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1. 发明申请

WO2002034197A3 MICRO STORAGE, REACTION AND DETECTION CELLS AND METHODS AND APPARATUS FOR USE THEREOF 审中-公开
公开(公告)号：WO2002034197A3
公开(公告)日：2002-05-02
申请号：PCT/US2001/047265
申请日：2001-10-22
申请人： MICROBIOSCIENCES, INC. , JOBIN, Michael, J. , MUIR, Andrew, R. , SYKES, David, M. , WOODWARD, James, L.
发明人： JOBIN, Michael, J. , MUIR, Andrew, R. , SYKES, David, M. , WOODWARD, James, L.
IPC分类号： G01N30/02
摘要： Disclosed are devices and methods for the storage, shipment, moving and/or transferring, mixing, reacting, isolation, conditioning, lyophilization, stabilization, metering, dispensing, detecting, manipulation and management of materials, particularly solids, powders and liquids. Each such device or method provides a means of storing one or more quantities of one or more materials in one or more reservoirs, optionally protecting said quantities from air, moisture or light. Optionally, multiple such reservoirs may be placed or arranged in ensembles such as in arrays or other physical patterns, optionally providing for the simultaneous, parallel or rapid access to more than one such reservoir at once. Devices and methods of the invention may also be configured to deliver material from a reservoir in such manner that a defined or desired quantity of material is dispensed from the reservoir or that such dispensing is performed at a defined or desired rate or that the material is dispensed until one or more criteria are met for such dispensing to cease.

2. 发明申请

WO0234197A2 MICRO STORAGE, REACTION AND DETECTION CELLS AND METHODS AND APPARATUS FOR USE THEREOF 审中-公开
标题翻译：微存储，反应和检测细胞及其使用方法和装置
公开(公告)号：WO0234197A2
公开(公告)日：2002-05-02
申请号：PCT/US0147265
申请日：2001-10-22
申请人： MICROBIOSCIENCES INC , JOBIN MICHAEL J , MUIR ANDREW R , SYKES DAVID M , WOODWARD JAMES L
发明人： JOBIN MICHAEL J , MUIR ANDREW R , SYKES DAVID M , WOODWARD JAMES L
IPC分类号： B01L3/00 , B01L99/00 , B81B1/00 , C40B60/14 , A61J
CPC分类号： B01L3/5025 , B01J2219/00315 , B01J2219/00317 , B01L3/0293 , B01L3/50255 , B81B1/00 , C40B60/14
摘要： Disclosed are devices and methods for the storage, shipment, moving and/or transferring, mixing, reacting, isolation, conditioning, lyophilization, stabilization, metering, dispensing, detecting, manipulation and management of materials, particularly solids, powders and liquids. Each such device or method provides a means of storing one or more quantities of one or more materials in one or more reservoirs, optionally protecting said quantities from air, moisture or light. Optionally, multiple such reservoirs may be placed or arranged in ensembles such as in arrays or other physical patterns, optionally providing for the simultaneous, parallel or rapid access to more than one such reservoir at once. Devices and methods of the invention may also be configured to deliver material from a reservoir in such manner that a defined or desired quantity of material is dispensed from the reservoir or that such dispensing is performed at a defined or desired rate or that the material is dispensed until one or more criteria are met for such dispensing to cease.
摘要翻译：公开了用于材料特别是固体，粉末和液体的储存，运输，移动和/或转移，混合，反应，隔离，调节，冻干，稳定化，计量，分配，检测，操纵和管理的装置和方法。每个这样的装置或方法提供了一种或多种量的一种或多种材料存储在一个或多个储存器中的手段，可选地保护所述量不受空气，潮湿或光线的影响。可选地，可以将多个这样的储存器放置或布置在诸如阵列或其它物理模式的组合中，可选地提供一次同时，平行或快速访问多于一个这样的储存器。本发明的装置和方法也可以被构造成以这样的方式从储存器输送材料，即从储存器分配限定的或期望的量的材料或者以限定的或期望的速率执行这种分配或者分配材料直到满足一个或多个标准才能停止这种分配。

3. 发明申请

WO2010078428A1 OPHTHALMIC FLUID DELIVERY SYSTEM 审中-公开
标题翻译： OPHTHALMIC流体输送系统
公开(公告)号：WO2010078428A1
公开(公告)日：2010-07-08
申请号：PCT/US2009/069822
申请日：2009-12-30
申请人： OPTIMYST SYSTEMS, INC. , COLLINS, James, F., Jr. , JOBIN, Michael, J.
发明人： COLLINS, James, F., Jr. , JOBIN, Michael, J.
IPC分类号： A62C13/62
CPC分类号： A61M11/005 , A61B17/20 , A61F9/0008 , A61M11/042 , A61M11/065 , A61M2205/3372 , A61M2205/3386 , A61M2205/3653 , A61M2205/368 , A61M2205/50 , A61M2205/581 , A61M2205/583 , A61M2205/8206 , A61M2210/0612 , B05B17/0623 , B05B17/063 , B05B17/0646
摘要： An ophthalmic fluid atomizer including a body having a proximal end and a distal end and a container connected to the body, wherein the container contains an ophthalmic fluid disposed therein. The atomizer further including a discharge plate disposed at the distal end and a wick extending from the container to the discharge plate and transmitting the ophthalmic fluid from the container to the discharge plate via capillary action. Transmission of the ophthalmic fluid across the discharge plate generates a plume of ophthalmic fluid along a direction directly toward the eye. wherein the plume of ophthalmic fluid travels unassisted from the discharge plate to the eye and at the eye has a momentum subliminal to at least one of an ocular blink reflex and a lacrimation reflex of the eye.
摘要翻译：一种眼科液雾化器，其包括具有近端和远端的主体和连接到所述主体的容器，其中所述容器包含设置在其中的眼科液体。雾化器还包括设置在远端处的排放板和从容器延伸到排出板的芯，并且通过毛细作用将眼液从容器传输到排出板。穿过排放板的眼液的透射沿着直接朝向眼睛的方向产生羽流的眼液。其中所述眼科液体羽流从所述排出板向所述眼睛行进，并且在所述眼睛处具有向眼睛的眼睛眨眼反射和流淌反射中的至少一种的动量。

