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51. 发明申请

WO01000536A1 PROCESS AND APPARATUS FOR TREATING SOLID WASTE SLURRY 审中-公开
标题翻译：用于处理固体废料浆的方法和装置
公开(公告)号：WO01000536A1
公开(公告)日：2001-01-04
申请号：PCT/US2000/017815
申请日：2000-06-28
IPC分类号： B01D21/01 , C02F1/38 , C02F1/52
CPC分类号： C02F1/5281 , B01D21/01 , B01D21/10 , B01D21/2444 , B01D21/245 , B01D21/2472 , B01D21/26 , B01D21/262 , B01D21/267 , C02F1/38 , C02F1/52 , C02F1/5209
摘要： A process and apparatus (10) for the treament of a solid waste slurry formed from solid waste particles mixed with a liquid includes delivering a solid waste slurry to a first solid-liquid separation means (14) for separating a first amount of the solid waste particles from the slurry, followed by delivering the solid waste slurry from the first solid-liquid separation means (14) to a tank (22) where the solid waste slurry is stirred to maintain the solid waste particles in suspension. The solid waste slurry is then discharged from the tank (22) with a portion of the solid waste slurry being recirculated back to the tank (22) while a second portion of the solid waste slurry is delivered to a second solid-liquid separation means (50) for separating a second amount of the particles from the slurry. Following discontinuation of the stirring of the slurry, the liquid is decanted from the tank (22) at a level above a bottom area of the tank (22) with a discharge line (70), which includes a sampling line (84), in order to determine the amount of solid waste particles contained in the solid waste slurry. The decanting and sampling may be performed at additional levels with the tank (22) with discharge lines (72, 74) and sampling lines (88,92), respectively.
摘要翻译：用于由与液体混合的固体废物颗粒形成的固体废物浆料处理的方法和装置（10）包括将固体废物浆料输送到第一固体 - 液体分离装置（14），用于分离第一量的固体废物然后从第一固液分离装置（14）将固体废物浆料输送到搅拌固体废料浆料的罐（22），以保持固体废物颗粒处于悬浮状态。然后将固体废料浆料从罐（22）排出，其中固体废料浆料的一部分再循环回罐（22），而固体废料浆料的第二部分被输送到第二固液分离装置 50），用于从浆料中分离第二量的颗粒。在停止搅拌浆液之后，将液体从罐（22）的高度高于罐（22）的底部区域的水平处排出，其中排出管线（70）包括取样管线（84）以确定固体废物浆料中所含的固体废物颗粒的量。倾析和取样可以分别与具有排放管线（72,74）和采样管线（88,92）的罐（22）以额外的水平进行。

52. 发明申请

WO00061256A1 METHOD AND APPARATUS FOR PRODUCING PLATELET RICH PLASMA AND/OR PLATELET CONCENTRATE 审中-公开
标题翻译：用于生产富勒斯等离子体和/或电解质浓缩物的方法和装置
公开(公告)号：WO00061256A1
公开(公告)日：2000-10-19
申请号：PCT/US2000/008718
申请日：2000-04-11
IPC分类号： G01N33/48 , A61K35/14 , A61M1/02 , A61M1/36 , B01D21/26 , B04B5/02 , B04B5/04 , G01N33/49
CPC分类号： A61M1/0209 , A61M1/029 , A61M1/3693 , A61M2202/0415 , A61M2202/0427 , B01D21/262 , B01D2221/10 , B04B5/0421 , A61M2202/0092
摘要： Platelet rich plasma and/or platelet concentrate is prepared by placing whole blood in a first chamber (6) of a sterile processing disposable having two chambers (6, 8). The processing disposable is subjected to a first centrifugation to separate red blood cells (36), and the resulting platelet rich plasma supernatant (38) is decanted to the second chamber (8). The processing disposable is subjected to a second centrifugation to concentrate platelets. A volume of the platelet poor plasma supernatant in the second chamber (8) is removed, and the platelets are re-suspended in the remaining plasma. The second chamber (8) may contain anticoagulant (34) to preclude aggregation of the platelets.
摘要翻译：通过将全血放置在具有两个腔室（6,8）的无菌处理一次性的第一腔室（6）中来制备富血小板血浆和/或血小板浓缩物。对一次性处理进行第一次离心以分离红细胞（36），并将所得的富含血小板的血浆上清液（38）倾析到第二腔室（8）。对一次性处理进行第二次离心以浓缩血小板。除去第二腔室（8）中血小板不良血浆上清液的体积，并将血小板重新悬浮在剩余的血浆中。第二室（8）可以含有抗凝血剂（34）以排除血小板聚集。

