酶）。这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。

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