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1. 发明申请

WO2013009797A1 OSMOTIC BIOELECTROCHEMICAL SYSTEMS 审中-公开
公开(公告)号：WO2013009797A1
公开(公告)日：2013-01-17
申请号：PCT/US2012/046151
申请日：2012-07-11
申请人： UWM RESEARCH FOUNDATION, INC. , HE, Zhen
发明人： HE, Zhen
IPC分类号： C02F9/14 , C02F1/44
CPC分类号： B01D61/002 , B01D61/025 , B01D2311/25 , C02F1/441 , C02F1/445 , C02F3/005 , C02F3/341 , C02F2001/46138 , C02F2103/08 , C02F2201/003 , C02F2201/46115 , C02F2301/024 , C02F2301/08 , C02F2303/10 , C02F2303/16 , Y02A20/131 , Y02W10/30
摘要： A bioelectrochemical system includes an anode, a saline solution chamber, and a cathode. The anode is at least partially positioned within an anode chamber containing an aqueous reaction mixture including one or more organic compounds and one or more bacteria for oxidizing the organic compounds. The saline solution chamber contains a draw solution and is separated from the anode chamber by a forward osmosis membrane. Water diffuses across the forward osmosis membrane from the aqueous reaction mixture to the draw solution.
摘要翻译：生物电化学系统包括阳极，盐水溶液室和阴极。阳极至少部分地位于包含含有一种或多种有机化合物和一种或多种用于氧化有机化合物的细菌的含水反应混合物的阳极室内。盐水溶液室含有一个拉伸溶液，并通过正向渗透膜与阳极室分离。水从正反渗透膜从水性反应混合物扩散到拉伸溶液。

2. 发明申请

WO2010088626A3 ELECTRICITY GENERATION USING PHOTOTROPHIC MICROBIAL FUEL CELLS 审中-公开
公开(公告)号：WO2010088626A3
公开(公告)日：2010-08-05
申请号：PCT/US2010/022773
申请日：2010-02-01
申请人： UNIVERSITY OF SOUTHERN CALIFORNIA , NEALSON, Kenneth, H. , HE, Zhen
发明人： NEALSON, Kenneth, H. , HE, Zhen
IPC分类号： H01M8/16 , C12N7/00 , A01K61/00 , C10L1/08
摘要： A sediment-type self-sustained phototrophic microbial fuel cell (100) for generating electricity through the syntrophic interaction between photo synthetic microorganisms and heterotrophic bacteria in algae cultivation ponds (102) used for biodiesel production. The microbial fuel cell is operable to continuously produce electricity without the external input of exogenous organics or nutrients.

3. 发明申请

WO2010088626A2 ELECTRICITY GENERATION USING PHOTOTROPHIC MICROBIAL FUEL CELLS 审中-公开
标题翻译：使用光电微生物燃料电池进行电力生成
公开(公告)号：WO2010088626A2
公开(公告)日：2010-08-05
申请号：PCT/US2010022773
申请日：2010-02-01
申请人： UNIV SOUTHERN CALIFORNIA , NEALSON KENNETH H , HE ZHEN
发明人： NEALSON KENNETH H , HE ZHEN
IPC分类号： H01M8/16 , A01K61/00 , C10L1/08 , C12N7/00
CPC分类号： H01M8/16 , Y02E60/527 , Y02P70/56
摘要： A sediment-type self-sustained phototrophic microbial fuel cell (100) for generating electricity through the syntrophic interaction between photo synthetic microorganisms and heterotrophic bacteria in algae cultivation ponds (102) used for biodiesel production The microbial fuel cell is operable to continuously produce electricity without the external input of exogenous organics or nutrients
摘要翻译：用于生物柴油生产的藻类养殖池（102）中通过光合成微生物和异养细菌之间的合成相互作用产生电力的沉积物型自持式光养性微生物燃料电池（100）微生物燃料电池可操作以连续发电而无需外源有机物或营养素的外部投入

