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1. 发明申请

WO1997041820A1 DISPENSER UNIT, PROCESS FOR MANUFACTURING THE SAME AND ITS USE 审中-公开
标题翻译：配电单元，其制造方法相同，它们的用途
公开(公告)号：WO1997041820A1
公开(公告)日：1997-11-13
申请号：PCT/DE1997000837
申请日：1997-04-25
申请人： SENGEWALD VERPACKUNGEN GMBH , STRASSMANN, Günther
发明人： SENGEWALD VERPACKUNGEN GMBH
IPC分类号： A61J01/00
CPC分类号： B32B27/08 , A61J1/10 , A61M2207/00 , B29C65/02 , B29C65/08 , B29C65/14 , B29C65/1425 , B29C65/4815 , B29C65/4845 , B29C65/5021 , B29C65/5057 , B29C66/1122 , B29C66/133 , B29C66/24221 , B29C66/53262 , B29C66/71 , B29C66/723 , B29C66/72341 , B29L2009/00 , B29L2031/7148 , B32B27/32 , B32B27/365 , B32B2439/46 , B29K2077/00 , B29K2069/00 , B29K2027/06 , B29K2023/12 , B29K2023/083 , B29K2023/06 , B29K2021/003 , B29K2009/06
摘要： A dispenser unit has a flexible polymer bag, a joining part (10, 11) and a stiff hard part (20). The joining part has an inner layer (11) welded to the hard part and an outer polymer layer (10) welded to the inner material of the flexible bag. The inner material (30) of the flexible bag and the outer material of the joining part (10) are the same and are joined in such a way that they may be thermally sterilised. A process for manufacturing this dispenser unit has a step of coextrusion of the multilayered bag material, a step of coextrusion of the multilayered joining part, and steps for sealing the bag material, sealing the multilayered joining part and sealing the hard part. Also disclosed is the use of this dispenser unit for dispensing liquids, in particular aqueous liquids for human or animal medicine or in the food industry.
摘要翻译：本发明涉及一种分配单元，其具有柔性聚合物袋，连接部（10，11）和不灵活的硬质部分（20），其中，所述连接部分具有一个焊接到硬质部分内层（11）和一个与所述柔性袋外聚合物层的内部材料焊接（10）并且其中，所述柔性袋的内部材料（30）和连接部件（10）的外部材料是相同的并且是热灭菌的进一步的工艺连接，以便产生相同的，其包括多层袋材料的共挤出，多层连接部的共挤出的步骤，密封袋材料的密封多层连接部分和硬质部分Einsieglen及其作为递送装置用于液体，特别是水基流体用于人类或兽医医学或食品目的的用途。

2. 发明申请

WO1997020536A1 DEVICE FOR PREPARING A MEDICINAL SOLUTION RECONSTITUTED FROM TWO COMPONENTS 审中-公开
标题翻译：用于制备从两个组件重新构建的药物溶液的装置
公开(公告)号：WO1997020536A1
公开(公告)日：1997-06-12
申请号：PCT/CH1996000429
申请日：1996-12-04
申请人： MEYER, Gabriel , MEYER, Grégoire
IPC分类号： A61J01/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1475 , A61J1/201 , A61J1/2013 , A61J1/2017 , A61J1/2058 , A61J1/2065 , A61J1/2075 , A61J1/2082 , A61J1/2086 , A61J1/2096
摘要： A device (10) for preparing a liquid medicinal solution reconstituted from two components of which at least one is liquid, both components at first being stored in two respective separate sterilised hermetically sealed containers (15, 16). One of the components is an active substance and the other is the active or neutral diluent liquid component. The device comprises a central portion provided with a cannula (17), two container housings (13, 14) on either side of the central portion, and a channel having a first end opening for communication with the container (16) containing said active substance, and a second end opening for connection to a coupling for transferring said reconstituted liquid medicinal substance. The cannula (17) is arranged to establish communication between the two containers placed head-to-tail in the housings (13, 14), and coaxial with said containers, and comprises a first end projecting into the diluent container (15) substantially in the region of the outlet thereof, and a second end projecting into the active substance container (16) substantially in the central portion thereof. The volume of said container is selected to be more than twice the volume of the reconstituted liquid medicinal substance.
摘要翻译：一种用于制备从其两个组分重构的液体药用溶液的装置（10），其中至少一种是液体，首先将两种组分储存在两个相应的单独的灭菌密封容器（15,16）中。组分之一是活性物质，另一种是活性或中性稀释液体组分。该装置包括设置有插管（17）的中心部分，在中心部分的任一侧上的两个容器壳体（13,14）和具有第一端部开口的通道，该第一端部开口用于与容纳物（16）连通，，以及用于连接到用于转移所述重构液体药物的联接器的第二端开口。插管（17）被布置成在两个容器（13,14）之间建立头与尾之间的两个容器之间的连通，并与所述容器同轴，并且包括基本上以其出口的区域和基本上在其中心部分突出到活性物质容器（16）中的第二端。所述容器的体积选择为重构液体药物的体积的两倍以上。

