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1. 发明申请

WO2008021541A2 CATHETER FOR CONDUCTING A PROCEDURE WITHIN A LUMEN, DUCT OR ORGAN OF A LIVING BEING 审中-公开
标题翻译：用于在一个生活中的一个人，一个或多个或者有机体内进行一个程序的导管
公开(公告)号：WO2008021541A2
公开(公告)日：2008-02-21
申请号：PCT/US2007/018366
申请日：2007-08-17
申请人： KENSEY NASH CORPORATION , FISHER, William, T. , YEAGER, David, E. , NASH, John, E.
发明人： FISHER, William, T. , YEAGER, David, E. , NASH, John, E.
IPC分类号： A61B17/22
CPC分类号： A61M25/0147 , A61B17/320758 , A61B2017/00367 , A61B2017/22038 , A61M25/005 , A61M25/0069 , A61M25/0082 , A61M25/0138 , A61M2025/0183
摘要： In an embodiment, the invention provides a catheter suitable for use in performing a procedure within a vessel, lumen or organ of a living having a distal end which is steerable, such as upon the application of compression. The catheter may be of the over the wire type, or alternatively may be a rapid exchange catheter. The catheter may provide for a rotating element which may be used to open a clogged vessel, or alternatively to provide information about adjacent tissues, such as may be generated by imaging or guiding arrangements using tissue detection systems known in the art, e.g., ultrasound, optical coherence reflectometry, etc. For rapid exchange catheters having a rotating element, there is provided an offset drive assembly to allow the rotary force to be directed from alongside the guidewire to a location coaxial to and over the guidewire.
摘要翻译：在一个实施方案中，本发明提供了一种适用于在具有可转向的远端（例如在施加压缩）的血管，内腔或器官内进行手术的导管。导管可以是导线类型，或者可以是快速交换导管。导管可以提供可用于打开堵塞的容器的旋转元件，或者替代地提供关于相邻组织的信息，例如可以通过使用本领域已知的组织检测系统的成像或引导装置来产生，例如超声波，光学相干反射测量法等。对于具有旋转元件的快速交换导管，设置有偏移驱动组件，以允许旋转力从导丝线旁边引导到与导线同轴并位于导线上方的位置。

2. 发明申请

WO2005082431A1 GEL SUITABLE FOR IMPLANTATION AND DELIVERY SYSTEM 审中-公开
标题翻译：凝胶适用于植入和输送系统
公开(公告)号：WO2005082431A1
公开(公告)日：2005-09-09
申请号：PCT/US2005/005621
申请日：2005-02-23
申请人： KENSEY NASH CORPORATION , RINGEISEN, Timothy A. , WATTENGEL, William Christian , BRADICA, Gino
发明人： RINGEISEN, Timothy A. , WATTENGEL, William Christian , BRADICA, Gino
IPC分类号： A61L27/24
CPC分类号： A61L27/56 , A61L27/20 , A61L27/24 , A61L27/52 , C08L5/08
摘要： The invention concerns a dried form of a porous polymer gel material which may be rehydrated and placed under pressure or compression to induce solvation, thereby forming a high concentration gel, in the form of an injectable viscous putty or dough, which may be implanted in the body.
摘要翻译：本发明涉及多孔聚合物凝胶材料的干燥形式，其可以被再水化并置于压力或压缩下以引发溶剂化，从而形成可注射粘性油灰或面团形式的高浓度凝胶，其可以植入身体。

3. 发明申请

WO2004037311A3 DEVICE AND METHODS FOR SEQUENTIAL, REGIONAL DELIVERY OF MULTIPLE CYTOTOXIC AGENTS 审中-公开
公开(公告)号：WO2004037311A3
公开(公告)日：2004-05-06
申请号：PCT/US2003/033669
申请日：2003-10-21
申请人： KENSEY NASH CORPORATION , BREKKE, John, H. , GUBBE, John, H.
发明人： BREKKE, John, H. , GUBBE, John, H.
IPC分类号： A61L31/04
摘要： An implantable delivery system includes a macrostructure formed of bioresorbable material selected from a group of alphahydroxy acids and defined to include an internal architecture of intercommunicating void spaces. A first cytotoxic agent in the preferred form of cisplatin is joined to the macrostructure during formation. A microstructure in the preferred form of a blend of high molecular weight hyaluronic acid conjugated with a second cytotoxic agent in the preferred form of paclitaxel and of pure high molecular weight hyaluronic acid is invested in the void spaces. Thus, when implanted, the paclitaxel and cisplatin are released sequentially, each initially at high level concentrations followed by lower release. Radiotherapy can be begun after the release of the paclitaxel has been completed but while the cisplatin is being released.

