专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2010142027A1 GUANINE RIBOSWITCH BINDING COMPOUNDS AND THEIR USE AS ANTIBIOTICS 审中-公开
标题翻译： GUANINE RIBOSWITCH BINDING化合物及其作为抗生素的用途
公开(公告)号：WO2010142027A1
公开(公告)日：2010-12-16
申请号：PCT/CA2010/000868
申请日：2010-06-14
申请人： SOCPRA - SCIENCES ET GENIE S. E. C. , MULHBACHER, Jérôme , LAFONTAINE , Daniel , MALOUIN , François , ALLARD , Marianne , MARSAULT , Eric
发明人： MULHBACHER, Jérôme , LAFONTAINE , Daniel , MALOUIN , François , ALLARD , Marianne , MARSAULT , Eric
IPC分类号： C07D239/46 , A61K31/513 , A61K31/519 , A61L2/16 , A61P31/04 , C07D239/48 , C07D239/50 , C07D239/56 , C07D498/04 , C07D513/04 , G01N33/569
CPC分类号： A61K31/675 , A61K31/4412 , A61K31/505 , A61K31/513 , A61K31/519 , A61K31/535 , A61K31/5383 , A61K31/54 , A61K31/542 , C07D239/46 , C07D239/48 , C07D239/50 , C07D498/04 , C07D513/04 , Y10T436/141111 , Y10T436/143333
摘要： The present invention includes novel compounds and pharmaceutically acceptable formulations of said compounds which exhibit antibiotic activity against microorganisms bearing a guanine riboswitch that controls the expression of the guaA gene, including organisms which are resistant to certain antibiotic families, and which are useful as antibacterial agents for treatment or prophylaxis of bacterial infections in animals or in humans, in particular but not limited to infections of the mammary gland, or their use as antiseptics, agents for sterilization or disinfection.
摘要翻译：本发明包括所述化合物的新化合物和药学上可接受的制剂，其对具有控制guaA基因表达的鸟嘌呤核糖开关的微生物具有抗生素活性，包括对某些抗生素家族具有抗性的生物体，并且其可用作抗细菌剂治疗或预防动物或人类的细菌感染，特别是但不限于乳腺感染，或其作为防腐剂的用途，用于灭菌或消毒的试剂。

2. 发明申请

WO2007067253A1 CARDIAC STIMULATION SYSTEM 审中-公开
标题翻译：心脏刺激系统
公开(公告)号：WO2007067253A1
公开(公告)日：2007-06-14
申请号：PCT/US2006/040291
申请日：2006-10-13
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
发明人： DRASLER, William J. , PIKUS, Michael J. , HASTINGS, Roger N. , SMITH, Scott R. , WILLARD, Martin R. , LAFONTAINE, Daniel M. , SAHOLT, Douglas R. , KVEEN, Graig L.
IPC分类号： A61N1/00 , A61B5/00
CPC分类号： A61N1/059 , A61B5/0031 , A61B5/042 , A61B5/6848 , A61B5/6882 , A61N1/0573 , A61N1/3684 , A61N1/37205 , A61N1/3756
摘要： Some embodiments of pacing systems employ wireless electrode assemblies to provide pacing therapy. The wireless electrode assemblies may wirelessly receive energy via an inductive coupling so as to provide electrical stimulation to the surrounding heart tissue. In certain embodiments, the wireless electrode assembly may include one or more biased tines that shift from a first position to a second position to secure the wireless electrode assembly into the inner wall of the heart chamber.
摘要翻译：起搏系统的一些实施例采用无线电极组件来提供起搏治疗。无线电极组件可以通过电感耦合无线地接收能量，以便向周围的心脏组织提供电刺激。在某些实施例中，无线电极组件可以包括从第一位置移动到第二位置的一个或多个偏置尖齿，以将无线电极组件固定到心室的内壁。

