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1. 发明申请

WO2006036939A2 SELF-CONSTRAINED SEGMENTED STENTS AND METHODS FOR THEIR DEPLOYMENT 审中-公开
标题翻译：自我约束的分支手段及其部署方法
公开(公告)号：WO2006036939A2
公开(公告)日：2006-04-06
申请号：PCT/US2005/034534
申请日：2005-09-26
申请人： XTENT, INC. , ACOSTA, Pablo , WELK, Craig , GRAINGER, Jeffry, J.
发明人： ACOSTA, Pablo , WELK, Craig , GRAINGER, Jeffry, J.
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/91 , A61F2/915 , A61F2002/826 , A61F2002/828 , A61F2002/91508 , A61F2002/91533 , A61F2002/9155 , A61F2002/91591 , A61F2002/9505 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2250/0071
摘要： A self-expanding stent includes a plurality of segments having a collapsed configuration and an expanded configuration. Preferably, the segments are unconnected to each other in at least the expanded configuration. The segments include restraining structures that temporarily restrain them from expansion until activated. This allows the user to position the desired number of segments at a treatment site and to deploy them simultaneously, thereby avoiding misalignment, overlap, and excessive spacing between segments. In preferred embodiments, multiple segmented stents of user-selectable length may be deployed at multiple locations in a single intervention.
摘要翻译：自扩张支架包括具有折叠构型和扩张构型的多个段。优选地，片段至少在扩展配置中彼此不连接。这些片段包括限制结构，其暂时限制它们在被激活之前不被扩展。这允许用户将期望数量的片段定位在治疗部位并同时展开，从而避免片段之间的不对准，重叠和间隔过大。在优选实施例中，可以在单个干预中的多个位置部署用户可选长度的多个分段支架。

2. 发明申请

WO2010132309A1 KNOTLESS SUTURE ANCHOR AND METHODS OF USE 审中-公开
标题翻译：无钥匙锚杆及其使用方法
公开(公告)号：WO2010132309A1
公开(公告)日：2010-11-18
申请号：PCT/US2010/034115
申请日：2010-05-07
申请人： FOUNDRY NEWCO XI, INC. , HENDRICKSEN, Michael, J. , HIROTSUKA, Mark , DEEM, Mark, E. , GRAINGER, Jeffry, J. , GITTINGS, Darin
发明人： HENDRICKSEN, Michael, J. , HIROTSUKA, Mark , DEEM, Mark, E. , GRAINGER, Jeffry, J. , GITTINGS, Darin
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B17/0482 , A61B17/06166 , A61B90/92 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0416 , A61B2017/0432 , A61B2017/0433 , A61B2017/0438 , A61B2017/044 , A61B2017/0441 , A61B2017/0445 , A61B2017/0448 , A61B2017/045 , A61B2017/0451 , A61B2017/0453 , A61B2017/0454 , A61B2017/0461 , A61B2017/0496 , A61B2017/06142 , A61B2090/0807 , B29C45/00
摘要： Various devices, systems and methods for knotless suturing of tissue are disclosed. These devices allow sutures to be anchored to bone, and more specifically provide a suture anchor which eliminates the need for knotting the suture. Thus, damaged tissue may be re-attached to a substrate tissue. The anchors have a minimum of moving parts may be suited to being a single molded polymer construction. The anchors will find particular utility in hip and shoulder arthroscopy, e.g. labral re-attachment and similar procedures.
摘要翻译：公开了用于组织的无缝缝合的各种装置，系统和方法。这些装置允许缝合线锚固到骨骼上，并且更具体地提供缝合锚固件，其消除了缝合缝合的需要。因此，损伤的组织可以重新连接到基底组织。锚固件具有最小的移动部件可以适合于单一的模制聚合物构造。锚固器将在髋关节和肩关节镜下发现特别的实用性，例如乳头再次附着和类似手术。

