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41. 发明申请

WO2004026174A3 EXPANDABLE MEDICAL DEVICE WITH OPENINGS FOR DELIVERY OF MULTIPLE BENEFICIAL AGENTS 审中-公开
标题翻译：具有用于输送多个受益人的开口的可扩展的医疗装置
公开(公告)号：WO2004026174A3
公开(公告)日：2004-08-12
申请号：PCT/US0329992
申请日：2003-09-22
申请人： CONOR MEDSYSTEMS INC , SHANLEY JOHN F
发明人： SHANLEY JOHN F
IPC分类号： A61F2/00 , A61F2/90 , A61L31/14 , A61L31/16 , A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0035 , A61F2250/0068 , A61L31/146 , A61L31/16 , A61L2300/416
摘要： An expandable medical device includes a plurality of elongated struts, forming a substantially cylindrical device which is expandable from a cylinder having a first diameter to a cylinder having a second diameter. A plurality of different beneficial agents can be loaded into different openings (30a, 30b) within the struts for delivery to the tissue. For treatment of specified conditions such as edge effect restenosis or for improved spacial distribution of the delivered beneficial agent, different beneficial agents are loaded into different openings in the device in a predefined pattern. The different beneficial agents may include one or more different drugs, the same drugs in different concentrations or with different erosion rates, or different forms of the same drug.
摘要翻译：可扩张医疗装置包括多个细长的支柱，形成基本上圆柱形的装置，其可从具有第一直径的圆柱体扩展到具有第二直径的圆柱体。多个不同的有益剂可以被装载到支柱内的不同的开口（30a，30b）中，以便输送到组织。为了治疗诸如边缘效应再狭窄的特定条件或为了改善递送的有益药物的空间分布，将不同的有益剂以预定图案装载到装置中的不同开口中。不同的有益药物可以包括一种或多种不同的药物，不同浓度或不同侵蚀速率的相同药物，或不同形式的相同药物。

42. 发明申请

WO2004056291A1 ENDOLUMENAL PROSTHESIS 审中-公开
公开(公告)号：WO2004056291A1
公开(公告)日：2004-07-08
申请号：PCT/IT2002/000813
申请日：2002-12-19
申请人： INVATEC S.R.L. , VENTURELLI, Andrea
发明人： VENTURELLI, Andrea
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558
摘要： An expandable endolumenal prosthesis (2) comprises, in the non-expanded configuration, a tubular body (3) extending along a longitudinal axis and having a distal end (4) and a proximal end (5), the tubular body having a porous wall defined by a plurality of interlaced circumferential lines (6) forming a pathway motif or pattern, in which each of the lines comprises at least one plurality of modules (7), each module comprises three lobes, that is, two outer lobes (8) and one inner lobe (9) disposed between the two outer lobes in the pathway of the pattern, both of the outer lobes of the three lobes being extended by straight outer arms (15), the at least one plurality of modules being arranged consecutively so as to have successive outer arms which extend from the outer lobes in substantially opposite directions relative to the pathway of the pattern for two successive modules, and in which, for each module, the distance (d1) between the apex of one of the outer lobes and the apex of the inner lobe of the same module is less than the distance (D2, D3) between the apex of the same outer lobe and the apex of any outer lobe of an adjoining module.
摘要翻译：可扩张腔内假体（2）以非膨胀构型包括沿着纵向轴线延伸并且具有远端（4）和近端（5）的管状主体（3），所述管状体具有多孔壁由形成通路基序或图案的多个隔行周向线（6）限定，其中每条线包括至少多个模块（7），每个模块包括三个叶，即两个外裂纹（8）和一个设置在所述图案的路径中的所述两个外凸角之间的内凸角（9），所述三个凸角的两个外凸角由直的外臂（15）延伸，所述至少一个多个模块被连续布置具有连续的外臂，其相对于两个连续模块的图案的路径以基本上相反的方向从外凸角延伸，并且其中对于每个模块，一个外凸角的顶点之间的距离（d1）和顶点同一组件的内凸角小于相同外凸角的顶点与相邻模块的任何外凸角的顶点之间的距离（D2，D3）。