4. 发明申请

WO0234197A9 MICRO STORAGE, REACTION AND DETECTION CELLS AND METHODS AND APPARATUS FOR USE THEREOF 审中-公开
标题翻译：微存储，反应和检测细胞及其使用的方法和装置
公开(公告)号：WO0234197A9
公开(公告)日：2002-09-12
申请号：PCT/US0147265
申请日：2001-10-22
申请人： MICROBIOSCIENCES INC , JOBIN MICHAEL J , MUIR ANDREW R , SYKES DAVID M , WOODWARD JAMES L
发明人： JOBIN MICHAEL J , MUIR ANDREW R , SYKES DAVID M , WOODWARD JAMES L
IPC分类号： B01L3/00 , B01L99/00 , B81B1/00 , C40B60/14 , G01N30/02 , B01L9/00 , B01L11/00
CPC分类号： B01L3/5025 , B01J2219/00315 , B01J2219/00317 , B01L3/0293 , B01L3/50255 , B81B1/00 , C40B60/14
摘要： Disclosed are devices and methods for the storage, shipment, moving and/or transferring, mixing, reacting, isolation, conditioning, lyophilization, stabilization, metering, dispensing, detecting, manipulation and management of materials, particularly solids, powders and liquids. Each such device or method provides a means of storing one or more quantities of one or more materials in one or more reservoirs, optionally protecting said quantities from air, moisture or light. Optionally, multiple such reservoirs may be placed or arranged in ensembles such as in arrays or other physical patterns, optionally providing for the simultaneous, parallel or rapid access to more than one such reservoir at once. Devices and methods of the invention may also be configured to deliver material from a reservoir in such manner that a defined or desired quantity of material is dispensed from the reservoir or that such dispensing is performed at a defined or desired rate or that the material is dispensed until one or more criteria are met for such dispensing to cease.
摘要翻译：公开了用于储存，运输，移动和/或转移，混合，反应，隔离，调节，冻干，稳定，计量，分配，检测，操作和管理材料，特别是固体，粉末和液体的装置和方法。每个这样的装置或方法提供了将一种或多种量的一种或多种材料存储在一个或多个储存器中的方法，可任选地保护所述量免受空气，水分或光的影响。可选地，多个这样的储存器可以放置或排列成诸如阵列或其它物理图案的组合，任选地同时提供同时，平行或快速地进入多于一个这样的储存器。本发明的装置和方法还可以被配置成以这样的方式从储存器输送材料，即从容器中分配限定的或期望量的材料，或者以限定的或期望的速度进行这种分配，或者材料被分配直到满足这种分配的一个或多个标准才能停止。

5. 发明申请

WO0164345A3 MICROVOLUME LIQUID DISPENSING 审中-公开
标题翻译： MICROVOLUME液体分配
公开(公告)号：WO0164345A3
公开(公告)日：2002-01-31
申请号：PCT/US0106174
申请日：2001-02-27
申请人： BOSTON INNOVATION INC , KARG JEFFREY A , KRONCKE DOUGLAS W , JOBIN MICHAEL J
发明人： KARG JEFFREY A , KRONCKE DOUGLAS W , JOBIN MICHAEL J
IPC分类号： B01J19/00 , B01L3/02 , B01L99/00 , C40B60/14 , G01N35/10 , B01L11/00
CPC分类号： G01N35/1074 , B01J19/0046 , B01J2219/00315 , B01J2219/00317 , B01J2219/00353 , B01J2219/00364 , B01L3/0265 , B01L3/0293 , B01L2200/0605 , C40B60/14 , G01N35/1002
摘要： A sealed reservoir (21) for integrated packaging, shipping, storage and precise dispensing of extremely small volumes of liquids includes an integrated metering tap. The tap has a metering tube (25), which is translatable between a fill position inside the reservoir and an expel position outside the reservoir. The metering tube (25) includes a tube end closure (31) in a lower portion of the tube, a port (32) above the tube end closure, and a piston (29) in an upper portion of the tube. The piston (29) is movable between a down position that seals the side port (32) and an up position above the port (32). Movement of the piston (29) from the up position to the down position can displace from 10 nanoliters to 20 microliters. Several such dispensers are arranged in an integrated array of reservoir/tap units (20) suitable for use in automated, multi-well formats such as those commonly used for high-throughput screening.
摘要翻译：用于集成包装，运输，储存和精确分配极小体积液体的密封储存器（21）包括集成的计量抽头。水龙头具有计量管（25），其可在储存器内的填充位置与储存器外的排出位置之间平移。计量管（25）包括在管的下部的管端封闭件（31），管端封闭件上方的端口（32）和管件上部的活塞（29）。活塞（29）可在密封侧端口（32）的下降位置和端口（32）上方的上方位置之间移动。活塞（29）从上升位置向下位置的运动可以从10纳升到20微升。几个这样的分配器被布置在适合用于自动化，多孔格式（例如通常用于高通量筛选的那些）的储存器/分接头单元（20）的集成阵列中。

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