3. 发明申请

WO2006036939A3 SELF-CONSTRAINED SEGMENTED STENTS AND METHODS FOR THEIR DEPLOYMENT 审中-公开
标题翻译：自我约束的分支手段及其部署方法
公开(公告)号：WO2006036939A3
公开(公告)日：2007-05-24
申请号：PCT/US2005034534
申请日：2005-09-26
申请人： XTENT INC , ACOSTA PABLO , WELK CRAIG , GRAINGER JEFFRY J
发明人： ACOSTA PABLO , WELK CRAIG , GRAINGER JEFFRY J
IPC分类号： A61F2/82
CPC分类号： A61F2/95 , A61F2/91 , A61F2/915 , A61F2002/826 , A61F2002/828 , A61F2002/91508 , A61F2002/91533 , A61F2002/9155 , A61F2002/91591 , A61F2002/9505 , A61F2220/0008 , A61F2220/0016 , A61F2220/0025 , A61F2250/0071
摘要： A self-expanding stent includes a plurality of segments having a collapsed configuration and an expanded configuration. Preferably, the segments are unconnected to each other in at least the expanded configuration. The segments include restraining structures that temporarily restrain them from expansion until activated. This allows the user to position the desired number of segments at a treatment site and to deploy them simultaneously, thereby avoiding misalignment, overlap, and excessive spacing between segments. In preferred embodiments, multiple segmented stents of user-selectable length may be deployed at multiple locations in a single intervention.
摘要翻译：自扩张支架包括具有折叠构型和扩张构型的多个段。优选地，片段至少在扩展配置中彼此不连接。这些片段包括限制结构，其暂时限制它们在被激活之前不被扩展。这允许用户将期望数量的片段定位在治疗部位并同时展开，从而避免片段之间的不对准，重叠和间隔过大。在优选实施例中，可以在单个干预中的多个位置部署用户可选长度的多个分段支架。

4. 发明申请

WO2005037058A2 FIXED STENT DELIVERY DEVICES AND METHODS 审中-公开
标题翻译：固定支架装置和方法
公开(公告)号：WO2005037058A2
公开(公告)日：2005-04-28
申请号：PCT/US2004/031839
申请日：2004-09-28
申请人： XTENT, INC. , ANDREAS, Bernard , GRAINGER, Jeffry, J.
发明人： ANDREAS, Bernard , GRAINGER, Jeffry, J.
IPC分类号： A61B
CPC分类号： A61F2/958 , A61F2002/826 , A61F2002/9583
摘要： Stent delivery devices and methods include multiple stents or stent segments mounted at fixed positions on an expandable member of the stent delivery catheter. One or more of the fixed-position stents may be selectively deployed in a body lumen such as a blood vessel by positioning one or more sheaths to constrain some stents while exposing others for deployment. Some embodiments include two axially movable sheaths for serially deploying stents while containing a portion of the expandable balloon from which stents have been deployed. Other embodiments include inner and outer balloon shafts to allow the balloon to be retracted into the delivery catheter as stents are deployed. Devices and methods of the invention provide enhanced serial deployment of multiple stents or stent segments while reducing the risk of damage to an expandable deployment member.
摘要翻译：支架递送装置和方法包括安装在支架输送导管的可扩张构件上的固定位置处的多个支架或支架段。固定位置支架中的一个或多个可以通过定位一个或多个护套来限制一些支架，同时暴露其他支架以进行部署，可选择性地部署在诸如血管的体腔内。一些实施例包括用于串联展开支架的两个可轴向移动的护套，同时包含展开支架已部署的可膨胀气囊的一部分。其他实施例包括内和外球囊轴，以允许气囊在支架展开时缩回到输送导管中。本发明的装置和方法提供了多个支架或支架段的增强的连续部署，同时降低了对可扩展展开构件的损害风险。

5. 发明申请

WO2005037130A3 STENT DELIVERY DEVICES AND METHODS 审中-公开
标题翻译： STENT交付设备和方法
公开(公告)号：WO2005037130A3
公开(公告)日：2006-03-02
申请号：PCT/US2004031853
申请日：2004-09-28
申请人： XTENT INC , ANDREAS BERNARD , GRAINGER JEFFRY J
发明人： ANDREAS BERNARD , GRAINGER JEFFRY J
IPC分类号： A61F2/06 , A61F2/84 , A61M29/00 , A61F2/04 , A61M11/00
CPC分类号： A61F2/958 , A61F2002/9583
摘要： Stent delivery devices and methods include a shuttle for carrying multiple stent segments, to avoid direct contact between the stent segments and an expandable member. A sheath is disposed over the expandable member such that when it is withdrawn, a distal portion of the expandable member is exposed to expand against the shuttle, thus expanding the shuttle and expanding and deploying a selected number of stent segments. To deploy a second selected number of stent segments, the sheath may be withdrawn further to expose more of the expandable member. Thus, one or more custom length stents may be deployed with a reduced risk of damage to the expandable member and the stent segments and enhanced ease and accuracy of stent placement at a treatment location.
摘要翻译：支架递送装置和方法包括用于承载多个支架段的梭子，以避免支架段和可扩张构件之间的直接接触。护套设置在可膨胀构件上方，使得当其被拉出时，可膨胀构件的远侧部分暴露以抵靠梭子膨胀，从而使梭子膨胀并展开并展开选定数量的支架段。为了部署第二选定数量的支架段，护套可以被进一步抽出以暴露更多的可扩张构件。因此，可以部署一个或多个定制长度支架，降低对可扩张构件和支架段损伤的风险，并且增加支架在治疗位置处的放置的容易性和准确性。

