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1. 发明申请

WO1995025010A1 CONTAMINATION-PROOF SEALANT FILM AND PRODUCT FABRICATED THEREFROM 审中-公开
标题翻译：污染防护膜和其制造的产品
公开(公告)号：WO1995025010A1
公开(公告)日：1995-09-21
申请号：PCT/JP1995000410
申请日：1995-03-10
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , INOUE, Fujio , IZUMI, Masamitsu , KASHIYAMA, Shigetoshi
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： B32B27/28
CPC分类号： B32B27/08 , A61J1/10 , A61J1/2024 , A61J1/2027 , A61J1/2093 , B32B7/12 , B32B27/18 , B32B27/306 , B32B27/32 , B32B2309/105 , B32B2323/046 , B32B2439/80 , Y10T428/1341 , Y10T428/1383 , Y10T428/24967 , Y10T428/24975 , Y10T428/2826 , Y10T428/31913 , Y10T428/31928 , Y10T428/31935
摘要： A contamination-proof sealant film mainly used in the medical field, which is provided at least with the first layer as the innermost layer comprising at least one resin selected from the group consisting of linear low-density polyethylene, low-density polyethylene, polypropylene and polybutene-1, the second layer as an adhesive layer comprising non-crystalling polyolefin, adhesive polyolefin or an ethylene-vinyl acetate copolymer, and the third layer consisting of an ethylene-vinyl alcohol copolymer. The third layer functions as a barrier for preventing the contaminant from migrating from outside the third layer toward the first layer as the innermost layer.
摘要翻译：主要用于医疗领域的防污密封膜至少包含第一层作为最内层，其包含至少一种选自线性低密度聚乙烯，低密度聚乙烯，聚丙烯和聚丁烯-1，作为包含非结晶聚烯烃，粘合剂聚烯烃或乙烯 - 乙酸乙烯酯共聚物的粘合剂层的第二层和由乙烯 - 乙烯醇共聚物组成的第三层。第三层作为防止污染物从第三层外侧向第一层迁移的障碍起着最内层的作用。

2. 发明申请

WO1994016663A1 BICARBONATE-CONTAINING POWDERED MEDICINE STORAGE CONTAINER AND METHOD OF STABILIZING THE SAME MEDICINE 审中-公开
标题翻译：含有碳酸氢钙的药物储存容器及其相同药物的稳定化方法
公开(公告)号：WO1994016663A1
公开(公告)日：1994-08-04
申请号：PCT/JP1994000041
申请日：1994-01-14
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , INOUE, Fujio , IZUMI, Masamitsu , HAYASHI, Satoru
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： A61J01/00
CPC分类号： A61J1/00 , A61M1/167 , B65D75/38 , B65D81/24 , B65D81/266
摘要： This invention provides a method of stabilizing a bicarbonate-containing powdered medicine by employing the means for packing this powdered medicine in a water- and gas-permeable plastic container, and wrapping this container with a plastic packaging material having a water- and gas-non-permeability with a hollow space between the container and packaging material filled with carbon dioxide or provided therein with a carbon dioxide generating oxygen scavenger or a carbon dioxide saturation adsorbed drying agent; and a container for practicing this method. According to the present invention, its original object of mixing bicarbonate with a powdered material without causing the denaturation and deterioration of a bicarbonate-containing powdered medicine can be achieved.
摘要翻译：本发明提供了一种通过使用将该粉末药物包装在水和透气性塑料容器中的方法来稳定含碳酸氢盐的粉末状药物的方法，并且用具有水和气体非易失性的塑料包装材料包装该容器在容器和填充有二氧化碳的包装材料之间具有中空空间的透气性，或者在其中提供产生二氧化碳的除氧剂或二氧化碳饱和吸附的干燥剂; 和一个用于练习这种方法的容器。根据本发明，可以实现将碳酸氢盐与粉末状材料混合而不引起含碳酸氢盐粉末药物的变性和劣化的原始目的。