3. 发明申请

WO1996040037A1 MULTI-PURPOSE VIALS FOR USE IN HYPODERMIC ADMINISTRATIONS AND DRUG DELIVERY SYSTEMS 审中-公开
标题翻译：用于血液管理和药物输送系统的多用途阴离子
公开(公告)号：WO1996040037A1
公开(公告)日：1996-12-19
申请号：PCT/US1996009338
申请日：1996-06-05
申请人： ABBOTT LABORATORIES
发明人： ABBOTT LABORATORIES , CARVETH, Peter, C. , PYTEL, Stanley, F.
IPC分类号： A61J01/00
CPC分类号： A61J1/2096 , A61J1/10 , A61J1/1406 , A61J1/1418 , A61J1/1468 , A61J1/1475 , A61J1/18 , A61J1/201 , A61J1/2089 , B65D51/002 , B65D2251/0015 , B65D2251/0075
摘要： The present invention relates to multi-purpose vials and a process of making them. The multi-purpose vials may be used in hypodermic administrations of drug or as part of a drug delivery system.
摘要翻译：本发明涉及多用途小瓶及其制造方法。多用途小瓶可用于皮下注射药物或作为药物递送系统的一部分。

4. 发明申请

WO1996017577A1 METHOD FOR COLLECTING AND PROCESSING BLOOD FOR A BLOOD BANK, APPARATUS SUITABLE THEREFOR AND USE OF THE APPARATUS 审中-公开
标题翻译：程序抽取和制备血液供应，适当的设备和装置的用途
公开(公告)号：WO1996017577A1
公开(公告)日：1996-06-13
申请号：PCT/EP1995004675
申请日：1995-11-28
申请人： HERAEUS INSTRUMENTS GMBH , NAGELS, Hans-Otto
发明人： HERAEUS INSTRUMENTS GMBH
IPC分类号： A61J01/00
CPC分类号： A61J1/10 , A61J1/12 , A61J1/16 , Y10T436/25375
摘要： In the known methods for collecting and processing blood for a blood bank, at least one blood bag, which is packed sterilely in a package, is filled with blood and then transported in a transport container. The apparatus used for this comprises a sterile package for at least one blood bag, having a completely enclosed interior space to hold the blood bag and a closure element used to open up the interior space. To device on this basis a method that allows simple and sterile collection and processing of the blood for storage and to provide a suitable apparatus therefor, enabling the blood for storage to be handled with little expenditure of work and low risk of contamination, the invention proposes with respect to the method that the package be used as transport container and regarding the apparatus that the interior space has a volume of at least 500 ml or can be expanded to at least 500 ml by applying an internal pressure directed outwards from the interior space, and that the interior space can be closed by means of the closure element.
摘要翻译：在用于去除和用于血液产品的处理的已知方法中，至少一个无菌包装中充满血液包装血袋，随后在容器中运输。为了这个目的，使用的设备包括一个无菌包装具有用于接收封闭在血袋和用于打开所述内部空间中的封闭元件的所有侧面的内部的至少一个血液袋。要指定此基础上，其允许简单且无菌的采样和制备的血液制品的方法和用于此提供可用的合适的设备，其允许血液制品很少的努力和污染的风险低的处理，所以建议，在该方法的条件是，作为运输容器，包装被使用，并且相对于该内部空间的体积至少为500 ml，或可以通过应用从内向外指引的内部压力被扩展到至少500毫升，并且内部被封闭元件来封闭所述装置。

