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1. 发明申请

WO2012018303A1 CORNEAL GRAFT EVALUATION BASED ON OPTICAL COHERENCE TOMOGRAPHY IMAGE 审中-公开
标题翻译：基于光学相干图像的角膜评估
公开(公告)号：WO2012018303A1
公开(公告)日：2012-02-09
申请号：PCT/SG2011/000271
申请日：2011-08-03
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , SINGAPORE HEALTH SERVICES PTE LTD , LEE, Beng Hai , CHENG, Jun , LIU, Jiang , WONG, Wing Kee Damon , TAN, Ngan Meng , MEHTA, Jodhbir Singh , TAN, Tian Hwee Donald , WONG, Tien Yin
发明人： LEE, Beng Hai , CHENG, Jun , LIU, Jiang , WONG, Wing Kee Damon , TAN, Ngan Meng , MEHTA, Jodhbir Singh , TAN, Tian Hwee Donald , WONG, Tien Yin
IPC分类号： A61B3/107 , A61F9/00 , A61B3/10 , A61B3/00 , G06T7/60
CPC分类号： G06T7/0012 , A61B3/102 , A61F2/142 , G06T7/12 , G06T7/149 , G06T2207/10101 , G06T2207/30041
摘要： An OCT image of an eye which has been subject to a DSAEK corneal transplant, in which a Descement's membrane in the cornea has been replaced by a graft, is processed to identify the outline of the graft. The process includes the steps of: computationally extracting the boundary of the cornea including the graft; computationally detecting the corners of the graft; computationally extracting points on the boundary between the graft and the original cornea; and computationally fitting the points on the boundary between the graft and the original cornea smoothly into a curve. The outline of the graft is then displayed. A graft profile may be generated, indicating the thickness of the graft at each point along its length.
摘要翻译：已经进行DSAEK角膜移植的眼睛的OCT图像被处理以识别移植物的轮廓，其中角膜中的Descement膜被移植物代替。该过程包括以下步骤：计算提取包括移植物的角膜的边界; 计算检测移植物的角部; 在移植物和原始角膜之间的边界上计算提取点; 并将计算上将移植物和原始角膜之间的边界点拟合成曲线。然后显示移植物的轮廓。可以产生移植物轮廓，指示沿其长度的每个点处移植物的厚度。

