专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2012137122A1 LIQUID REAGENT STORAGE AND OPERATION OF ANALYTICAL DEVICES 审中-公开
标题翻译：液体试剂储存和分析装置的操作
公开(公告)号：WO2012137122A1
公开(公告)日：2012-10-11
申请号：PCT/IB2012/051591
申请日：2012-04-02
申请人： BIOSURFIT, S.A. , ALBUQUERQUE, Carlota , TENREIRO, Tânia , REIS, Nuno , GARCIA DA FONSECA, João , MARQUES CALEIRO CABEÇA, Ricardo Manuel
发明人： ALBUQUERQUE, Carlota , TENREIRO, Tânia , REIS, Nuno , GARCIA DA FONSECA, João , MARQUES CALEIRO CABEÇA, Ricardo Manuel
IPC分类号： B65B11/52 , B01L3/02
CPC分类号： G01N1/28 , B01L3/502715 , B01L3/502738 , B01L3/523 , B01L2200/0642 , B01L2200/0689 , B01L2200/16 , B01L2300/0806 , B01L2300/087 , B01L2300/123 , B01L2400/0409 , B01L2400/0481 , B01L2400/0638 , B01L2400/0683 , B01L2400/086 , Y10T436/2575
摘要： Disclosed embodiments provide improved mechanisms for storing and introducing liquid volumes in a liquid handling device and, in particular, improved mechanisms for rupturing a liquid store to introduce liquid into the device, improvements to the stability of a liquid receiving chamber inside the device and improvements to liquid handling in the receiving chamber.
摘要翻译：公开的实施例提供用于在液体处理装置中存储和引入液体体积的改进机构，特别是用于破裂液体储存器以将液体引入装置的改进机构，改善装置内部的液体接收室的稳定性以及改进在接收室中的液体处理。

2. 发明申请

WO2011078713A1 SURFACE PLASMON RESONANCE DETECTION SYSTEM 审中-公开
标题翻译：表面质谱共振检测系统
公开(公告)号：WO2011078713A1
公开(公告)日：2011-06-30
申请号：PCT/PT2010/000055
申请日：2010-12-07
申请人： BIOSURFIT, S.A. , GARCIA DA FONSECA, João , DIAS PEDRO NICOLAU MANSO, João , MONTEIRO GOMES, Pedro Miguel , PINTO BORDEIRA, Sandro Miguel , SANTOS MANSO CÔRTE-REAL, José Pedro
发明人： GARCIA DA FONSECA, João , DIAS PEDRO NICOLAU MANSO, João , MONTEIRO GOMES, Pedro Miguel , PINTO BORDEIRA, Sandro Miguel , SANTOS MANSO CÔRTE-REAL, José Pedro
IPC分类号： G01N21/07 , G01N21/55 , B01L3/00 , G01N33/543 , G01N21/25 , G11B19/00 , G01N35/00 , G11B7/00
CPC分类号： G01N21/553 , B01L3/5027 , B01L2300/0803 , B01L2300/0816 , B01L2300/168 , G01N21/07 , G01N21/253 , G01N33/54373 , G01N35/00069
摘要： A system for detecting the presence of an analyte in a moving substrate or sample handling device is disclosed, providing means (26,30) for integrated triggering of data acquisition with a detector means (28) and data acquisition with a detector means (28). In particular, a surface Plasmon resonance "lab on disk" reader system is disclosed.
摘要翻译：公开了一种用于检测移动的衬底或样品处理装置中分析物的存在的系统，提供用于利用检测器装置（28）集成触发数据采集和用检测器装置（28）进行数据采集的装置（26,30）。特别地，公开了表面等离子共振“盘上实验室”读取器系统。

