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1. 发明申请

WO2010030485A1 DEVICE FOR OCCLUDING VASCULAR DEFECTS 审中-公开
标题翻译：用于监测血管缺损的装置
公开(公告)号：WO2010030485A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/054476
申请日：2009-08-20
申请人： AGA MEDICAL CORPORATION , AMPLATZ, Kurt , HEIDNER, Matthew, C. , REN, Brooke , RUSSO, Patrick , ADAMS, Daniel, O.
发明人： AMPLATZ, Kurt , HEIDNER, Matthew, C. , REN, Brooke , RUSSO, Patrick , ADAMS, Daniel, O.
IPC分类号： A61M29/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12159 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B90/39 , A61B2017/00575 , A61B2017/00601 , A61B2017/00606 , A61B2017/00831
摘要： A multi-layer occluder for treating a target site within the body is provided. The occluder may include first and second layers. For example, the first layer may include braided strands of metallic material, and the second layer may include braided strands of polymeric material. At least one of the first or second layers may be configured to facilitate thrombosis.
摘要翻译：提供了用于治疗身体内的靶部位的多层封堵器。封堵器可以包括第一和第二层。例如，第一层可以包括金属材料的编织线，并且第二层可以包括聚合材料的编织线。第一或第二层中的至少一个可以被配置为便于血栓形成。

2. 发明申请

WO2009002330A1 BRANCHED STENT/GRAFT AND METHOD OF FABRICATION 审中-公开
标题翻译：分支支架/格子和制造方法
公开(公告)号：WO2009002330A1
公开(公告)日：2008-12-31
申请号：PCT/US2007/021467
申请日：2007-10-05
申请人： AGA MEDICAL CORPORATION , ADAMS, Daniel, O.
发明人： ADAMS, Daniel, O.
IPC分类号： A61F2/06
CPC分类号： A61F2/90 , A61F2/06 , A61F2002/065 , A61F2220/0075 , A61F2230/001 , D04C1/06 , D04C3/48 , D10B2509/06
摘要： Branched braided stent or graft devices and processes for fabrication of the devices are disclosed in which a trunk portion and two hinge leg portions are fabricated in one piece braided from a single plurality of filaments, whereby the legs contain the full plurality of filaments and the trunk portion contains a subset of the same plurality of filaments. The fabrication process involves braiding the hinged legs on a mandrel while retaining loops of filament between the hinged leg portions for subsequent braiding of the trunk portion of the stent or graft.
摘要翻译：公开了分支编织支架或移植装置以及用于制造装置的方法，其中主体部分和两个铰链腿部由单个多根细丝编成一体制成，由此腿部包含完整的多根细丝，躯干部分包含相同多个细丝的子集。制造过程包括将铰链腿编织在心轴上，同时将细丝圈保持在铰链腿部之间，以便后续编织支架或移植物的躯干部分。

3. 发明申请

WO2005039419A1 PATENT FORAMEN OVALE CLOSURE SYSTEM 审中-公开
标题翻译：专利OVAM封闭系统
公开(公告)号：WO2005039419A1
公开(公告)日：2005-05-06
申请号：PCT/US2004/035303
申请日：2004-10-25
申请人： EV3, INC. , ADAMS, Daniel, O. , KUSLEIKA, Richard, S.
发明人： ADAMS, Daniel, O. , KUSLEIKA, Richard, S.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/0644 , A61B17/083 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/00615 , A61B2017/00623 , A61B2017/0649 , A61B2017/081
摘要： Devices and methods are disclosed herein for closing a patent foramen ovale. The devices are deployed at the foramen ovale to secure the septum secundum and septum primum together, thus sealing the foramen ovale. Disclosed are devices that may be inserted through a piercing in the septum secundum and septum primum to secure the septa together. Also disclosed is a delivery device to be used in connection with the devices and methods described. In some embodiments, the devices include an expandable member that secures at least one side of either the septum secundum or septum primum to secure the two septa together.
摘要翻译：本文公开了用于闭合卵孔的专利的装置和方法。将装置部署在卵圆孔处，以将隔膜和隔膜固定在一起，从而密封卵圆孔。公开了可以通过穿孔隔膜和隔膜插入以将隔垫固定在一起的装置。还公开了与所述装置和方法结合使用的输送装置。在一些实施例中，装置包括可扩张构件，其可固定隔膜隔膜或隔膜的至少一侧以将两个隔膜固定在一起。

