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1. 发明申请

WO2004007311A2 METHOD AND APPARATUS FOR METERING LIQUID NUTRITIONAL SUPPLEMENTS 审中-公开
标题翻译：测量液体营养补充剂的方法和装置
公开(公告)号：WO2004007311A2
公开(公告)日：2004-01-22
申请号：PCT/US0321486
申请日：2003-07-09
申请人： REMINGTON HEALTH PRODUCTS L L
发明人： STEELE WILLIAM IV , LIVINGSTON PHILLIP D , ZIERHUT CLARENCE D
IPC分类号： B65D1/02 , A61J7/00 , B65D23/10 , B65D41/04 , B65D41/26
CPC分类号： B65D41/26 , B65D23/102 , Y10S206/828 , Y10S215/07
摘要： A method and apparatus for metering a liquid nutritional supplement is disclosed and provides a liquid dispenser having a body that contains a predetermined number of single dosages of the liquid nutritional supplement, a cap, such as a child-resistant cap, coupled to a neck portion of the body, and a dosage cup coupled to the cap. The dosage cup has at least four axial shoulders on an inside surface thereof that each has an engaging surface adapted to engage axial ridges of the cap. The dosage cup is coupled to the cap such that a force that is greater, by a predetermined amount, than the weight of the dosage cup is required to remove the dosage cup from the cap, and providing the dosage cup with an indicator adapted to indicate one of the single dosages of the liquid nutritional supplement to be consumed by a user for a predetermined time period.
摘要翻译：公开了一种用于计量液体营养补充剂的方法和装置，并提供了一种液体分配器，其具有包含预定数量的单一剂量的液体营养补充物的主体，联接到颈部的帽，例如耐儿童帽的身体，以及联接到帽的剂量杯。剂量杯在其内表面上具有至少四个轴向肩部，其每个具有适于接合帽的轴向脊的接合表面。剂量杯联接到帽上，使得需要比剂量杯的重量更大的预定量的力以从帽中移除剂量杯，并且为剂量杯提供适于指示的剂量杯在用户预定时间段内消耗的液体营养补充剂的单剂量之一。

2. 发明申请

WO2003068136A1 医療用複室容器审中-公开
标题翻译：医用多腔容器
公开(公告)号：WO2003068136A1
公开(公告)日：2003-08-21
申请号：PCT/JP2003/000058
申请日：2003-01-08
申请人：株式会社大塚製薬工場 , 岡実 , 大西賢 , 濵崎新 , 中尾修 , 杉岡義弘
发明人：岡実 , 大西賢 , 濵崎新 , 中尾修 , 杉岡義弘
IPC分类号： A61J1/05
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/2024 , Y10S206/828 , Y10S383/906
摘要： A medical multi-chamber container (1), comprising a container body (3) having first and second storage chambers (10, 11) for storing chemicals and a partitioning weak seal part (20) for partitioning the storage chambers (10, 11) from each other, and a delivery part (32) fitted into the container body (3) and allowing the chemicals to be delivered from the storage chamber (11), the container body (3) further comprising a delivery weak seal part (21) partitioning the second storage chamber (11) from the delivery part (32) and unsealably formed when used, wherein the partitioning weak seal part (20) is unsealably formed so as to allow the storage chambers (10, 11) to communicate with each other when used, characterized in that the unsealing strength of the delivery weak seal part (21) is smaller than that of the partitioning weak seal part (20).
摘要翻译：一种医用多室容器（1），包括：容器主体（3），具有用于储存化学物质的第一和第二储存室（10,11）和用于分隔存储室（10,11）的分隔弱密封部分（20）以及装配到容器主体（3）中并允许化学品从储存室（11）输送的输送部分（32），容器主体（3）还包括输送弱密封部分（21）将第二储存室（11）从输送部分（32）分开并在使用时不可密封地形成，其中分隔弱密封部分（20）是不可密封地形成的，以便使储存室（10,11）彼此连通当使用时，其特征在于，输送弱密封部（21）的开封强度小于分隔弱密封部（20）的开封强度。