2. 发明申请

WO2008008046A1 METHOD AND SYSTEM FOR MULTI-OBJECT TRACKING 审中-公开
标题翻译：用于多目标跟踪的方法和系统
公开(公告)号：WO2008008046A1
公开(公告)日：2008-01-17
申请号：PCT/SG2007/000206
申请日：2007-07-11
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , LI, Liyuan , LUO, Ruijiang , MA, Ruihua , LEMAN, Karianto , KUMAR, Pankaj , LEE, Beng Hai , HUANG, Welmin
发明人： LI, Liyuan , LUO, Ruijiang , MA, Ruihua , LEMAN, Karianto , KUMAR, Pankaj , LEE, Beng Hai , HUANG, Welmin
IPC分类号： G06K9/00
CPC分类号： H04N7/18 , G06K9/00771 , G06K9/32 , G06K9/38 , G06K2009/3291 , G06T5/50 , G06T7/11 , G06T7/174 , G06T7/194 , G06T7/254 , G06T2207/10016 , G06T2207/20081
摘要： A method and system for multi-object tracking in a video signal. The method comprises the steps of receiving first and second segmented images of two consecutive frames of the video signal respectively, at least one of the first and second segmented images including one or more foreground regions, each foreground region corresponding to one or more objects to be tracked; generating one or more directed acrylic graphs (DAGs) for zero or more parent nodes in the first segmented image and zero to more child nodes in the second segmented images, each DAG including at least one parent or child node; and for each parent node having two or more child nodes, a) sorting the corresponding objects of the foreground region contributing to said each parent node according to estimated depth in said first image; b) assigning the corresponding object having the lowest depth to one of the child nodes of said each parent node; c) removing a visual content of the assigned corresponding object from the visual data associated with said one child node; and iterating steps b) to c) in order of increasing depth of the corresponding objects for assigning all corresponding objects to the two or more child nodes; and then for each child node having only one corresponding object assigned thereto, update a state and the visual content of said one object based on the second image; for each child node having two or more corresponding objects assigned thereto, d) sorting the corresponding objects according to estimated depth in said ech child node in said second image; e) applying a means-shift calculation to locate the corresponding object having the lowest depth in said each child node; f) updating the state and the visual content of the located corresponding object based on the second image; g) removing the updated visual content of the located corresponding object from the visual data associated with said each child node; and iterating steps e) to g) in order of increasing depth of the corresponding objects for locating all corresponding objects in a corresponding region of said each child node.
摘要翻译：一种用于视频信号中多目标跟踪的方法和系统。该方法包括以下步骤：分别接收视频信号的两个连续帧的第一和第二分割图像，第一和第二分割图像中的至少一个包括一个或多个前景区域，每个前景区域对应于一个或多个对象跟踪; 为所述第一分割图像中的零个或多个父节点生成一个或多个定向丙烯酸图（DAG），并且在所述第二分割图像中生成零到更多子节点，每个DAG包括至少一个父节点或子节点; 并且对于具有两个或更多个子节点的每个父节点，a）根据所述第一图像中的估计深度对对所述每个父节点贡献的前景区域的对应对象进行排序; b）将具有最低深度的相应对象分配给所述每个父节点的子节点之一; c）从与所述一个子节点相关联的视觉数据中去除所分配的对应对象的视觉内容; 并且按照对应对象的深度增加的顺序迭代步骤b）至c），以将所有对应的对象分配给两个或多个子节点; 然后对于仅分配了一个对应对象的每个子节点，基于第二图像更新所述一个对象的状态和视觉内容; 对于具有分配给其的两个或更多个对应对象的每个子节点，d）根据所述第二图像中所述ech子节点中估计的深度对相应对象进行排序; e）应用平均移位计算来定位所述每个子节点中具有最低深度的相应对象; f）基于第二图像来更新所定位的相应对象的状态和视觉内容; g）从与所述每个子节点相关联的视觉数据中去除所定位的对应对象的更新的可视内容; 以及迭代步骤e）至g）按照用于定位所述每个子节点的对应区域中的所有相应对象的相应对象的深度的顺序。

3. 发明申请

WO2011108995A1 AUTOMATIC ANALYSIS OF IMAGES OF THE ANTERIOR CHAMBER OF AN EYE 审中-公开
标题翻译：眼睛前庭的图像自动分析
公开(公告)号：WO2011108995A1
公开(公告)日：2011-09-09
申请号：PCT/SG2011/000088
申请日：2011-03-04
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , SINGAPORE HEALTH SERVICES PTE LTD , CHENG, Jun , LEE, Beng Hai , LIU, Jiang , AUNG, Tin , MANI, Baskaran , WONG, Tien Yin
发明人： CHENG, Jun , LEE, Beng Hai , LIU, Jiang , AUNG, Tin , MANI, Baskaran , WONG, Tien Yin
IPC分类号： A61B5/00 , A61B8/10 , A61B3/00 , G06T7/60
CPC分类号： G06T7/0012 , G06T7/60 , G06T2207/20061 , G06T2207/30041
摘要： An eye image including an image of the region containing the intersection of the cornea and iris is processed to identify whether it contains two proximate lines, since it is experimentally observed that this is characteristic of a non-zero value of the iridocorneal angle. The method includes an edge detection step, and then a method of determining whether edges have been detected which comprise these two proximate lines. The lines may be required to meet pre-known criteria, which are obtained from knowledge about the structure of the eye. In this way, it is possible to reduce the influence of other spurious edges in the eye image. The invention makes possible a precise, efficient and automatic system to grade the angle, which in turn makes it possible to provide large-scale clinical use.
摘要翻译：处理包括包含角膜和虹膜交点的区域的图像的眼图，以识别其是否包含两个近似线，因为实验观察到这是虹膜角膜的非零值的特征。该方法包括边缘检测步骤，然后确定是否检测到包括这两个近似行的边缘的方法。可能需要线以满足从关于眼睛结构的知识获得的预先知道的标准。以这种方式，可以减少眼图中其他杂散边缘的影响。本发明使精确，有效和自动化的系统成为角度分级成为可能，从而使得可以提供大规模的临床应用。

