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1. 发明申请

WO2007103258A3 FLEXIBLE SLEEVE FOR CATHETER 审中-公开
标题翻译：柔性套管
公开(公告)号：WO2007103258A3
公开(公告)日：2008-02-07
申请号：PCT/US2007005508
申请日：2007-03-05
申请人： BOSTON SCIENT SCIMED INC , ESKURI ALAN D , JOHNSON CHRISTOPHER , HARRIS CHAD , HAWK MATTHEW L , KIM GRACE
发明人： ESKURI ALAN D , JOHNSON CHRISTOPHER , HARRIS CHAD , HAWK MATTHEW L , KIM GRACE
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61M25/0045 , A61M25/0069 , A61M25/0084 , A61M25/0138
摘要： A catheter is provided for the injection of therapeutic agents at a target site within a patient's body. The catheter includes a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also includes a second elongated shaft in the form of a needle slidingly disposed in the first elongated shaft, the needle having a distal end and a proximal and a lumen extending therebetween. The catheter may include a flexible sleeve, wherein the flexible sleeve compresses along the inside of a curve and elongates along the outside of a curve. The catheter may additionally or alternatively include an adjustable distal tissue contact surface, wherein the position of the distal tissue contact surface may be adjusted with respect to a stop surface for stopping the advancement of a needle. The catheter may additionally or alternatively include a fluid pressure contact monitor.
摘要翻译：提供了用于在患者体内的靶位置处注射治疗剂的导管。导管包括具有远端和近端的第一细长轴和在其间延伸的内腔。导管还包括滑动地设置在第一细长轴中的针形式的第二细长轴，所述针具有远端和近端以及在其间延伸的内腔。导管可以包括柔性套管，其中柔性套筒沿曲线的内部压缩并且沿着曲线的外侧延伸。导管可另外地或可选地包括可调节的远端组织接触表面，其中远侧组织接触表面的位置可以相对于止动表面进行调整，以阻止针的前进。导管可以附加地或替代地包括流体压力接触监视器。

2. 发明申请

WO2007103258A2 FLEXIBLE SLEEVE, ADJUSTABLE CONTACT SURFACE, AND FLUID CONTACT MONITOR FOR CATHETER 审中-公开
标题翻译：柔性套筒，可调节的接触表面和流体接触式监视器
公开(公告)号：WO2007103258A2
公开(公告)日：2007-09-13
申请号：PCT/US2007/005508
申请日：2007-03-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ESKURI, Alan, D. , JOHNSON, Christopher , HARRIS, Chad , HAWK, Matthew, L. , KIM, Grace
发明人： ESKURI, Alan, D. , JOHNSON, Christopher , HARRIS, Chad , HAWK, Matthew, L. , KIM, Grace
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61M25/0045 , A61M25/0069 , A61M25/0084 , A61M25/0138
摘要： A catheter is provided for the injection of therapeutic agents at a target site within a patient's body. The catheter includes a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also includes a second elongated shaft in the form of a needle slidingly disposed in the first elongated shaft, the needle having a distal end and a proximal and a lumen extending therebetween. The catheter may include a flexible sleeve, wherein the flexible sleeve compresses along the inside of a curve and elongates along the outside of a curve. The catheter may additionally or alternatively include an adjustable distal tissue contact surface, wherein the position of the distal tissue contact surface may be adjusted with respect to a stop surface for stopping the advancement of a needle. The catheter may additionally or alternatively include a fluid pressure contact monitor.
摘要翻译：提供导管，用于在患者体内的靶位置处注射治疗剂。导管包括第一细长轴，其具有远端和近端以及在其间延伸的内腔。导管还包括滑动地设置在第一细长轴中的针形式的第二细长轴，所述针具有远端和近端以及在其间延伸的内腔。导管可以包括柔性套管，其中柔性套筒沿着曲线的内部压缩并沿着曲线的外侧延伸。导管可另外地或替代地包括可调节的远端组织接触表面，其中远端组织接触表面的位置可以相对于止动表面进行调整，以阻止针的前进。导管可以附加地或可选地包括流体压力接触监视器。