5. 发明申请

WO1995013785A1 DECANTING DEVICE FOR MEDICAL OR PHARMACEUTICAL PRACTICE, FOR EXAMPLE TO DECANT AN ACTIVE SUBSTANCE INTO A SOLUTION 审中-公开
标题翻译：传输设置中医药杂志，例如活性物质在溶液中
公开(公告)号：WO1995013785A1
公开(公告)日：1995-05-26
申请号：PCT/EP1994003770
申请日：1994-11-14
申请人： EICHLER, Christian , WOLFRING, Claudio
IPC分类号： A61J01/00
CPC分类号： A61J1/20 , A61J1/10 , A61J1/1475 , A61J1/201 , A61J1/2013 , A61J1/2058 , A61J1/2062 , A61J1/2089 , A61J1/2096
摘要： In a decanting apparatus which consists of an emptying device formed by a container (31) for an active substance concentrate and a dosing pump (12) and from whose active substance concentrate container (31) a set amount of active substance concentrate is extracted and conveyed into a collecting container (32), the invention provides that the containers (31, 32) and the emptying device with its dosing pump (12) are attached to a closed housing (13) and connected with a multipath distributor which alternately establishes first a connection between the active substance concentrate container (31) and the dosing pump (12) and then a connection between the dosing pump (12) and the collecting container (32).
摘要翻译：根据提供了本发明在由活性物质浓缩物容器的填充装置的，（31）（12）的转印装置和计量泵形成，并且从所述活性物质浓缩物容器（31）中的活性成分的浓缩物的预定量的移除，并转移到一个去除容器（32），与它的计量泵（12）和在一封闭的壳体（13）的容器（31，32）的填充装置连接，并与多路分配器，其交替地将活性物质浓缩物容器（31）与所述计量泵（12）和化合物将连接产生计量泵（12），以除去容器（32）。

6. 发明申请

WO1994016664A1 MULTIPLE CHAMBER CONTAINER 审中-公开
标题翻译：多腔室容器
公开(公告)号：WO1994016664A1
公开(公告)日：1994-08-04
申请号：PCT/US1994000546
申请日：1994-01-18
申请人： BAXTER INTERNATIONAL INC.
发明人： BAXTER INTERNATIONAL INC. , BALTEAU, Patrick , FAICT, Dirk , PELUSO, Francesco
IPC分类号： A61J01/00
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/2027 , A61M1/1668 , A61M1/1686 , A61M1/28
摘要： A multiple chamber container (10) for mixing and administering a plurality of products. The container (10) has at least two chambers (24, 26) separated by a seal line (22). A frangible connector (36) is situated between the two chambers (24, 26) for mixing the products contained within the chambers as desired. Each chamber (24, 26) has at least one port (28, 32) for filling of product into the chamber. The ports (28, 32) are located on the same exterior side of the container such that the chambers can be filled without folding the bag and by using existing filling equipment.
摘要翻译：一种用于混合和施用多个产品的多室容器（10）。容器（10）具有由密封线（22）分开的至少两个室（24,26）。一个易碎连接器（36）位于两个腔室（24,26）之间，用于根据需要混合容纳在腔室内的产品。每个室（24,26）具有用于将产品填充到室中的至少一个端口（28,32）。端口（28,32）位于容器的相同的外侧上，使得可以在不折叠袋子的情况下填充室并且使用现有的填充设备。

