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1. 发明申请

WO2010045240A3 SPECIAL PURPOSE FLUID DISPENSER 审中-公开
公开(公告)号：WO2010045240A3
公开(公告)日：2010-04-22
申请号：PCT/US2009/060516
申请日：2009-10-13
申请人： BIOQUIDDITY, INC. , KRIESEL, Marshall, S. , KRIESEL, Joshua, W. , THOMPSON, Thomas, N.
发明人： KRIESEL, Marshall, S. , KRIESEL, Joshua, W. , THOMPSON, Thomas, N.
IPC分类号： A61M5/14 , A61M5/168
摘要： A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible drug container that can be filled in the field with the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.

2. 发明申请

WO2007095356A2 DISTAL RATE CONTROL DEVICE 审中-公开
标题翻译：远程控制装置
公开(公告)号：WO2007095356A2
公开(公告)日：2007-08-23
申请号：PCT/US2007004120
申请日：2007-02-13
申请人： KRIESEL MARSHALL S , KRIESEL JOSHUA W , LANGERUD ALAN D , BIVIN DONALD B
发明人： KRIESEL MARSHALL S , KRIESEL JOSHUA W , LANGERUD ALAN D , BIVIN DONALD B
CPC分类号： A61M5/141 , A61M5/16804 , B01L3/502746 , F16K99/0001 , F16K99/0013 , F16K99/0028 , G05D7/0186 , Y10T137/7256 , Y10T137/7761 , Y10T137/8275
摘要： A distal rate control device, which can be conveniently interposed between a fluid supply line and fluid delivery line for precisely controlling the rate of fluid flow toward the delivery line. The device includes a readily adjustable flow rate control device having a novel flow control plate that can be placed in fluid communication with the fluid supply line and with the fluid delivery line. The flow control plate is provided with a plurality of elongated fluidic flow control channels that are in communication with a rate selector member that is rotatably carried by the device housing. Rotation of the rate selector member places a selected one of the flow control channels in communication with the fluid delivery line.
摘要翻译：远程速率控制装置，其可以方便地插入在流体供应管线和流体输送管线之间，用于精确地控制流向输送管线的流体流速。该装置包括易于调节的流量控制装置，其具有新颖的流量控制板，其可以被放置成与流体供应管线和流体输送管线流体连通。流量控制板设置有多个细长的流体流动控制通道，其与由装置壳体可旋转地承载的速率选择器构件连通。速率选择器构件的旋转将所选择的一个流量控制通道与流体输送管线连通。

3. 发明申请

WO1995028201A1 MIXING AND DELIVERY SYRINGE ASSEMBLY 审中-公开
标题翻译：混合输送装置组装
公开(公告)号：WO1995028201A1
公开(公告)日：1995-10-26
申请号：PCT/US1994004292
申请日：1994-04-18
申请人： SCIENCE INCORPORATED , KRIESEL, Marshall, S. , THOMPSON, Thomas, N.
发明人： SCIENCE INCORPORATED
IPC分类号： A61M37/00
CPC分类号： A61M5/2429 , A61M5/2448 , A61M5/348 , A61M2005/3104
摘要： This is a device for intermixing a first component, such as a parenteral fluid (27) with a second component, such as an immobilized drug carried by a scaffold (50) to form a beneficial agent which, following the mixture step, can be dispensed directly from the device for infusion into a patient. The device includes novel mechanisms for mateably interconnecting a container, such as a glass vial (30), containing the first component with a housing (12) having a fluid outlet (22) which houses a sealed container (44) containing the second component, and then for controllably mixing the components under sterile conditions to form an ingestable solution which is automatically dispensed through the fluid outlet of the device.
摘要翻译：这是用于将第一组分（例如肠胃外液体（27））与第二组分（例如由支架（50）携带的固定化药物）混合以形成有益剂的装置，其可以在混合步骤之后被分配直接从设备输注到患者身上。该装置包括用于将包含第一部件的容器（例如玻璃小瓶）的容器（30）可适配地互连的新颖机构，该容器具有容纳包含第二部件的密封容器（44）的流体出口（22）的壳体（12）然后用于在无菌条件下可控地混合组分以形成可通过装置的流体出口自动分配的可摄取溶液。