3. 发明申请

WO2005082443A3 VARIABLE DEPTH INJECTION DEVICE 审中-公开
标题翻译：可变深度注射装置
公开(公告)号：WO2005082443A3
公开(公告)日：2005-12-15
申请号：PCT/US2005004175
申请日：2005-02-20
申请人： BOSTON SCIENT SCIMED INC , HARRIS CHAD G , HAWK MATTHEW L , MICKLEY TIMOTHY J
发明人： HARRIS CHAD G , HAWK MATTHEW L , MICKLEY TIMOTHY J
IPC分类号： A61M25/00 , A61M25/01 , A61M25/06
CPC分类号： A61M25/0606 , A61M25/0068 , A61M25/0069 , A61M25/0084 , A61M2025/0089
摘要： An apparatus for the injection of therapeutic and other agents at a target site within a patient's body. A catheter including a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also including a second elongated shaft slidingly disposed in the first elongated shaft, the second elongated shaft having a distal end and a proximal and a lumen extending therebetween. The catheter further including a third elongated shaft disposed in and attached to the second elongate shaft, the third elongated shaft to move in a one-to-one relationship with the first elongated shaft and the second elongated shaft to maintain a predetermined needle deployment length as each are subjected to various bend configurations.
摘要翻译：用于在患者体内的靶位置注射治疗剂和其它药剂的装置。一种导管，其包括具有远端和近端的第一细长轴和在其间延伸的内腔。导管还包括滑动地设置在第一细长轴中的第二细长轴，第二细长轴具有远端和近端以及在其间延伸的内腔。所述导管还包括设置在所述第二细长轴中并连接到所述第二细长轴的第三细长轴，所述第三细长轴与所述第一细长轴和所述第二细长轴以一对一关系移动，以将预定的针展开长度保持为每个都经受各种弯曲构造。

4. 发明申请

WO2006083646A3 NON-CORING NEEDLES AND METHODS OF MANUFACTURING SAME 审中-公开
标题翻译：非牙齿针及其制造方法
公开(公告)号：WO2006083646A3
公开(公告)日：2007-01-11
申请号：PCT/US2006002607
申请日：2006-01-25
申请人： BOSTON SCIENT SCIMED INC , HARRIS CHAD G , HAWK MATTHEW , ROONEY JACOB , SMITH MARK S , OSTROOT TIMOTHY A
发明人： HARRIS CHAD G , HAWK MATTHEW , ROONEY JACOB , SMITH MARK S , OSTROOT TIMOTHY A
IPC分类号： A61M5/32 , A61J1/00
CPC分类号： A61M5/3286 , A61J1/201 , A61J1/2096 , A61J2200/10 , A61M2205/195
摘要： Needles (10, 200, 300, 400, 500, 600) configured to prevent or reduce contact of tissue or other material with the heel (80) of the needle to prevent coring of the tissue or other material by the heel of the needle. Also provided are needles having no heels or blunted heels. The prevent invention also provides methods of manufacturing needles having obstructed or blunted heels.
摘要翻译：被配置为防止或减少组织或其他材料与针的跟部（80）的接触的针（10,200,300,400,500,600），以防止针的跟部使组织或其他材料的取芯。还提供了没有高跟或钝的高跟鞋的针。防止发明还提供了制造具有阻塞或钝的高跟鞋的针的方法。

5. 发明申请

WO2005082443A2 VARIABLE DEPTH INJECTION DEVICE AND METHOD 审中-公开
标题翻译：可变深度注射装置和方法
公开(公告)号：WO2005082443A2
公开(公告)日：2005-09-09
申请号：PCT/US2005/004175
申请日：2005-02-20
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HARRIS, Chad, G. , HAWK, Matthew, L. , MICKLEY, Timothy, J.
发明人： HARRIS, Chad, G. , HAWK, Matthew, L. , MICKLEY, Timothy, J.
IPC分类号： A61M25/00
CPC分类号： A61M25/0606 , A61M25/0068 , A61M25/0069 , A61M25/0084 , A61M2025/0089
摘要： An apparatus for the injection of therapeutic and other agents at a target site within a patient's body. A catheter including a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also including a second elongated shaft slidingly disposed in the first elongated shaft, the second elongated shaft having a distal end and a proximal and a lumen extending therebetween. The catheter further including a third elongated shaft disposed in and attached to the second elongate shaft, the third elongated shaft to move in a one-to-one relationship with the first elongated shaft and the second elongated shaft to maintain a predetermined needle deployment length as each are subjected to various bend configurations.
摘要翻译：用于在患者体内的靶位置注射治疗剂和其它药剂的装置。一种导管，其包括具有远端和近端的第一细长轴和在其间延伸的内腔。导管还包括滑动地设置在第一细长轴中的第二细长轴，第二细长轴具有远端和近端以及在其间延伸的内腔。所述导管还包括设置在所述第二细长轴中并连接到所述第二细长轴的第三细长轴，所述第三细长轴与所述第一细长轴和所述第二细长轴以一对一关系移动，以将预定的针展开长度保持为每个都经受各种弯曲构造。