3. 发明申请

WO1994008782A1 MULTI-LAYERED FILM MATERIAL 审中-公开
标题翻译：多层膜材料
公开(公告)号：WO1994008782A1
公开(公告)日：1994-04-28
申请号：PCT/JP1993001501
申请日：1993-10-19
申请人： TOPPAN PRINTING CO., LTD. , OTSUKA PHARMACEUTICAL FACTORY, INC. , HIRAYAMA, Masahiro , INOUE, Fujio , IZUMI, Masamitsu , KASHIYAMA, Shigetoshi
发明人： TOPPAN PRINTING CO., LTD. , OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： B32B09/00
CPC分类号： B32B27/08 , A61J1/10 , A61M2207/00 , B32B7/12 , B32B27/306 , B32B27/32 , B32B2439/80
摘要： A multi-layered film material having a structure wherein a protective layer, a composite film comprising a polyvinyl alcohol film or a film of an ethylene/vinyl acetate copolymer saponificate and a silicon oxide deposition layer formed on the former, and a heat-sealable polyolefin layer are laminated. In this case, each of the layers is transparent and the silicon oxide layer is disposed on the side of the protective layer. The protective layer and the composite film, and the composite film and the heat-sealable polyolefin layer are laminated by an adhesive layer, respectively.
摘要翻译：具有以下结构的多层膜材料：其中保护层，包含聚乙烯醇膜的复合膜或乙烯/乙酸乙烯酯共聚物皂化物膜和在其上形成的氧化硅沉积层，以及可热封聚烯烃层叠。在这种情况下，各层是透明的，并且氧化硅层设置在保护层的一侧。保护层和复合膜以及复合膜和可热封聚烯烃层分别通过粘合层层压。

4. 发明申请

WO1992008434A1 MULTI-CHAMBER VESSEL 审中-公开
标题翻译：多层船只
公开(公告)号：WO1992008434A1
公开(公告)日：1992-05-29
申请号：PCT/JP1991001465
申请日：1991-10-28
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , INOUE, Fujio , FURUTA, Yasuo , KASHIYAMA, Shigetoshi
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： A61J01/00
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/2024 , A61J1/2027 , A61J1/2034 , A61J1/2041 , B65D81/266 , B65D81/3261 , B65D81/3266
摘要： A multi-chamber vessel used mainly in the medical field, in which the flexible plastic vessel proper is divided into a plurality of chambers with partitioning means permitting communication as required, at least one of a plurality of chambers composing the vessel proper is not provided with a cover whereas at least one other chamber is provided with a cover which covers this chamber through a sealed space and is composed of a flexible film having water- and gas-barrier functions, and at least any of desiccant and deoxidizer is contained in said sealed space, whereby the vessel is low in price, excellent in quality and performance, and, further, easy to discard.

5. 发明申请

WO1996017578A1 METHOD OF SUPPRESSING ADSORPTION OF SUBSTANCES DERIVED FROM CONTAINER MATERIAL ON DRUGS AND CONTAINER 审中-公开
标题翻译：抑制从容器中吸收的物质对药物和容器的吸附的方法
公开(公告)号：WO1996017578A1
公开(公告)日：1996-06-13
申请号：PCT/JP1995002487
申请日：1995-12-04
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , INOUE, Fujio , IZUMI, Masamitsu , HAYASHI, Satoru , YOSHIDA, Chieko
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： A61J01/00
CPC分类号： B65D81/2069 , A61J1/00 , B65D81/24 , Y10S206/828 , Y10T428/1314 , Y10T428/1352 , Y10T428/292
摘要： A method of suppressing adsorption of various substances derived from a drug container material on a powdery or solid drug in putting the same into a drug container that is partially or wholly constituted of a rubbery or plastic material, wherein the inside of the container is put in an atmosphere of a lower alcohol. This method enables a powdery or solid drug to be preserved safely for long without generating fine insoluble particles or muddy substances (poor liquefaction) due to the container material in preparing solutions and without the loss of the active ingredients caused by the decomposition, denaturation or degradation thereof and the generation of toxic substances caused thereby.
摘要翻译：抑制由药物容器材料衍生的各种物质吸附在粉状或固体药物上的方法，将其放入部分或全部由橡胶或塑料材料构成的药物容器中，其中将容器的内部放入低级酒精的气氛。该方法使得粉末状或固态药物长时间保存而不会由于容器材料在制备溶液中而产生细小的不溶性颗粒或泥质物质（液化不良），而且不会由于分解，变性或降解而导致活性成分的损失。并且由此引起的有毒物质的产生。

