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1. 发明申请

WO2008070845A3 NOVEL SELECTABLE MARKER GENES 审中-公开
公开(公告)号：WO2008070845A3
公开(公告)日：2008-06-12
申请号：PCT/US2007/086813
申请日：2007-12-07
申请人： DOW AGROSCIENCES LLC , LIRA, Justin, M. , WRIGHT, Terry, R. , RUSSELL, Sean, M. , MERLO, Donald, J. , WEBB, Steven, Robert , ARNOLD, Nicole, L. , ROBINSON, Andrew, E. , SMITH, Kelley, A.
发明人： LIRA, Justin, M. , WRIGHT, Terry, R. , RUSSELL, Sean, M. , MERLO, Donald, J. , WEBB, Steven, Robert , ARNOLD, Nicole, L. , ROBINSON, Andrew, E. , SMITH, Kelley, A.
IPC分类号： C12N1/21 , C12N15/82 , A01H1/00
摘要： The subject invention relates to a novel gene referred to herein as DSM-2 . This gene was identified in Sterptomyces coelicolor A3. The DSM-2 protein is distantly related to PAT and BAR. The subject invention also provides plant-optimized genes encoding DSM-2 proteins, DSM-2 can be used as a transgenic trait to impart tolerance in plants and plant cells to the herbicides glufosinate and bialaphos. One preferred use of the subject genes are as selectable markers. The use of this gene as a selectable marker in a bacterial system can increase efficiency for plant transformations. Use of DSM-2 as the sole selection marker eliminates the need for an additional medicinal antibiotic marker (such as ampicillin resistance) during cloning. Various other uses are also possible according to the subject invention.

2. 发明申请

WO2008141154A2 NOVEL HERBICIDE RESISTANCE GENES 审中-公开
标题翻译：新型抗除草剂基因
公开(公告)号：WO2008141154A2
公开(公告)日：2008-11-20
申请号：PCT/US2008/063212
申请日：2008-05-09
申请人： DOW AGROSCIENCES LLC , LIRA, Justin, M. , SNODDERLEY, Erika, Megan , ROBINSON, Andrew, E. , WRIGHT, Terry, R. , MERLO, Donald, J.
发明人： LIRA, Justin, M. , SNODDERLEY, Erika, Megan , ROBINSON, Andrew, E. , WRIGHT, Terry, R. , MERLO, Donald, J.
IPC分类号： A01H5/00
CPC分类号： C12N15/8274 , C12N9/0004 , C12N15/8275
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D, but also to a pyridyloxyacetate herbicide. The subject invention also includes plants that produce one or more enzymes of the subject invention "stacked" together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-13 (AryloxyAlkanoate Dioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
摘要翻译：本发明提供了不仅对2,4-D有抗性的新型植物，而且还涉及吡啶氧基乙酸酯除草剂。本发明还包括与一种或多种其它除草剂抗性基因一起产生本发明一种或多种酶“堆叠”的植物。本发明能够以新的方式使用除草剂的新型组合。此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。根据本发明使用的优选酶和基因在本文中称为AAD-13（丙烯酰氧基烷酸酯加氧酶）。这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。

3. 发明申请

WO2007053482A2 NOVEL HERBICIDE RESISTANCE GENES 审中-公开
标题翻译：新型抗除草剂基因
公开(公告)号：WO2007053482A2
公开(公告)日：2007-05-10
申请号：PCT/US2006/042133
申请日：2006-10-27
申请人： DOW AGROSCIENCES LLC , WRIGHT, Terry, R. , LIRA, Justin, M. , WALSH, Terence, Anthony , MERLO, Donald, J. , JAYAKUMAR, Pon, Samuel , LIN, Gaofeng
发明人： WRIGHT, Terry, R. , LIRA, Justin, M. , WALSH, Terence, Anthony , MERLO, Donald, J. , JAYAKUMAR, Pon, Samuel , LIN, Gaofeng
IPC分类号： A01H5/00
CPC分类号： C12N15/8274 , A01N39/04 , C12N9/0069 , C12N9/0071 , C12N15/8275 , C12Q1/6895 , C12Q2600/13 , C12Q2600/158 , C12Y113/11
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D, but also to pyridyloxyacetate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention "stacked" together with one or more other herbicide resistance genes. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the development of, and controlling, strains of weeds that are resistant to one or more herbicides such as glyphosate. The preferred enzyme and gene for use according to the subject invention are referred to herein as AAD-12 ( A ryloxy A lkanoate D ioxygenase). This highly novel discovery is the basis of significant herbicide tolerant crop trait and selectable marker opportunities.
摘要翻译：本发明提供了不仅对2,4-D有抗性的新型植物，而且还涉及吡啶氧基乙酸酯除草剂。迄今为止，没有任何期望或建议，通过引入单一基因可以产生具有这两种有利性质的植物。本发明还包括与一种或多种其它除草剂抗性基因一起产生本发明一种或多种酶“堆叠”的植物。本发明能够以新的方式使用除草剂的新型组合。此外，本发明提供了防止对一种或多种除草剂如草甘膦具有抗性的杂草的发育和控制菌株的新方法。根据本发明使用的优选酶和基因在本文中称为AAD-12（丙烯酰氧基烷酸酯加氧酶）。这种高度新颖的发现是显着的除草剂耐受性作物性状和选择性标记机会的基础。

