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1. 发明申请

WO2012055729A1 BOROPHOSPHATE PHOSPHOR AND LIGHT SOURCE 审中-公开
标题翻译：硼磷酸盐和光源
公开(公告)号：WO2012055729A1
公开(公告)日：2012-05-03
申请号：PCT/EP2011/068226
申请日：2011-10-19
申请人： LEUCHTSTOFFWERK BREITUNGEN GMBH , DUAN, Cheng-Jun , RÖSLER, Sven
发明人： DUAN, Cheng-Jun , RÖSLER, Sven
IPC分类号： C09K11/71
CPC分类号： C09K11/7737 , C09K11/774 , C09K11/7796 , C09K11/7797 , F21V9/30 , Y02B20/181
摘要： This invention is related to efficient inorganic borophosphate phosphors which can applied in various technical applications such as fluorescent lamps, colored light or white light emitting diodes, and other devices where phosphors are used to convert especially near UV radiation into the visible light. Further, this invention is related to light sources comprising the efficient borophosphate phosphor. The inventive phosphor absorbs radiation in a first wavelength range of the electromagnetic spectrum and emits radiation in a second wavelength range of the electromagnetic spectrum. This phospho is a borophosphate activated with divalent rare earth metal ions and is represented by the general formula: AX 1-x RE x BP 2 O 8 . Symbol A stand for at least one univalent alkaline metal ion. Symbol M represents at least one divalent metal ion. Symbol RE stands for at least one divalent ion selected from the group comprising rare earth metals Eu, Sm, and Yb as well as Pb, Sn, Cu, and Mn, wherein at least one of the divalent rare earth metal ions Eu, Sm, and/or Yb is acting as an activator. Variable x is limited by 0
摘要翻译：本发明涉及可用于诸如荧光灯，彩色光或白色发光二极管等各种技术应用的有效的无机磷光体磷光体，以及使用荧光体将UV辐射特别接近可见光的其它装置。此外，本发明涉及包含有效硼磷酸盐荧光体的光源。本发明的荧光体吸收电磁光谱的第一波长范围内的辐射并且在电磁光谱的第二波长范围内发射辐射。该磷酸是用二价稀土金属离子活化的硼磷酸盐，由通式AX1-xRExBP2O8表示。符号A代表至少一种一价碱金属离子。符号M表示至少一种二价金属离子。符号RE代表选自稀土金属Eu，Sm和Yb以及Pb，Sn，Cu和Mn中的至少一种二价离子，其中至少一种二价稀土金属离子Eu，Sm，和/或Yb作为活化剂。变量x受限于0

