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1. 发明申请

WO2014136076A3 ASSEMBLY COMPRISING AN ABSORBER OF NEAR INFRARED (NIR) LIGHT COVALENTLY LINKED TO AN INHIBITOR OF CARBONIC ANHYDRASE 审中-公开
标题翻译：包含近红外（NIR）光的吸收体的组件，其与碳酸酐酶的抑制剂共价相连
公开(公告)号：WO2014136076A3
公开(公告)日：2014-11-20
申请号：PCT/IB2014059490
申请日：2014-03-06
申请人： CONSIGLIO NAZIONALE RICERCHE
发明人： PINI ROBERTO , RATTO FULVIO , TATINI FRANCESCA , FUSI FRANCO , CENTI SONIA , SCOZZAFAVA ANDREA , SUPURAN CLAUDIU TRANDAFIR , CARTA FABRIZIO , CAPACCIOLI SERGIO , WITORT EWA JANINA
IPC分类号： A61K49/22 , A61K41/00 , A61K47/48 , A61P35/00
CPC分类号： A61K31/185 , A61K41/0052 , A61K47/48884 , A61K47/6923 , A61K47/6929 , A61K49/22 , A61K49/221 , A61K49/225 , A61N5/062 , A61N5/0625
摘要： An assembly comprising an absorber of near infrared (NIR) light having an optical absorption cross section not lower than 100 nm2 covalently linked to an inhibitor of carbonic anhydrase (CA), process for its preparation and its use to hyperthermally target tumours or for treating other conditions in which the CA activity is involved is disclosed.
摘要翻译：一种组件，其包含与碳酸酐酶（CA）抑制剂共价连接的具有不低于100nm2的光吸收截面的近红外（NIR）光的吸收体，其制备方法及其用于超热靶向肿瘤或用于治疗其他披露了涉及CA活动的条件。

2. 发明申请

WO2014033690A3 THERMIONIC CONVERTER DEVICE 审中-公开
标题翻译： THERMIONIC转换器设备
公开(公告)号：WO2014033690A3
公开(公告)日：2014-07-03
申请号：PCT/IB2013058225
申请日：2013-09-02
申请人： CONSIGLIO NAZIONALE RICERCHE
发明人： TRUCCHI DANIELE MARIA , CAPPELLI EMILIA , ORLANDO STEFANO , SCITI DILETTA
IPC分类号： H01J45/00 , B23K26/00 , F24J2/48 , H01L35/00
CPC分类号： H02S40/44 , B23K26/0006 , B23K26/0084 , B23K26/0624 , B23K2201/35 , B23K2203/56 , F24J2/484 , H01J45/00 , H01L35/16 , H01L35/22 , H01L35/30 , H01L35/32 , H01L35/34 , H02S40/22 , Y02E10/40 , Y02E10/52
摘要： Converter device for converting energy from electromagnetic radiation, in particular concentrated solar energy, in electrical power, comprising a thermionic emitter (2) and an absorber (1) of electromagnetic radiation, configured to transform electromagnetic radiation energy to thermal energy, having an outer surface (10) configured to be exposed to electromagnetic radiation and an inner surface integrally coupled to the thermionic emitter (2), the outer surface (10) being provided with a sub-micrometer periodic surface structure, the thermionic emitter (2) being monolithically integrated on said inner surface of the absorber (1), the absorber (1) being made of a material selected from the group comprising or consisting of carbide or aluminium nitride-based ceramic materials, and pyrolitic graphite, the thermionic emitter (2) being made of a material selected from the group comprising or consisting of thin film diamond deposited through chemical vapour deposition (CVD), thin film titanium nitride (TiN) or molybdenum silicide or di carbides or di borides-based ceramic materials, and refractory metals.
摘要翻译：从电磁辐射转换能量，特别是集中的太阳能，在电力，包括：热电子发射体（2）和电磁辐射的吸收体（1），配置以变换电磁辐射能量为热能，其具有外表面转换器装置（10）配置成暴露于电磁辐射和整体地联接到热离子发射器（2），所述外表面（10）设置有一个亚微米周期性表面结构的内表面，所述热离子发射器（2）是单片集成在所述（1），吸收体（1）由从包括或由碳化物或铝构成的组中选择的材料的吸收体的内表面的氮化物为基础的陶瓷材料，和热解石墨，热离子发射器（2）由的材料，所述材料选自包括通过化学气相沉积（CVD），薄膜钛膜沉积的薄膜金刚石或由其组成的组氮化铟（TiN）或硅化钼或二碳化物或二硼化物基陶瓷材料，以及难熔金属。