4. 发明申请

WO2010045239A2 SPECIAL PURPOSE FLUID DISPENSER WITH PRE-FILLED RESERVOIR 审中-公开
标题翻译：特殊用途液体分配器，带预充式储液器
公开(公告)号：WO2010045239A2
公开(公告)日：2010-04-22
申请号：PCT/US2009/060514
申请日：2009-10-13
申请人： BIOQUIDDITY, INC. , KRIESEL, Marshall, S. , KRIESEL, Joshua, W. , THOMPSON, Thomas, N.
发明人： KRIESEL, Marshall, S. , KRIESEL, Joshua, W. , THOMPSON, Thomas, N.
IPC分类号： A61M5/168 , A61M5/162
CPC分类号： A61M5/1454 , A61M5/141 , A61M5/148 , A61M5/16881 , A61M2005/1405 , A61M2005/14272 , A61M2202/048 , A61M2209/045
摘要： A compact, nonelectric fluid dispenser for use in controllably dispensing beneficial agents such as propofol and dexmedetomidine hydrochloride to patients. The dispenser includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient and embodies a collapsible, pre-filled drug container that contains the beneficial agents to be delivered to the patient. The unit-dose fluid dispenser of the invention is presented in a sterile and aseptic manner, where the drug has been pre-filled in the system, so that the practitioner cannot mistakenly give the wrong drug to the patient. The dispenser uniquely provides a more efficient medicament delivery system for procedure rooms, such as the endoscopy center, so that a greater number of patients can be treated per day at a higher standard of care with increased profits for the healthcare provider.
摘要翻译：用于可控地将有益物质如丙泊酚和右美托咪定盐酸盐分配给患者的紧凑非液体流体分配器。分配器包括流体流动控制组件，该流体流动控制组件精确地控制药物溶液向患者的流动并且体现包含待递送给患者的有益药剂的可折叠的，预填充的药物容器。本发明的单位剂量流体分配器以无菌和无菌的方式呈现，其中药物已经预填充在系统中，以便医师不会错误地将错误的药物给予患者。分配器独特地为诸如内窥镜检查中心等手术室提供更高效的药物输送系统，从而可以每天以更高的护理标准对更多患者进行治疗，从而为医疗保健提供者增加利润。

5. 发明申请

WO2007095297A3 FLUID DISPENSING APPARATUS WITH FLOW RATE CONTROL 审中-公开
标题翻译：流量分配装置与流量控制
公开(公告)号：WO2007095297A3
公开(公告)日：2008-10-09
申请号：PCT/US2007003934
申请日：2007-02-13
申请人： KRIESEL MARSHALL S , KRIESEL JOSHUA W , LANGERUD ALAN D
发明人： KRIESEL MARSHALL S , KRIESEL JOSHUA W , LANGERUD ALAN D
IPC分类号： A61M5/00
CPC分类号： A61M5/152 , A61M5/141 , A61M5/14244 , A61M5/16813 , A61M5/16881 , A61M5/24 , A61M5/2429 , A61M5/2466 , A61M5/3146 , A61M5/315 , A61M2005/1402 , A61M2005/3104 , A61M2005/3121 , A61M2005/3139
摘要： An apparatus for delivering fluids at precisely controlled rates to ambulatory patients. The invention comprises a housing having a fluid reservoir to contain fluids to be delivered to the patient, a novel stored energy membrane for expelling fluid from the reservoir and a unique flow control assembly in communication with the fluid reservoir for the precise infusion of pharmaceutical fluids to ambulatory patients at precisely controlled rates. The flow control assembly includes a novel rate control member having a plurality of fluidic micro-channels through which the fluid is selectively directed.
摘要翻译：用于以精确控制的速率向流动患者输送流体的装置。本发明包括具有流体储存器以容纳要输送到患者的流体的壳体，用于从储存器排出流体的新型存储的能量膜和与流体储存器连通以将药物流体精确地输送到门诊患者精确控制率。流量控制组件包括具有多个流体微通道的新型速率控制构件，流体被选择性地引导通过。

6. 发明申请

WO2005118053A3 FLUID DELIVERY DEVICE 审中-公开
标题翻译：流体输送装置
公开(公告)号：WO2005118053A3
公开(公告)日：2006-03-30
申请号：PCT/US2005018543
申请日：2005-05-25
申请人： KRIESEL MARSHALL S
发明人： KRIESEL MARSHALL S
IPC分类号： A61M5/14 , A61M5/142 , A61M5/145 , A61M5/148 , A61M5/24 , A61M37/00 , A61M5/152
CPC分类号： A61M5/148 , A61M5/141 , A61M5/14244 , A61M5/16877 , A61M5/2448 , A61M2005/14506 , A61M2205/7545 , A61M2209/045
摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, and like medicinal agents from prefilled containers at a uniform rate. The dispenser uniquely includes a stored energy source that is provided in the form of a compressible-expandable elastomeric member of novel construction that provides the force necessary to continuously aid uniformly expel fluid from the device reservoir. The device further includes a fluid flow control assembly that precisely controls the flow of the medicament solution to the patient.
摘要翻译：一种紧凑的流体分配器，用于以均匀的速率从预装容器中可控地分配流体药物，例如抗生素，溶瘤剂，激素，类固醇，凝血剂，止痛剂等药物。分配器独特地包括存储的能源，其以新颖结构的可压缩可膨胀弹性体构件的形式提供，其提供连续地辅助从装置储存器均匀排出流体所需的力。该装置还包括流体流动控制组件，其精确地控制药物溶液向患者的流动。

7. 发明申请

WO2005016408A3 MULTICHANNEL FLUID DELIVERY DEVICE 审中-公开
公开(公告)号：WO2005016408A3
公开(公告)日：2005-02-24
申请号：PCT/US2004/025255
申请日：2004-08-04
申请人： KRIESEL, Marshall, S. , LANGERUD, Alan
发明人： KRIESEL, Marshall, S. , LANGERUD, Alan
IPC分类号： A61M37/00
摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, and like medicinal agents from a plurality of prefilled containers at a uniform rate. The dispenser uniquely includes a plurality of stored energy source that are provided in the form of compressible-expandable members of novel construction that provide the force necessary to continuously and uniformly expel fluid from a plurality of device reservoirs. The apparatus further includes a plurality of fluid flow control assemblies that precisely control the flow of the medicament solutions from the plurality of device reservoirs to the patient.