2. 发明申请

WO2011059409A1 OBTAINING DATA FOR AUTOMATIC GLAUCOMA SCREENING, AND SCREENING AND DIAGNOSTIC TECHNIQUES AND SYSTEMS USING THE DATA 审中-公开
标题翻译：获取用于自动GLAUCOMA筛选的数据，以及使用数据的筛选和诊断技术和系统
公开(公告)号：WO2011059409A1
公开(公告)日：2011-05-19
申请号：PCT/SG2010/000434
申请日：2010-11-16
申请人： LIU, Jiang , ZHANG, Zhuo , WONG, Wing, Kee, Damon , TAN, Ngan, Meng , YIN, Fengshou , LEE, Beng Hai , LI, Huiqi , LIM, Joo, Hwee , CHEUNG, Carol , AUNG, Tin , WONG, Tien, Yin , LIANG, Ziyang , CHENG, Jun , MANI, Baskaran
发明人： LIU, Jiang , ZHANG, Zhuo , WONG, Wing, Kee, Damon , TAN, Ngan, Meng , YIN, Fengshou , LEE, Beng Hai , LI, Huiqi , LIM, Joo, Hwee , CHEUNG, Carol , AUNG, Tin , WONG, Tien, Yin , LIANG, Ziyang , CHENG, Jun , MANI, Baskaran
IPC分类号： A61B3/12
CPC分类号： A61B3/0025 , A61B3/12 , A61B5/02007 , A61B5/7264 , A61B5/7267 , A61B5/7275 , G06T7/0012 , G06T7/40 , G06T2207/30041
摘要： A non-stereo fundus image is used to obtain a plurality of glaucoma indicators. Additionally, genome data for the subject is used to obtain genetic marker data relating to one or more genes and/or SNPs associated with glaucoma. The glaucoma indicators and genetic marker data are input into an adaptive model operative to generate an output indicative of a risk of glaucoma in the subject. In combination, the genetic indicators and genome data are more informative about the risk of glaucoma than either of the two in isolation. The adaptive model may be a two-stage model, having a first stage in which individual genetic indicators are combined with respective portions of the genome data by first adaptive model modules to form respective first outputs, and a second stage in which the first outputs are combined by a second adaptive mode. Texture analysis is performed on the fundus images to classify them based on their quality, and only images which are determined to meet a quality criterion are subjected to an analysis to determine if they exhibit glaucoma indicators. Also, the images are put into a standard format. The system may include estimating the position of the optic cup by combining results from multiple optic cup segmentation techniques. The system may include estimating the position of the optic disc by applying edge detection to the funds image, excluding edge points that are unlikely to be optic disc boundary points, and estimating the position of an optic disc by fitting an ellipse to the remaining edge points.
摘要翻译：使用非立体眼底图像来获得多个青光眼指示符。此外，用于受试者的基因组数据用于获得与与青光眼相关的一个或多个基因和/或SNP相关的遗传标记数据。青光眼指标和遗传标记数据被输入到适应模型中，该模型用于产生指示受试者青光眼风险的输出。综合来看，遗传指标和基因组数据对于青光眼的风险比孤立的两者之一更有信息。自适应模型可以是两阶段模型，其具有第一阶段，其中通过第一自适应模型模块将个体遗传指标与基因组数据的相应部分组合以形成相应的第一输出，第二阶段中，第一输出是通过第二自适应模式组合。对眼底图像进行纹理分析，根据其质量对其进行分类，仅对满足质量标准的图像进行分析，以确定其是否呈现青光眼指标。此外，图像被放入标准格式。该系统可以包括通过组合来自多个光学杯分割技术的结果来估计光学杯的位置。该系统可以包括通过对资金图像应用边缘检测来估计视盘的位置，不包括不太可能是视盘边界点的边缘点，以及通过将椭圆拟合到剩余边缘点来估计视盘的位置。

3. 发明申请

WO2008100344A3 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION 审中-公开
公开(公告)号：WO2008100344A3
公开(公告)日：2008-08-21
申请号：PCT/US2007/080734
申请日：2007-10-08
申请人： SIRIGEN INC. , GAYLORD, Brent, S. , HONG, Janice, W. , FU, Tsu-ju , SUN, Cheng, Jun
发明人： GAYLORD, Brent, S. , HONG, Janice, W. , FU, Tsu-ju , SUN, Cheng, Jun
IPC分类号： C12Q1/68
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.

4. 发明申请

WO2008100344A2 FLUORESCENT METHODS AND MATERIALS FOR DIRECTED BIOMARKER SIGNAL AMPLIFICATION 审中-公开
标题翻译：用于指导生物标志信号放大的荧光方法和材料
公开(公告)号：WO2008100344A2
公开(公告)日：2008-08-21
申请号：PCT/US2007/080734
申请日：2007-10-08
申请人： SIRIGEN INC. , GAYLORD, Brent, S. , HONG, Janice, W. , FU, Tsu-ju , SUN, Cheng, Jun
发明人： GAYLORD, Brent, S. , HONG, Janice, W. , FU, Tsu-ju , SUN, Cheng, Jun
IPC分类号： G01N33/53
CPC分类号： G01N33/582 , C08G61/02 , C08G61/12 , C08G61/128 , C08G2261/3142 , C08G2261/3221 , C08G2261/3241 , C08G2261/3246 , C08G2261/522 , C08G2261/78 , C08G2261/94 , G01N33/542 , H01L51/0039 , Y10T436/13
摘要： Methods and compositions are provided that include a multichromophore and/or multichromophore complex for identifying a target biomolecule. A sensor biomolecule, for example, an antibody can be covalently linked to the multichromophore. Additionally, a signaling chromophore can be covalently linked to the multichromophore. The arrangement is such that the signaling chromophore is capable of receiving energy from the multichromophore upon excitation of the multichromophore. Since the sensor biomolecule is capable of interacting with the target biomolecule, the multichromophore and/or multichromophore complex can provide enhanced detection signals for a target biomolecule.
摘要翻译：提供了包括用于鉴定目标生物分子的多色素和/或多色素复合物的方法和组合物。传感器生物分子，例如抗体可以共价连接到多色素。另外，信号发色团可以共价连接到多重色团。这种布置使得信号发色团能够在多重色素激发时能够从多重色淀中接收能量。由于传感器生物分子能够与目标生物分子相互作用，所以多重色谱和/或多重色谱复合物可以为目标生物分子提供增强的检测信号。