3. 发明申请

WO2011122972A2 LIQUID DISTRIBUTION AND METERING 审中-公开
标题翻译：液体分配和计量
公开(公告)号：WO2011122972A2
公开(公告)日：2011-10-06
申请号：PCT/PT2011/000009
申请日：2011-03-26
申请人： BIOSURFIT, S.A. , GARCIA DA FONSECA, João , ESTEVES REIS, Nuno Alexandre
发明人： GARCIA DA FONSECA, João , ESTEVES REIS, Nuno Alexandre
IPC分类号： B01L3/00
CPC分类号： F17D1/08 , B01L3/50273 , B01L2200/0605 , B01L2200/0621 , B01L2200/0642 , B01L2300/048 , B01L2300/0806 , B01L2300/0864 , B01L2300/087 , B01L2400/0406 , B01L2400/0409 , Y10T137/87249 , Y10T436/2575
摘要： Devices for handling liquid, for example microfluidic devices, are described, which are rotatable about an axis of rotation to drive liquid flow within the device. The 5 devices provide one or more of an aliquoting structure having a plurality of daisy chained aliquoting chambers for providing a plurality of aliquots, arrangements for sequencing the dispensing of the aliquots by controlling the rotation of the device and arrangements for ensuring that a fault condition can be detected when insufficient liquid is present in the device to fill 10 all aliquots. Further disclosed are arrangements for ensuring a detection chamber of the device remains filled with liquid, arrangements for reducing the risk of air ingress to the detection chamber on repeated emptying and filling of a supply structure and arrangements for reducing the risk of bubble formation when filling the detection chamber. A corresponding system for operating the 15 device and method for processing of a sample using the device is also disclosed.
摘要翻译：描述了用于处理液体的装置，例如微流体装置，其可围绕旋转轴线旋转以驱动装置内的液体流。 5个装置提供一个或多个等分结构，其具有多个菊花链等分装置，用于提供多个等分试样，用于通过控制装置的旋转来排序等分试样的排列和用于确保故障状态的装置在装置中存在不足的液体以填充10个所有等分试样时检测。进一步公开的是用于确保装置的检测室保持充满液体的布置，用于减少在反复排空和填充供应结构时空气进入检测室的风险的布置以及当填充填料时降低气泡形成的风险的布置检测室。还公开了一种用于操作该装置的方法和用于使用该装置处理样品的方法的相应系统。

4. 发明申请

WO2002082173A3 PROCESS FOR PREPARING ALIGNMENT LAYERS WITH PREDETERMINED AZIMUTHAL ANCHORING PROPERTIES TO BE USED IN LIQUID CRYSTAL DEVICES 审中-公开
公开(公告)号：WO2002082173A3
公开(公告)日：2002-10-17
申请号：PCT/PT2002/000006
申请日：2002-04-04
申请人： LIQUID CRYSTAL TECHNOLOGIES, TECNOLOGIA E EQUIPAMENTO MULTIMÉDIA, LDA. , UNIVERSITE LOUIS PASTEUR , DE OLIVEIRA GARCIA DA FONSECA, João Manuel , GALERNE, Yves
发明人： DE OLIVEIRA GARCIA DA FONSECA, João Manuel , GALERNE, Yves
IPC分类号： G02F1/1337
摘要： The present invention relates to a process for preparing alignment layers with predetermined azimuthal anchoring properties, to be used in liquid crystal devices. The invention relates to the modification of the substrate's topography by means of an abrasive jet in oblique incidence. Using this process, one can obtain alignment layers with a predetermined azimuthal anchoring orientation and a predetermined azimuthal anchoring strength.

5. 发明申请

WO2012131598A1 LIQUID SWITCHING, DOSING AND PUMPING 审中-公开
标题翻译：液体开关，排料和泵送
公开(公告)号：WO2012131598A1
公开(公告)日：2012-10-04
申请号：PCT/IB2012/051490
申请日：2012-03-28
申请人： BIOSURFIT, S.A. , TENREIRO, Tânia , REIS, Nuno , GARCIA DA FONSECA, João
发明人： TENREIRO, Tânia , REIS, Nuno , GARCIA DA FONSECA, João
IPC分类号： B01L3/00 , F16K99/00
CPC分类号： A61M1/3693 , B01L3/50273 , B01L2200/0621 , B01L2200/10 , B01L2300/087 , B01L2300/14 , B01L2400/0409 , B01L2400/0688 , B01L2400/0694 , B04B5/0407
摘要： A liquid handling device is provided with an upstream liquid handling structure connected to a downstream liquid handling structure by a conduit. The upstream and downstream liquid handling structures are sealed or sealable such that the conduit provides the only fluidic communication paths between the upstream and downstream liquid handling structure. The device is arranged such that a driving force causes liquid in the upstream liquid handling structure to at least partially fill the conduit to separate gas in the upstream liquid handling structure from gas in the downstream liquid handling structure. With the device set up such that the two gas volumes are separated by a liquid volume, gas pressures and liquid flow in the device can be controlled by control of the driving force. In one particular embodiment, the device is arranged for rotation about an axis of rotation to provide the driving force.
摘要翻译：液体处理装置设置有通过管道连接到下游液体处理结构的上游液体处理结构。上游和下游液体处理结构被密封或可密封，使得导管在上游和下游液体处理结构之间提供唯一的流体连通路径。该装置被布置成使得驱动力使得上游液体处理结构中的液体至少部分地填充导管，以使上游液体处理结构中的气体与下游液体处理结构中的气体分离。在装置设置使得两个气体体积被液体体积分开的情况下，可以通过控制驱动力来控制装置中的气体压力和液体流量。在一个特定实施例中，该装置布置成围绕旋转轴线旋转以提供驱动力。