3. 发明申请

WO2014002067A3 METHOD OF PROCESSING OPTICAL COHERENCE TOMOGRAPHY IMAGES 审中-公开
标题翻译：处理光学相干层析成像图像的方法
公开(公告)号：WO2014002067A3
公开(公告)日：2014-03-06
申请号：PCT/IB2013055320
申请日：2013-06-28
申请人： CONSIGLIO NAZIONALE RICERCHE , FOND TOSCANA GABRIELE MONASTERIO PER LA RICERCA MEDICA E DI SANITA PUBBLICA
发明人： CELI SIMONA , BERTI SERGIO
IPC分类号： G06T7/00 , A61B5/00 , G06T7/60
CPC分类号： G06T11/005 , A61B5/0066 , A61B5/0084 , A61B5/02007 , F04C2270/041 , G06T7/0002 , G06T7/0012 , G06T7/10 , G06T7/60 , G06T2207/10101 , G06T2207/20116 , G06T2207/30101
摘要： An automatic or semiautomatic method of processing intravascular Optical Coherence Tomography (OCT) images, comprising: pre-processing the primary image by segmenting the guidewire in the lumen to exclude it from the image, determining whether the lumen is open or closed; if the lumen is determined to be closed, performing a first automatic lumen segmentation procedure on the pre-processed image to define a perimeter line of the lumen, corresponding to the inner edge of the vessel wall, and determine a centroid CL of the lumen area; if the lumen is determined not to be closed, sequentially performing an automatic lumen closing procedure on the pre-processed image, and a second automatic lumen segmentation procedure, to define a perimeter line of the lumen, corresponding to the inner edge of the vessel wall, and determine a centroid CL of the lumen area; automatically finding an outer edge of the vessel wall and defining a first region of interest ROI1 between the inner edge and the outer edge of the lumen; automatically segmenting a fibrous plaque in the first region of interest ROI1 thereby defining a second region of interest ROI2 that contains the fibrous plaque, and segmenting a hyporeflective plaque, contained in a radial region that falls within ROI1 and is external to ROI2.
摘要翻译：一种用于处理血管内光学相干断层扫描（OCT）图像的自动或半自动方法，包括：通过将导丝分段在管腔中以将其从图像中排除来预处理主图像，确定管腔是打开还是关闭; 如果确定内腔闭合，则对预处理的图像执行第一自动内腔分割过程以限定对应于血管壁的内边缘的内腔的周界线，并且确定内腔区域的质心CL ; 如果确定内腔不闭合，则在预处理的图像上顺序地执行自动内腔闭合程序，以及第二自动内腔分割程序，以限定内腔的周界线，对应于血管壁的内边缘并确定管腔区域的质心CL; 自动找到血管壁的外边缘并且在内腔的内边缘和外边缘之间限定第一感兴趣区域ROI1; 自动分割第一感兴趣区域ROI1中的纤维斑块，从而限定包含纤维斑块的第二感兴趣区域ROI2，并且分割包含在落在ROI1内且在ROI2外部的径向区域中的低反射斑块。

4. 发明申请

WO2013118100A3 PROCESS FOR THE TREATMENT OF A POLYMER 审中-公开
标题翻译：聚合物处理方法
公开(公告)号：WO2013118100A3
公开(公告)日：2014-01-09
申请号：PCT/IB2013051068
申请日：2013-02-08
申请人： CONSIGLIO NAZIONALE RICERCHE
发明人： BENAGLIA MASSIMO
IPC分类号： C08F8/30 , C08G59/14 , C08G59/32
CPC分类号： C08G59/1483 , C08F8/30 , C08G59/1477 , C08G59/3209
摘要： Process for the treatment of a polymer or copolymer of poly (glycidyl methacrylate ) (PGMA); the process comprises reacting the polymer with a nucleophile selected from secondary amines, thiols and aromatic alcohols in the presence of an aprotic polar solvent having an oxygen capable of forming hydrogen bridges; the use of this solvent allows linear. homopolymers and linear block copolymers to be obtained under particularly efficient conditions. An additional treatment is also envisaged for introducing functionalities on the hydroxyl deriving from the opening of the epoxy ring. Finally, a controlled hyper-branching treatment is envisaged for obtaining nano-structured material.
摘要翻译：用于处理聚（甲基丙烯酸缩水甘油酯）（PGMA）的聚合物或共聚物的方法; 该方法包括在具有能够形成氢桥的氧的非质子极性溶剂的存在下使聚合物与选自仲胺，硫醇和芳族醇的亲核试剂反应; 该溶剂的使用允许线性。均聚物和线性嵌段共聚物。还设想了另外一种处理方法，用于在从环氧环的开口衍生的羟基上引入官能度。最后，设想用于获得纳米结构材料的受控超支化处理。

