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    • 1. 发明申请
    • SENSOR ARRAY FOR SPR-BASED DETECTION.
    • 传感器阵列进行基于SPR的检测。
    • WO2009022246A1
    • 2009-02-19
    • PCT/IB2008/053029
    • 2008-07-29
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.MUSKENS, Otto L.GOMEZ RIVAS, JaimeVAN DIJK, Erik, M. H. P.KLUNDER, Derk J.W.
    • MUSKENS, Otto L.GOMEZ RIVAS, JaimeVAN DIJK, Erik, M. H. P.KLUNDER, Derk J.W.
    • G01N21/55
    • G01N21/554G01N2021/258
    • The invention relates to a sensor array for detecting the presence of a target, where a target is detected based on a detection of a surface plasmon resonance (SPR). The sensor array (30) comprises a carrier substrate (31), and a plurality of nano-sized particles (32) disposed on the carrier substrate. The surface plasmon resonance (SPR) for each of the nano-sized particles is correlated to a structural parameter of the nano-sized particles or group of nano-sized particles. The structural parameter and thereby the surface plasmon resonance is varied in a pre-defined way in at least a first area of the carrier substrate. The target is detected based on detecting intensity variations in the radiation resulting from the sensor array, the intensity variations being correlated to the pre-defined variation in the structural parameter. In embodiments, the sensor array may be a bio-sensor for the detection of bio-molecules.
    • 本发明涉及一种用于检测靶的存在的传感器阵列,其中基于表面等离子体共振(SPR)的检测来检测目标。 传感器阵列(30)包括载体衬底(31)和设置在载体衬底上的多个纳米尺寸颗粒(32)。 每个纳米尺寸颗粒的表面等离子体共振(SPR)与纳米尺寸颗粒或纳米尺寸颗粒组的结构参数相关。 结构参数以及由此的表面等离子体共振在载体衬底的至少第一区域中以预定义的方式变化。 基于检测由传感器阵列产生的辐射的强度变化来检测目标,强度变化与结构参数中的预定变化相关。 在实施例中,传感器阵列可以是用于检测生物分子的生物传感器。