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1. 发明申请

WO2015192046A1 SYSTEM FOR FAST ULTRASOUND TREATMENT 审中-公开
标题翻译：快速超声治疗系统
公开(公告)号：WO2015192046A1
公开(公告)日：2015-12-17
申请号：PCT/US2015/035615
申请日：2015-06-12
申请人： GUIDED THERAPY SYSTEMS, LLC
发明人： BARTHE, Peter, G. , SLAYTON, Michael, H.
IPC分类号： A61N7/00
CPC分类号： A61N7/00 , A61B18/1815 , A61B18/203 , A61B2017/00075 , A61B2017/00106 , A61B2017/00119 , A61B2017/00128 , A61B2018/00452 , A61B2018/00648 , A61B2018/0066 , A61B2018/00672 , A61B2018/00678 , A61B2018/00708 , A61B2018/00791 , A61B2018/00875 , A61B2018/00994 , A61B2018/1807 , A61B2018/1876 , A61B2090/064 , A61B2090/065 , A61N7/02 , A61N2007/0034 , A61N2007/0065 , A61N2007/0078 , A61N2007/0082
摘要： This disclosure provides systems and methods for fast ultrasound treatment. The systems and methods can involve a treatment device including a housing, a transducer module, and a control module. Energy emitted from an energy source of the treatment device can pass through an acoustic window having a non-zero radius of curvature. The treatment device can be moved along a target surface while retaining contact between the acoustic window and the target surface. Coupling between the energy source and a region of interest can be retained upon a change in an angle of incidence of the energy relative to the target surface.
摘要翻译：本公开提供用于快速超声治疗的系统和方法。该系统和方法可涉及包括壳体，换能器模块和控制模块的处理装置。从治疗装置的能源发射的能量可以通过具有非零曲率半径的声窗口。治疗装置可以沿着目标表面移动，同时保持声窗和目标表面之间的接触。能量源和感兴趣区域之间的耦合可以在能量相对于目标表面的入射角的变化时保持。

2. 发明申请

WO2013009787A3 METHODS AND SYSTEMS FOR ULTRASOUND TREATMENT 审中-公开
标题翻译：超声治疗方法与系统
公开(公告)号：WO2013009787A3
公开(公告)日：2013-04-18
申请号：PCT/US2012046125
申请日：2012-07-10
申请人： GUIDED THERAPY SYSTEMS LLC , BARTHE PETER G
发明人： BARTHE PETER G
IPC分类号： A61N7/00 , A61B18/04 , A61B18/18 , A61N5/10
CPC分类号： A61N7/00 , A61B18/18 , A61B2018/00642 , A61M37/0092 , A61N7/02 , A61N2007/0004 , A61N2007/0017 , A61N2007/0034 , A61N2007/0039 , A61N2007/0052 , A61N2007/006 , A61N2007/0073 , A61N2007/0078 , A61N2007/027
摘要： A method and system for ultrasound treatment are provided. Acoustic energy, including ultrasound, can serve as input energy to a mask with apertures, such apertures acting as secondary acoustic sources to create a modulated output acoustic energy in a treatment region and treatment effects. Under proper control output energy can be precisely placed and controlled in tissue. In some embodiments, methods and systems are configured for ultrasound treatment based on creating an output energy distribution in tissue. In some embodiments, methods and systems are configured based on creating an output temperature distribution in tissue.
摘要翻译：提供了一种超声处理方法和系统。包括超声在内的声能可以作为具有孔的掩模的输入能量，这种孔用作辅助声源，以在处理区域中产生经调制的输出声能和治疗效果。在适当的控制下，输出能量可以精确地放置和控制在组织中。在一些实施例中，基于在组织中产生输出能量分布来配置用于超声治疗的方法和系统。在一些实施例中，基于在组织中产生输出温度分布来配置方法和系统。