5. 发明申请

WO2013190587A2 METHOD FOR THE TREATMENT OF METAL SURFACES FOR BESTOWING THEREON A HIGH HYDROPHOBICITY AND OLEOPHOBICITY 审中-公开
标题翻译：用于处理金属表面的方法，以确保其具有高的疏水性和极性
公开(公告)号：WO2013190587A2
公开(公告)日：2013-12-27
申请号：PCT/IT2013000175
申请日：2013-06-21
申请人： CONSIGLIO NAZIONALE RICERCHE , ENEA ENTE NUOVE TEC
发明人： RAIMONDO MARIAROSA , BEZZI FEDERICA , BLOSI MAGDA , MINGAZZI CLAUDIO
IPC分类号： C23C18/12
CPC分类号： C23C18/1216 , C23C18/1295
摘要： A method for the treatment of metal surfaces comprising in succession: - a step of depositing a coating of metal oxide, in which on a metal surface a sol is deposited made from a colloidal suspension in water of one or more metal alkoxides M(OR)n in the presence of an acid catalyst, in which: M is comprised in the group consisting of Al, Ti, Si, Y, Zn, Zr; R is a linear or branched aliphatic chain C1-C4; - a step of consolidation, wherein the coating is subjected to a temperature between 150 °C and 900 °C; - a step of functionalization, in which the coating is treated with boiling water and/or steam for the realization of hydroxyl groups; - a second step of consolidation, wherein the coating is subjected to a temperature between 150 °C and 900 °C, and - a step of fluorination, wherein the coating is treated with a fluorinated compound.
摘要翻译：一种用于处理金属表面的方法，包括： - 沉积金属氧化物涂层的步骤，其中在金属表面上沉积由一种或多种金属醇盐M（OR）的水中的胶态悬浮液制成的溶胶，在酸催化剂存在下，其中：M包含在由Al，Ti，Si，Y，Zn，Zr组成的组中; R是直链或支链脂族链C1-C4; - 固结步骤，其中所述涂层经受在150℃和900℃之间的温度; - 功能化步骤，其中用沸水和/或蒸汽处理涂层以实现羟基; - 固结的第二步骤，其中所述涂层经受150℃至900℃的温度，和 - 氟化步骤，其中所述涂层用氟化合物处理。

6. 发明申请

WO2011117084A8 DIAGNOSTIC ASSAY FOR OBESITY AND RELATED DISORDERS 审中-公开
标题翻译：消化不良和相关疾病的诊断测定
公开(公告)号：WO2011117084A8
公开(公告)日：2012-05-10
申请号：PCT/EP2011053673
申请日：2011-03-11
申请人： CONSIGLIO NAZIONALE RICERCHE , MATARESE GIUSEPPE
发明人： MATARESE GIUSEPPE
IPC分类号： G01N33/564
CPC分类号： G01N33/564 , G01N2800/044
摘要： The disclosure relates to assays that detect the presence of auto-antibodies to antigens expressed by adipose tissue and the use of their detection in the diagnosis and/or treatment of obesity and/or metabolic syndrome.
摘要翻译：本公开涉及检测自身抗体对脂肪组织表达的抗原的存在以及其在诊断和/或治疗肥胖症和/或代谢综合征中的用途的测定。