6. 发明申请

WO1994017772A1 MULTILAYERED MEDICAL FILM AND DOUBLE-COMPARTMENT CONTAINER 审中-公开
标题翻译：多层医用膜和双层容器
公开(公告)号：WO1994017772A1
公开(公告)日：1994-08-18
申请号：PCT/JP1994000143
申请日：1994-02-02
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , INOUE, Fujio , IZUMI, Masamitsu , KASHIYAMA, Shigetoshi
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： A61J01/05
CPC分类号： B32B27/08 , A61J1/10 , A61J1/2024 , A61J1/2093 , B32B27/32 , B32B2250/242 , B32B2307/72 , B32B2439/80 , Y10T428/1359 , Y10T428/24992 , Y10T428/31909
摘要： A multilayered medical film mainly used for forming a double-compartment medical container and excellent in heat resistance, transparency, flexibility, impact resistance, and easiness in peeling and sealing, which film is composed of: an inner layer formed from a resin mixture composed of an ethylene/ alpha -olefin copolymer having a density of 0.930-0.945 g/cm and polypropylene, an intermediate layer containing at least one mixed resin layer formed from a resin mixture, in a ratio of 1:5 to 2:1 by weight, of an ethylene/ alpha -olefin copolymer having a density of 0.920-0.945 g/cm and an ethylene/ alpha -olefin elastomer having a density of 0.880-0.890 g/cm , wherein the mixed resin layer accounts for at least 85 % of the whole intermediate layer in thickness, and an outer layer formed from an ethylene/ alpha -olefin copolymer having a density of 0.930-0.945 g/cm .
摘要翻译：一种主要用于形成双室医疗容器的多层医用膜，其耐热性，透明性，柔韧性，耐冲击性和易剥离密封性优异，该膜由以下组成的树脂混合物构成的内层：由密度为0.930-0.945g / cm 3的乙烯/α-烯烃共聚物和聚丙烯，含有至少一种由树脂混合物形成的混合树脂层的中间层，其比例为1:5至2:1 的密度为0.920-0.945g / cm 3的乙烯/α-烯烃共聚物和密度为0.880-0.890g / cm 3的乙烯/α-烯烃弹性体，其中混合树脂层占整个中间层厚度的至少85％，外层由密度为0.930-0.945g / cm 3的乙烯/α-烯烃共聚物形成。

7. 发明申请

WO1994007598A1 ADSORBENT FOR CELLULAR FIBRONECTIN, SEPARATION AND PURIFICATION OF FIBRONECTIN, AND PURIFICATION OF BLOOD 审中-公开
标题翻译：细胞纤维蛋白的吸收，纤维蛋白的分离和纯化，血液的纯化
公开(公告)号：WO1994007598A1
公开(公告)日：1994-04-14
申请号：PCT/JP1993001366
申请日：1993-09-22
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , NISSHINBO INDUSTRIES, INC. , KOMAI, Takashi , TAKENISHI, Soichiro , MIYASHITA, Keiichi , SAKASHITA, Eiji , KAMOGAWA, Hiroshi , INOUE, Fujio
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC. , NISSHINBO INDUSTRIES, INC.
IPC分类号： B01J20/24
CPC分类号： B01J20/24 , Y10S530/829
摘要： A selective adsorbent for cellular fibronectin (cFN) utilizing a nonwoven cellulose sulfate fiber fabric, and a method of separation and purification of FN in which an FN-containing material containing plasma fibronectin (pFN) and the cFN is brought into contact with the non-woven fabric to separate the pFN from the cFN. According to this method, the cFN can be separated from the pFN efficiently by a simple operation, and high purity pFN and cFN can be recovered at a high yield.
摘要翻译：使用非织造纤维素硫酸纤维织物的细胞纤维连接蛋白（cFN）的选择性吸附剂以及分离和纯化FN的方法，其中含有含有血浆纤连蛋白（pFN）和cFN的含FN材料与非接触式非织造织物接触，编织物将pFN与cFN分开。根据该方法，可以通过简单的操作将cFN与pFN进行有效分离，可以高产率回收高纯度的pFN和cFN。

8. 发明申请

WO1994006396A1 DRUG-PACKING POLYOLEFINIC MATERIAL, PROCESS FOR PRODUCING THE SAME, AND CONTAINER FOR DRUG PACKING 审中-公开
标题翻译：药物包装用聚合物材料，其制造方法和用于药物包装的容器
公开(公告)号：WO1994006396A1
公开(公告)日：1994-03-31
申请号：PCT/JP1993001257
申请日：1993-09-06
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , MITSUI PETROCHEMICAL INDUSTRIES, LTD. , INOUE, Fujio , IZUMI, Masamitsu , KASHIYAMA, Shigetoshi , TANAKA, Hiroshi
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC. , MITSUI PETROCHEMICAL INDUSTRIES, LTD.
IPC分类号： A61J01/00
CPC分类号： C08F6/005 , A61J1/10 , C08J5/18 , C08J2323/08 , C08L23/0815 , C08L23/12 , C08L23/00 , C08L2666/06
摘要： A drug-packing polyolefinic material containing at most 150 ppm of C12-C26 substances and being extremely reduced in the risk of adversely affecting the drugs packed therein.
摘要翻译：含有至多150ppm C12-C26物质的药物包装聚烯烃材料，并且极度降低其中包装的药物的不利影响的风险。

