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1. 发明申请

WO2010017299A2 A UNIVERSAL TESTING PLATFORM FOR MEDICAL DIAGNOSTICS AND AN APPARATUS FOR READING TESTING PLATFORMS 审中-公开
标题翻译：医学诊断通用测试平台和阅读测试平台的设备
公开(公告)号：WO2010017299A2
公开(公告)日：2010-02-11
申请号：PCT/US2009/052857
申请日：2009-08-05
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , PIASIO, Roger, N. , WHEELER, Andrew , TURMEL, Christopher , GEVA, Ziv , LEIZEROVICH, Ofer
发明人： PIASIO, Roger, N. , WHEELER, Andrew , TURMEL, Christopher , GEVA, Ziv , LEIZEROVICH, Ofer
IPC分类号： A61B5/00 , A61B10/00 , B01L3/00
CPC分类号： A61B10/0051 , A61B5/0059 , A61B5/415 , A61B2562/08 , A61B2562/085 , B01F13/0059 , B01F13/0818 , B01L3/5023 , B01L3/5029 , B01L2200/143 , B01L2300/021 , B01L2300/024 , B01L2300/027 , B01L2300/0681 , B01L2300/0825 , B01L2300/126 , B01L2400/0409 , B01L2400/0644 , B01L2400/065 , G01N21/8483
摘要： A method and an apparatus for optically reading test devices having an identification data zone associated with the test device and test zone arranged to receive a sample. The apparatus comprises an optical sensing module, an image processing module coupled to the optical sensing module, a control module coupled to the optical sensing module and to the image-processing module. The optical sensing module is arranged to sense both the test zone and the identification data zone and deliver the sensed data to the image processing module responsive to the control module. Further, the image-processing unit is arranged to perform image processing on the sensed data from the test zone and from the identification data zone and further determine the sample according to the sensed data from the test zone in view of the sensed data from the identification data zone responsive to the control unit.
摘要翻译：一种用于光学读取具有与测试装置相关联的识别数据区域和被设置为接收样本的测试区域的测试装置的方法和装置。该装置包括光学感测模块，耦合到光学感测模块的图像处理模块，耦合到光学感测模块和图像处理模块的控制模块。光学感测模块被布置成感测测试区域和识别数据区域，并且响应于控制模块将感测到的数据传送到图像处理模块。此外，图像处理单元被布置为对来自测试区域和识别数据区域的感测数据执行图像处理，并且根据来自识别的感测数据，根据来自测试区域的感测数据进一步确定样本响应于控制单元的数据区。

2. 发明申请

WO2009147437A1 ASSAY READER, DEVICE AND METHOD FOR MEASURING HCG 审中-公开
标题翻译：测定读数器，测量HCG的装置和方法
公开(公告)号：WO2009147437A1
公开(公告)日：2009-12-10
申请号：PCT/GB2009/050619
申请日：2009-06-03
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , ELLIS, Jayne , MARSHALL, Jayne
发明人： ELLIS, Jayne , MARSHALL, Jayne
IPC分类号： G01N33/68 , G01N33/543
CPC分类号： G01N33/689 , G01N21/8483 , G01N33/54386 , G01N33/558 , G01N33/76 , G01N2021/8488 , G01N2333/59
摘要： Disclosed is a method for determining a quantitative estimate of the length of time since conception in a female mammalian subject, the method comprising: a)providing a liquid sample suspected of containing hCG; b)measuring, by means of an assay or assay device, an analyte measurement signal, whose value is dependent upon the level of hCG; c)comparing the measured signal value to an analyte threshold, wherein said analyte threshold corresponds to a time since conception; d)providing an quantitative estimate of the length of time since conception based upon the comparison in step (c).
摘要翻译：公开了一种用于确定雌性哺乳动物受试者自受孕以来的时间长度的定量估计的方法，所述方法包括：a）提供疑似含有hCG的液体样品; b）通过测定或测定装置测量其值取决于hCG水平的分析物测量信号; c）将测量的信号值与分析物阈值进行比较，其中所述分析物阈值对应于受孕后的时间; d）基于步骤（c）中的比较，提供自受孕以来时间长度的定量估计。