6. 发明申请

WO2007103258A9 FLEXIBLE SLEEVE, ADJUSTABLE CONTACT SURFACE, AND FLUID CONTACT MONITOR FOR CATHETER 审中-公开
标题翻译：柔性套管，可调节的接触表面和导管的流体接触监测器
公开(公告)号：WO2007103258A9
公开(公告)日：2007-12-21
申请号：PCT/US2007005508
申请日：2007-03-05
申请人： BOSTON SCIENT SCIMED INC , ESKURI ALAN D , JOHNSON CHRISTOPHER , HARRIS CHAD , HAWK MATTHEW L , KIM GRACE
发明人： ESKURI ALAN D , JOHNSON CHRISTOPHER , HARRIS CHAD , HAWK MATTHEW L , KIM GRACE
IPC分类号： A61M25/00
CPC分类号： A61M25/0054 , A61M25/0045 , A61M25/0069 , A61M25/0084 , A61M25/0138
摘要： A catheter is provided for the injection of therapeutic agents at a target site within a patient's body. The catheter includes a first elongated shaft having a distal end and a proximal end and a lumen extending therebetween. The catheter also includes a second elongated shaft in the form of a needle slidingly disposed in the first elongated shaft, the needle having a distal end and a proximal and a lumen extending therebetween. The catheter may include a flexible sleeve, wherein the flexible sleeve compresses along the inside of a curve and elongates along the outside of a curve. The catheter may additionally or alternatively include an adjustable distal tissue contact surface, wherein the position of the distal tissue contact surface may be adjusted with respect to a stop surface for stopping the advancement of a needle. The catheter may additionally or alternatively include a fluid pressure contact monitor.
摘要翻译：提供导管用于在患者体内的目标部位注射治疗剂。导管包括具有远端和近端以及在其间延伸的内腔的第一细长轴。导管还包括以滑动方式设置在第一细长轴中的针形式的第二细长轴，该针具有远端和近端以及在其间延伸的内腔。导管可以包括柔性套管，其中柔性套管沿曲线的内侧压缩并且沿曲线的外侧延伸。导管可以附加地或可选地包括可调节远侧组织接触表面，其中远侧组织接触表面的位置可以相对于用于停止针前进的止动表面进行调节。导管可以附加地或可选地包括流体压力接触监测器。

7. 发明申请

WO2005094933A2 CATHETER WITH SENSOR TIPS, TOOL AND DEVICE AND METHODS OF USE OF SAME 审中-公开
标题翻译：带传感器提示的导管，工具和装置及其使用方法
公开(公告)号：WO2005094933A2
公开(公告)日：2005-10-13
申请号：PCT/US2005009788
申请日：2005-03-23
申请人： BOSTON SCIENT SCIMED INC , HARRIS CHAD G , HAWK MATTHEW L , MICKLEY TIMOTHY J , PANESCU DORIN , PALASIS MARIA , ROONEY JACOB
发明人： HARRIS CHAD G , HAWK MATTHEW L , MICKLEY TIMOTHY J , PANESCU DORIN , PALASIS MARIA , ROONEY JACOB
IPC分类号： A61B5/0408 , A61B5/042 , A61M25/00
CPC分类号： A61B5/4839 , A61B5/0422 , A61B5/0538 , A61B5/6885 , A61M25/0084
摘要： An apparatus and method for catheter-based sensing and injection at a target site within a patient's body. An injection catheter is equipped with a electrodes at its distal end which contact the surface of a target site, such as an AV node of the heart. Electrical signals detected at the target site by the electrodes are fed via leads to the proximal end of the catheter, where they are received by a monitor, such as an EKG monitor. If the electrical signals satisfy predetermined criteria, a needle within the catheter is extended into the target site, and a therapeutic agent is injected into the target site.
摘要翻译：一种用于基于导管的感测和注射在患者体内的靶位置的装置和方法。注射导管在其远端配备有电极，其接触目标部位的表面，例如心脏的AV节点。通过电极在目标部位检测到的电信号通过引线馈送到导管的近端，在那里它们被诸如EKG监视器的监视器接收。如果电信号满足预定标准，则导管内的针头延伸到目标部位，并将治疗剂注射到目标部位。