4. 发明申请

WO2011059409A1 OBTAINING DATA FOR AUTOMATIC GLAUCOMA SCREENING, AND SCREENING AND DIAGNOSTIC TECHNIQUES AND SYSTEMS USING THE DATA 审中-公开
标题翻译：获取用于自动GLAUCOMA筛选的数据，以及使用数据的筛选和诊断技术和系统
公开(公告)号：WO2011059409A1
公开(公告)日：2011-05-19
申请号：PCT/SG2010/000434
申请日：2010-11-16
申请人： LIU, Jiang , ZHANG, Zhuo , WONG, Wing, Kee, Damon , TAN, Ngan, Meng , YIN, Fengshou , LEE, Beng Hai , LI, Huiqi , LIM, Joo, Hwee , CHEUNG, Carol , AUNG, Tin , WONG, Tien, Yin , LIANG, Ziyang , CHENG, Jun , MANI, Baskaran
发明人： LIU, Jiang , ZHANG, Zhuo , WONG, Wing, Kee, Damon , TAN, Ngan, Meng , YIN, Fengshou , LEE, Beng Hai , LI, Huiqi , LIM, Joo, Hwee , CHEUNG, Carol , AUNG, Tin , WONG, Tien, Yin , LIANG, Ziyang , CHENG, Jun , MANI, Baskaran
IPC分类号： A61B3/12
CPC分类号： A61B3/0025 , A61B3/12 , A61B5/02007 , A61B5/7264 , A61B5/7267 , A61B5/7275 , G06T7/0012 , G06T7/40 , G06T2207/30041
摘要： A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode. Texture analysis is performed on the fundus images to classify them based on their quality, and only images which are determined to meet a quality criterion are subjected to an analysis to determine if they exhibit glaucoma indicators. Also, the images are put into a standard format. The system may include estimating the position of the optic cup by combining results from multiple optic cup segmentation techniques. The system may include estimating the position of the optic disc by applying edge detection to the funds image, excluding edge points that are unlikely to be optic disc boundary points, and estimating the position of an optic disc by fitting an ellipse to the remaining edge points.
摘要翻译：使用非立体眼底图像来获得多个青光眼指示符。此外，用于受试者的基因组数据用于获得与与青光眼相关的一个或多个基因和/或SNP相关的遗传标记数据。青光眼指标和遗传标记数据被输入到适应模型中，该模型用于产生指示受试者青光眼风险的输出。综合来看，遗传指标和基因组数据对于青光眼的风险比孤立的两者之一更有信息。自适应模型可以是两阶段模型，其具有第一阶段，其中通过第一自适应模型模块将个体遗传指标与基因组数据的相应部分组合以形成相应的第一输出，第二阶段中，第一输出是通过第二自适应模式组合。对眼底图像进行纹理分析，根据其质量对其进行分类，仅对满足质量标准的图像进行分析，以确定其是否呈现青光眼指标。此外，图像被放入标准格式。该系统可以包括通过组合来自多个光学杯分割技术的结果来估计光学杯的位置。该系统可以包括通过对资金图像应用边缘检测来估计视盘的位置，不包括不太可能是视盘边界点的边缘点，以及通过将椭圆拟合到剩余边缘点来估计视盘的位置。