4. 发明申请

WO2005077954A3 PYRAZOLOPYRIMIDINE-DERIVATIVES AS CYCLIN DEPENDENT KINASE INHIBITORS 审中-公开
标题翻译：作为CYCLIN依赖性激酶抑制剂的吡唑并嘧啶衍生物
公开(公告)号：WO2005077954A3
公开(公告)日：2005-10-13
申请号：PCT/US2005003859
申请日：2005-02-08
申请人： SCHERING CORP , PHARMACOPEIA DRUG DISCOVERY , GUZI TIMOTHY J , PARUCH KAMIL , DWYER MICHAEL P , DOLL RONALD J , GIRIJAVALLABHAN VIYYOOR MOOPIL , MALLAMS ALAN , ALVAREZ CARMEN S , KEERTIKAR KARTIK M , RIVERA JOCELYN , CHAN TIN-YAU , MADISON VINCENT , FISCHMANN THIERRY O , DILLARD LAWRENCE W , TRAN VINH D , HE ZHEN MIN , JAMES RAY ANTHONY , PARK HAENGSOON , PARADKAR VIDYADHAR M , HOBBS DOUGLAS WALSH
发明人： GUZI TIMOTHY J , PARUCH KAMIL , DWYER MICHAEL P , DOLL RONALD J , GIRIJAVALLABHAN VIYYOOR MOOPIL , MALLAMS ALAN , ALVAREZ CARMEN S , KEERTIKAR KARTIK M , RIVERA JOCELYN , CHAN TIN-YAU , MADISON VINCENT , FISCHMANN THIERRY O , DILLARD LAWRENCE W , TRAN VINH D , HE ZHEN MIN , JAMES RAY ANTHONY , PARK HAENGSOON , PARADKAR VIDYADHAR M , HOBBS DOUGLAS WALSH
IPC分类号： A61K31/495 , C07D487/04 , A61P35/00
CPC分类号： C07D487/04 , A61K31/495
摘要： In its many embodiments, the present invention provides pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
摘要翻译：在其许多实施方案中，本发明提供了作为细胞周期蛋白依赖性激酶抑制剂的吡唑并[1,5-a]嘧啶化合物，制备此类化合物的方法，含有一种或多种此类化合物的药物组合物，制备包含一种或多种这些化合物，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与CDK相关的一种或多种疾病的方法。

5. 发明申请

WO2005077954A2 NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS 审中-公开
标题翻译：作为CYCLIN依赖性激酶抑制剂的吡唑并嘧啶衍生物
公开(公告)号：WO2005077954A2
公开(公告)日：2005-08-25
申请号：PCT/US2005/003859
申请日：2005-02-08
申请人： SCHERING CORPORATION , PHARMACOPEIA DRUG DISCOVERY, INC. , GUZI, Timothy J. , PARUCH, Kamil , DWYER, Michael P. , DOLL, Ronald J. , GIRIJAVALLABHAN, Viyyoor Moopil , MALLAMS, Alan , ALVAREZ, Carmen S. , KEERTIKAR, Kartik M. , RIVERA, Jocelyn , CHAN, Tin-Yau , MADISON, Vincent , FISCHMANN, Thierry O. , DILLARD, Lawrence W. , TRAN, Vinh D. , HE, Zhen Min , JAMES, Ray Anthony , PARK, Haengsoon , PARADKAR, Vidyadhar M. , HOBBS, Douglas Walsh
发明人： GUZI, Timothy J. , PARUCH, Kamil , DWYER, Michael P. , DOLL, Ronald J. , GIRIJAVALLABHAN, Viyyoor Moopil , MALLAMS, Alan , ALVAREZ, Carmen S. , KEERTIKAR, Kartik M. , RIVERA, Jocelyn , CHAN, Tin-Yau , MADISON, Vincent , FISCHMANN, Thierry O. , DILLARD, Lawrence W. , TRAN, Vinh D. , HE, Zhen Min , JAMES, Ray Anthony , PARK, Haengsoon , PARADKAR, Vidyadhar M. , HOBBS, Douglas Walsh
IPC分类号： C07D487/04
CPC分类号： C07D487/04 , A61K31/495
摘要： In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]pyrimidine compounds as inhibitors of cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or more such compounds, methods of preparing pharmaceutical formulations comprising one or more such compounds, and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with the CDKs using such compounds or pharmaceutical compositions.
摘要翻译：在其许多实施方案中，本发明提供了作为细胞周期蛋白依赖性激酶抑制剂的吡唑并[1,5-a]嘧啶化合物，制备此类化合物的方法，含有一种或多种此类化合物的药物组合物，制备包含一种或多种这些化合物，以及使用这些化合物或药物组合物治疗，预防，抑制或改善与CDK相关的一种或多种疾病的方法。