4. 发明申请

WO2005107437A2 NOVEL HERBICIDE RESISTANCE GENES 审中-公开
标题翻译：新型抗除草剂基因
公开(公告)号：WO2005107437A2
公开(公告)日：2005-11-17
申请号：PCT/US2005/014737
申请日：2005-05-02
申请人： DOW AGROSCIENCES LLC , WRIGHT, Terry, R. , LIRA, Justin, M. , MERLO, Donald, J. , HOPKINS, Nicole
发明人： WRIGHT, Terry, R. , LIRA, Justin, M. , MERLO, Donald, J. , HOPKINS, Nicole
IPC分类号： A01H5/00
CPC分类号： C12N15/8274 , A01N37/38 , A01N43/60 , A01N57/20 , C12N9/0069 , C12N9/0071 , C12N15/8209 , C12N15/8241 , C12N15/8247 , C12N15/8249 , C12N15/8255 , C12N15/8261 , C12N15/8271 , C12N15/8273 , C12N15/8275 , C12N15/8282 , C12N15/8283 , C12N15/8286
摘要： The subject invention provides novel plants that are not only resistant to 2,4-D and other phenoxy auxin herbicides, but also to aryloxyphenoxypropionate herbicides. Heretofore, there was no expectation or suggestion that a plant with both of these advantageous properties could be produced by the introduction of a single gene. The subject invention also includes plants that produce one or more enzymes of the subject invention alone or "stacked" together with another herbicide resistance gene, preferably a glyphosate. resistance gene, so as to provide broader and more robust weed control, increased treatment flexibility, and improved herbicide resistance management options. More specifically, preferred enzymes and genes for use according to the subject invention are referred to herein as AAD (aryloxyalkanoate dioxygenase) genes and proteins. No α-ketoglutarate-dependent dioxygenase enzyme has previously been reported to have the ability to degrade herbicides of different chemical classes and modes of action. This highly novel discovery is the basis of significant herbicide tolerant crop trait opportunities as well as development of selectable marker technology. The subject invention also includes related methods of controlling weeds. The subject invention enables novel combinations of herbicides to be used in new ways. Furthermore, the subject invention provides novel methods of preventing the formation of, and controlling, weeds that are resistant (or naturally more tolerant) to one or more herbicides such as glyphosate.
摘要翻译：本发明提供了不仅对2,4-D和其它苯氧基生长素除草剂具有抗性的新型植物，而且还涉及芳氧基苯氧基丙酸酯除草剂。迄今为止，没有任何期望或建议，通过引入单个基因可以产生具有这两个这些有利性质的植物。本发明还包括单独产生一种或多种本发明的酶或与其它除草剂抗性基因，优选草甘膦一起“堆叠”的植物。抗性基因，以提供更广泛和更强大的杂草控制，增加的治疗灵活性和改进的除草剂抗性管理选择。更具体地，根据本发明使用的优选的酶和基因在本文中被称为AAD（芳氧基链烷酸酯加氧酶）基因和蛋白质。据报道，没有α-酮戊二酸依赖性双加氧酶具有降解不同化学类别和作用模式的除草剂的能力。这种高度新颖的发现是显着的除草剂耐受性作物性状机会的基础以及可选择标记技术的发展。本发明还包括控制杂草的相关方法。本发明能够以新的方式使用除草剂的新型组合。此外，本发明提供了防止形成和控制对一种或多种除草剂（例如草甘膦）具有抗性（或天然更耐受）的杂草的新方法。