5. 发明申请

WO2007035140A1 METHOD AND TEST SIGNAL FOR MEASURING SPEECH INTELLIGIBILITY 审中-公开
标题翻译：用于测量语音智能的方法和测试信号
公开(公告)号：WO2007035140A1
公开(公告)日：2007-03-29
申请号：PCT/SE2005/001382
申请日：2005-09-20
申请人： TELEFONAKTIEBOLAGET LM ERICSSON (publ) , CHENG, Jun
发明人： CHENG, Jun
IPC分类号： H04B3/23 , G10L21/02 , H04B17/00
CPC分类号： H04B17/0085 , G10L25/69 , G10L2021/02082 , H04B3/234 , H04B17/0087 , H04B17/391 , H04M3/2236
摘要： The invention generally relates to measurement of speech intelligibility in a mobile communication network component handling two-way communication between two ends, typically a near-end and a far-end. A basic idea is to simulate (Sl) two-way speech communication based on test signals adapted for speech intelligibility measurements, detect double-talk (S2) during the simulated speech communication by using a double-talk detector, and perform (S3) speech intelligibility measurements only at periods of double-talk. In this way, it is for example possible to take the effects of echo into account in the speech intelligibility measurements, while avoiding undesirable effects from non-linear processing (and possible added comfort noise) in the signal path for which speech intelligibility is measured. Optionally, the operation of voice enhancement devices can be adjusted (S4) in response to the estimated speech intelligibility.
摘要翻译：本发明一般涉及在两端（通常是近端和远端）之间处理双向通信的移动通信网络组件中的语音可懂度的测量。一个基本思想是基于适用于语音清晰度测量的测试信号来模拟（S1）双向语音通信，通过使用双方通话检测器在模拟语音通信期间检测双向通话（S2），并执行（S3）语音清晰度测量仅在双方谈话的时候。以这种方式，例如可以在语音清晰度测量中考虑回声的影响，同时避免在测量语音清晰度的信号路径中的非线性处理（以及可能的附加的舒适噪声）的不期望的影响。可选地，可以响应于估计的语音清晰度来调整（S4）语音增强设备的操作。

6. 发明申请

WO2003054985A3 DISPOSABLE WORKING ELECTRODE FOR AN ELECTROCHEMICAL CELL 审中-公开
公开(公告)号：WO2003054985A3
公开(公告)日：2003-07-03
申请号：PCT/US2002/040281
申请日：2002-12-16
申请人： DIONEX CORPORATION , CHENG, Jun , JANDIK, Peter , AVDALOVIC, Nebojsa
发明人： CHENG, Jun , JANDIK, Peter , AVDALOVIC, Nebojsa
IPC分类号： G01N27/403
摘要： A flow-through electrochemical cell assembly with a disposable working electrode structure, including (a) a perimeter wall defining a sample flow channel including an inlet and an outlet, (b) a sample inlet line in fluid communication with the sample flow channel inlet, (c) a sample outlet line providing fluid communication between the sample flow channel outlet and a remote reference electrode, and (d) a disposable working electrode structure comprising an electrically conductive and electrochemically active working electrode region bound as a layer, directly or indirectly, to an electrically insulating substrate surface. The substrate surface is in fluid-sealing relationship with the sample flow channel, and the working electrode region is in fluid communication with said sample flow channel. The working electrode is vapor deposited, directly or indirectly, onto the organic polymer substrate through a mask, and a fluid seal is formed between said working electrode region and perimeter wall.