4. 发明申请

WO2004028592A1 PUMP DRIVE AND CONTROL SYSTEM FOR INFUSION TO AND ASPIRATION FROM A SURGICAL SITE 审中-公开
标题翻译：用于从外科手术室吸入和吸入的泵驱动和控制系统
公开(公告)号：WO2004028592A1
公开(公告)日：2004-04-08
申请号：PCT/US2003/029941
申请日：2003-09-23
申请人： KENSEY NASH CORPORATION
发明人： NASH, John E. , WALTERS, Gregory , HEIMAN, Stephen , BARNITZ, Jim , FATONE, Pete
IPC分类号： A61M1/00
CPC分类号： A61M1/0058 , A61M1/0035
摘要： A pumping system for use in medical applications where liquids must be infused and aspirated, and which is cost effective to simply dispose of it after a single use. The system features positive displacement pump(s) (64, 80) such as reciprocating pump(s) which may contain a damping mechanism to dampen out the peaks and valleys in the fluid pressure that is pumped, which is important for preventing cavitation. Embodiments furthermore feature a shut-off valve (76) on the extraction side so that certain injected fluids such as contrast medium, are not immediately pumped out of the patient. In a preferred embodiment, the system also features means for independently controlling the fluid pressure/volume on the infusion and extraction sides, self-priming capability, a continuous fluid path, and visual air bubble detection (20), with viewports located at important points in the fluid path, such as at pumps and valves.
摘要翻译：用于医疗用途的泵送系统，其中液体必须被输注和吸入，并且在单次使用之后简单处置它是成本有效的。该系统具有容积式泵（64,80），例如往复式泵，其可以包含阻尼机构，以阻止所泵送的流体压力中的峰和谷，这对于防止气蚀是重要的。实施例还具有在提取侧的截止阀（76），使得某些注射的流体（例如造影剂）不会被立即泵出患者体内。在优选实施例中，该系统还具有用于独立地控制输液和提取侧上的流体压力/体积，自吸能力，连续流体路径和视觉气泡检测（20）的装置，其中视口位于重要点在流体路径中，例如泵和阀。

5. 发明申请

WO2003039615A3 POROUS POLYMERIC PROSTHESES AND METHODS FOR MAKING SAME 审中-公开
公开(公告)号：WO2003039615A3
公开(公告)日：2003-05-15
申请号：PCT/US2002/035848
申请日：2002-11-07
申请人： KENSEY NASH CORPORATION , RINGEISEN, Timothy, A.
发明人： RINGEISEN, Timothy, A.
IPC分类号： A61L27/56
摘要： Porous polymers having a plurality of openings or chambers that are highly convoluted, with each chamber being defined by multiple, thin, flat partitions are produced by a new gel enhanced phase separation techinque. In a preferred embodiment, a second solven t is added to a ploymer solution, the second solvent causing the solution to gel. The gel can then be shaped as needed. Subsequent solvent extraction leaves the porous polymeric body of defined shape. The porous polymers have utility as medical protheses, t he porosity permitting ingrowth of neighboring tissue. The present technique also enhances shape-making capability, for example, of bifurcated vascular grafts, which feature a common entrance re gion but two or more exit regions.

6. 发明申请

WO2001068177A1 DEVICE FOR CONNECTING A CATHETER ONTO A GUIDE-WIRE 审中-公开
标题翻译：将导管连接到指导线的装置
公开(公告)号：WO2001068177A1
公开(公告)日：2001-09-20
申请号：PCT/US2001/007318
申请日：2001-03-08
申请人： KENSEY NASH CORPORATION , NASH, John, E. , FISHER, William, T. , CUNNINGHAM, H., Michael , WALTERS, Gregory
发明人： NASH, John, E. , FISHER, William, T. , CUNNINGHAM, H., Michael , WALTERS, Gregory
IPC分类号： A61M25/01
CPC分类号： A61M25/0169 , A61M25/00 , A61M25/0068 , A61M25/007 , A61M25/0074 , A61M25/09041 , A61M2025/0177 , A61M2025/018 , A61M2025/0186 , A61M2025/09008 , A61M2025/09125 , A61M2025/1056 , A61M2025/1095
摘要： A tubular instrument having a connector arranged to be used with a guide-wire extending into the body of a living being. The connector is located at the distal end of the instrument and is arranged to be readily manipulated by a twisting action to connect the instrument onto the guide-wire for sliding movement therealong.
摘要翻译：一种具有连接器的管状器具，其布置成与延伸进入生物体的导丝一起使用。连接器位于仪器的远端，并且被布置成容易地通过扭转动作来操纵，以将仪器连接到导丝上，以便在其上滑动。