6. 发明申请

WO2003000479A2 TRANSFER MOLDING MACHINE WITH FEATURES FOR ENHANCED CULL REMOVAL 审中-公开
标题翻译：转移成型机具有增强型除头功能
公开(公告)号：WO2003000479A2
公开(公告)日：2003-01-03
申请号：PCT/SG2002/000127
申请日：2002-06-21
申请人： ADVANCED SYSTEMS AUTOMATION LTD , HE, Zhen Hua , ROSLAN BIN, Ismail , WANG, Zi Yao
发明人： HE, Zhen Hua , ROSLAN BIN, Ismail , WANG, Zi Yao
IPC分类号： B29C
CPC分类号： B29C45/38 , B29C45/02
摘要： A transfer molding machine (10) with an injection mold plate (12). The injection mold plate has ejection pins (22,24) for ejecting a cull in a first direction (40). Each of the ejection pins (22,24) has a sprue abutment (50) with a notch (52). The notch is oriented to enable dislodging of the cull in a second direction (54), substantially normal to the first direction (40) and away from the sprue abutment (50). A method (100) for cull removal by transfer molding machine (10) upon curing a molding ends with the cull being moved out of the transfer molding machine (10) using a movable bar (200) with stubs (202).
摘要翻译：具有注塑模板（12）的传递模塑机（10）。注射模板具有用于沿第一方向（40）排出剔除物的排出销（22,24）。每个顶出销（22,24）具有带有凹口（52）的浇道基台（50）。切口定向成能够使第二方向54基本上垂直于第一方向40并且远离浇道基牙50移动剔除。一种用于在传送模制机（10）固化模制品时用于通过传送模制机（10）使用具有短柱（202）的可移动杆（200）将剔除物从传送模制机（10）移出的方法（100） >

7. 发明申请

WO1998020350A1 COMBINATORIAL HYDROXY-AMINO ACID AMIDE LIBRARIES 审中-公开
标题翻译：组合羟基氨基酸酰胺类化合物
公开(公告)号：WO1998020350A1
公开(公告)日：1998-05-14
申请号：PCT/US1997020305
申请日：1997-11-04
申请人： PHARMACOPEIA, INC. , DOLLE, Rolland, Ellwood, III , GUO, Tao , JOHNSON, Theodore, Otto, Jr. , PATEL, Hitesh, K. , TAO, Shiwei , HE, Zhen, Min
发明人： PHARMACOPEIA, INC.
IPC分类号： G01N33/53
CPC分类号： C07D207/14 , C07D207/16 , C07D241/04
摘要： Combinatorial chemical libraries of Formula (I) and methods for their preparation are disclosed. The libraries allow one to screen large numbers of compounds for a desired biological activity with relative ease. The libraries may be tagged or untagged. In preferred libraries, Y is the residue of an N-acylated amino acid, a substituted 4-aminoproline or a substituted piperazinealkanoic acid. The use of the libraries to discover biologically active compounds is also disclosed.
摘要翻译：公开了式（I）的组合化学文库及其制备方法。这些文库允许相对容易地筛选大量化合物以获得所需的生物活性。库可能被标记或未标记。在优选的文库中，Y是N-酰化氨基酸，取代的4-氨基脯氨酸或取代的哌嗪烷酸的残基。还公开了使用这些文库发现生物活性化合物。

8. 发明申请

WO2009140428A1 ELECTRICITY GENERATION USING MICROBIAL FUEL CELLS 审中-公开
标题翻译：使用微生物燃料电池的电力生成
公开(公告)号：WO2009140428A1
公开(公告)日：2009-11-19
申请号：PCT/US2009/043848
申请日：2009-05-13
申请人： UNIVERSITY OF SOUTHERN CALIFORNIA USC STEVENS , HE, Zhen , NEALSON, Kenneth, H. , MANSFELD, Florian
发明人： HE, Zhen , NEALSON, Kenneth, H. , MANSFELD, Florian
IPC分类号： H01M8/16
CPC分类号： H01M8/16 , C02F1/46104 , C02F3/301 , C02F3/302 , C02F3/341 , C02F2001/46123 , C02F2101/16 , C02F2101/163 , C02F2101/166 , Y02E60/527
摘要： A microbial fuel cell for generating electricity. The microbial fuel cell includes an anode and a cathode electrically coupled to the anode. The anode is in contact with a first fluid including microorganisms capable of catalyzing the oxidation of ammonium. The cathode is in contact with a second fluid including microorganisms capable of catalyzing the reduction of nitrite The anode and the cathode may be housed in a single compartment, and the cathode may rotate with respect to the anode. The microbial fuel cell can be used to remove ammonium from wastewater, to generate electricity, or both.
摘要翻译：一种用于发电的微生物燃料电池。微生物燃料电池包括电耦合到阳极的阳极和阴极。阳极与包含能够催化铵氧化的微生物的第一流体接触。阴极与包括能够催化亚硝酸盐还原的微生物的第二流体接触。阳极和阴极可以容纳在单个隔室中，并且阴极可以相对于阳极旋转。微生物燃料电池可用于从废水中除去铵，产生电力，或两者兼而有之。