7. 发明申请

WO2011108995A1 AUTOMATIC ANALYSIS OF IMAGES OF THE ANTERIOR CHAMBER OF AN EYE 审中-公开
标题翻译：眼睛前庭的图像自动分析
公开(公告)号：WO2011108995A1
公开(公告)日：2011-09-09
申请号：PCT/SG2011/000088
申请日：2011-03-04
申请人： AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH , SINGAPORE HEALTH SERVICES PTE LTD , CHENG, Jun , LEE, Beng Hai , LIU, Jiang , AUNG, Tin , MANI, Baskaran , WONG, Tien Yin
发明人： CHENG, Jun , LEE, Beng Hai , LIU, Jiang , AUNG, Tin , MANI, Baskaran , WONG, Tien Yin
IPC分类号： A61B5/00 , A61B8/10 , A61B3/00 , G06T7/60
CPC分类号： G06T7/0012 , G06T7/60 , G06T2207/20061 , G06T2207/30041
摘要： An eye image including an image of the region containing the intersection of the cornea and iris is processed to identify whether it contains two proximate lines, since it is experimentally observed that this is characteristic of a non-zero value of the iridocorneal angle. The method includes an edge detection step, and then a method of determining whether edges have been detected which comprise these two proximate lines. The lines may be required to meet pre-known criteria, which are obtained from knowledge about the structure of the eye. In this way, it is possible to reduce the influence of other spurious edges in the eye image. The invention makes possible a precise, efficient and automatic system to grade the angle, which in turn makes it possible to provide large-scale clinical use.
摘要翻译：处理包括包含角膜和虹膜交点的区域的图像的眼图，以识别其是否包含两个近似线，因为实验观察到这是虹膜角膜的非零值的特征。该方法包括边缘检测步骤，然后确定是否检测到包括这两个近似行的边缘的方法。可能需要线以满足从关于眼睛结构的知识获得的预先知道的标准。以这种方式，可以减少眼图中其他杂散边缘的影响。本发明使精确，有效和自动化的系统成为角度分级成为可能，从而使得可以提供大规模的临床应用。

8. 发明申请

WO2011100248A1 ELECTROCHEMICAL DETECTION CELL FOR LIQUID CHROMATOGRAPHY SYSTEM 审中-公开
标题翻译：用于液相色谱系统的电化学检测细胞
公开(公告)号：WO2011100248A1
公开(公告)日：2011-08-18
申请号：PCT/US2011/024061
申请日：2011-02-08
申请人： DIONEX CORPORATION , CHENG, Jun , JANDIK, Petr , POHL, Christopher, A.
发明人： CHENG, Jun , JANDIK, Petr , POHL, Christopher, A.
IPC分类号： H01M14/00 , G01N27/26
CPC分类号： G01N27/30 , G01N27/301 , G01N27/4166 , G01N30/64
摘要： A detection cell for a chromatography system includes a cell body having an inlet, an outlet, and a counter electrode, a working electrode, a sample flow passageway extending between the inlet and the outlet and in fluid contact with the counter and working electrodes, and a palladium/noble metal reference electrode system. A method of using the detection cell is also described.
摘要翻译：用于色谱系统的检测电池包括具有入口，出口和对电极的电池体，工作电极，在入口和出口之间延伸并与计数器和工作电极流体接触的样品流动通道，以及钯/贵金属参考电极系统。还描述了使用检测单元的方法。