3. 发明申请

WO2012018391A3 METHODS AND SYSTEMS FOR TREATING PLANTAR FASCIA 审中-公开
标题翻译：用于治疗植物FASCIA的方法和系统
公开(公告)号：WO2012018391A3
公开(公告)日：2012-07-05
申请号：PCT/US2011001367
申请日：2011-08-02
申请人： GUIDED THERAPY SYSTEMS LLC , SLAYTON MICHAEL H , BARTHE PETER G
发明人： SLAYTON MICHAEL H , BARTHE PETER G
IPC分类号： A61N7/00 , A61B17/54 , A61B18/00
CPC分类号： A61N7/00 , A61B8/13 , A61B8/14 , A61B8/4254 , A61B8/4272 , A61B8/485 , A61B8/5246 , A61B17/320068 , A61B2018/00642 , A61B2018/00898 , A61B2090/378 , A61N7/02 , A61N2007/0013 , A61N2007/0034 , A61N2007/0052 , A61N2007/006 , A61N2007/0065 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Various embodiments, described herein, provide methods and systems for the treatment of plantar fascia. In some embodiments, a method of non-invasive treatment of plantar fasciacan include the steps of identifying a damage location comprising a planter fascia; directing a conformal distribution of ultrasound energy to the plantar fascia at the damage location; creating a plurality of micro lesions in the plantar fascia at the damage location; initiating healing of a plurality of micro tears in the plantar fascia at the damage location; and sparing intervening tissue between the plantar fascia and a surface of a sole of a foot.
摘要翻译：本文所述的各种实施例提供了用于治疗足底筋膜的方法和系统。在一些实施方案中，一种非侵入性治疗足底跖皮的方法包括鉴定包括花坛筋膜的损伤位置的步骤; 将损伤位置处的超声能量的适形分布引导到足底筋膜; 在损伤位置的足底筋膜中产生多个微小损伤; 开始在损伤位置的足底筋膜中的多个微小眼泪的愈合; 并且在足底筋膜和足底的表面之间节省介入组织。

4. 发明申请

WO2012018385A2 SYSTEM AND METHOD FOR TREATING CARTILAGE 审中-公开
标题翻译：用于处理药物的系统和方法
公开(公告)号：WO2012018385A2
公开(公告)日：2012-02-09
申请号：PCT/US2011001361
申请日：2011-08-02
申请人： GUIDED THERAPY SYSTEMS LLC , SLAYTON MICHAEL H , BARTHE PETER G
发明人： SLAYTON MICHAEL H , BARTHE PETER G
IPC分类号： A61B18/00 , A61B1/317 , A61B17/56 , A61B17/94 , A61N7/00
CPC分类号： A61N7/00 , A61B8/13 , A61B8/14 , A61B8/4254 , A61B8/4272 , A61B8/485 , A61B8/5246 , A61B17/320068 , A61B2018/00642 , A61B2018/00898 , A61B2090/378 , A61N7/02 , A61N2007/0013 , A61N2007/0034 , A61N2007/0052 , A61N2007/006 , A61N2007/0065 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Various embodiments provide systems and methods of treating damaged cartilage. In some embodiments, a method can include targeting the damaged cartilage in region of interest, directing therapeutic ultrasound energy to the damaged cartilage, ablating at least a portion of the damaged cartilage and improving the damaged cartilage. The method can include focusing therapeutic ultrasound energy to create at least one lesion in a portion of the damaged cartilage. The method can also include imaging the damaged cartilage. The method can include increasing blood perfusion to the region of interest. The method can include welding together the damaged cartilage with therapeutic ultrasound energy. The method can include cutting the damaged cartilage and removing it from the joint with therapeutic ultrasound energy. The method can include smoothing the cartilage with therapeutic ultrasound energy. The method can include regenerating cartilage.
摘要翻译：各种实施方案提供了治疗受损软骨的系统和方法。在一些实施例中，一种方法可以包括在感兴趣的区域中靶向损伤的软骨，将治疗性超声能量引导到损伤的软骨，烧蚀损伤的软骨的至少一部分并改善损坏的软骨。该方法可以包括聚焦治疗超声能量以在损伤的软骨的一部分中产生至少一个病变。该方法还可以包括成像损伤的软骨。该方法可以包括增加对感兴趣区域的血液灌注。该方法可以包括用受治疗的超声能量将损伤的软骨焊接在一起。该方法可以包括切割受损的软骨，并用治疗超声能量从关节中去除它。该方法可以包括用治疗性超声能量平滑软骨。该方法可以包括再生软骨。