3. 发明申请

WO2003066152A2 VIAL ADAPTER HAVING A NEEDLE-FREE VALVE FOR USE WITH VIAL CLOSURES OF DIFFERENT SIZES 审中-公开
标题翻译：具有无缝阀的VIAL适配器与不同尺寸的垂直封闭使用
公开(公告)号：WO2003066152A2
公开(公告)日：2003-08-14
申请号：PCT/US2003/003684
申请日：2003-02-07
申请人： ALARIS MEDICAL SYSTEMS, INC.
发明人： LEINSING, Karl, R.
IPC分类号： A61M39/00
CPC分类号： A61J1/2089 , A61J1/201 , A61J1/2044 , A61J1/2055 , A61J1/2096 , A61M39/045 , A61M39/10 , A61M39/26 , B01L3/50825 , B01L2200/023 , B01L2200/026 , B01L2300/049 , Y10S206/828 , Y10S215/03 , Y10S604/905
摘要： A vial adapter having a needle-free valve, a sharpened cannula used to perforate a vial's rubber stopper, and a circular array of claws of different lengths to engage vial closures of different diameters. The array of claws includes a first set of claws each having a first length extending inwardly from the periphery of the housing of the adapter and a second set of claws alternating with the first set of claws and each having a longer length. The second set of claws are mounted so that they deflect and plastically deform out of the way in the case where the adapter is engaged with a vial that exceeds a predetermined size. The housing includes a shroud that is at least as long as the sharpened cannula to protect medical personnel who use the adapter from inadvertent punctures. The needlefree valve includes a resiliently deformable piston element with a naturally open bore. The interior of the piston provides a fluid flow path through the adapter. In one embodiment, the first set of claws of the adapter may be used with a vial closure of at approximately 20 mm in diameter and the second set of claws may be used with a vial closure of approximately 13 to 17 mm in diameter.
摘要翻译：具有无针阀的小瓶适配器，用于穿孔小瓶的橡胶塞的尖锐插管和不同长度的圆形圆形阵列以接合不同直径的小瓶盖。爪阵列包括第一组爪，每组爪具有从适配器壳体的周边向内延伸的第一长度和与第一组爪交替并且每个具有较长长度的第二组爪。第二组爪被安装成使得它们在适配器与超过预定尺寸的小瓶接合的情况下偏转和塑性变形。壳体包括至少与尖锐插管一样长的护罩，以保护使用适配器的医务人员无意中穿刺。无针阀包括具有自然开口孔的可弹性变形的活塞元件。活塞的内部提供通过适配器的流体流动路径。在一个实施例中，适配器的第一组爪可以与直径为大约20mm的小瓶盖一起使用，并且第二组爪可以与直径约13至17mm的小瓶封闭件一起使用。

4. 发明申请

WO1997041902A1 DUAL-FILLED TWIN BAG, A PACKAGE AND A METHOD FOR FORMING A PACKAGE FOR ADMINISTERING A SOLUTION 审中-公开
标题翻译：双填充双袋，包装和形成用于管理溶液的包装的方法
公开(公告)号：WO1997041902A1
公开(公告)日：1997-11-13
申请号：PCT/US1997006919
申请日：1997-04-25
申请人： BAXTER INTERNATIONAL INC.
发明人： BAXTER INTERNATIONAL INC. , KEILMAN, Michael, R. , MAKARYK, Walter, A. , GIERTYCH, Joseph, A.
IPC分类号： A61M01/28
CPC分类号： A61M1/28 , A61J1/00 , A61M1/1668 , A61M1/1686 , Y10S128/24 , Y10S206/828 , Y10T436/108331
摘要： A dual-filled twin bag, a packaging including the twin bag, and a method for forming the packaged twin bags are provided. Each of two bags, a solution bag (10) and a drain bag (12) for a system used for a peritoneal dialysis procedure, are filled, at least partially, with a solution (14). A tubing set (16) connects the two filled bags (10, 12) and may also be filled with solution (14) which is added to the bags (10, 12) and the tubing set (16) during the manufacturing process. Alternatively, the tubing set (16) may be filled with air. The tubing set (16) is sandwiched between the solution bag (10) and the drain bag (12) and subsequently packaged in an overpouch (24). The method for forming the package including the bags filled with solution is simplified and the overall package size is reduced due to the sandwiched tubing set (16) between the solution bags (10, 12) and the provision of solution in both bags (10, 12).
摘要翻译：提供双填充双袋，包括双包的包装以及用于形成包装的双袋的方法。至少部分地用溶液（14）填充两个袋子中的每个袋，溶液袋（10）和用于腹膜透析程序的系统的排液袋（12）。管道组（16）连接两个填充的袋（10,12），并且还可以填充溶液（14），其在制造过程中被添加到袋（10,12）和管组（16）中。或者，管组（16）可以填充空气。管套（16）夹在溶液袋（10）和排放袋（12）之间，随后包装在一个外袋（24）中。用于形成包括填充有溶液的袋的包装的方法被简化，并且由于溶液袋（10,12）之间的夹套管组（16）和在两个袋（10,12）中提供溶液，整体包装尺寸减小， 12）。