8. 发明申请

WO2006083646A2 NON-CORING NEEDLES AND METHODS OF MANUFACTURING SAME 审中-公开
标题翻译：非牙齿针及其制造方法
公开(公告)号：WO2006083646A2
公开(公告)日：2006-08-10
申请号：PCT/US2006/002607
申请日：2006-01-25
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HARRIS, Chad, G. , HAWK, Matthew , ROONEY, Jacob , SMITH, Mark, S. , OSTROOT, Timothy, A.
发明人： HARRIS, Chad, G. , HAWK, Matthew , ROONEY, Jacob , SMITH, Mark, S. , OSTROOT, Timothy, A.
IPC分类号： A61M5/32 , A61J1/00
CPC分类号： A61M5/3286 , A61J1/201 , A61J1/2096 , A61J2200/10 , A61M2205/195
摘要： Needles configured to prevent or reduce contact of tissue or other material with the heel of the needle to prevent coring of the tissue or other material by the heel of the needle. Also provided are needles having no heels or blunted heels. The prevent invention also provides methods of manufacturing needles having obstructed or blunted heels.
摘要翻译：针被配置为防止或减少组织或其他材料与针的跟部的接触，以防止针的跟部使组织或其他材料的取芯。还提供了没有高跟或钝的高跟鞋的针。防止发明还提供了制造具有阻塞或钝的高跟鞋的针的方法。

9. 发明申请

WO2005094933A3 CATHETER WITH SENSOR TIPS, TOOL AND DEVICE AND METHODS OF USE OF SAME 审中-公开
公开(公告)号：WO2005094933A3
公开(公告)日：2005-10-13
申请号：PCT/US2005/009788
申请日：2005-03-23
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HARRIS, Chad, G. , HAWK, Matthew, L. , MICKLEY, Timothy, J. , PANESCU, Dorin , PALASIS, Maria , ROONEY, Jacob
发明人： HARRIS, Chad, G. , HAWK, Matthew, L. , MICKLEY, Timothy, J. , PANESCU, Dorin , PALASIS, Maria , ROONEY, Jacob
IPC分类号： A61M25/00
摘要： An apparatus and method for catheter-based sensing and injection at a target site within a patient's body. An injection catheter is equipped with electrodes (1410, 1420) at its distal end which contact the surface of a target site, such as an AV node of the heart. Electrical signals detected at the target site by the electrodes (1410, 1420) are fed via leads (1460, 1465) to the proximal end of the catheter, where they are received by a monitor, such as an EKG monitor. If the electrical signals satisfy predetermined criteria, a needle within the catheter is extended into the target site, and a therapeutic agent is injected into the target site.

10. 发明申请

WO2005092184A1 CATHETER WITH ELECTRODE SENSOR TIP AND RECIPROCATABLE INJECTION NEEDLE 审中-公开
标题翻译：带电极传感器提针和可重复注射针的导管
公开(公告)号：WO2005092184A1
公开(公告)日：2005-10-06
申请号：PCT/US2005/010003
申请日：2005-03-23
申请人： BOSTON SCIENTIFIC SCIMED, INC. , HARRIS, Chad, G. , HAWK, Matthew, L. , MICKLEY, Timothy, J. , PANESCU, Dorin , PALASIS, Maria , ROONEY, Jacob
发明人： HARRIS, Chad, G. , HAWK, Matthew, L. , MICKLEY, Timothy, J. , PANESCU, Dorin , PALASIS, Maria , ROONEY, Jacob
IPC分类号： A61B5/042
CPC分类号： A61B5/0422 , A61B5/6852 , A61B2018/00875 , A61B2018/1425 , A61B2218/002 , A61M25/0084 , A61M25/0136 , A61M2025/0096 , A61N1/0568
摘要： An apparatus and method for catheter-based sensing and injection at a target site within a patient's body. An injection catheter is equipped with electrodes (1012, 1022) at its distal end which contact the surface of a target site, such as an AV node of the heart. Electrical signals detected at the target site by the electrodes are fed via leads (1014, 1024) to the proximal end of the catheter, where they are received by a monitor such as an EKG monitor. If the electrical signals satisfy predetermined criteria, a needle (1050) within the catheter is extended into the target site, and a therapeutic agent is injected into the target site.
摘要翻译：一种用于在患者体内的目标部位进行基于导管的感测和注射的装置和方法。注射导管在其远端配备有电极（1012,1022），其接触目标部位的表面，例如心脏的AV节点。通过电极在目标部位检测到的电信号通过引线（1014,1024）馈送到导管的近端，在那里它们被诸如EKG监视器的监视器接收。如果电信号满足预定的标准，则导管内的针（1050）延伸到目标部位，并将治疗剂注入目标部位。

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