5. 发明申请

WO2008137944A1 METHODS AND SYSTEMS FOR COUPLING AND FOCUSING ACOUSTIC ENERGY USING A COUPLER MEMBER 审中-公开
标题翻译：使用联轴器会员耦合和聚焦声学能量的方法和系统
公开(公告)号：WO2008137944A1
公开(公告)日：2008-11-13
申请号：PCT/US2008/062932
申请日：2008-05-07
申请人： GUIDED THERAPY SYSTEMS, LLC. , SLAYTON, Michael H. , BARTHE, Peter G. , JAEGER, Paul, M.
发明人： SLAYTON, Michael H. , BARTHE, Peter G. , JAEGER, Paul, M.
IPC分类号： A61B8/00 , G10K11/30 , G10K11/02 , G01N29/28 , A61K49/22
CPC分类号： A61B8/4281 , A61K49/226 , G10K11/02 , G10K11/30
摘要： An exemplary system for coupling acoustic energy using an encapsulated coupler member comprises a display or indicator, a control system, a probe, and a coupler member. This invention provides a coupler member (1) adjustably configured to perform at least one of (i) providing a standoff, (ii) focusing or defocusing energy, and (iii) coupling energy. An exemplary gel coupler member is configured to hold the shape of a lens geometry. In one aspect of the present invention, gel coupler member comprises water, glycerol, and polyvinyl alcohol, and exhibits an increased desiccation time and shelf life when compared to the prior art. The probe can comprise various probe and/or transducer configurations. In an exemplary embodiment, the probe delivers focused, unfocused, and/or defocused ultrasound energy to the region of interest. Imaging and/or monitoring may alternatively be coupled and/or co-housed with an ultrasound system contemplated by the present invention.
摘要翻译：使用封装的耦合器部件耦合声能的示例性系统包括显示器或指示器，控制系统，探针和耦合器部件。本发明提供了一种可调节地配置成执行（i）提供支座，（ii）聚焦或散焦能量和（iii）耦合能量中的至少一个的耦合器部件（1）。示例性的凝胶耦合器构件被配置为保持透镜几何形状。在本发明的一个方面，凝胶偶联剂包含水，甘油和聚乙烯醇，并且与现有技术相比表现出增加的干燥时间和保存期限。探头可以包括各种探头和/或换能器构造。在示例性实施例中，探针将聚焦的，未聚焦的和/或散焦的超声能量传递到感兴趣的区域。可以与本发明预期的超声系统可以联接和/或共同成像和/或监视。

6. 发明申请

WO2022197697A1 METHOD FOR MID-INTENSITY, NON-ABLATIVE ACOUSTIC TREATMENT OF FOOD PRODUCTS 审中-公开
公开(公告)号：WO2022197697A1
公开(公告)日：2022-09-22
申请号：PCT/US2022/020376
申请日：2022-03-15
申请人： GUIDED THERAPY SYSTEMS, LLC
发明人： SLAYTON, Michael H.
IPC分类号： A61H23/00 , A61B17/50 , A61B17/225 , A61B18/00
摘要： A method for mid-intensity non-ablative acoustic treatment of a target volume is disclosed. The method involves continuously moving an ultrasound probe across an external surface while emitting non-ablative ultrasound into the target volume in a non-ablative ultrasound beam profile. The method terminates energy delivery if movement speed is below a speed threshold. The non-ablative ultrasound beam profile provides substantially uniform heating throughout a treatment volume. The heating is non-ablative and triggers a healing response in the target volume.

7. 发明申请

WO2022197663A1 SYSTEM FOR MID-INTENSITY, NON-ABLATIVE ACOUSTIC TREATMENT OF INJURED TISSUE 审中-公开
公开(公告)号：WO2022197663A1
公开(公告)日：2022-09-22
申请号：PCT/US2022/020321
申请日：2022-03-15
申请人： GUIDED THERAPY SYSTEMS, LLC
发明人： SLAYTON, Michael, H.
IPC分类号： A61N7/00
摘要： A system for mid-intensity, non-ablative acoustic treatment of injured tissue is disclosed. The system produces a non-ablative therapeutic ultrasound beam profile within the injured tissue. The system terminates energy delivery if a motion sensor senses movement speed below a speed threshold. The non-ablative therapeutic ultrasound beam profile provides substantially uniform heating throughout a treatment volume. The heating is non- ablative and triggers a healing response in the injured tissue.