5. 发明申请

WO1997025321A2 SUBSTITUTED PHENYL COMPOUNDS AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN 审中-公开
标题翻译：取代的苯基化合物及其衍生物，其调节内皮素的活性
公开(公告)号：WO1997025321A2
公开(公告)日：1997-07-17
申请号：PCT/US1997000366
申请日：1997-01-03
申请人： TEXAS BIOTECHNOLOGY CORPORATION
发明人： TEXAS BIOTECHNOLOGY CORPORATION , CHAN, Ming, Fai , BALAJI, Vitukudi, Narayanaiyengar , CASTILLO, Rosario, Silverstre , KOIS, Adam , RAJU, Bore, Gowda , WU, Chengde
IPC分类号： C07D317/48
CPC分类号： A61K31/506 , A61K31/192 , A61K31/36 , A61K31/505 , C07D239/60 , C07D317/64 , C07D405/14 , Y10S206/828
摘要： Methods, compositions, and compounds and uses of the compounds and compositions for modulating the activity of an endothelin peptide are provided. The uses and methods employ compositions that contain compounds of formula (I), where X and Y are selected from groups that include O, S, and NH; and Ar , Ar and Ar are independently selected from substituted or unsubstituted groups that inlcude 5 to 6 membered aryl groups and heteroaryl groups that contain one or two heteroatom(s). Compositions and compounds used in the methods are also provided. Uses and methods are effected by contacting endothelin receptors with one or more of the compounds or with compositions containing one or more of the compounds prior to, simultaneously with, or subsequent to contacting the receptors with an endothelin peptide.
摘要翻译：提供了化合物和组合物用于调节内皮肽肽活性的方法，组合物和化合物及其用途。用途和方法使用包含式（I）化合物的组合物，其中X和Y选自包括O，S和NH的基团; 和Ar 1，Ar 2和Ar 3独立地选自包含5至6元芳基和含有一个或两个杂原子的杂芳基的取代或未取代的基团。还提供了方法中使用的组合物和化合物。使用和方法通过使内皮素受体与一种或多种化合物或含有一种或多种化合物的组合物在使受体与内皮素肽接触之前，同时或之后接触来实现。