9. 发明申请

WO2009140428A8 ELECTRICITY GENERATION USING MICROBIAL FUEL CELLS 审中-公开
标题翻译：使用微生物燃料电池的电力生成
公开(公告)号：WO2009140428A8
公开(公告)日：2011-01-27
申请号：PCT/US2009043848
申请日：2009-05-13
申请人： UNIV SOUTHERN CALIFORNIA , HE ZHEN , NEALSON KENNETH H , MANSFELD FLORIAN
发明人： HE ZHEN , NEALSON KENNETH H , MANSFELD FLORIAN
IPC分类号： H01M8/16
CPC分类号： H01M8/16 , C02F1/46104 , C02F3/301 , C02F3/302 , C02F3/341 , C02F2001/46123 , C02F2101/16 , C02F2101/163 , C02F2101/166 , Y02E60/527
摘要： A microbial fuel cell for generating electricity. The microbial fuel cell includes an anode and a cathode electrically coupled to the anode. The anode is in contact with a first fluid including microorganisms capable of catalyzing the oxidation of ammonium. The cathode is in contact with a second fluid including microorganisms capable of catalyzing the reduction of nitrite The anode and the cathode may be housed in a single compartment, and the cathode may rotate with respect to the anode. The microbial fuel cell can be used to remove ammonium from wastewater, to generate electricity, or both.
摘要翻译：用于发电的微生物燃料电池。微生物燃料电池包括电耦合到阳极的阳极和阴极。阳极与包含能够催化铵氧化的微生物的第一流体接触。阴极与包括能够催化还原亚硝酸盐的微生物的第二流体接触。阳极和阴极可以容纳在单个隔室中，并且阴极可以相对于阳极旋转。微生物燃料电池可用于从废水中除去铵，产生电力或两者。

10. 发明申请

WO2006072112A1 UPFLOW MICROBIAL FUEL CELL (UMFC) 审中-公开
标题翻译： UPFLOW微型燃料电池（UMFC）
公开(公告)号：WO2006072112A1
公开(公告)日：2006-07-06
申请号：PCT/US2005/047697
申请日：2005-12-30
申请人： WASHINGTON UNIVERSITY , ANGENENT, Largus, Theodora , HE, Zhen
发明人： ANGENENT, Largus, Theodora , HE, Zhen
IPC分类号： H01M8/16
CPC分类号： H01M8/16 , C02F3/305 , H01M4/90 , Y02E60/527
摘要： An upflow microbial fuel cell in one embodiment is comprised of a generally cylindrical cathode chamber containing a cathode sitting atop a generally cylindrical anode chamber containing an anode, with a proton exchange membrane separating the two chambers, so that as influent is passed upwardly through the anode chamber electricity is created in a continuous process not requiring mixing such as with a mechanical mixer or the like. Electrodes are connected to each of the anode and the cathode for harvesting the electricity so created. Effluent may be recirculated through the anode chamber by a second inlet and outlet therein. A multiphase fuel cell includes a plurality of electrode couples arranged in a single chamber with an influent inlet near its bottom and an effluent outlet near its top, with the electrode couples connected in series to generate electricity at higher voltages. In another embodiment, the cathode chamber - preferably U-shaped - is positioned inside the anode chamber.
摘要翻译：在一个实施例中，向上流动的微生物燃料电池由通常为圆柱形的阴极室组成，其中阴极位于包含阳极的大致圆柱形的阳极室顶部，质子交换膜分离两个室，使得当流体向上通过阳极室内电力以不需要混合的连续过程如机械混合器等产生。电极连接到阳极和阴极中的每一个，以收集如此产生的电力。流出物可以通过其中的第二入口和出口通过阳极室再循环。多相燃料电池包括布置在单个室中的多个电极对，其底部附近的流入物入口和其顶部附近的流出物出口，电极对串联连接以在较高电压下发电。在另一个实施例中，阴极室 - 优选为U形 - 位于阳极室内。

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