9. 发明申请

WO2009050171A2 RARE-EARTH DOPED ALKALINE-EARTH SILICON NITRIDE PHOSPHOR, METHOD FOR PRODUCING AND RADIATION CONVERTING DEVICE COMPRISING SUCH A PHOSPHOR 审中-公开
标题翻译：稀土掺杂的碱土氮化硅磷光体，生产和包含这种磷光体的辐射转换装置的方法
公开(公告)号：WO2009050171A2
公开(公告)日：2009-04-23
申请号：PCT/EP2008/063810
申请日：2008-10-14
申请人： LEUCHTSTOFFWERK BREITUNGEN GMBH , LEDON LIGHTING JENNERSDORF GMBH , DUAN, Cheng-Jun , HINTZEN, Hubertus Theresia , RÖSLER, Sylke , STARICK, Detlef , RÖSLER, Sven , DELSING, Anne Charlotte Anoinette
发明人： DUAN, Cheng-Jun , HINTZEN, Hubertus Theresia , RÖSLER, Sylke , STARICK, Detlef , RÖSLER, Sven , DELSING, Anne Charlotte Anoinette
IPC分类号： C09K11/08 , C09K11/79 , C09K11/80
CPC分类号： C09K11/0883 , C09K11/773 , C09K11/7734
摘要： The invention relates to a method of manufacturing a rare-earth doped alkaline-earth silicon nitride phosphor of a stoichiometric composition. Said method comprising the step of selecting one or more compounds each comprising at least one element of the group comprising the rare-earth elements (RE), the alkaline-earth elements (AE), silicon (Si) and nitrogen (N) and together comprising the necessary elements to form the rare-earth doped alkaline-earth silicon nitride phosphor (AE 2 Si 5 N 8 :RE). The method further comprises the step of bringing the compounds at an elevated temperature in reaction for forming the rare-earth doped alkaline-earth silicon nitride phosphor (AE 2 Si 5 N 8 :RE). In such a method normally a small amount of oxygen, whether intentionally or not-intentionally added, will be incorporated in the rare-earth doped alkaline-earth silicon nitride phosphor (AE 2 Si 5 N 8 :RE). According to the invention the creation of defects by formation of a non-stoichiometric oxygen containing phosphor is at least partly prevented by partly substituting for the ions (AE, Si, N) of the alkaline-earth silicon nitride phosphor (AE 2 Si 5 N 8 :RE) suitable further elements of the periodic system by which vacancies are created, filled or annihilated resulting in the formation of a modified alkaline-earth silicon nitride phosphor (AE 2 Si 5 N 8 :RE) having a stoichiometric composition. In this way a modified phosphor is obtained having excellent and stable optical properties. The invention further relates to a modified phosphor obtainable by the above-mentioned method and a radiation converting device comprising such a phosphor.
摘要翻译：本发明涉及制造化学计量组成的稀土掺杂碱土硅氮化物磷光体的方法。所述方法包括选择一种或多种化合物的步骤，所述化合物各自包含稀土元素（RE），碱土元素（AE），硅（Si）和氮（N）的组中的至少一种元素并且一起其包含形成稀土掺杂碱土硅氮化物磷光体（AE 2 N 5 N 8：RE）的必要元素。该方法还包括使化合物在升高的温度下反应以形成稀土掺杂的碱土硅氮化物磷光体（AE 2 Si 5 N 5）子> 8 ：RE）。在这种方法中，通常少量的氧，无论有意或无意添加，都将被掺入稀土掺杂的碱土硅氮化物磷光体（AE2Si5） /子>名词<子> 8 ：RE）。根据本发明，通过部分地替代碱土硅氮化物磷光体（AE 2，SiO 2）的离子（AE，Si，N）至少部分地防止通过形成非化学计量的含氧磷光体而产生缺陷低分子量元素：RE）是周期系统的合适的其他元素，通过该元素可以产生空穴，填充或消灭，导致形成修饰的碱 - 其具有化学计量组成的稀土氮化硅磷光体（AE 2 N 5 N 8：RE）。以这种方式获得具有优异且稳定的光学性质的改性磷光体。本发明还涉及可通过上述方法获得的改性荧光粉和包含这种荧光粉的辐射转换设备。

10. 发明申请

WO2007121267A3 PULSED ELECTROCHEMICAL DETECTION METHOD 审中-公开
公开(公告)号：WO2007121267A3
公开(公告)日：2007-10-25
申请号：PCT/US2007/066465
申请日：2007-04-11
申请人： DIONEX CORPORATION , CHENG, Jun , JANDIK, Petr , LIU, Xiaodong , POHL, Christopher, A.
发明人： CHENG, Jun , JANDIK, Petr , LIU, Xiaodong , POHL, Christopher, A.
IPC分类号： G01N27/403
摘要： In one embodiment, the present invention is directed to a pulsed electrochemical detection method comprising (a) flowing a liquid sample stream including at least one analyte past a working electrode in a flow-through cell; (b) applying at least three pulsed electrical potentials to the working electrode, (1) a first conditioning potential, (2) a second detection and oxidative cleaning potential, and (3) a third reductive cleaning potential, said second potential being higher than said first and third potentials and said first potential being higher than said third potential; and (c) detecting the output from said working electrode during the time period of applying said second potential.

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