7. 发明申请

WO1994005224A1 SURGICAL APPARATUS 审中-公开
标题翻译：外科手术
公开(公告)号：WO1994005224A1
公开(公告)日：1994-03-17
申请号：PCT/US1993008127
申请日：1993-08-27
申请人： KENSEY NASH CORPORATION , KENSEY, Kenneth , CLUPPER, Harold , NASH, John , MEIKLE, James, J., Jr. , DeWITT, Todd, M. , KEPHART, Herbert, G. , WALLS, James, A.
发明人： KENSEY NASH CORPORATION
IPC分类号： A61B17/34
CPC分类号： A61B17/29 , A61B17/282 , A61B17/2909 , A61B17/295 , A61B17/34 , A61B17/3417 , A61B2017/00353 , A61B2017/2944
摘要： Instruments (200A, 510, 610, 600A, 800A) for performing medical procedures in an interior portion, e.g., an insufflated abdomen (10), of the body of a living being from outside the body of the being via a small percutaneous incision or puncture (16, 514, 614, 2140). The instruments each include a distal portion having a working head in the form of a pair of jaws (210, 212, 530, 532, 630, 632, 230A, 232A, 610, 612, 610', 612', 610A, 612A), whose free end is sufficiently blunt as to not pose a danger to tissue within the abdomen. An extendable/retractable piercing device (300, 400, 620, 200C, 400A, 500A, 7000, 1000) which either forms a portion of the instrument or is separate therefrom is mounted on the distal end of the instrument and arranged to be extended to pierce through the skin to enable the working head to be passed through the skin and underlying tissue into the abdomen without the use of a trocar or other introducing device. A flange (408A, 4080, 1004) is provided in some embodiments to control the depth of penetration of the device. The instruments also include a proximal portion (202, 604A, 606A) arranged to be held outside the body of the being when the working head is located at the desired position. The piercing device is retractable from the instrument so that it doesn't pose a danger to internally located tissue. The instrument's jaws are opened or closed by manipulation of the proximal portion of the instrument to perform the procedure. After that is done the instrument is removed from the percutaneous incision or puncture, whereupon it seals itself.
摘要翻译：用于通过小的经皮切口从身体的外部进行生物体的内部例如吸入腹部（10）的医疗程序的仪器（200A，510,610,600A，800A）或穿刺（16,514,614,2140）。每个仪器包括具有一对钳口（210,212,530,532,630,632,230A，232A，610,612,610'，612'，610A，612A）形式的工作头部的远端部分，，其自由端足够钝，不会对腹部的组织造成危险。形成仪器的一部分或与其分离的可伸缩的穿刺装置（300,400,620,200C，400A，500A，7000,1000）安装在仪器的远端上，并被布置成延伸到穿透皮肤，使得工作头能够通过皮肤和下面的组织进入腹部，而不需要使用套管针或其他导入装置。在一些实施例中提供了凸缘（408A，4080,1004）以控制装置的穿透深度。仪器还包括一个近端部分（202,604A，606A），该近端部分（202,604A，606A）被布置成当工作头位于所需位置时被保持在身体的外部。刺穿装置可从仪器伸出，使其不会对内部定位的组织构成危险。通过操纵仪器的近端部分来打开或关闭仪器的钳口以执行该过程。之后，将仪器从经皮切开或穿刺中取出，从而将其自身密封。

8. 发明申请

WO1993007813A1 PLUG DEVICE FOR SEALING OPENINGS AND METHOD OF USE 审中-公开
标题翻译：用于密封开口的插头装置和使用方法
公开(公告)号：WO1993007813A1
公开(公告)日：1993-04-29
申请号：PCT/US1991007924
申请日：1991-10-25
申请人： KENSEY NASH CORPORATION
发明人： KENSEY NASH CORPORATION , KENSEY, Kenneth
IPC分类号： A61B17/04
CPC分类号： A61B17/0057 , A61B2017/00004 , A61F2/06
摘要： An instrument (22) and methods of making and use for sealing a small opening, e.g., percutaneous incisions or punctures (28). The instrument (22) includes a tubular member (30) having a proximal portion (34) and a distal portion (32) with an open free end (36) for introduction into the incision or puncture (28). A plug (20) comprises a cord (50) and a thin filament (52), with the cord (50) being formed of a resorbable material and being folded in two to form an apex portion (64) and a pair of wing portions (66A, 68A) extending therefrom. The plug (20) is located within the tubular member (30) so that the apex portion (64) is disposed adjacent the free end. The plug (20) is then expelled partially from the tubular member (30) so that the apex portion (64) extends through the incision or puncture (28). The filament (52) is then drawn proximally to pull the apex portion (64) into engagement with the free end of the tubular member to expand the apex portion to form a head (68) having a tissue engagement surface.
摘要翻译：仪器（22）以及用于密封例如经皮切口或穿刺（28）的小开口的方法。仪器（22）包括具有近端部分（34）和远侧部分（32）的管状构件（30），其具有用于引入切口或穿刺（28）的开放自由端（36）。插头（20）包括线（50）和细长丝（52），其中线（50）由可再吸收的材料形成并且被折叠成两个以形成顶点部分（64）和一对翼部（66A，68A）。插塞（20）位于管状构件（30）内，使得顶部部分（64）邻近自由端设置。塞子（20）然后部分地从管状构件（30）排出，使得顶点部分（64）延伸穿过切口或穿刺（28）。然后将细丝（52）向近侧拉伸以拉动顶点部分（64）与管状构件的自由端接合，以使顶部部分膨胀以形成具有组织接合表面的头部（68）。