4. 发明申请

WO2010011445A1 MULTI-LAYERED MEDICAL DEVICE FOR TREATING A TARGET SITE AND ASSOCIATED METHOD 审中-公开
标题翻译：用于处理目标位置的多层医疗设备及相关方法
公开(公告)号：WO2010011445A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/047629
申请日：2009-06-17
申请人： AGA Medical Corporation , HEIDNER, Matthew, C. , ADAMS, Daniel, O.
发明人： HEIDNER, Matthew, C. , ADAMS, Daniel, O.
IPC分类号： A61F2/06
CPC分类号： A61F2/06 , A61B17/12036 , A61B17/12109 , A61B17/12118 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00592 , A61B2017/00606 , A61B2017/00623 , A61B2017/00867 , A61F2/07 , A61F2/2493 , A61F2002/068
摘要： Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides a stent graft including an occlusive material having a preset, overlapping configuration comprising at least three inverted overlapping layers that are folded over one another. The at least three inverted overlapping layers are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.
摘要翻译：本发明的实施方案提供用于治疗体内靶点的医疗装置和方法，例如用于治疗血管异常。例如，一个实施例提供一种支架移植物，其包括具有预设的重叠构型的封闭材料，所述重叠配置包括彼此折叠的至少三个倒置的重叠层。所述至少三个倒置的重叠层被配置为以不重叠的构造分离并设置在导管内，并且当从导管展开时返回到预设的重叠构型。

6. 发明申请

WO2009014528A1 BRAIDED OCCLUSION DEVICE HAVING REPEATING EXPANDED VOLUME SEGMENTS SEPARATED BY ARTICULATION SEGMENTS 审中-公开
标题翻译：具有重新分配扩展部分的布线消除装置
公开(公告)号：WO2009014528A1
公开(公告)日：2009-01-29
申请号：PCT/US2007/022568
申请日：2007-10-25
申请人： AGA MEDICAL CORPORATION , ADAMS, Daniel, O.
发明人： ADAMS, Daniel, O.
IPC分类号： A61M29/00 , A61B17/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/12113 , A61B17/12122 , A61B17/12145 , A61B17/12154 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B2017/00526 , A61B2017/00867
摘要： The present invention provides a flexible, low profile vascular occlusion device having large volume filling capability and high metal content for fast occlusion, of the type fabricated from braided tubular metal fabric having an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a catheter to a treatment site and shaped to create an occlusion of an abnormal opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained. The device further includes a first shape formed from the braided tubular fabric consisting of a repeating pattern of expanded volume segments separated by small diameter articulation segments and a second overall device shape comprised of the first shape formed about itself in various shapes to occlude a vessel. In one embodiment a shaping wire contained coaxially within the tubular braid, provides or assists in the formation of the second overall device shape.
摘要翻译：本发明提供了一种具有大体积填充能力和高金属含量以用于快速闭塞的柔性低调血管闭塞装置，其由具有扩大的预设构型的编织管状金属织物制成，并且细长的折叠缩径直径构型用于通过导管到处理部位并成形以在身体器官或血管中产生异常开口的闭塞，所述编织金属织物具有记忆特性，从而当无约束时医疗装置趋向于返回到所述扩展的预设构型。该装置还包括由编织管状织物形成的第一形状，其由由小直径关节节段分隔开的膨胀体积段的重复图案组成，以及由形成为各种形状的第一形状的第二整体装置形状，以封闭血管。在一个实施例中，同轴地包含在管状编织物内的成形线提供或辅助形成第二整体装置形状。