7. 发明申请

WO2012042470A1 SAFETY DEVICE FOR THE SAFE USE OF INDUSTRIAL APPARATUSES AND ROBOTS, AND CONTROL METHOD FOR REALTIME VERIFICATION OF THE KINEMATIC STATE VALUES OF A ROBOTIZED APPARATUS 审中-公开
标题翻译：用于安全使用工业设备和机器人的安全装置，以及用于实时验证机动车辆的动力学状态值的控制方法
公开(公告)号：WO2012042470A1
公开(公告)日：2012-04-05
申请号：PCT/IB2011/054246
申请日：2011-09-27
申请人： C.N.R. CONSIGLIO NAZIONALE RICERCHE , VICENTINI, Federico , PEDROCCHI, Nicola , MALOSIO, Matteo
发明人： VICENTINI, Federico , PEDROCCHI, Nicola , MALOSIO, Matteo
IPC分类号： B25J9/16
CPC分类号： B25J9/1674 , B25J9/1694 , G05B2219/37497 , G05B2219/37546 , G05B2219/40549 , Y10S901/09
摘要： A safety device (1) for the safe use of industrial apparatuses and robots, comprising a movable structure (2), or robot, composed of rigid bodies (3) which are mutually articulated and provided with movement means (4) for moving them with respect to each other, the movement means (4) being managed by control and management means (5) for the movement of the movable structure (2) according to a series of nominal kinematic state values, moreover comprising inertial sensor means (6) which are applied to at least one of the rigid bodies (3) in order to make additional measurements of the kinematic state values of the movable structure (2) independently of the movement means (4) and are functionally associated with at least one safety module (7) which is connected to the control and management means (5) in order to verify the congruity between the kinematic state values measured by the inertial sensor means (6) and conditioned and integrated over time by means of a processing module (8) and an algorithm for integrating the inertial signal in order to estimate the spatial kinematic status of the rigid bodies (3) over time and the actual kinematic state values of the movable structure (2) measured by the control and management means (5), moreover comprising a processing module (8) for processing the signal originating from the inertial sensor means (6) which is functionally connected to the inertial sensor means (6) and is functionally connected to the safety module (7).
摘要翻译：一种用于安全使用工业设备和机器人的安全装置（1），包括由相互铰接的刚体（3）组成的可移动结构（2）或机器人，并且设有移动装置（4）移动装置（4）由用于根据一系列标称运动状态值移动可移动结构（2）的控制和管理装置（5）来管理，此外还包括惯性传感器装置（6），惯性传感器装置被施加到刚体（3）中的至少一个，以便独立于移动装置（4）对可移动结构（2）的运动状态值进行附加测量，并且在功能上与至少一个安全模块（ 7），其连接到控制和管理装置（5），以便验证由惯性传感器装置（6）测量的运动状态值与经过处理模块（8）的随时间调节和积分的运动状态值之间的一致性，以及用于积分惯性信号以估计刚体（3）随时间的空间运动状态和由控制和管理装置（5）测量的可移动结构（2）的实际运动状态值的算法，还包括处理模块（8），用于处理来自惯性传感器装置（6）的信号，功能上连接到惯性传感器装置（6）并且功能上连接到安全模块（7）。

8. 发明申请

WO2010116342A3 NON-STEROIDAL COMPOUNDS FOR ANDROGEN RECEPTOR MODULATION, PROCESSES FOR THE PREPARATION AND USES THEREOF 审中-公开
标题翻译：非甾体受体调节化合物，其制备方法及其用途
公开(公告)号：WO2010116342A3
公开(公告)日：2010-12-23
申请号：PCT/IB2010051548
申请日：2010-04-12
申请人： CONSIGLIO NAZIONALE RICERCHE , ISTITUTO SCIENT ROMAGNOLO PER LO STUDIO E LA CURA DEI TUMORI I R S T S R L , VARCHI GRETA , TESEI ANNA , GUERRINI ANDREA , BRIGLIADORI GIOVANNI
发明人： VARCHI GRETA , TESEI ANNA , BRIGLIADORI GIOVANNI
IPC分类号： A61K31/275 , C07C255/60 , C07C315/02 , C07C323/60 , C07D317/34
CPC分类号： C07C317/46 , C07C255/60 , C07C323/60 , C07D333/16
摘要： The present invention concerns compounds of general Formula (I) : method of preparation and uses thereof.
摘要翻译：本发明涉及通式（I）的化合物：其制备方法和用途。