5. 发明申请

WO2009126116A1 SYSTEM AND METHOD FOR MONITORING WATER QUALITY 审中-公开
标题翻译：用于监测水质的系统和方法
公开(公告)号：WO2009126116A1
公开(公告)日：2009-10-15
申请号：PCT/SG2009/000133
申请日：2009-04-09
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , ENG, How Lung , LEE, Beng Hai , AGGRELLY, Suryanti Yunita , CHEW, Boon Fong
发明人： ENG, How Lung , LEE, Beng Hai , AGGRELLY, Suryanti Yunita , CHEW, Boon Fong
IPC分类号： G01N33/18
CPC分类号： C02F1/00 , C02F2209/00 , G01N33/186
摘要： A system and system for monitoring water quality. The system comprises a container for receiving a flow of water to be monitored, the container containing a plurality of fish and configured such that a substantially 3-dimensional group behaviour of the fish is accommodated; a first imaging device disposed above the container for obtaining top view video data of the fish; and means for identifying individual fish based on foreground object detection.
摘要翻译：一个用于监测水质的系统和系统。该系统包括用于接收待监测的水流的容器，容器包含多个鱼，并且构造成容纳鱼的基本上3维组的行为; 设置在所述容器上方的用于获得所述鱼的顶视图数据的第一成像装置; 以及用于基于前景物体检测识别个体鱼的装置。

6. 发明申请

WO2008008045A1 METHOD AND SYSTEM FOR CONTEXT-CONTROLLED BACKGROUND UPDATING 审中-公开
标题翻译：用于背景控制的背景更新的方法和系统
公开(公告)号：WO2008008045A1
公开(公告)日：2008-01-17
申请号：PCT/SG2007/000205
申请日：2007-07-11
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , LI, Liyuan , LUO, Ruijiang , MA, Ruihua , LEMAN, Karianto , KUMAR, Pankaj , LEE, Beng Hai , HUANG, Welmin
发明人： LI, Liyuan , LUO, Ruijiang , MA, Ruihua , LEMAN, Karianto , KUMAR, Pankaj , LEE, Beng Hai , HUANG, Welmin
IPC分类号： G06T7/20 , G06T5/40 , H04N7/18 , G06T1/00 , H04N5/225
CPC分类号： H04N7/18 , G06K9/00771 , G06K9/32 , G06K9/38 , G06K2009/3291 , G06T5/50 , G06T7/11 , G06T7/174 , G06T7/194 , G06T7/254 , G06T2207/10016 , G06T2207/20081
摘要： A method and system for background updating for adaptive background subtraction in a video signal. The method comprises the steps of defining one or more contextual background representation types; segmenting an image of a scene in the video signal into contextual background regions; classifying each contextual background region as belonging to one of the contextual background representation types; determining an orientation histogram representation (OHR), a principle colour representation (PCR), or both, of each background region; receiving a current image of the scene in the video signal; determining whether respective pixels in image regions of the current image spatially corresponding to the background regions are occluded or exposed; and setting different learning rates for the adaptive background subtraction for pixels that are occluded and for pixels that are exposed respectively.
摘要翻译：一种背景更新方法和系统，用于视频信号中的自适应背景减法。该方法包括定义一个或多个上下文背景表示类型的步骤; 将视频信号中的场景的图像分割为上下文背景区域; 将每个上下文背景区域分类为属于背景表示类型之一; 确定每个背景区域的方向直方图表示（OHR），原理颜色表示（PCR）或两者; 在视频信号中接收场景的当前图像; 确定在空间上对应于背景区域的当前图像的图像区域中的各个像素是否被遮挡或曝光; 并为被遮挡的像素和分别曝光的像素设置自适应背景减法的不同学习速率。