6. 发明申请

WO2005039449A1 IMPLANTABLE STENT DELIVERY DEVICES AND METHODS 审中-公开
标题翻译：可植入装置和方法
公开(公告)号：WO2005039449A1
公开(公告)日：2005-05-06
申请号：PCT/US2004/032015
申请日：2004-09-28
申请人： XTENT, INC. , ANDREAS, Bernard , GRAINGER, Jeffry, J.
发明人： ANDREAS, Bernard , GRAINGER, Jeffry, J.
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/958 , A61F2002/826 , A61F2250/0071 , A61M2025/0681
摘要： Stent delivery devices include at least one implantable carrier (21) and/or membrane for carrying stents or stent segments (32) over an expandable member (24). At least a portion of the implantable carrier is expandable by the expandable member to deploy the portion of the carrier and one or more stent segments disposed thereon. A sheath (25) may be retracted to expose and expand a distal portion of the expandable member to expand and deploy a distal portion of the carrier and the stent segment(s) disposed thereon. Stent delivery devices and methods provide enhanced delivery of multiple stents or stent segments by delivering the segments while coupled with one or more implantable carriers and/or membranes that art typically flexible and dividable.
摘要翻译：支架递送装置包括至少一个可植入载体（21）和/或膜，用于在可扩张构件（24）上承载支架或支架段（32）。可植入载体的至少一部分由可膨胀构件扩张，以展开载体的一部分和设置在其上的一个或多个支架段。护套（25）可以缩回以露出并膨胀可扩张构件的远侧部分，以扩展和展开载体和设置在其上的支架段的远端部分。支架递送装置和方法通过递送片段同时与一种或多种可植入的载体和/或膜（通常是灵活和可分割的）耦合而提供多个支架或支架段的增强递送。

7. 发明申请

WO2005037130A2 STENT DELIVERY DEVICES AND METHODS 审中-公开
标题翻译： STENT交付设备和方法
公开(公告)号：WO2005037130A2
公开(公告)日：2005-04-28
申请号：PCT/US2004/031853
申请日：2004-09-28
申请人： XTENT, INC. , ANDREAS, Bernard , GRAINGER, Jeffry, J.
发明人： ANDREAS, Bernard , GRAINGER, Jeffry, J.
IPC分类号： A61F
CPC分类号： A61F2/958 , A61F2002/9583
摘要： Stent delivery devices and methods include a shuttle for carrying multiple stent segments, to avoid direct contact between the stent segments and an expandable member. A sheath is disposed over the expandable member such that when it is withdrawn, a distal portion of the expandable member is exposed to expand against the shuttle, thus expanding the shuttle and expanding and deploying a selected number of stent segments. To deploy a second selected number of stent segments, the sheath may be withdrawn further to expose more of the expandable member. Thus, one or more custom length stents may be deployed with a reduced risk of damage to the expandable member and the stent segments and enhanced ease and accuracy of stent placement at a treatment location.
摘要翻译：支架递送装置和方法包括用于承载多个支架段的梭子，以避免支架段和可扩张构件之间的直接接触。护套设置在可膨胀构件上方，使得当其被拉出时，可膨胀构件的远侧部分暴露以抵靠梭子膨胀，从而使梭子膨胀并展开并展开选定数量的支架段。为了部署第二选定数量的支架段，护套可以被进一步抽出以暴露更多的可扩张构件。因此，可以部署一个或多个定制长度支架，降低对可扩张构件和支架段损伤的风险，并且增加支架在治疗位置处的放置的容易性和准确性。