3. 发明申请

WO2009082781A1 ASSAY METHOD 审中-公开
标题翻译：测定方法
公开(公告)号：WO2009082781A1
公开(公告)日：2009-07-09
申请号：PCT/AU2008/001919
申请日：2008-12-24
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , HUANG, Chang-Yi , DE LAS HERAS, Rachel , FRY, Scott, Robert , LI, Jun
发明人： HUANG, Chang-Yi , DE LAS HERAS, Rachel , FRY, Scott, Robert , LI, Jun
IPC分类号： C12Q1/66 , G01N33/53
CPC分类号： C12Q1/66 , G01N33/581
摘要： A method is described for determining the presence of an analyte of interest in a sample which, method comprises contacting the sample with: (i) a purified first reporter fragment pair member comprising an interactor domain with affinity for the analyte of interest; and (ii) a purified second reporter fragment pair member comprising an interactor domain with affinity for the analyte of interest and operable in reconstituting an active enzyme upon association with the first reporter fragment pair member through the affinities of the interactor domains of the first and second reporter fragment pair members with the analyte of interest; under in vitro assay conditions which allow the first and second reporter fragment pair members to associate in the presence of analyte of interest in the sample through the affinity of the interactor domains with the analyte to produce a glow luminescent signal through the action of the reconstituted active enzyme on a substrate; and detecting the presence or absence, or extent, of a glow luminescent signal.
摘要翻译：描述了一种用于确定样品中感兴趣分析物的存在的方法，所述方法包括使样品与以下物质接触：（i）包含对感兴趣的分析物具有亲和力的相互作用结构域的纯化的第一报道片段对成员; 和（ii）纯化的第二报道片段对成员，其包含对目标分析物具有亲和力的相互作用结构域，并且可通过第一和第二相互作用结构域的亲和力与第一报告片段对成员缔合而重新构建活性酶记录片段对成员与感兴趣的分析物; 在体外测定条件下，其允许第一和第二报告物片段对成员通过相互作用域与分析物的亲和性在样品中的目标分析物存在下结合，以通过重构活性物质的作用产生发光发光信号酶在基质上; 并检测发光发光信号的存在或不存在。

4. 发明申请

WO2008135862A3 DEVICES AND METHODS FOR DETECTING ANALYTES 审中-公开
标题翻译：检测分析物的装置和方法
公开(公告)号：WO2008135862A3
公开(公告)日：2008-12-31
申请号：PCT/IB2008001677
申请日：2008-03-17
申请人： INVERNESS MEDICAL SWITZERLAND , WU XIN , ZHAO FUQUAN , WU YINFEI , GAO FEI
发明人： WU XIN , ZHAO FUQUAN , WU YINFEI , GAO FEI
IPC分类号： G01N33/543 , G01N33/52 , G01N33/558
CPC分类号： G01N33/558
摘要： This invention provides devices and methods for detecting an analyte suspected to be present in a sample. The subject devices and methods are particularly useful for performing immunoassays on a variety of analyte, especially those present in a bodily fluid.
摘要翻译：本发明提供了用于检测怀疑存在于样品中的分析物的装置和方法。本发明的装置和方法对于对各种分析物，尤其是存在于体液中的分析物进行免疫分析特别有用。

5. 发明申请

WO2008135862A2 DEVICES AND METHODS FOR DETECTING ANALYTES 审中-公开
标题翻译：用于检测分析仪的装置和方法
公开(公告)号：WO2008135862A2
公开(公告)日：2008-11-13
申请号：PCT/IB2008/001677
申请日：2008-03-17
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , WU, Xin , ZHAO, Fuquan , WU, Yinfei , GAO, Fei
发明人： WU, Xin , ZHAO, Fuquan , WU, Yinfei , GAO, Fei
IPC分类号： G01N33/543 , G01N33/558 , G01N33/52
CPC分类号： G01N33/558
摘要： This invention provides devices and methods for detecting an analyte suspected to be present in a sample. The subject devices and methods are particularly useful for performing immunoassays on a variety of analyte, especially those present in a bodily fluid.
摘要翻译：本发明提供用于检测疑似存在于样品中的分析物的装置和方法。本发明的装置和方法对于对各种分析物，特别是存在于体液中的分析物进行免疫测定特别有用。

6. 发明申请

WO2008075193A2 ASSAY DEVICES AND METHODS 审中-公开
标题翻译：测定装置和方法
公开(公告)号：WO2008075193A2
公开(公告)日：2008-06-26
申请号：PCT/IB2007/004021
申请日：2007-12-19
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , SKELLY, Peter John , BALBIR, Raj , KASIDAS, Nadine
发明人： SKELLY, Peter John , BALBIR, Raj , KASIDAS, Nadine
IPC分类号： G01N33/543 , G01N33/68 , G01N33/558 , G01N33/58
CPC分类号： G01N33/558 , G01N33/84 , G01N2800/324
摘要： A lateral flow assay device can produce a color when a metal ion reacts with a color forming regent, The metal ion can be present in a sample to be tested or in a reagent zone on the device. When the metal ion is present in a reagent zone on the device, the device can be used to measure the metal ion binding capacity of a component of a sample.
摘要翻译：当金属离子与成色剂反应时，侧流测定装置可以产生颜色。金属离子可以存在于要测试的样品中或在器件上的试剂区中。当金属离子存在于器件上的试剂区域中时，该器件可用于测量样品组分的金属离子结合能力。