7. 发明申请

WO1994000094A1 A RECONSTITUTION DEVICE 审中-公开
标题翻译：重建设备
公开(公告)号：WO1994000094A1
公开(公告)日：1994-01-06
申请号：PCT/IE1993000035
申请日：1993-06-22
申请人： PURCELL, Mary, Therese , HOOD, Oliver, St. Clair , O'SULLIVAN, Niall, Anthony
IPC分类号： A61J01/00
CPC分类号： A61J1/2089 , A61J1/201 , A61J1/2013 , A61J1/2051
摘要： A reconstitution device (1) for coupling two containers, for example a vial (2) containing a drug and a flexible bag (3) containing a diluent, consisting of an enclosed two part housing (16, 17) within which is mounted a cannula (35) having two tips (37, 38). The device (1) is secured by a vial adaptor (20) to the vial (2) and by a bag adaptor (25) to the bag (3). After securing, the two parts of the housing (16, 17) are telescoped together causing the tips (37, 38) to pierce the vial (2) and bag (3) allowing communication between vial (2) and bag (3). The tips (37, 38) are not exposed at any time before, during or after use.
摘要翻译：一种用于联接两个容器的重建装置（1），例如包含药物的小瓶（2）和包含稀释剂的柔性袋（3），其由封闭的两部分壳体（16,17）组成，其中安装有插管（35）具有两个尖端（37,38）。装置（1）通过小瓶适配器（20）固定到小瓶（2）上，并通过袋适配器（25）固定到袋子（3）上。在固定之后，壳体（16,17）的两个部分被伸缩在一起，使得尖端（37,38）刺穿小瓶（2）和允许小瓶（2）和袋子（3）之间连通的袋子（3））。尖端（37,38）在使用前，使用期间或使用后的任何时候都不会露出。

8. 发明申请

WO1993021891A1 VESSEL FOR DRUG 审中-公开
公开(公告)号：WO1993021891A1
公开(公告)日：1993-11-11
申请号：PCT/JP1993000561
申请日：1993-04-28
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , TAKEDA CHEMICAL INDUSTRIES, LTD. , TATEISHI, Isamu , OKAMOTO, Hideshi , MAESAKI, Yoshiki , SHOJI, Hidekatsu , HAGIWARA, Takayuki , HATONO, Tetsuya
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC. , TAKEDA CHEMICAL INDUSTRIES, LTD.
IPC分类号： A61J01/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/1475 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2065 , A61J1/2072
摘要： An outer tube for housing a double-ended needle in a manner to be vertically slidable is air-tightly and detachably connected and fixed to a seal portion at the mouth portion of a vessel containing therein a solution, an inner tube for housing therein an inverted vial containing therein drug is connected to the top end of the outer tube in a manner to be movable from a shallow fitting position to a deep fitting position, and this connecting portion includes a seal ring air-tightly holding the inner and the outer tubes and retaining mechanism for retaining the inner tube in the shallow fitting position. With this arrangement, the vessel for the drug can be provided which has excellent shock-proof and vibration-proof properties during the transportation and storage, is capable of mixing and solving drugs by a simplified operation when in use, has a simplified overall construction and is separately disposable after the use.
摘要翻译：用于以可垂直滑动的方式容纳双头针的外管气密地且可拆卸地连接并固定到容纳有溶液的容器的口部处的密封部分，用于容纳其中的倒置的内管其中容纳有药物的小瓶以从浅配合位置移动到深配合位置的方式连接到外管的顶端，并且该连接部包括气密地保持内管和外管以及用于将内管保持在浅装配位置的保持机构。通过这种布置，可以提供在运输和储存期间具有优异的防震和防振性能的药物容器，在使用时能够通过简化的操作混合和解决药物，具有简化的总体结构和使用后分开放置一次。