3. 发明申请

WO2004093694A1 PERCUTANEOUS TRANSLUMINAL ENDARTERECTOMY 审中-公开
标题翻译： PERCUTANEOUS TRANSLUMINAL ENDARTERECTOMOMY
公开(公告)号：WO2004093694A1
公开(公告)日：2004-11-04
申请号：PCT/US2004/005438
申请日：2004-02-24
申请人： SCIMED LIFE SYSTEMS, INC. , LAFONTAINE, Daniel, M.
发明人： LAFONTAINE, Daniel, M.
IPC分类号： A61B17/22
CPC分类号： A61B17/32037 , A61B17/22 , A61B17/22012 , A61B17/3207 , A61B17/320708 , A61B17/320725 , A61B2017/00243 , A61B2017/22042 , A61B2017/22094 , A61B2017/306 , A61B2017/320044 , A61B2017/320741 , A61B2090/0817 , A61B2090/3782 , A61F2/90
摘要： Methods and devices for performing intravascular endarterectomy. Methods includes intravascularly advancing a catheter having a carbon dioxide delivering distal end past a plaque-occluded vessel site, passing the distal end between the plaque and vessel wall. Other methods include intravascularly advancing paddles between plaque and vessel walls, including ultrasonic imaging paddles, ultrasonic vibrating paddles, and mechanically vibrating paddles. Some methods include providing intravascular devices having radially expandable jaws or paddles, and advancing those jaws or paddles along vessel walls to separate plaque from vessel walls. Still other methods include providing an anchoring guide catheter adapted to establish a suction grip around the left coronary artery ostium, and to use the anchored guide catheter to support intravascularly introduced endarterectomy devices operating on plaque in the left main coronary artery. One method utilizes retroperfusion of the coronary arteries to allow the anchoring guide catheter to remain in position for longer periods. Scissors-type expanding devices and stents for use after endarterectomy procedures are also provided.

4. 发明申请

WO2004091416A1 CRYOTREATMENT DEVICES AND METHODS OF FORMING CONDUCTION BLOCKS 审中-公开
标题翻译：造型装置和形成导电块的方法
公开(公告)号：WO2004091416A1
公开(公告)日：2004-10-28
申请号：PCT/US2004/010806
申请日：2004-04-08
申请人： SCIMED LIFE SYSTEMS, INC. , LAFONTAINE, Daniel, M.
发明人： LAFONTAINE, Daniel, M.
IPC分类号： A61B18/02
CPC分类号： A61B18/02 , A61B18/0218 , A61B2018/0212 , A61B2018/0262 , A61B2018/0293
摘要： Cryotreatment devices and methods of ablating tissue within the body are disclosed. A cryotreatment device in accordance with an exemplary embodiment of the present invention inlcudes an elongated member having one or more needle-like ablation tips configured to induce necrosis at a target site within the heart. A cooling fluid such as a cryogen may be injected through a lumen extending into the distal portion of the device. The ablation tips can be configured to pierce and ablate surrounding tissue, blocking electrical stimuli that can cause fibrillations or other arrhythmias of the heart. The device may also include means for controlling the transmural depth at which the ablation tips are inserted into the cardiac tissue. Methods of forming a contiguous line of conduction block in accordance with the present invention are also disclosed.
摘要翻译：公开了一种冷冻处理装置以及在体内消融组织的方法。根据本发明的示例性实施例的冷冻治疗装置包括具有一个或多个针状消融尖端的细长构件，其被配置为在心脏内的靶位点处诱导坏死。诸如冷冻剂的冷却流体可以通过延伸到装置的远端部分的内腔注入。消融尖端可以被配置为刺穿和消融周围的组织，阻止可引起心脏纤维化或其他心律失常的电刺激。该装置还可以包括用于控制消融尖端插入到心脏组织中的透壁深度的装置。还公开了形成根据本发明的连续导电阻挡线的方法。

5. 发明申请

WO2013138451A1 METHODS, SYSTEMS, AND DEVICES RELATING TO WIRELESS POWER TRANSFER 审中-公开
标题翻译：与无线电力传输相关的方法，系统和设备
公开(公告)号：WO2013138451A1
公开(公告)日：2013-09-19
申请号：PCT/US2013/030824
申请日：2013-03-13
申请人： SUNSHINE HEART COMPANY PTY LTD , LAFONTAINE, Daniel
发明人： LAFONTAINE, Daniel
IPC分类号： A61N1/05
CPC分类号： A61M1/127 , A61B2560/0219 , A61M1/12 , A61M1/122 , A61M2205/8243 , A61N1/3787 , H02J5/005 , H02J7/025 , H02J50/12 , H02J50/50
摘要： The various embodiments disclosed herein relate to transcutaneous energy transfer systems comprising an internal coil positioned within a cavity of a patient and an external coil inductively coupled to the internal coil. The systems can be coupled to any implantable medical devices, such as, for example, a heart assist device.
摘要翻译：本文公开的各种实施例涉及经皮能量传递系统，其包括位于患者空腔内的内部线圈和感应地联接到内部线圈的外部线圈。这些系统可以耦合到任何可植入医疗装置，例如心脏辅助装置。