8. 发明申请

WO2012087842A1 SYSTEM FOR MITRAL VALVE REPAIR AND REPLACEMENT 审中-公开
标题翻译：麻醉阀维修和更换系统
公开(公告)号：WO2012087842A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/065627
申请日：2011-12-16
申请人： THE FOUNDRY, LLC , GIFFORD, III, Hanson S. , FANN, James I. , MORRISS, John , DEEM, Mark , GRAINGER, Jeffry J.
发明人： GIFFORD, III, Hanson S. , FANN, James I. , MORRISS, John , DEEM, Mark , GRAINGER, Jeffry J.
IPC分类号： A61F2/24
CPC分类号： A61F2/2454 , A61F2/2418 , A61F2/243 , A61F2/2445 , A61F2/2466 , A61F2220/0016 , A61F2220/0075 , A61F2230/0008 , A61F2250/0003 , A61F2250/0004 , A61F2250/0008 , A61F2250/006
摘要： Systems for mitral valve repair are disclosed where one or more mitral valve interventional devices may be advanced intravascularly into the heart of a patient and deployed upon or along the mitral valve to stabilize the valve leaflets. The interventional device may also facilitate the placement or anchoring of a prosthetic mitral valve implant. The interventional device may generally comprise a distal set of arms pivotably and/or rotating coupled to a proximal set of arms which are also pivotably and/or rotating coupled. The distal set of arms may be advanced past the catheter opening to a subannular position (e.g., below the mitral valve) and reconfigured from a low-profile delivery configuration to a deployed securement configuration. The proximal arm members may then be deployed such that the distal and proximal arm members may grip the leaflets between the two sets of arms to stabilize the leaflets.
摘要翻译：公开了用于二尖瓣修复的系统，其中一个或多个二尖瓣介入装置可以血管内推进到患者的心脏中并部署在二尖瓣上或沿着二尖瓣以稳定瓣膜小叶。介入装置还可以促进假体二尖瓣植入物的放置或锚定。介入装置通常可包括可枢转地和/或旋转地联接到也可枢转地和/或旋转耦合的近侧臂组的远侧臂组。远侧组的臂可以通过导管开口前进到子宫位置（例如，在二尖瓣下方），并且从低轮廓递送配置重新配置到展开的固定构造。近端臂构件然后可以被展开，使得远端和近端臂构件可以夹紧两组臂之间的传单以稳定传单。

9. 发明申请

WO2005037058A3 FIXED STENT DELIVERY DEVICES AND METHODS 审中-公开
标题翻译：固定支架装置和方法
公开(公告)号：WO2005037058A3
公开(公告)日：2006-08-17
申请号：PCT/US2004031839
申请日：2004-09-28
申请人： XTENT INC , ANDREAS BERNARD , GRAINGER JEFFRY J
发明人： ANDREAS BERNARD , GRAINGER JEFFRY J
IPC分类号： A61F2/82
CPC分类号： A61F2/958 , A61F2002/826 , A61F2002/9583
摘要： Stent delivery devices and methods include multiple stents or stent segments mounted at fixed positions on an expandable member of the stent delivery catheter. One or more of the fixed-position stents may be selectively deployed in a body lumen such as a blood vessel by positioning one or more sheaths to constrain some stents while exposing others for deployment. Some embodiments include two axially movable sheaths for serially deploying stents while containing a portion of the expandable balloon from which stents have been deployed. Other embodiments include inner and outer balloon shafts to allow the balloon to be retracted into the delivery catheter as stents are deployed. Devices and methods of the invention provide enhanced serial deployment of multiple stents or stent segments while reducing the risk of damage to an expandable deployment member.
摘要翻译：支架递送装置和方法包括安装在支架输送导管的可扩张构件上的固定位置处的多个支架或支架段。固定位置支架中的一个或多个可以通过定位一个或多个护套来限制一些支架，同时暴露其他支架以进行部署，可选择性地部署在诸如血管的体腔内。一些实施例包括用于串联展开支架的两个可轴向移动的护套，同时包含展开支架已部署的可膨胀气囊的一部分。其他实施例包括内和外球囊轴，以允许气囊在支架展开时缩回到输送导管中。本发明的装置和方法提供了多个支架或支架段的增强的连续部署，同时降低了对可扩展展开构件的损害风险。

10. 发明申请

WO2006065262A2 RAPID EXCHANGE INTERVENTIONAL DEVICES AND METHODS 审中-公开
标题翻译：快速交换传统设备和方法
公开(公告)号：WO2006065262A2
公开(公告)日：2006-06-22
申请号：PCT/US2005/010961
申请日：2005-03-30
申请人： XTENT, INC. , ANDREAS, Bernard , GRAINGER, Jeffry, J.
发明人： ANDREAS, Bernard , GRAINGER, Jeffry, J.
IPC分类号： A61M29/00
CPC分类号： A61M25/0169 , A61F2/958 , A61M25/10 , A61M2025/0183
摘要： Wire-guided interventional devices and methods are provided which enable faster and easier catheter exchanges. The interventional devices include a catheter shaft and a guidewire tube wherein the catheter shaft and the guidewire tube each have a length sufficient to extend to the vascular penetration when the interventional device is positioned at the treatment site. In some embodiments, a collar is disposed around the catheter shaft and guidewire tube that automatically inserts or removes the guidewire from the guidewire tube or automatically collapses or extends the guidewire tube as the catheter is introduced or withdrawn.
摘要翻译：提供导线介入装置和方法，其能够更快和更容易地进行导管交换。介入装置包括导管轴和导丝管，其中当介入装置位于治疗部位时，导管轴和导丝管各自具有足以延伸到血管穿透的长度。在一些实施例中，套环设置在导管轴和导丝管周围，自动地将导丝从导丝管插入或移除，或者当导管被引入或取出时自动地塌缩或延伸导丝管。

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