5. 发明申请

WO2009152359A2 CONSTRUCTS FOR EXPRESSING HERBICIDE TOLERANCE GENES, RELATED PLANTS, AND RELATED TRAIT COMBINATIONS 审中-公开
标题翻译：用于表达耐药性基因，相关植物和相关TRAIT组合的结构
公开(公告)号：WO2009152359A2
公开(公告)日：2009-12-17
申请号：PCT/US2009/047080
申请日：2009-06-11
申请人： DOW AGROSCIENCES LLC , LIRA, Justin, M. , WRIGHT, Terry, R. , HEY, Timothy, D. , MOYNAHAN, Tonya, Strange , BAKER, Lisa, W.
发明人： LIRA, Justin, M. , WRIGHT, Terry, R. , HEY, Timothy, D. , MOYNAHAN, Tonya, Strange , BAKER, Lisa, W.
IPC分类号： A01H5/00
CPC分类号： C12N15/821 , C12N15/8274
摘要： The subject invention relates in part to constructs for expressing herbicide tolerance genes, related plants, and related trait combinations. Such constructs and plants comprise a gene referred to herein as DSM-2. This gene was identified in Streptomyces coelicolor (A3). The DSM-2 protein is distantly related to PAT and BAR. DSM-2 can be used as a transgenic trait to impart tolerance in plant cells and plants to the herbicidal molecules glufosinate, phosphinothricin, bialaphos, and/or the like. Introduction of this gene into a variety of plants allows for excellent levels of tolerance and/or resistance to the herbicides glufosinate, bialaphos, and other herbicides. Preferred plants include canola and soybeans. The subject invention also relates to combination of the subject herbicide tolerant crop (HTC) traits along with other traits, including other HTC traits (including but not limited to glyphosate tolerance and 2,4-D tolerance), and/or insect resistance (IR) traits in some preferred embodiments. Some preferred stacks of DSM-2 with IR traits are in tobacco and corn. Thus, various uses of DSM-2 genes are included within the scope of the subject invention. Such uses include stacking of a DSM-2 gene with one or more other transgenic traits and introduction of a DSM-2 gene individually into preferred crops.
摘要翻译：本发明部分涉及用于表达除草剂耐受性基因，相关植物和相关性状组合的构建体。这样的构建体和植物包含本文称为DSM-2的基因。该基因在天蓝色链霉菌（A3）中鉴定。 DSM-2蛋白与PAT和BAR密切相关。 DSM-2可以用作转基因性状，以将植物细胞和植物中的耐受性赋予除草剂分子草铵膦，膦丝菌素，二磷脂等。将该基因引入多种植物中可以允许对除草剂草铵膦，二磷脂和其它除草剂具有优异的耐受性和/或抗性。优选的植物包括油菜籽和大豆。本发明还涉及本发明除草剂耐受性作物（HTC）性状与其他性状（包括其他HTC性状（包括但不限于草甘膦耐受性和2,4-D耐受性））和/或昆虫抗性（IR）的组合）特征。一些优选的DSM-2与IR性状的叠层在烟草和玉米中。因此，DSM-2基因的各种用途包括在本发明的范围内。这样的用途包括将DSM-2基因与一种或多种其它转基因性状进行堆叠，并将DSM-2基因单独引入优选的作物中。

6. 发明申请

WO2005067491A2 TOXIN COMPLEX PROTEINS AND GENES FROM XENORHABDUS BOVIENII 审中-公开
标题翻译：毒素复合蛋白和XENORHABDUS BOVIENII的基因
公开(公告)号：WO2005067491A2
公开(公告)日：2005-07-28
申请号：PCT/US2004/043000
申请日：2004-12-23
申请人： DOW AGROSCIENCES LLC , APEL-BIRKHOLD, Patricia, C. , HEY, Timothy, D. , SHEETS, Joel, J. , MEADE, Thomas , LI, Ze, Sheng , LIRA, Justin, M. , RUSSELL, Sean, M. , THOMPSON, Robin, L. , MITCHELL, Jon, C. , FENCIL, Kristin
发明人： APEL-BIRKHOLD, Patricia, C. , HEY, Timothy, D. , SHEETS, Joel, J. , MEADE, Thomas , LI, Ze, Sheng , LIRA, Justin, M. , RUSSELL, Sean, M. , THOMPSON, Robin, L. , MITCHELL, Jon, C. , FENCIL, Kristin
IPC分类号： A01H1/00 , A01H5/00 , A01N63/00 , A01N63/02 , C07H21/04 , C07K14/24 , C12N5/04 , C12N15/82
CPC分类号： C12N15/8286 , A01N63/00 , A01N63/02 , C07H21/04 , C07K14/24 , C12N15/8279 , Y02A40/162 , Y10S530/825
摘要： The subject invention relates to novel Xenorhabdus toxin complex (TC) proteins and genes that encode these proteins. More specifically, the subject invention relates to TC genes and proteins obtainable from Xenorhabdus bovienii strain ILM104.
摘要翻译：本发明涉及新型异戊酰梭菌毒素复合物（TC）蛋白质和编码这些蛋白质的基因。更具体地，本发明涉及从Xenorhabdus bovienii菌株ILM104获得的TC基因和蛋白质。