53. 发明申请

WO00045931A1 APPARATUS FOR SEPARATING SOLIDS FROM OIL 审中-公开
标题翻译：从油中分离固体的装置
公开(公告)号：WO00045931A1
公开(公告)日：2000-08-10
申请号：PCT/GB2000/000148
申请日：2000-01-21
IPC分类号： B01D21/26 , B04B1/02 , B04B11/06 , B04B1/00 , B04B11/00
CPC分类号： B01D21/262 , B01D2221/02 , B04B1/02 , B04B11/06
摘要： Apparatus (10) for separating solids from oil comprises a housing (12) having a housing inlet (24) and a housing outlet (150). A rotatable drum spinner (50) has an inlet (116) and an outlet (57) at the opposite end thereof. A motor drives the spinner. A first pump (74) delivers oil to an inlet (112) of a second, disc, pump (120) concentric and rotatable with the spinner (50). The disc pump accelerates oil rotationally to the speed of rotation of the spinner and delivers the accelerated oil to the inlet of the spinner. Oil rotated by the spinner experiences centripetal acceleration so that denser particulate impurities (59) in the oil settle against the wall (58) of the spinner. Clean oil exist the spinner outlet an is directed therefrom to said housing outlet.
摘要翻译：用于从油中分离固体的装置（10）包括具有壳体入口（24）和壳体出口（150）的壳体（12）。可旋转滚筒旋转器（50）在其相对端具有入口（116）和出口（57）。电机驱动旋转器。第一泵（74）将油输送到与旋转器（50）同心并可旋转的第二盘式泵（120）的入口（112）。盘式泵将油旋转加速至旋转器的旋转速度，并将加速的油输送到旋转器的入口。由旋转器旋转的油经历向心加速度，使得油中更致密的颗粒杂质（59）抵靠旋转器的壁（58）。清洁油存在旋转出口a从其引导到所述壳体出口。

54. 发明申请

WO98030686A3 METHOD OF PURIFYING DNA IN A CROSS-FLOW CENTRIFUGE 审中-公开
标题翻译：在交叉流动离心中纯化DNA的方法
公开(公告)号：WO98030686A3
公开(公告)日：1998-09-11
申请号：PCT/EP1998/000104
申请日：1998-01-09
IPC分类号： C12N15/09 , B01D21/26 , C07H1/08 , C12N15/10
CPC分类号： B01D21/262 , B01D2221/10 , C12N15/1003
摘要： The invention concerns a method of purifying extrachromosomal DNA by passing an extrachromosomal DNA and fluid containing further cell components through a cross-flow centrifuge under given conditions, resulting in separation of the extrachromosomal DNA from the other cell components such that purified extrachromosomal DNA is obtained. The invention further concerns the use of the purified extrachromosomal DNA for cloning, transformation, transfection and microinjection into cells, for use in gene therapy processes, DNA vaccination and/or for polymerase chain reaction (PCR). The invention finally concerns the use of a cross-flow centrifuge for purifying extrachromosomal DNA.

55. 发明申请

WO1998018518A1 CELL SEPARATION DEVICE AND IN-LINE ORIFICE MIXER SYSTEM 审中-公开
标题翻译：细胞分离装置和在线混合器系统
公开(公告)号：WO1998018518A1
公开(公告)日：1998-05-07
申请号：PCT/US1997019704
申请日：1997-10-29
申请人： COHESION CORPORATION
发明人： COHESION CORPORATION , FREEMAN, Abigail , FULLER, Gerald, G. , SIERRA, David, H. , CONSTON, Stanley, R. , MICHAELS, Alan, S.
IPC分类号： A61M37/00
CPC分类号： B01D21/262 , B01D21/245 , B01D21/26 , B01D2221/10 , B01F5/0608 , B01F5/0688 , B01L3/5021
摘要： A fluid separation device and in-line orifice mixer system is disclosed. The fluid separation device utilizes a syringe (10), which is used for obtaining a fluid sample such as blood, in a centrifugation device; and further utilizes the syringe as a source of a separated fluid portion for storage and transfer for subsequent applications. The syringe containing the separated portion source, and a second syringe (50) containing a second source, are connected to the in-line orifice mixer device. The mixer device (44) comprises a plurality of orifice walls (58) each providing an orifice nonaligned with adjacent orifices to homogeneously mix the plurality of components. The mixer device may further comprise an exit orifice wall with one or more orifices for discharge of the homogeneous mixture.
摘要翻译：公开了一种流体分离装置和直列孔式混合器系统。流体分离装置在离心装置中使用用于获得诸如血液的流体样品的注射器（10）; 并且进一步利用注射器作为分离的流体部分的源，用于存储和转移用于随后的应用。包含分离部分源的注射器和包含第二源的第二注射器（50）连接到直列式孔混合器装置。混合器装置（44）包括多个孔壁（58），每个孔壁提供与相邻孔不对准的孔口以均匀地混合多个部件。混合器装置还可包括具有一个或多个用于排出均匀混合物的孔的出口孔壁。