7. 发明申请

WO2008059336A2 TESTING DEVICE AND METHOD 审中-公开
标题翻译：测试设备和方法
公开(公告)号：WO2008059336A2
公开(公告)日：2008-05-22
申请号：PCT/IB2007003417
申请日：2007-11-08
申请人： INVERNESS MEDICAL SWITZERLAND , TAYLOR DAVID
发明人： TAYLOR DAVID
IPC分类号： G01N33/487
CPC分类号： G01N33/48785
摘要： An assay device includes reader having an outer surface that is conductive.
摘要翻译：测定装置包括具有导电性的外表面的读取器。

8. 发明申请

WO2007110779A2 ASSAY DEVICE AND METHOD 审中-公开
标题翻译：测定装置和方法
公开(公告)号：WO2007110779A2
公开(公告)日：2007-10-04
申请号：PCT/IB2007/001756
申请日：2007-03-29
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , LOWE, Phillip , KEATCH, Steven, Alexander , HOWELL, Steven , MARQUORDT, Claus , POLWART, Ruth , THOMSON, Alan, Kenneth
发明人： LOWE, Phillip , KEATCH, Steven, Alexander , HOWELL, Steven , MARQUORDT, Claus , POLWART, Ruth , THOMSON, Alan, Kenneth
CPC分类号： G01N33/558 , B01L3/5027 , B01L3/502715 , B01L3/502761 , B01L3/502769 , B01L9/527 , B01L2200/0621 , B01L2200/0668 , B01L2300/0636 , B01L2300/0645 , B01L2300/0672 , B01L2300/0816 , B01L2300/0867 , B01L2300/0887 , B01L2400/0406 , B01L2400/0683 , B01L2400/0688 , B01L2400/086 , G01N33/54326 , G01N33/54366 , G01N35/0098
摘要： An assay method and device can perform at least one (e.g., at least two) assays on a single aliquot of a sample liquid. The device can mix a sample liquid with assay reagents including magnetically susceptible particles. The device is configured to create a sample liquid-air interface with the sample liquid. The magnetically susceptible particles can be located (via an applied magnetic field) at the liquid-air interface when a second liquid contacts the interface to form a liquid-liquid interface. The magnetic particles travel across the liquid-liquid interface to the second liquid. The magnetically susceptible particles are configured to transport an analyte across the interface into the second liquid. An assay for the analyte is performed in the second liquid. An assay for another analyte can also be performed in the sample liquid.
摘要翻译：测定方法和装置可以在样品液体的单个等分试样上进行至少一个（例如，至少两个）测定。该装置可以将样品液体与包含磁敏感颗粒的测定试剂混合。该装置被配置为产生与样品液体的样品液 - 空界面。当第二液体接触界面以形成液 - 液界面时，磁敏感颗粒可以在液 - 空界面处（通过施加的磁场）定位。磁性颗粒穿过液体 - 液体界面移动到第二液体。磁敏感颗粒被配置成将分析物通过界面输送到第二液体中。在第二液体中进行分析物的测定。也可以在样品液体中进行另一分析物的测定。

9. 发明申请

WO2007110702A3 ASSAYS 审中-公开
公开(公告)号：WO2007110702A3
公开(公告)日：2007-10-04
申请号：PCT/IB2006/004158
申请日：2006-11-22
申请人： INVERNESS MEDICAL SWITZERLAND GMBH , RAJ, Balbir
发明人： RAJ, Balbir
IPC分类号： G01N33/558 , G01N33/58 , G01N33/76
摘要： Provided are assays and devices to detect a target compound in urine.

10. 发明申请

WO2007057744A3 FLUID RESERVOIR 审中-公开
标题翻译：流体储存
公开(公告)号：WO2007057744A3
公开(公告)日：2007-09-27
申请号：PCT/IB2006003206
申请日：2006-11-14
申请人： INVERNESS MEDICAL SWITZERLAND , PANESAR SATWINDER SINGH , HANNA COLIN , LANG DAVID KINNIBURGH , GILL ANDREW , MARQUORDT CLAUS
发明人： PANESAR SATWINDER SINGH , HANNA COLIN , LANG DAVID KINNIBURGH , GILL ANDREW , MARQUORDT CLAUS
IPC分类号： G01N33/68 , B01L3/00
CPC分类号： B01L3/502715 , B01L2200/16 , B01L2300/0672 , B01L2300/0816 , B01L2400/0478 , B01L2400/0481 , B01L2400/0683
摘要： Devices can include fluid reservoirs for storage of small amounts of liquid. Methods of removal of the liquid stored in a fluid reservoirs can include fluid activators such as an indentor, a slider, or a piston.
摘要翻译：设备可以包括用于储存少量液体的流体储存器。去除存储在流体储存器中的液体的方法可以包括流体活化剂，例如压头，滑块或活塞。

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