6. 发明申请

WO2007099120A1 A METHOD AND AN APPARATUS FOR STERILIZING PACKAGING MATERIAL 审中-公开
标题翻译：一种灭菌包装材料的方法和装置
公开(公告)号：WO2007099120A1
公开(公告)日：2007-09-07
申请号：PCT/EP2007/051900
申请日：2007-02-28
申请人： NOVO NORDISK A/S , HANSEN, Lasse , NØRSKOV, Anders Døssing , JEPPESEN, Per , CHRISTENSEN, Signe Agnete
发明人： HANSEN, Lasse , NØRSKOV, Anders Døssing , JEPPESEN, Per , CHRISTENSEN, Signe Agnete
IPC分类号： A61L2/00 , A61L2/08 , B65B55/00 , B65B55/08 , B65B55/02
CPC分类号： B65B55/08 , A61L2/0011 , A61L2/0035 , A61L2/081 , A61L2/085 , A61L2/087 , A61L2/10 , A61L2/24 , A61L2202/122 , Y10S206/828
摘要： A method and an apparatus for sterilizing packaging material for use in packaging for protein containing products, such as food products or medical drugs. The packaging material is sterilized by irradiating it using a beam of ionizing radiation, such as an electron beam or a beam of gamma rays. Afterwards, the packaging material is processed in such a manner that protein reactive substances or compounds formed in the packaging material during the irradiation step are at least partly removed or rendered inreactive with respect to proteins. The processing step may advantageously be performed by heating the packaging material. Preferably, the processing step involves accelerating diffusion from the packaging material of protein reactive substances or compounds. Since the protein reactive substances or compounds are removed or rendered inreactive with respect to proteins, degradation of the product which is later stored in the packaging material is considerably reduced. The packaging material needs to be stored under sterile conditions for a shorter period of time. Thereby the space needed for sterile storage, as well of the risk of contamination, is considerably reduced.
摘要翻译：一种用于消毒用于包装蛋白质的产品如食品或医药的包装材料的方法和装置。通过使用诸如电子束或伽马射线的电离辐射束照射包装材料来消毒包装材料。之后，将包装材料加工成使得在照射步骤期间在包装材料中形成的蛋白质反应性物质或化合物至少部分地被去除或对蛋白质具有反应性。加工步骤可有利地通过加热包装材料来进行。优选地，加工步骤包括加速来自蛋白质反应性物质或化合物的包装材料的扩散。由于蛋白质反应性物质或化合物相对于蛋白质被去除或呈现反应性，所以后来储存在包装材料中的产品的降解会大大降低。包装材料需要在无菌条件下储存较短的时间。因此，无菌储存所需的空间以及污染风险大大降低。

7. 发明申请

WO2005035032A8 FLEXIBLE CONTAINER WITH A FLEXIBLE PORT AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有柔性端口的柔性集装箱及其制造方法
公开(公告)号：WO2005035032A8
公开(公告)日：2005-07-14
申请号：PCT/US0331013
申请日：2003-09-23
申请人： BRAUN MEDICAL INC
发明人： YOUNG HARVEY THEODORE
IPC分类号： A61F5/44 , A61J1/05 , A61J1/10 , A61M5/32 , A61M19/00 , B65D33/16 , B65D75/00
CPC分类号： A61J1/10 , A61F5/4405 , Y10S206/828 , Y10T29/49826
摘要： A flexible container is disclosed incorporating flexible front and rear sheets and one or more container ports disposed in between the sheets. The one or more container ports each has a pliable attachment flange and an integrally molded nozzle. The pliable attachment flange has a first configuration whereby the attachment flange collapses to enable heat sealing the attachment flange to the sheets and thereafter substantially recovers its shape to provide a fluid pathway with the port. Various terminal ports, terminal caps, and rubber septums may be useable with the one or more container ports.
摘要翻译：公开了一种柔性容器，其结合了柔性前片和后片以及布置在片之间的一个或多个容器端口。一个或多个容器端口各自具有柔韧的附接凸缘和整体模制的喷嘴。柔韧的连接凸缘具有第一构造，由此连接凸缘折叠以使得能够将连接凸缘热密封到片材，并且此后基本上恢复其形状以提供具有端口的流体通路。各种终端口，终端盖和橡胶隔膜可以与一个或多个容器端口一起使用。