56. 发明申请

WO1998010853A1 THIN, PLIABLE POLYMERIC FILM FOR SEALING MICROPLATES 审中-公开
标题翻译：薄膜，用于密封微胶囊的聚合物薄膜
公开(公告)号：WO1998010853A1
公开(公告)日：1998-03-19
申请号：PCT/US1997016296
申请日：1997-09-16
申请人： WHATMAN INC.
发明人： WHATMAN INC. , VALUS, Ronald, J. , LIPSKY, Johnathan, N.
IPC分类号： B01D21/26
CPC分类号： B01L3/5085 , B01D17/0217 , B01D17/044 , B01D17/085 , B01D21/0012 , B01D21/26 , B01D21/262 , B01D29/031 , B01D29/663 , B01D61/18 , B01L3/50255 , Y10T436/25375 , Y10T436/255
摘要： A sealing member for a multi-well microfiltration plate (10) comprises a flexible sealing material (20), which in response to the application of differential pressure, will flex or collapse in the direction of filtration along the contour of each individual well (12). A process maintains a differential pressure substantially constant over a multi-well microfiltration plate (10) comprising placing said flexible sealing member (20) over the surface of the multi-well microfiltration plate (10) having individual wells (12), stretching the flexible sealing member (20) so as to seal the perimeter of each individual well (12), creating a differential pressure around said multi-well microfiltration plate (10) covered with said flexible sealing material (20) and filtering a material (22) from each occupied well (12) at a rate independent of the filtration rate of any other well (12) while maintaining a substantially constant differential pressure around the multi-well microfiltration plate (10) until filtration in the last well (12) containing material (22) is complete.
摘要翻译：用于多孔微量过滤板（10）的密封构件包括柔性密封材料（20），其响应于施加压差而沿着每个单独孔（12）的轮廓在过滤方向上弯曲或塌缩）。一种工艺在多孔微量过滤板（10）上保持基本恒定的压差，包括将所述柔性密封构件（20）放置在具有各个孔（12）的多孔微量过滤板（10）的表面上，密封构件（20）以密封每个单独井（12）的周边，在由所述柔性密封材料（20）覆盖的所述多孔微量过滤板（10）周围产生差压，并将材料（22）从每个占据的井（12）以与任何其他井（12）的过滤速率无关的速率，同时在多孔微量过滤板（10）周围保持基本上恒定的差压，直到含有最终井（12）的材料 22）完成。

57. 发明申请

WO1997041064A1 CONCENTRATION OF SOLIDS IN THE BAYER PROCESS 审中-公开
标题翻译：固体在贝氏体过程中的浓度
公开(公告)号：WO1997041064A1
公开(公告)日：1997-11-06
申请号：PCT/US1997006631
申请日：1997-04-21
申请人： CYTEC TECHNOLOGY CORP.
发明人： CYTEC TECHNOLOGY CORP. , AVOTINS, V., Peter , RYLES, Roderick, G. , FLIEG, Gregory
IPC分类号： C01F07/06
CPC分类号： C01F7/0653 , B01D21/01 , B01D21/26 , B01D21/262 , C01F7/0646 , C22B21/0015 , Y02P10/234
摘要： Processes for improving solids/liquids separation efficiency in the Bayer process are disclosed, wherein Bayer process streams are treated with calcium or magnesium salts, flocculated with carboxylic acid or salt group-containing polymers, and centrifuged.
摘要翻译：公开了用于提高拜耳方法中固体/液体分离效率的方法，其中拜耳法处理物流用钙或镁盐处理，用羧酸或含盐基聚合物絮凝，并离心。

58. 发明申请

WO1997002094A1 SUGAR CENTRIFUGE WITH SCREEN PROTECTION 审中-公开
标题翻译：具有屏幕保护功能的糖果中心
公开(公告)号：WO1997002094A1
公开(公告)日：1997-01-23
申请号：PCT/US1996011009
申请日：1996-06-28
申请人： CALIFORNIA PELLET MILL COMPANY
发明人： CALIFORNIA PELLET MILL COMPANY , MILNER, Ted, D. , HUBALEK, Verne, A.
IPC分类号： B04B07/18
CPC分类号： B01D21/262 , B01D2221/06 , B04B3/00 , B04B7/18
摘要： In a continuous sugar centrifugal (10), an imperforate thin, open ended, truncated cone (26), of high strength corrosion-resistant material is placed on the working screen (22) within the centrifugal basket (20). The cone extends part way up the working screen and protects the working screen from damage from high impact particles being released from an accelerator bell (18).
摘要翻译：在连续的糖离心（10）中，将高强度耐腐蚀材料的无孔薄的开口的截头锥体（26）放置在离心筐（20）内的工作筛（22）上。锥体部分地延伸到工作屏幕上，并保护工作屏幕免受从加速器钟（18）释放的高冲击颗粒的损坏。