7. 发明申请

WO2012030304A1 A ROBOTIC DEVICE FOR USE IN IMAGE-GUIDED ROBOT ASSISTED SURGICAL TRAINING 审中-公开
标题翻译：用于图像引导机器人辅助手术训练的机器人装置
公开(公告)号：WO2012030304A1
公开(公告)日：2012-03-08
申请号：PCT/SG2011/000302
申请日：2011-09-01
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , NATIONAL UNIVERSITY HOSPITAL (S) PTE LTD , NATIONAL UNIVERSITY OF SINGAPORE , YANG, Tao , YANG, Liangjing , LIU, Jiang , CHUI, Chee Kong , HUANG, Weimin , ZHANG, Jing , ZHOU, Jiayin , LEE, Beng Hai , TAN, Ngan Meng , WONG, Wing Kee Damon , YIN, Fengshou , CHANG, Kin Yong , SU, Yi
发明人： YANG, Tao , YANG, Liangjing , LIU, Jiang , CHUI, Chee Kong , HUANG, Weimin , ZHANG, Jing , ZHOU, Jiayin , LEE, Beng Hai , TAN, Ngan Meng , WONG, Wing Kee Damon , YIN, Fengshou , CHANG, Kin Yong , SU, Yi
IPC分类号： G09B23/28 , B25J9/00 , B25J3/04 , B25J7/00 , A61B19/00 , G09B9/00
CPC分类号： G09B23/28 , A61B34/30 , B25J3/04 , B25J7/00 , G09B23/285
摘要： A robotic device for use in image-guided robot assisted surgical training, the robotic device comprising a manual interface structure configured to simulate handling of a surgical tool; a translational mechanism for translational motion of the manual interface structure; a rotational mechanism for rotational motion of the manual interface structure; and a spherical mechanism configured to decouple the orientation of the manual interface structure into spatial coordinates, wherein a linkage between the rotational mechanism, the rotational mechanism and the spherical mechanism, and the manual interface structure are disposed on opposing sides of an intersection of a pitch axis and a yaw axis of the spherical mechanism.
摘要翻译：一种用于图像引导机器人辅助外科手术训练的机器人装置，所述机器人装置包括被配置为模拟外科手术工具的处理的手动界面结构; 手动界面结构的平移运动的平移机制; 用于手动接口结构的旋转运动的旋转机构; 以及球面机构，被配置为将手动界面结构的取向分离成空间坐标，其中旋转机构，旋转机构和球面机构之间的联动以及手动界面结构设置在俯仰的交叉点的相对侧上轴和球面机构的偏转轴。

8. 发明申请

WO2011108994A1 ROBOT ASSISTED SURGICAL TRAINING 审中-公开
标题翻译：机器人辅助手术训练
公开(公告)号：WO2011108994A1
公开(公告)日：2011-09-09
申请号：PCT/SG2011/000087
申请日：2011-03-04
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , NATIONAL UNIVERSITY OF SINGAPORE , NATIONAL UNIVERSITY HOSPITAL (S) PTE LTD , HUANG, Weimin , LIU, Jiang , ZHOU, Jiayin , ZHANG, Jing , LEE, Beng Hai , WONG, Wing Kee, Damon , TAN, Ngan Meng , ZHANG, Zhou , YIN, Fengshou , CHANG, Stephen , CHUI, Chee Kong , SU, Yi
发明人： HUANG, Weimin , LIU, Jiang , ZHOU, Jiayin , ZHANG, Jing , LEE, Beng Hai , WONG, Wing Kee, Damon , TAN, Ngan Meng , ZHANG, Zhou , YIN, Fengshou , CHANG, Stephen , CHUI, Chee Kong , SU, Yi
IPC分类号： G09B9/00 , G09B23/28
CPC分类号： G09B23/28 , G06F19/00 , G09B23/30
摘要： A surgical training system and method. The system comprises means for recording reference data representing a reference manipulation of a computer generated model of an object by a master user; means for physically guiding a trainee user based on the recorded reference data during a training manipulation of the model of the object by the trainee user; and means for recording assessment data representing an assessment manipulation of the model of the object by the trainee user without guidance.
摘要翻译：外科手术训练系统及方法该系统包括用于记录表示由主用户计算机生成的对象的模型的参考操纵的参考数据的装置; 用于在由所述受训用户对所述对象的模型的训练操纵期间基于所记录的参考数据物理地引导所述受训用户的装置; 以及用于在没有指导的情况下记录代表对象的模型的评估操纵的评估数据的方法。

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