6. 发明申请

WO2012131556A1 CONTROL OF LIQUID FLOW SEQUENCE ON MICROFLUIDIC DEVICE 审中-公开
标题翻译：微流控器件液相流动控制
公开(公告)号：WO2012131556A1
公开(公告)日：2012-10-04
申请号：PCT/IB2012/051411
申请日：2012-03-23
申请人： BIOSURFIT, S.A. , GARCIA DA FONSECA, João , REIS, Nuno , TENREIRO, Tânia , PINTO BORDEIRA, Sandro Miguel
发明人： GARCIA DA FONSECA, João , REIS, Nuno , TENREIRO, Tânia , PINTO BORDEIRA, Sandro Miguel
IPC分类号： B01L3/00
CPC分类号： B01L3/50273 , B01D21/26 , B01L3/502738 , B01L2200/0621 , B01L2200/10 , B01L2300/0636 , B01L2300/0803 , B01L2300/0806 , B01L2400/0409 , B01L2400/0688 , B01L2400/0694 , B04B13/00 , G05D7/0694 , Y10T137/0318 , Y10T137/8593
摘要： Described embodiments provide devices, systems and methods for sequencing liquid flow in response to a driving force by entrapping and releasing gas between volumes of liquid in a controlled manner. In one particular form, a centrifugal "lab on a disk" device is provided to drive liquid flow and sequencing by virtue of the centrifugal force and in one particular form a radially inward bend conduit is used in connection with controllably trapping and releasing gas between liquid volumes.
摘要翻译：描述的实施例提供了用于通过以受控的方式在体积的液体之间捕集和释放气体来响应于驱动力来对液体流进行排序的装置，系统和方法。在一种特定形式中，提供离心式“实验室盘”装置，借助于离心力来驱动液体流动和排序，并且在一种特定形式中，径向向内弯曲导管与液体之间可控地捕获和释放气体卷。

7. 发明申请

WO2010077159A1 ANALYTICAL ROTORS AND METHODS FOR ANALYSIS OF BIOLOGICAL FLUIDS 审中-公开
标题翻译：分析转子和生物流体分析方法
公开(公告)号：WO2010077159A1
公开(公告)日：2010-07-08
申请号：PCT/PT2009/000081
申请日：2009-12-30
申请人： BIOSURFIT, S.A. , GARCIA DA FONSECA, João , ESTEVES REIS, Nuno Alexandre , BURGER, Robert
发明人： GARCIA DA FONSECA, João , ESTEVES REIS, Nuno Alexandre , BURGER, Robert
IPC分类号： B01L3/00 , G01N21/07
CPC分类号： B01L3/50273 , B01L2300/0803 , B01L2300/0861 , B01L2400/0406 , B01L2400/0409 , B01L2400/0688
摘要： Devices for generating discrete flow of liquids in response to a driving force are disclosed, for example centrifugal microfluidic devices for generating discrete flow in response to a constant driving force. The devices find applications in liquid mixing, for example for diluting samples, such as blood plasma samples.
摘要翻译：公开了用于响应于驱动力产生离散流体的装置，例如用于响应于恒定驱动力产生离散流动的离心微流体装置。这些装置可用于液体混合，例如稀释样品，如血浆样品。