8. 发明申请

WO2005035032A1 FLEXIBLE CONTAINER WITH A FLEXIBLE PORT AND METHOD FOR MAKING THE SAME 审中-公开
标题翻译：具有柔性端口的柔性容器及其制造方法
公开(公告)号：WO2005035032A1
公开(公告)日：2005-04-21
申请号：PCT/US2003/031013
申请日：2003-09-23
申请人： B. BRAUN MEDICAL INC.
发明人： YOUNG, Harvey, Theodore
IPC分类号： A61M5/32
CPC分类号： A61J1/10 , A61F5/4405 , Y10S206/828 , Y10T29/49826
摘要： A flexible container is disclosed incorporating flexible front and rear sheets and one or more container ports disposed in between the sheets. The one or more container ports each has a pliable attachment flange and an integrally molded nozzle. The pliable attachment flange has a first configuration whereby the attachment flange collapses to enable heat sealing the attachment flange to the sheets and thereafter substantially recovers its shape to provide a fluid pathway with the port. Various terminal ports, terminal caps, and rubber septums may be useable with the one or more container ports.
摘要翻译：公开了一种柔性容器，其结合了柔性前片和后片以及设置在片之间的一个或多个容器口。一个或多个容器端口各自具有柔韧的附接凸缘和整体模制的喷嘴。柔韧的连接凸缘具有第一构型，由此附接凸缘塌陷，以使得能够将附接凸缘热密封到薄片上，然后基本上恢复其形状以提供与端口的流体通路。各种终端端口，端子帽和橡胶隔膜可以与一个或多个容器端口一起使用。

9. 发明申请

WO02074374A9 FLUID FILLED AMPOULES AND METHODS FOR THEIR USE IN AEROSOLIZERS 审中-公开
标题翻译：流体填充电极及其在气溶胶中的使用方法
公开(公告)号：WO02074374A9
公开(公告)日：2002-12-27
申请号：PCT/US0208380
申请日：2002-03-19
申请人： AEROGEN INC
发明人： LOEFFLER JOSEPH P , POYNTER RICHARD Q , RAPP DAVID , KLIMOWICZ MICHAEL
IPC分类号： A61J1/06 , A61M15/00 , B05B17/06 , B65D1/09 , A61M16/00
CPC分类号： A61M15/0085 , A61J1/065 , A61J2205/10 , A61J2205/60 , A61M15/0028 , A61M15/0031 , A61M15/009 , A61M2205/6045 , A61M2205/6054 , B05B17/0607 , B65D1/095 , B65D2203/00 , Y10S206/828 , Y10S215/03
摘要： An ampoule (10) designed for holding fluid and adapted for use in an aerosolization device having two opposing ends (14 & 16) and a sealed interior (18). One end (14) having a movable shroud (24) and removable tab (22) for creating a drain vent and an opposing end (16) having a removable tab (30) for to create a drain vent.
摘要翻译：安瓿（10），设计用于保持流体并适用于具有两个相对端（14和16）和密封内部（18）的雾化装置。一端（14）具有可移动护罩（24）和用于产生排水通道的可拆卸突片（22），以及具有用于产生排水口的可拆卸突片（30）的相对端（16）。

10. 发明申请

WO2002074373A1 CONVERTIBLE FLUID FEED SYSTEM WITH COMFORMABLE RESERVOIR AND METHODS 审中-公开
标题翻译：具有可变储层和方法的可变流体进料系统
公开(公告)号：WO2002074373A1
公开(公告)日：2002-09-26
申请号：PCT/US2002/008379
申请日：2002-03-19
申请人： AEROGEN, INC.
发明人： LOEFFLER, Joseph, P. , RAPP, David , BRIONES, Victor , BITDINGER, Ralf , KLIMOWICZ, Michael
IPC分类号： A61M15/00
CPC分类号： A61M15/0028 , A61M15/0031 , A61M15/0033 , A61M15/0085 , B05B17/0646 , Y10S206/828
摘要： An aerosolizer feed system (10/12) utilizing an ampoule containing liquid including a housing (28) with an ampoule retaining region (42) and a liquid receiving region (34) adapted to receive liquid dispensed from an ampoule (46).
摘要翻译：一种利用含安瓿的液体的气雾剂进料系统（10/12），其包括具有安瓿保持区域（42）的壳体（28）和适于接收从安瓿（46）分配的液体的液体接收区域（34）。

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