59. 发明申请

WO1996016714A1 METHOD AND DEVICE FOR SEPARATING FIBRIN MONOMER FROM BLOOD PLASMA 审中-公开
标题翻译：用于从血浆等离子体分离纤维素单体的方法和装置
公开(公告)号：WO1996016714A1
公开(公告)日：1996-06-06
申请号：PCT/US1995015669
申请日：1995-12-01
申请人： E.R. SQUIBB AND SONS, INC. , HOLM, Niels, Erik , EDWARDSON, Peter, Andrew, David
发明人： E.R. SQUIBB AND SONS, INC.
IPC分类号： B01D21/26
CPC分类号： G01N33/491 , A61M1/3693 , A61M1/3696 , A61M2202/0415 , A61M2202/0449 , A61M2202/045 , B01D21/01 , B01D21/08 , B01D21/20 , B01D21/2405 , B01D21/26 , B01D21/262 , B01D2221/10 , B04B5/0442 , B04B2005/0485 , Y10T436/111666 , Y10T436/25375
摘要： A device for separating components such as fibrin monomer from blood by centrifugation about a central axis comprising a first annular chamber (70) defined by an outer cylindrical wall (72) and an inner cylindrical wall (71) both walls being concentrically accommodated about an axis of rotation, and by a top wall (73) and a bottom wall (74), where the bottom wall is formed by a piston (55) displaceable within the first chamber. The device including a second chamber (75) below the first chamber and communicating with the first chamber through a first conduit (4) and being defined by said outer cylindrical wall (72), the bottom wall (74) of the first chamber, and another bottom wall (76). The device also includes a capsule (45) accommodated in the second chamber and including a plurality of compartments for receiving respective compositions promoting the separation.
摘要翻译：用于通过围绕包括由外圆柱形壁（72）和内圆柱形壁（71）限定的第一环形室（70））的中心轴离心分离诸如纤维蛋白单体的组分与血液的装置，所述两个壁围绕轴线同心地容纳的旋转，以及顶壁（73）和底壁（74），其中底壁由在第一室内可移位的活塞（55）形成。所述装置包括在第一室下方的第二室（75），并通过第一导管（4）与第一室连通并由所述外圆筒壁（72），第一室的底壁（74）限定，以及另一个底壁（76）。该装置还包括容纳在第二室中的胶囊（45），并且包括多个隔室，用于接收促进分离的相应组合物。

60. 发明申请

WO1996016713A1 CENTRIFUGE REAGENT DELIVERY SYSTEM 审中-公开
标题翻译：离心试剂递送系统
公开(公告)号：WO1996016713A1
公开(公告)日：1996-06-06
申请号：PCT/US1995015667
申请日：1995-12-01
申请人： E.R. SQUIBB AND SONS, INC. , HOLM, Niels, Erik
发明人： E.R. SQUIBB AND SONS, INC.
IPC分类号： B01D21/26
CPC分类号： B01D21/262 , B01D21/2405 , B01D21/2427 , B01D2221/10 , B04B1/02 , B04B5/0442 , B04B2005/0485 , Y10T137/87676 , Y10T436/111666 , Y10T436/25375
摘要： A device for separating components such as fibrin monomer from blood by centrifugation about a central axis comprising a first annular chamber (70) defined by an outer cylindrical wall (72) and an inner cylindrical wall (71) both walls being concentrically accommodated about an axis of rotation, and by a top wall (73) and a bottom wall (74), where the bottom wall is formed by a piston (55) displaceable within the first chamber. The device including a second chamber (75) below the first chamber and communicating with the first chamber through a first conduit (4) and being defined by the outer cylindrical wall (72), the bottom wall (74) of the first chamber, and another bottom wall (76). The device also includes a capsule (45) accommodated in the second chamber and including a plurality of compartments for receiving respective compositions promoting the separation.
摘要翻译：一种用于通过围绕包括由外圆柱形壁（72）和内圆柱形壁（71）限定的第一环形室（70））的中心轴离心分离诸如纤维蛋白单体的组分与血液的装置，两个壁围绕轴线同心地容纳的旋转，以及顶壁（73）和底壁（74），其中底壁由可在第一室内移位的活塞（55）形成。该装置包括在第一室下方的第二室（75），并通过第一导管（4）与第一室连通并由第二室的外圆筒壁（72），第一室的底壁（74）限定，以及另一个底壁（76）。该装置还包括容纳在第二室中的胶囊（45），并且包括多个隔室，用于接收促进分离的相应组合物。

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