6. 发明申请

WO2008073214A3 THERAPEUTIC CATHETER WITH DISPLACEMENT SENSING TRANSDUCER 审中-公开
公开(公告)号：WO2008073214A3
公开(公告)日：2008-06-19
申请号：PCT/US2007/024170
申请日：2007-11-16
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ESKURI, Alan , LAFONTAINE, Daniel
发明人： ESKURI, Alan , LAFONTAINE, Daniel
IPC分类号： A61M25/00 , A61B8/12
摘要： A catheter device having a proboscis, such as a needle (22), and a transducer which detects the axial displacement of the proboscis in relation to the distal tip or the catheter.. The transducer is positioned at a distal portion of the catheter and may comprise an induction coil (32) or a potentiometer. Axial displacement of the proboscis changes the amount of inductance or resistance in the transducer. This change in inductance or resistance can be calibrated to the amount of axial displacement of the proboscis and provided as feedback to the user.

7. 发明申请

WO2008034005A2 CARDIAC STIMULATION USING LEADLESS ELECTRODE ASSEMBLIES 审中-公开
标题翻译：使用无电极电极组件刺激心脏
公开(公告)号：WO2008034005A2
公开(公告)日：2008-03-20
申请号：PCT/US2007/078405
申请日：2007-09-13
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HASTINGS, Roger N. , LAFONTAINE, Daniel M. , PIKUS, Michael J. , WILLARD, Martin R.
发明人： HASTINGS, Roger N. , LAFONTAINE, Daniel M. , PIKUS, Michael J. , WILLARD, Martin R.
IPC分类号： A61N1/00
CPC分类号： A61N1/059 , A61N1/365 , A61N1/372 , A61N1/37205 , A61N1/37288 , A61N1/375 , A61N1/3756
摘要： An implantable cardiac tissue excitation system includes an implantable pacing controller unit with a pulse generation circuit. The system also includes a lead with a lead body extending between a proximal lead end attachable to the pacing controller unit and a distal lead end configured to be implanted within a heart. A lead conductor extends within the lead body. The system also includes a transmitter assembly located near the distal lead end that is electrically connected to the pulse generation circuit through the lead conductor to wirelessly transmit pacing control information and pacing energy. The system also includes a leadless electrode assembly configured to be implanted within the heart that includes a receiver to receive the wireless transmission, a charge storage unit to store the charge energy, and an electrical stimulation circuit to deliver an electrical stimulus to cardiac tissue using the pacing control information and the charge energy.
摘要翻译：可植入心脏组织激励系统包括具有脉冲发生电路的可植入起搏控制器单元。该系统还包括引线，引线主体在可附接到起搏控制器单元的近端引线端和配置成植入心脏内的远端引线端之间延伸。引线导体在引线体内延伸。该系统还包括位于远端引线端附近的发射器组件，该发射器组件通过引线导体电连接到脉冲发生电路以无线地发射起搏控制信息和起搏能量。该系统还包括被配置为植入心脏内的无引线电极组件，该无引线电极组件包括用于接收无线传输的接收器，用于存储电荷能量的电荷存储单元以及用于使用电信号向心脏组织递送电刺激的电刺激电路起搏控制信息和充电能量。

8. 发明申请

WO2007078770A3 ELECTRODE APPARATUS, SYSTEMS AND METHODS 审中-公开
标题翻译：电极装置，系统和方法
公开(公告)号：WO2007078770A3
公开(公告)日：2007-08-30
申请号：PCT/US2006047553
申请日：2006-12-14
申请人： BOSTON SCIENT SCIMED INC , KVEEN CRAIG L , HASTINGS ROGER N , SADASIVA ANUPAMA , SHAPOVALOV VITALY N , LAFONTAINE DANIEL M
发明人： KVEEN CRAIG L , HASTINGS ROGER N , SADASIVA ANUPAMA , SHAPOVALOV VITALY N , LAFONTAINE DANIEL M
IPC分类号： A61N1/378
CPC分类号： A61N1/056 , A61F2/88 , A61F2002/828 , A61F2250/0001 , A61N1/0565 , A61N1/057 , A61N1/37205 , A61N1/3787 , A61N2001/0585
摘要： Apparatus, system, and method that include a pacing apparatus having a stent electrode through which pulses of electrical current can be delivered. Stent electrodes receive energy for generating the electrical current from a variety of sources. Sources include from one or more induction coils that can form at least a portion of the stent. Sources can also include an implantable pulse generator coupled to a lead through which pulses of the electrical current are supplied to the stent electrodes.
摘要翻译：包括具有支架电极的起搏装置的装置，系统和方法，通过该支架电极可以输送电流脉冲。支架电极接收用于从各种来源产生电流的能量。来源包括可以形成支架的至少一部分的一个或多个感应线圈。源还可以包括耦合到引线的可植入脉冲发生器，电流的脉冲通过该引线被供应到支架电极。