9. 发明申请

WO2010057658A9 METHOD FOR PRODUCING A PACKAGING ANTIMICROBIAL FILM OF THERMOPLASTIC MATERIAL 审中-公开
标题翻译：生产热塑性材料包装抗微生物膜的方法
公开(公告)号：WO2010057658A9
公开(公告)日：2010-12-02
申请号：PCT/EP2009008290
申请日：2009-11-20
申请人： UNI DEGLI STUDI DI FOGGIA , CONSIGLIO NAZIONALE RICERCHE , DEL NOBILE MATTEO ALESSANDRO , CONTE AMALIA , BUONOCORE GIOVANNA GIULIANA , INCORONATO ANNA LUCIA , MASSARO ANGELANTONIO , PANZA OLIMPIA
发明人： DEL NOBILE MATTEO ALESSANDRO , CONTE AMALIA , BUONOCORE GIOVANNA GIULIANA , INCORONATO ANNA LUCIA , MASSARO ANGELANTONIO , PANZA OLIMPIA
IPC分类号： B65D81/28 , A01N25/34 , B29C47/00
CPC分类号： B29C43/003 , B29C47/0004 , B29C47/0021 , B29C47/10 , B29K2023/0633 , B29K2067/046 , B29K2105/0011 , B29K2995/006
摘要： A method is described for producing a film of thermoplastic material, more particularly of LDPE, PLA or PCL, incorporating substances with antimicrobial activity, comprising the steps of mixing at a temperature lower than or equal to 160°C a thermoplastic polymer having a melting point lower than or equal to 160°C and at least one substance with antimicrobial activity selected from the group consisting of lysozime, thymol and lemon extract; subjecting the mixture obtained to compression at the same temperature as that indicated above; cooling under compression to a temperature lower than or equal to 40°C, obtaining strips, which are divided into short pieces; feeding these short pieces into an extruder provided with a die and with heating means to bring the temperature thereinside to a value lower than or equal to 160°C; extruding the film through the die.
摘要翻译：描述了一种生产热塑性材料薄膜的方法，更具体地说是LDPE，PLA或PCL薄膜，其包含具有抗微生物活性的物质，该方法包括以下步骤：在低于或等于160℃的温度下混合具有熔点低于或等于160℃，并且至少一种具有抗微生物活性的物质选自由以下组成的组：枸杞，百里酚和柠檬提取物; 使所得混合物在与上述相同的温度下进行压缩; 在压缩下冷却至低于或等于40℃的温度，获得分成短片的条带; 将这些短片喂入装有模具的挤出机中，并用加热装置将其内部的温度降低到低于或等于160℃; 通过模头挤出薄膜。

10. 发明申请

WO2010057658A2 METHOD FOR PRODUCING A FILM OF THERMOPLASTIC MATERIAL CONTAINING A SUBSTANCE WITH ANTIMICROBIAL ACTIVITY AND USE OF THIS FILM IN THE PRODUCTION OF PACKAGING FOR FOOD 审中-公开
标题翻译：生产含有抗微生物活性的物质的热塑性材料薄膜的方法以及该膜在食品包装生产中的应用
公开(公告)号：WO2010057658A2
公开(公告)日：2010-05-27
申请号：PCT/EP2009008290
申请日：2009-11-20
申请人： UNI DEGLI STUDI DI FOGGIA , CONSIGLIO NAZIONALE RICERCHE , DEL NOBILE MATTEO ALESSANDRO , CONTE AMALIA , BUONOCORE GIOVANNA GIULIANA , INCORONATO ANNA LUCIA , MASSARO ANGELANTONIO , PANZA OLIMPIA
发明人： DEL NOBILE MATTEO ALESSANDRO , CONTE AMALIA , BUONOCORE GIOVANNA GIULIANA , INCORONATO ANNA LUCIA , MASSARO ANGELANTONIO , PANZA OLIMPIA
IPC分类号： B65D81/28 , A01N25/34 , B29C47/00
CPC分类号： B29C43/003 , B29C47/0004 , B29C47/0021 , B29C47/10 , B29K2023/0633 , B29K2067/046 , B29K2105/0011 , B29K2995/006
摘要： A method is described for producing a film of thermoplastic material, more particularly of LDPE, PLA or PCL, incorporating substances with antimicrobial activity, comprising the steps of mixing at a temperature lower than or equal to 160°C a thermoplastic polymer having a melting point lower than or equal to 160°C and at least one substance with antimicrobial activity selected from the group consisting of lysozime, thymol and lemon extract; subjecting the mixture obtained to compression at the same temperature as that indicated above; cooling under compression to a temperature lower than or equal to 40°C, obtaining strips, which are divided into short pieces; feeding these short pieces into an extruder provided with a die and with heating means to bring the temperature thereinside to a value lower than or equal to 160°C; extruding the film through the die.
摘要翻译：描述了一种用于生产热塑性材料薄膜，更具体地是LDPE，PLA或PCL的膜，其结合具有抗微生物活性的物质，包括以下步骤：在低于或等于160℃的温度下混合具有熔点低于或等于160℃的至少一种具有选自溶菌酶，百里香酚和柠檬提取物的抗微生物活性的物质; 将获得的混合物在与上述相同的温度下进行压缩; 在压缩下冷却至低于或等于40℃的温度，获得分为短片的条带; 将这些短片送入设置有模头的挤出机和加热装置，使其内部的温度达到低于或等于160℃的值; 将膜挤出通过模具。

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