7. 发明申请

WO2010096324A1 MEDICAL DEVICE WITH STIFFENER WIRE FOR OCCLUDING VASCULAR DEFECTS 审中-公开
标题翻译：具有刺激器线的医疗装置用于阻塞血管缺损
公开(公告)号：WO2010096324A1
公开(公告)日：2010-08-26
申请号：PCT/US2010/023862
申请日：2010-02-11
申请人： AGA MEDICAL CORPORATION , ADAMS, Daniel, O. , KARINIEMI, Ryan , REN, Brooke , HEIDNER, Matthew, C.
发明人： ADAMS, Daniel, O. , KARINIEMI, Ryan , REN, Brooke , HEIDNER, Matthew, C.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/12122 , A61B17/12172 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00615 , A61B2017/00623 , A61B2017/00867 , A61M25/00
摘要： Embodiments of the present invention provide devices and methods for treating various target sites. For example, one exemplary device includes a tubular structure having proximal and distal ends and at least one layer of braided material configured to facilitate thrombosis. The tubular structure includes an end section at the proximal or distal end having a cross-sectional dimension that is larger than that of an opening of the target site. The device also includes a stiffener wire coupled to the tubular structure, wherein the wire is configured to extend at least partially through the opening and facilitate securing the end section over the opening. The tubular structure and stiffener wire include respective preset, expanded configurations and are configured to be constrained to respective reduced configurations for delivery to the target site and to at least partially return to their respective preset, expanded configurations at the target site when unconstrained.
摘要翻译：本发明的实施方案提供了用于处理各种靶位点的装置和方法。例如，一个示例性装置包括管状结构，其具有近端和远端以及配置成便于血栓形成的至少一层编织材料。管状结构包括在近端或远端处的端部部分的横截面尺寸大于靶部位开口的截面尺寸。该装置还包括联接到管状结构的加强线，其中线被构造成至少部分地延伸穿过开口并有利于将端部部分固定在开口上。管状结构和加强筋包括相应的预设的扩展构型，并且被配置为被限制为相应的减小配置，用于递送到目标位置，并且在不受约束时至少部分地返回到其目标位置处的各自预设的扩展配置。

8. 发明申请

WO2010077599A1 BRAIDED OCCLUSION DEVICE HAVING REPEATING EXPANDED VOLUME SEGMENTS SEPARATED BY ARTICULATION SEGMENTS 审中-公开
标题翻译：具有重新分配扩展部分的布线消除装置
公开(公告)号：WO2010077599A1
公开(公告)日：2010-07-08
申请号：PCT/US2009/066964
申请日：2009-12-07
申请人： AGA MEDICAL CORPORATION , QIAN, Zhong , ADAMS, Daniel, O.
发明人： QIAN, Zhong , ADAMS, Daniel, O.
IPC分类号： A61F2/00
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12122 , A61B17/12145 , A61B17/1215 , A61B17/12163 , A61B17/12172 , A61B17/12177 , A61B2017/00867 , A61B2017/12095
摘要： Embodiments of the present invention are directed to occluder devices and methods for treating various target sites, such as the gonadal vein. For example, an occluder device according to one embodiment includes a tubular structure having proximal and distal ends and a preset, expanded configuration. The tubular structure is configured to be constrained to a reduced configuration for delivery to the target site and to at least partially return to the preset, expanded configuration within the target site when unconstrained. The preset, expanded configuration includes a plurality of expanded volume members and articulating members arranged in a repeating pattern with each articulating member coupling a pair of expanded volume members. In addition, at least one expanded volume member has a cross-sectional dimension that is larger than a cross-sectional dimension of a respective articulating member and that is at least as large as a cross-sectional dimension of the target site.
摘要翻译：本发明的实施例涉及用于治疗各种靶位点（例如性腺静脉）的封堵器装置和方法。例如，根据一个实施例的封堵器装置包括具有近端和远端以及预设的扩张构型的管状结构。管状结构被配置为被限制为减小配置以递送到目标部位，并且在不受约束时至少部分地返回到目标部位内的预设的扩展配置。预设的扩展配置包括多个膨胀的体积构件和以重复图案布置的铰接构件，每个铰接构件联接一对扩张的体积构件。此外，至少一个膨胀容积部件的横截面尺寸大于相应铰接件的横截面尺寸，并且至少与靶部位的横截面尺寸一样大。