43. 发明申请

WO2004028571A8 IMPLANTABLE STENT WITH MODIFIED ENDS 审中-公开
标题翻译：可修改的支架可植入支架
公开(公告)号：WO2004028571A8
公开(公告)日：2004-05-27
申请号：PCT/US0330902
申请日：2003-09-29
申请人： MEDLOGICS DEVICE CORP , PEACOCK JAMES C III , MAIER NATHAN CHRISTOPHER
发明人： PEACOCK JAMES C III , MAIER NATHAN CHRISTOPHER
IPC分类号： A61F2/00 , A61F2/82 , A61L
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/826 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2230/0013 , A61F2250/0035 , A61F2250/0067
摘要： A stent is provided with modified ends with unique local structures on the proximal end that provide for enhanced vessel-stent transition and enhanced drug delivery to the proximal "in-stent" vessel segment adjacent to the proximal stent end. A stent assembly is also provided for enhanced overlapping between adjacent stents for decreased thrombogenesis and restenosis.
摘要翻译：支架具有在近端处具有独特局部结构的改进端部，其提供增强的血管 - 支架转换并增强药物递送至邻近支架近端的近端“支架内”血管段。还提供支架组件以增强相邻支架之间的重叠以减少血栓形成和再狭窄。

44. 发明申请

WO2004026179A1 ANGULAR ORIENTATION OF A STENT 审中-公开
标题翻译：一个角度的角度定位
公开(公告)号：WO2004026179A1
公开(公告)日：2004-04-01
申请号：PCT/IL2003/000749
申请日：2003-09-17
申请人： ISRAEL, Henry
发明人： ISRAEL, Henry
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2250/0006 , A61F2250/0039 , A61F2250/006 , A61F2250/0098
摘要： A stent assembly comprising at least two markers located at different angular orientations on the stent assembly, the markers being discernible by an imaging device, wherein a projection of the at least two markers on an imaging plane uniquely defines an angle of rotation of the stent assembly about an axis thereof with respect to a reference.
摘要翻译：一种支架组件，其包括位于所述支架组件上的不同角度取向的至少两个标记，所述标记由成像装置识别，其中所述至少两个标记在成像平面上的突出部唯一地限定所述支架组件的旋转角度围绕其相对于基准的轴线。

45. 发明申请

WO2004016150A2 ANEURYSM STENT 审中-公开
公开(公告)号：WO2004016150A2
公开(公告)日：2004-02-26
申请号：PCT/US2003/025430
申请日：2003-08-15
申请人： THRAMANN, Jeffrey, M., D.
发明人： THRAMANN, Jeffrey, M., D. , FULTON, Michael, M., D.
IPC分类号： A61B
CPC分类号： A61F2/91 , A61B17/12022 , A61B17/12113 , A61B17/12136 , A61B17/12172 , A61B2017/00867 , A61B2017/1205 , A61B2017/12068 , A61F2/852 , A61F2/915 , A61F2/95 , A61F2/958 , A61F2002/30329 , A61F2002/30545 , A61F2002/30599 , A61F2002/826 , A61F2002/828 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91541 , A61F2002/91558 , A61F2002/91575 , A61F2002/91591 , A61F2002/9665 , A61F2220/0025 , A61F2230/0095 , A61F2250/001 , A61F2250/0063 , A61F2250/0071
摘要： The present invention relates to an aneurysm stent having a base and connector. The base has a vessel facing side and an aneurysm facing side, and is shaped to cover an aneurysm sufficiently. The connector is coupled to the aneurysm facing side of the base such that when deployed the connector is adapted to extend partially into the aneurysm to anchor the base about the aneurysm and inhibit flow into the aneurysm.
摘要翻译：本发明涉及具有基座和连接器的动脉瘤支架。基部具有面向血管的侧面和面向动脉瘤的侧面，并且被成形为充分覆盖动脉瘤。连接器联接到基部的面向动脉瘤侧，使得当展开时，连接器适于部分地延伸到动脉瘤中，以使基部围绕动脉瘤锚定并阻止流入动脉瘤。