7. 发明申请

WO2013116758A1 SYNTHETIC BRASSICA-DERIVED CHLOROPLAST TRANSIT PEPTIDES 审中-公开
标题翻译：合成黄铜衍生氯离子通道蛋白
公开(公告)号：WO2013116758A1
公开(公告)日：2013-08-08
申请号：PCT/US2013/024482
申请日：2013-02-01
申请人： DOW AGROSCIENCES LLC
发明人： LIRA, Justin, M. , CICCHILLO, Robert, M. , YERKES, Carla , ROBINSON, Andrew, E.
IPC分类号： A01H5/00 , C12N15/29 , C12N15/62 , C12N15/82 , C07K19/00
CPC分类号： C12N9/1092 , A01N57/20 , C07K14/415 , C07K2319/08 , C12N9/0069 , C12N9/0071 , C12N9/1085 , C12N9/96 , C12N15/62 , C12N15/8205 , C12N15/8209 , C12N15/8214 , C12N15/8221 , C12N15/8241 , C12N15/8245 , C12N15/8247 , C12N15/8274 , C12N15/8275 , C12N15/8281 , C12N15/8283 , C12N15/8286 , C12Y113/00 , C12Y114/11 , C12Y205/01019 , Y02A40/162
摘要： This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.
摘要翻译：本公开涉及将肽，多肽和蛋白质靶向含有质体的细胞的质体的组合物和方法。在一些实施方案中，本公开涉及可将多肽导向质体的叶绿体转运肽，以及编码该多肽的核酸分子。在一些实施方案中，本公开涉及用于生产包含叶绿体转运肽的转基因植物材料（例如，转基因植物）的方法，以及由这些方法生产的植物材料以及由其生产的植物商品。

8. 发明申请

WO2013158766A1 SYNTHETIC BRASSICA-DERIVED CHLOROPLAST TRANSIT PEPTIDES 审中-公开
标题翻译：合成黄铜衍生氯离子通道蛋白
公开(公告)号：WO2013158766A1
公开(公告)日：2013-10-24
申请号：PCT/US2013/036980
申请日：2013-04-17
申请人： DOW AGROSCIENCES LLC
发明人： LIRA, Justin, M. , CICCHILLO, Robert M. , YERKES, Carla , ROBINSON, Andrew E.
IPC分类号： A01H5/00 , C12N15/29 , C07K19/00 , C12N15/63 , C12N15/82
CPC分类号： C12N15/8275 , C07K2319/00 , C12N15/8221
摘要： This disclosure concerns compositions and methods for targeting peptides, polypeptides, and proteins to plastids of plastid-containing cells. In some embodiments, the disclosure concerns chloroplast transit peptides that may direct a polypeptide to a plastid, and nucleic acid molecules encoding the same. In some embodiments, the disclosure concerns methods for producing a transgenic plant material (e.g., a transgenic plant) comprising a chloroplast transit peptide, as well as plant materials produced by such methods, and plant commodity products produced therefrom.
摘要翻译：本公开涉及将肽，多肽和蛋白质靶向含质体细胞的质体的组合物和方法。在一些实施方案中，本公开涉及可将多肽导向质体的叶绿体转运肽，以及编码该多肽的核酸分子。在一些实施方案中，本公开涉及用于生产包含叶绿体转运肽的转基因植物材料（例如，转基因植物）的方法，以及由这些方法生产的植物材料以及由其生产的植物商品。

9. 发明申请

WO2013116782A1 NOVEL CLASS OF GLYPHOSATE RESISTANCE GENES 审中-公开
标题翻译：新一代的抗糖耐性基因
公开(公告)号：WO2013116782A1
公开(公告)日：2013-08-08
申请号：PCT/US2013/024511
申请日：2013-02-01
申请人： DOW AGROSCIENCES LLC
发明人： LIRA, Justin, M. , CICCHILLO, Robert, M. , NAIR, Satish, K.
IPC分类号： A01H5/00 , C12N15/29 , C12N15/82
CPC分类号： C12N9/1092 , A01N57/20 , C07K14/415 , C07K2319/08 , C12N9/0069 , C12N9/0071 , C12N9/1085 , C12N9/96 , C12N15/62 , C12N15/8205 , C12N15/8209 , C12N15/8214 , C12N15/8221 , C12N15/8241 , C12N15/8245 , C12N15/8247 , C12N15/8274 , C12N15/8275 , C12N15/8281 , C12N15/8283 , C12N15/8286 , C12Y113/00 , C12Y114/11 , C12Y205/01019 , Y02A40/162
摘要： The present disclosure relates to a novel class of EPSPS enzymes, and nucleic acids useful in encoding the same.
摘要翻译：本公开涉及一类新颖的EPSPS酶和用于编码它们的核酸。

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