9. 发明申请

WO2009042317A1 BRAIDED VASCULAR DEVICES HAVING NO END CLAMPS 审中-公开
标题翻译：具有无末端束的BRAIDED血管装置
公开(公告)号：WO2009042317A1
公开(公告)日：2009-04-02
申请号：PCT/US2008/073666
申请日：2008-08-20
申请人： AGA MEDICAL CORPORATION , ADAMS, Daniel, O. , PIGNATO, Paul
发明人： ADAMS, Daniel, O. , PIGNATO, Paul
IPC分类号： A61B17/08
CPC分类号： A61B17/12113 , A61B17/0057 , A61B17/12022 , A61B17/12036 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00615 , A61B2017/00623 , A61B2017/00867 , A61B2017/12054 , A61B2017/12095
摘要： In some embodiments, a medical device may include one or more of the following features: (a) a metal fabric formed of braided metal strands, (b) the medical device having a collapsed configuration for delivery through a channel in a patient's body and having a generally dumbbell-shaped expanded configuration with two expanded diameter portions separated by a reduced diameter portion formed between opposed ends of the device and unsecured metal strand ends at the opposed ends, and (d) a thrombogenic agent located on the metal fabric.
摘要翻译：在一些实施例中，医疗装置可以包括以下特征中的一个或多个：（a）由编织的金属线形成的金属织物，（b）医疗装置具有用于通过患者体内的通道递送的收缩构型，通常哑铃形的扩张构型具有两个扩展直径部分，该两个扩展直径部分由形成在装置的相对端部之间的直径减小的部分和在相对端处的不牢固的金属股末端分开，以及（d）位于金属织物上的血栓形成剂。

10. 发明申请

WO2009008868A1 PERCUTANEOUS CATHETER DIRECTED INTRAVASCULAR OCCLUSION DEVICES 审中-公开
标题翻译： PERCUTANEOUS导管指导性血管内装置
公开(公告)号：WO2009008868A1
公开(公告)日：2009-01-15
申请号：PCT/US2007/019347
申请日：2007-09-05
申请人： AGA MEDICAL CORPORATION , AMPLATZ, Kurt , GU, Xiaoping , OSLUND, John , ADAMS, Daniel, O.
发明人： AMPLATZ, Kurt , GU, Xiaoping , OSLUND, John , ADAMS, Daniel, O.
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12109 , A61B17/12122 , A61B17/12172 , A61B17/12177 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00628 , A61B2017/00632 , A61B2017/00867
摘要： The present invention provides an improved vascular occlusion device having improved flexibility and retention of the type fabricated from braided tubular metal fabric having an expanded preset configuration and an elongated collapsed reduced diameter configuration for delivery through a catheter to a treatment site and shaped to create an occlusion of an abnormal opening in a body organ or vessel, the woven metal fabric having a memory property whereby the medical device tends to return to said expanded preset configuration when unconstrained. The device further including at least one disk portion adjacent a body cylindrical portion formed from the fabric and having a transition diameter between the disk and cylindrical portion, significantly smaller than the diameter of the disk and the diameter of the cylindrical portion.
摘要翻译：本发明提供了一种改进的血管闭塞装置，其具有改进的由具有扩大的预设构型的编织管状金属织物制造的类型的柔性和保持性，以及用于通过导管输送到治疗部位并且成形以产生闭塞身体器官或血管中的异常开口，织造金属织物具有记忆特性，由此医疗装置在不受约束时趋向于返回到所述扩展的预设构型。所述装置还包括至少一个与所述织物形成的主体圆柱形部分相邻的圆盘部分，并且在所述圆盘和圆柱形部分之间具有明显小于所述圆盘直径和所述圆柱形部分直径的过渡直径。

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