8. 发明申请

WO2008060172A1 DYNAMIC DETECTION DEVICE BASED ON SURFACE PLASMON RESONANCE EFFECT 审中-公开
标题翻译：基于表面等离子体共振效应的动态检测装置
公开(公告)号：WO2008060172A1
公开(公告)日：2008-05-22
申请号：PCT/PT2007/000048
申请日：2007-11-15
申请人： Biosurfit, S.A. , GARCIA DA FONSECA, João
发明人： GARCIA DA FONSECA, João
IPC分类号： G01N21/55
CPC分类号： G01N21/553
摘要： The present invention describes a detection device based on the surface plasmon resonance effect, comprising a radiation emitter (20) and a radiation detector (30), a fluidic substrate (40), a liquid crystal layer and respective control mechanism (80), wherein: (a) the fluidic substrate (40) includes channels (43) and at least one detection surface (42) containing a thin electrically conductive layer behaving like a diffraction grating; (b) the liquid crystal layer (80) is placed in between the radiation emitter (20) and the radiation detector (30) and is capable of presenting at least two types of orientation of its molecules in order to induce different levels of modification of the properties of the radiation outgoing (102) or radiation incident (101) onto the detection surface (42); (c) the control mechanism is present for controlling the average orientation of the molecules (83) of the liquid crystal layer (80), in order to adjust the modification of the radiation properties, to optimize detection of the surface plasmon resonance signal; (d) by exploiting the surface plasmon resonance effect, the arrangement enables to conduct measurements of chemical and/or biological events occurring in the vicinity of the detection surface (42) of the detection zone (41). Surface plasmon resonance detection is achieved through the adjustment of the properties of the radiation outgoing (102) or radiation incident (101) onto the detection surface (42) though the control of the liquid crystal layer (80).
摘要翻译：本发明描述了基于表面等离子体共振效应的检测装置，其包括辐射发射器（20）和辐射检测器（30），流体衬底（40），液晶层和相应的控制机构（80），其中：（a）流体衬底（40）包括通道（43）和至少一个检测表面（42），所述至少一个检测表面包含表现得像衍射光栅的薄导电层; （b）液晶层（80）放置在辐射发射器（20）和辐射探测器（30）之间，并且能够呈现其分子的至少两种类型的取向，以便引起不同程度的（102）或辐射入射（101）到检测表面（42）上的特性; （c）存在用于控制液晶层（80）的分子（83）的平均取向的控制机构，以便调整辐射特性的修改，优化表面等离子体共振信号的检测; （d）通过利用表面等离子体激元共振效应，该装置能够对在检测区（41）的检测表面（42）附近发生的化学和/或生物事件进行测量。表面等离子体共振检测是通过控制液晶层（80）来调节辐射出射（102）或入射辐射（101）到检测表面（42）上的特性来实现的。

9. 发明申请

WO2002059688A1 PROCESS FOR PREPARING AN ALIGNMENT LAYER WITH PREDETERMINED ANCHORING PROPERTIES AND LIQUID CRYSTAL DEVICE COMPRISING SUCH AN ALIGNMENT LAYER 审中-公开
标题翻译：用预定的锚固性质制备对准层的方法和包含这种对准层的液晶装置
公开(公告)号：WO2002059688A1
公开(公告)日：2002-08-01
申请号：PCT/PT2002/000002
申请日：2002-01-24
申请人： LIQUID CRYSTAL TECHNOLOGIES, TECNOLOGIA E EQUIPAMENTO MULTIMÉDIA, LDA. , UNIVERSITE LOUIS PASTEUR , DE OLIVEIRA GARCIA DA FONSECA, João, Manuel , GALERNE, Yves
发明人： DE OLIVEIRA GARCIA DA FONSECA, João, Manuel , GALERNE, Yves
IPC分类号： G02F1/1337
CPC分类号： G02F1/133788 , G02F1/133753
摘要： A process for preparing alignment layers to be used in liquid crystal display devices. It refers to the modification of the chemical functions at the surface of an organic layer to obtain a liquid crystal alignment layer, by means of UV irradiation of a liquid directly in contact with the organic layer or a reactive gas that contacts with the organic layer. With the use of this process, one may obtain alignment layers with a fixed and pre-determined anchoring angle (or pre-tilt) and a selected zenithal anchoring strength.
摘要翻译：一种制备用于液晶显示装置的取向层的方法。是指通过与有机层直接接触的液体的UV照射或与有机层接触的反应性气体，在有机层的表面改变化学功能以获得液晶取向层。通过使用该方法，可以获得具有固定和预定锚定角度（或预倾斜）和所选择的天顶锚定强度的对准层。

10. 发明申请

WO2010047609A1 JET DEFLECTION DEVICE 审中-公开
标题翻译：喷射偏转装置
公开(公告)号：WO2010047609A1
公开(公告)日：2010-04-29
申请号：PCT/PT2009/000055
申请日：2009-10-20
申请人： BIOSURFIT, S.A. , GARCIA DA FONSECA, João , ESTEVES, Nuno Alexandre Reis , BURGER, Robert
发明人： GARCIA DA FONSECA, João , ESTEVES, Nuno Alexandre Reis , BURGER, Robert
IPC分类号： G05D7/06 , B01L3/00
CPC分类号： G05D7/0694 , B01D17/0217 , B01D21/262 , B01L3/00 , G01N33/491 , Y10T137/0318 , Y10T137/8593 , Y10T436/111666 , Y10T436/2575
摘要： Devices for controlling fluid flow, in particular microfluidic devices, are described, which exploit gas/liquid interfaces to control liquid flow in accordance with application requirements. Devices for on/off flow switching, centrifugal separation, mixing, metering and aliquoting are described.
摘要翻译：描述了用于控制流体流动的装置，特别是微流体装置，其利用气体/液体界面来根据应用要求控制液体流动。描述了用于开/关流量切换，离心分离，混合，计量和等分装置的装置。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式