9. 发明申请

WO1993021890A1 VESSEL HAVING A PLURALITY OF CHAMBERS 审中-公开
标题翻译：具有多种泡沫的船只
公开(公告)号：WO1993021890A1
公开(公告)日：1993-11-11
申请号：PCT/JP1993000558
申请日：1993-04-28
申请人： OTSUKA PHARMACEUTICAL FACTORY, INC. , INOUE, Fujio , IZUMI, Masamitsu , KASHIYAMA, Shigetoshi
发明人： OTSUKA PHARMACEUTICAL FACTORY, INC.
IPC分类号： A61J01/00
CPC分类号： A61J1/2093 , A61J1/10 , A61J1/2024 , B65D81/3266
摘要： A vessel having a plurality of chambers for use mainly in the medical field, wherein the interior of the main body of a flexible plastic vessel is partitioned into a plurality of chambers by use of a partitioning means permitting suitable communication between the chambers, out of respective vessel portions of the main body of the plastic vessel, which constitute the plurality of chambers, at least one vessel portion has no cover and at least another vessel portion has a cover, said cover covering the peripheral surface of said vessel portion through a tightly sealed space portion and being formed of flexible film having moisture-proof and gas barrier properties, so that the easily disposable vessel having the plurality of chambers, which is inexpensive and high in quality and performance can be provided.
摘要翻译：一种具有主要用于医疗领域的多个室的容器，其中柔性塑料容器的主体的内部通过使用分隔装置分隔成多个室，所述分隔装置允许在相应的腔室之间适当的连通构成多个室的塑料容器的主体的容器部分至少一个容器部分没有盖，并且至少另一个容器部分具有盖，所述盖通过密封地覆盖所述容器部分的周面空间部分并且由具有防潮和阻气性的柔性膜形成，从而可以提供廉价且高质量和高性能的具有多个室的容易一次性容器。

10. 发明申请

WO1992012696A1 SYSTEM FOR CREATING ON SITE, REMOTE FROM A STERILE ENVIRONMENT, PARENTERAL SOLUTIONS 审中-公开
标题翻译：创建现场系统，远离环境的环境，伙伴解决方案
公开(公告)号：WO1992012696A1
公开(公告)日：1992-08-06
申请号：PCT/US1991007151
申请日：1991-09-27
申请人： BAXTER INTERNATIONAL INC.
发明人： BAXTER INTERNATIONAL INC. , FINLEY, Mike , SCHARF, Mike , PACKARD, Jeff , KIPP, Jim , DUDAR, Tom , OWENS, Jim , BINDOKAS, Al
IPC分类号： A61J01/00
CPC分类号： A61J1/2089 , A61J1/10 , A61J1/2086
摘要： The present invention provides a system and method for creating on site, remote from a sterile environment, parenteral solutions in large volume parenteral containers for intravenous administration to a patient. In an embodiment, this system comprises an empty large volume container (210) including at least one port (224) for accessing an interior (216) of the container (210). The port includes a sterilizing filter (228) for sterilizing a fluid fed through the port (224) into the container (210). A second container (250) is provided including a solute (252) and having means for coupling (254) the second container (250) to the large volume container (210) and thereby providing fluid communication therebetween allowing the solute (252) to be received within the interior (216) of the container (210). A sterile water source (230) is also provided including means (256) for placing the sterile water source (230) in fluid communication with the port (224) and allowing water to flow from the sterile water source (230) into the interior (216) of the container (210). This allows the solute (252) and sterile water that has been fed through the filter (228) to create a parenteral solution in the large volume parenteral container (210).
摘要翻译：本发明提供了一种用于在远离无菌环境的现场创建的系统和方法，用于向患者静脉内施用的大体积肠胃外容器中的肠胃外溶液。在一个实施例中，该系统包括空的大容积容器（210），其包括用于进入容器（210）的内部（216）的至少一个端口（224）。所述端口包括消毒过滤器（228），用于对通过所述端口（224）供入到所述容器（210）中的流体进行消毒。提供了第二容器（250），其包括溶质（252）并且具有用于将第二容器（250）联接（254）到大体积容器（210）的装置，从而在其间提供流体连通，允许溶质（252）容纳在容器（210）的内部（216）内。还提供无菌水源（230），其包括用于将无菌水源（230）与端口（224）流体连通并使水从无菌水源（230）流入内部的装置（256） 216）。这允许已经通过过滤器（228）进料的溶质（252）和无菌水在大容积肠胃外容器（210）中产生肠胃外溶液。

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