9. 发明申请

WO2007072942A9 CLASSIFYING SYSTEM AND FINE PARTICLE MEASURING DEVICE 审中-公开
标题翻译：分类系统和微粒测量装置
公开(公告)号：WO2007072942A9
公开(公告)日：2007-08-09
申请号：PCT/JP2006325593
申请日：2006-12-22
申请人： SHIMADZU CORP , OKUDA DAIJI , OKUDA HIROSHI , INOUE FUJIO
发明人： OKUDA DAIJI , OKUDA HIROSHI , INOUE FUJIO
IPC分类号： G01N15/02 , G01N15/06 , G01N27/60
CPC分类号： G01N15/0266
摘要： A classifying system for retrieving a specified particle size range after being classified. In a preferable embodiment, an electric field for classifying charged fine particles according to electric mobility is generated by a center electrode (3) and an outside electrode (4). A sheath gas supply unit (7) is provided at the upper portion of a housing (1). An aerosol supply unit (11), having an introducing port (11a) on the outside electrode (4) side in a classifying region (5) and supplying charged aerosol at a constant flow rate from the introducing port (11a), is provided. A large-particle-size-side discharge unit (13), having a discharge port (13a) on the outside electrode (4) side and discharging that part of charged fine particles in classified charged aerosol that has at least a specified particle size at a constant flow rate along with part of sheath gas, is provided on the downstream side in a sheath gas flow in the classifying region (5). A detector (18) for detecting as an electric quantity the remaining number of charged fine particles fed along with sheath gas is disposed at the lower portion of the housing (1).
摘要翻译：分类系统，用于在分类后检索指定的粒度范围。在优选的实施方式中，通过中心电极（3）和外部电极（4）产生用于根据电迁移率对带电微粒进行分类的电场。护套气体供给单元（7）设置在壳体（1）的上部。一种气雾剂供应单元（11），其在分类区域（5）的外侧电极（4）侧具有引入口（11a），并且从引入口（11a）以恒定流量供给带电气溶胶。一种大粒径侧排出单元（13），其在外侧电极（4）侧具有排出口（13a），并将具有至少规定粒径的分级带电气雾剂的部分带电微粒排出在分类区域（5）中的鞘气流中的下游侧设置有恒定的流量以及鞘气体的一部分。一种用于检测作为电量的检测器（18），其中壳体（1）的下部设置有与护套气体一起供给的带电微粒子的剩余数量。

10. 发明申请

WO1993021890A1 VESSEL HAVING A PLURALITY OF CHAMBERS 审中-公开
标题翻译：具有多种泡沫的船只
公开(公告)号：WO1993021890A1
公开(公告)日：1993-11-11
申请号：PCT/JP1993000558
申请日：1993-04-28
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , INOUE, Fujio , IZUMI, Masamitsu , KASHIYAMA, Shigetoshi
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： A61J01/00
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/2024 , B65D81/3266
摘要： A vessel having a plurality of chambers for use mainly in the medical field, wherein the interior of the main body of a flexible plastic vessel is partitioned into a plurality of chambers by use of a partitioning means permitting suitable communication between the chambers, out of respective vessel portions of the main body of the plastic vessel, which constitute the plurality of chambers, at least one vessel portion has no cover and at least another vessel portion has a cover, said cover covering the peripheral surface of said vessel portion through a tightly sealed space portion and being formed of flexible film having moisture-proof and gas barrier properties, so that the easily disposable vessel having the plurality of chambers, which is inexpensive and high in quality and performance can be provided.
摘要翻译：一种具有主要用于医疗领域的多个室的容器，其中柔性塑料容器的主体的内部通过使用分隔装置分隔成多个室，所述分隔装置允许在相应的腔室之间适当的连通构成多个室的塑料容器的主体的容器部分至少一个容器部分没有盖，并且至少另一个容器部分具有盖，所述盖通过密封地覆盖所述容器部分的周面空间部分并且由具有防潮和阻气性的柔性膜形成，从而可以提供廉价且高质量和高性能的具有多个室的容易一次性容器。

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