9. 发明申请

WO2006083476A1 CATHETER WITH CUTTING HEADS 审中-公开
标题翻译：带切割头的导管
公开(公告)号：WO2006083476A1
公开(公告)日：2006-08-10
申请号：PCT/US2006/000280
申请日：2006-01-06
申请人： BOSTON SCIENTIFIC SCIMED, INC. , LAFONTAINE, Daniel, M. , JENSON, Mark, L. , DRASLER, William, J.
发明人： LAFONTAINE, Daniel, M. , JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61B17/22 , A61B17/32
CPC分类号： A61B17/32075 , A61B90/39 , A61B2017/00243 , A61B2017/22097 , A61F2/958
摘要： A catheter (100,200,300,500) including an elongate body (102,202,302,502) , a first cutting head (110,210,310,510) and a second cutting head (116,216,316,516) both having a blade (112, 212, 312, 512; 118, 218, 318, 518) , where the blades move relative each other to provide a shearing action for cardiac tissue. The catheter can further include a stent (238,338,538) positioned over an inflatable balloon (236,336,536) , where the inflatable balloon can deploy the expandable stent over sheared cardiac tissue. The catheter can further be included in a system having a sheath (446) , where at least a part of the catheter resides in the lumen (448) of the sheath. The sheath further includes a cardiac valve (454) and an expandable filter (470) . The sheath can move relative to the cardiac valve and the expandable filter to deploy the cardiac valve and at least a portion of the expandable filter proximal to the inflatable balloon and the expandable stent.
摘要翻译：包括细长主体（102,202,302,502），第一切割头（110,210,310,510）和第二切割头（116,216,316,516）的导管（100,200,300,500），其具有刀片（112,212,312,512; 118,218,318,518），其中叶片彼此相对移动以提供用于心脏组织的剪切动作。导管还可包括定位在可充气球囊（236,336,536）上方的支架（238,338,538），其中可充气球囊可以将可扩张的支架部署在剪切的心脏组织上。该导管可以进一步包括在具有护套（446）的系统中，其中导管的至少一部分位于护套的内腔（448）中。护套还包括心脏瓣膜（454）和可膨胀过滤器（470）。护套可以相对于心脏瓣膜和可膨胀过滤器移动，以将心脏瓣膜和可膨胀过滤器的至少一部分靠近可膨胀气囊和可扩张支架。

10. 发明申请

WO2006083472A1 FILTER SYSTEM WITH VALVE FOR USE IN VALVE REPLACEMENT AND METHOD OF MANUFACTURE 审中-公开
标题翻译：带阀门的过滤系统用于阀门更换和制造方法
公开(公告)号：WO2006083472A1
公开(公告)日：2006-08-10
申请号：PCT/US2006/000230
申请日：2006-01-06
申请人： BOSTON SCIENTIFIC SCIMED, INC. , LAFONTAINE, Daniel , JENSON, Mark, L. , DRASLER, William, J.
发明人： LAFONTAINE, Daniel , JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61F2/01
CPC分类号： A61F2/2418 , A61F2/01 , A61F2/013 , A61F2/2433 , A61F2/958 , A61F2002/011 , A61F2002/016 , A61F2002/018 , A61F2210/0019 , A61F2220/005 , A61F2220/0066 , A61F2230/0006 , A61F2230/0069 , A61F2230/008
摘要： A filter system (100), comprising an elongate filter body (102) defining a lumen and having a proximal end and a distal end. A valve (104) can be provided defining a lumen and having a reversibly sealable opening (116) for unidirectional flow of a fluid through the lumen. The valve can be adjoined proximal the distal end of the elongate filter body, wherein the elongate filter body filters the unidirectional flow of the fluid passing through the lumen of the valve and the lumen of the elongate filter body.
摘要翻译：一种过滤器系统（100），包括限定内腔并具有近端和远端的细长过滤体（102）。可以提供限定内腔的阀（104），并且具有可逆地密封的开口（116），用于流体通过内腔的单向流动。该阀可以在细长过滤体的远端附近邻近，其中细长的过滤器主体过滤通过阀的内腔和细长过滤体的内腔的单向流动。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式