9. 发明申请

WO2013123216A1 CENTRIFUGE 审中-公开
标题翻译：离心机
公开(公告)号：WO2013123216A1
公开(公告)日：2013-08-22
申请号：PCT/US2013/026175
申请日：2013-02-14
申请人： KENSEY NASH CORPORATION
发明人： NASH, John, E. , FISHER, William, T. , EVANS, Douglas, G.
IPC分类号： B04B1/02 , B04B5/04 , B04B7/08 , B04B11/04
CPC分类号： B04B11/04 , A61M1/3693 , A61M1/3696 , B01D21/262 , B01D21/34 , B01D2221/10 , B04B1/02 , B04B1/14 , B04B1/18 , B04B5/0407 , B04B5/0442 , B04B7/08 , B04B2005/0485
摘要： Centrifuges are useful to, among other things, remove red blood cells from whole blood and retain platelets and other factors in a reduced volume of plasma. Platelet rich plasma (PRP) and or platelet poor plasma (PPP) can be obtained rapidly and is ready for immediate injection into the host. Embodiments may include valves, operated manually or automatically, to open ports that discharge the excess red blood cells and the excess plasma into separate receivers while retaining the platelets and other factors in the centrifuge chamber. High speeds used allow simple and small embodiments to be used at the patients side during surgical procedures. The embodiments can also be used for the separation of liquids or slurries in other fields such as, for example, the separation of pigments or lubricants.
摘要翻译：除其他外，离心机可用于从全血中除去红细胞，并且在血浆体积减少中保留血小板和其他因子。血小板富集血浆（PRP）和或血小板不足血浆（PPP）可以快速获得并准备立即注射入宿主。实施例可以包括手动或自动地操作以打开将多余的红细胞和过量血浆排放到分离的接收器中的端口的阀，同时将血小板和其它因素保持在离心机室中。使用的高速度允许在外科手术期间在患者侧使用简单和小的实施例。这些实施方案也可用于在其它领域中分离液体或浆液，例如颜料或润滑剂的分离。

10. 发明申请

WO2006121474A1 SYSTEM AND DEVICES FOR THE REPAIR OF A VERTEBRAL DISC DEFECT 审中-公开
标题翻译：用于修复椎间盘缺损的系统和装置
公开(公告)号：WO2006121474A1
公开(公告)日：2006-11-16
申请号：PCT/US2006/004073
申请日：2006-02-06
申请人： KENSEY NASH CORPORATION
发明人： EVANS, Douglas G. , CAROUGE, Michael K. , BRADICA, Gino , KELLY, Jeffrey C. , OEFFINGER, Brian
IPC分类号： A61B17/70
CPC分类号： A61F2/4611 , A61B17/1604 , A61B17/1671 , A61B90/39 , A61B2090/061 , A61F2/442 , A61F2/4657 , A61F2002/30062 , A61F2002/30075 , A61F2002/3008 , A61F2002/3021 , A61F2002/30235 , A61F2002/30462 , A61F2002/30471 , A61F2002/30579 , A61F2002/30677 , A61F2002/30841 , A61F2002/4435 , A61F2002/444 , A61F2002/4495 , A61F2002/4627 , A61F2002/4662 , A61F2002/4685 , A61F2210/0004 , A61F2210/0061 , A61F2220/0075 , A61F2220/0091 , A61F2230/0067 , A61F2230/0069 , A61F2250/0098 , A61F2310/00011 , A61F2310/00365
摘要： A system for repairing a vertebral disc defect, such as hernia or bulge, a full or partial tear in the annulus, or a weakened annulus wall as a result of an excision procedure. The system introduces a treatment device arranged to repair the defect, and may prevent the leakage of fluid from the nucleus. The components of the device may be resorbable materials, and may induce the ingrowth of cellular material into the components. The system may feature a locating device to ensure proper placement of the treatment device.
摘要翻译：作为切除手术的结果，修复椎间盘缺损的系统，例如疝气或凸起，环形中的全部或部分撕裂或弱化的环空壁。该系统引入了一种处理装置，用于修复缺陷，并可防止流体从核中泄漏。装置的部件可以是可再吸收的材料，并且可以诱导细胞材料向组件中向内生长。该系统可以具有定位装置，以确保治疗装置的正确放置。

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