8. 发明申请

WO2016164829A1 SYSTEM AND METHOD FOR INCREASED CONTROL OF ULTRASOUND TREATMENT 审中-公开
标题翻译：超声治疗的增加控制系统与方法
公开(公告)号：WO2016164829A1
公开(公告)日：2016-10-13
申请号：PCT/US2016/026794
申请日：2016-04-08
申请人： GUIDED THERAPY SYSTEMS, LLC
发明人： SLAYTON, Michael H. , BARTHE, Peter G.
IPC分类号： A61N7/02 , A61N7/00 , A61B18/00 , A61B90/00 , A61B34/20 , A61B17/00
CPC分类号： A61N7/00 , A61B2017/00039 , A61B2018/00904 , A61B2034/2048 , A61B2034/2055 , A61B2034/2059 , A61B2090/065 , A61B2560/0406 , A61B2560/0418 , A61N7/02
摘要： This disclosure provides systems and methods for delivery of therapeutic ultrasound energy that enables a user to delivery the ultrasound energy in an arbitrary treatment pattern by moving an ultrasound probe in an arbitrary surface pattern. The systems and methods allow ultrasound treatment in anatomically tight areas that cannot be treated with existing ultrasound probes.
摘要翻译：本公开提供用于递送治疗性超声能量的系统和方法，其使得用户能够以任意表面图案移动超声波探头以任意处理模式递送超声能量。系统和方法允许在解剖学上紧密的区域进行超声处理，这些区域不能用现有的超声波探头进行治疗。

9. 发明申请

WO2013009784A2 SYSTEMS AND METHOD FOR ACCELERATING HEALING OF IMPLANTED MATERIAL AND/OR NATIVE TISSUE 审中-公开
标题翻译：用于加速植入材料和/或原始组织的加工的系统和方法
公开(公告)号：WO2013009784A2
公开(公告)日：2013-01-17
申请号：PCT/US2012/046122
申请日：2012-07-10
申请人： GUIDED THERAPY SYSTEMS, LLC , SLAYTON, Michael, H.
发明人： SLAYTON, Michael, H.
IPC分类号： A61N7/00 , A61B18/00 , A61B18/18 , A61N5/10 , A61N1/44
CPC分类号： A61N7/00 , A61B18/18 , A61B2018/00642 , A61M37/0092 , A61N7/02 , A61N2007/0004 , A61N2007/0017 , A61N2007/0034 , A61N2007/0039 , A61N2007/0052 , A61N2007/006 , A61N2007/0073 , A61N2007/0078 , A61N2007/027
摘要： Various embodiments provide methods and systems for ultrasound treatment of tissue are provided. Accordingly, a method can include locating an implant in a site in a body, directing a medicant to at least one of the implant and the site, directing ultrasound energy to the site, and accelerating healing of the implant and/or native tissue at the site.
摘要翻译：提供了各种实施例提供了用于组织超声处理的方法和系统。因此，一种方法可以包括将植入物定位在体内的部位中，将药物定向到至少一个植入物和位点，将超声能量引导到部位，以及加速植入物和/或天然组织的愈合现场。

10. 发明申请

WO2008137948A1 METHOD AND SYSTEM FOR COMBINED ENERGY THERAPY PROFILE 审中-公开
标题翻译：用于组合能量治疗概况的方法和系统
公开(公告)号：WO2008137948A1
公开(公告)日：2008-11-13
申请号：PCT/US2008/062936
申请日：2008-05-07
申请人： GUIDED THERAPY SYSTEMS, LLC. , SLAYTON, Michael H , BARTHE, Peter G , MAKIN, Inder Raj S.
发明人： SLAYTON, Michael H , BARTHE, Peter G , MAKIN, Inder Raj S.
IPC分类号： A61N7/00 , A61N7/02
CPC分类号： A61N7/02 , A61B8/4281 , A61N2007/0008 , A61N2007/0052 , A61N2007/0078
摘要： A method and system for treating tissue with a combined therapy profile is disclosed. In one exemplary embodiment, ultrasound energy is used to treat numerous depths of tissue within a region of interest and the spatial and temporal properties of the ultrasound energy are varied for more effective treatment. The method and system of the present invention are configured to treat all of the tissue from the surface on down and not spare intervening tissue.
摘要翻译：公开了一种用组合治疗方案处理组织的方法和系统。在一个示例性实施例中，使用超声能量来治疗感兴趣区域内的组织的许多深度，并且改变超声能量的空间和时间属性以进行更有效的治疗。本发明的方法和系统被配置为从表面上向下处理所有的组织，而不是备用的中间组织。

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