8. 发明申请

WO2005016406A2 INFUSION APPARATUS WITH MODULATED FLOW CONTROL 审中-公开
标题翻译：具有调节流量控制的输液装置
公开(公告)号：WO2005016406A2
公开(公告)日：2005-02-24
申请号：PCT/US2004/025151
申请日：2004-08-04
申请人： KRIESEL, Marshall, S.
发明人： KRIESEL, Marshall, S.
IPC分类号： A61M
CPC分类号： A61M5/16877 , A61M5/1454
摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, oncolytics, hormones, steroids, blood clotting agents, analgesics, and like medicinal agents from prefilled containers at a uniform rate. The dispenser uniquely includes a stored energy source that is provided in the form of a substantially constant-force, compressible-expandable wave spring that provides the force necessary to continuously and uniformly expel fluid from the device reservoir. The device further includes a fluid flow control assembly that precisely controls the flow of medicament solution to the patient. Additionally, the device includes a novel modulating assembly for controllably modulating the force exerted by the wave spring tending to expel the fluid from the device reservoir.
摘要翻译：一种紧凑的流体分配器，用于以均匀的速率从预装容器中可控地分配流体药物，例如抗生素，溶瘤剂，激素，类固醇，凝血剂，止痛剂等药物。分配器独特地包括存储的能量源，其以基本上恒定的力可压缩的可膨胀的波形弹簧的形式提供，其提供连续且均匀地排出来自装置储存器的流体所需的力。该装置还包括流体流动控制组件，其精确地控制药物溶液流向患者的流动。另外，该装置包括一个新颖的调制组件，用于可控制地调制由波形弹力施加的力，以将流体从装置储存器排出。

9. 发明申请

WO1994025100A1 FLUID DISPENSER 审中-公开
标题翻译：流体分配器
公开(公告)号：WO1994025100A1
公开(公告)日：1994-11-10
申请号：PCT/US1994004392
申请日：1994-04-21
申请人： SCIENCE INCORPORATED , KRIESEL, Marshall, S.
发明人： SCIENCE INCORPORATED
IPC分类号： A61M37/00
CPC分类号： A61M5/152 , A61M5/1409
摘要： An elastomeric bladder type infusion device for delivering a beneficial agent, such as a drug to a patient at substantially a constant rate. The device uniquely includes an internally disposed functional substrate (46) which carries the beneficial agent so that it can be mixed with the fluid as the fluid is being introduced into the device to distent the bladder to make it an energy source for controllably dispensing the solution mixture to a patient.
摘要翻译：一种用于以基本恒定的速率将有益剂例如药物递送到患者的弹性体膀胱型输注装置。该装置独特地包括内部设置的功能性基底（46），其承载有益剂，使得当流体被引入装置中时可将其与流体混合以使囊膨胀以使其成为用于可控地分配溶液的能量源混合物给病人

10. 发明申请

WO2008112275A1 FLUID DISPENSING APPARATUS 审中-公开
标题翻译：流体分配装置
公开(公告)号：WO2008112275A1
公开(公告)日：2008-09-18
申请号：PCT/US2008/003328
申请日：2008-03-12
申请人： KRIESEL, Marshall, S. , KRIESEL, Joshua, W.
发明人： KRIESEL, Marshall, S. , KRIESEL, Joshua, W.
IPC分类号： A61M5/142
CPC分类号： A61M5/1454 , A61M5/148
摘要： A compact fluid dispenser for use in controllably dispensing fluid medicaments, such as antibiotics, blood clotting agents, analgesics, and like medicinal agents from collapsible containers at a uniform rate. The dispenser includes a novel stored energy source that is provided in the form of a compressible-expandable member that functions to continuously and uniformly expel fluid from the apparatus reservoir. The apparatus further includes a novel fluid flow control assembly that precisely controls the flow of the medicament solutions from the apparatus reservoir to the patient.
摘要翻译：一种紧凑型流体分配器，用于以可均匀速率从可收缩容器中可控地分配流体药物，例如抗生素，凝血剂，止痛剂等药物。分配器包括以可压缩可膨胀构件的形式提供的新型储存能量源，其用于连续且均匀地排出来自装置储存器的流体。该装置还包括新颖的流体流动控制组件，其精确地控制药物溶液从装置储存器到患者的流动。

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