46. 发明申请

WO2003077802A1 EXPANDABLE STENT HAVING INTERCONNECTED EXPANSION MODULES 审中-公开
标题翻译：具有互连扩展模块的可扩展性
公开(公告)号：WO2003077802A1
公开(公告)日：2003-09-25
申请号：PCT/US2003/007360
申请日：2003-03-11
申请人： STENT TECH, INC. , DAS, Gladwin, S.
发明人： DAS, Gladwin, S.
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/07 , A61F2/91 , A61F2/958 , A61F2002/91508 , A61F2002/91516 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2002/91566 , A61F2250/0098
摘要： Expandable stents are disclosed. The stents have a plurality of rings (112) or modules (112) interconnected in series, with selectable links (142’’) between the rings (112) to provide for articulation. The preferred stent includes a plurality of modules (112), each of the modules being radially interconnected to each other in series by respective interconnection bridges (142’’). Each ring (112) including a continuous strand of a material, the continuous strand of material being interconnected end to end so as to generally encompass a radial space within the ring (112). The strand of material being configured to include a repeating series of interconnected repeating W-shaped strand configurations (110) having a repeating dip (120), rise (122), dip (124), rise (126), loop (128), dip (130), rise (132), dip (134), rise (136), loop (138) patterned configuration.
摘要翻译：公开了可扩展支架。支架具有串联连接的多个环（112）或模块（112），在环（112）之间具有可选择的连接（142“），以提供铰接。优选的支架包括多个模块（112），每个模块通过相应的互连桥（142“）串联地彼此径向互连。每个环（112）包括材料的连续股，所述连续的材料股线端对端互连，以便大致包围所述环（112）内的径向空间。所述材料束构造成包括具有重复浸渍（120），上升（122），浸渍（124），上升（126），环（128）的重复的互连重复的W形股线构型（110）浸渍（130），上升（132），浸渍（134），上升（136），环（138）图案化构造。

47. 发明申请

WO2003059207A1 STENT 审中-公开
标题翻译：支架术
公开(公告)号：WO2003059207A1
公开(公告)日：2003-07-24
申请号：PCT/US2003/000179
申请日：2003-01-03
申请人： SCIMED LIFE SYSTEMS, INC
发明人： GIRTON, Timothy , GREGORICH, Daniel
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/915 , A61F2002/91508 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/91558 , A61F2002/91566 , A61F2002/91575
摘要： A stent comprises a plurality of circumferential bands. Circumferential bands which are adjacent one another are connected one to the other. The circumferential bands include first circumferential bands characterized by a first number of alternating first peaks and first troughs joined by bent struts and second circumferential bands characterized by a second number of alternating second peaks and second troughs joined by bent struts, the second number different from the first number.
摘要翻译：支架包括多个周向带。彼此相邻的环状带彼此连接。周向带包括第一周期带，其特征在于第一数量的交替的第一峰和通过弯曲支柱连接的第一槽和第二周向带，其特征在于第二数量的交替的第二峰和通过弯曲的支柱连接的第二槽，第一号码

48. 发明申请

WO2003022178A1 EXPANDABLE STENT 审中-公开
标题翻译：可扩展性
公开(公告)号：WO2003022178A1
公开(公告)日：2003-03-20
申请号：PCT/EP2002/009931
申请日：2002-09-05
申请人： CATHNET-SCIENCE HOLDING A/S , ANDERSEN, Erik , WEN, Ning
发明人： ANDERSEN, Erik , WEN, Ning
IPC分类号： A61F2/06
CPC分类号： A61F2/915 , A61F2/852 , A61F2/91 , A61F2002/826 , A61F2002/828 , A61F2002/91508 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2002/91591 , A61F2230/0013 , A61F2250/0063 , A61F2250/0068
摘要： An expandable stent comprising a tubular body made up of a plurality of separated tubular elements (1) arranged along a common longitudinal axis. Each tubular element (1) comprises a plurality of rhombic-shaped closed cell elements (2) joined by circumferentially extending linking members (3). The closed cell elements (2) are expandable to allow the tubular elements, and hence the stent itself, to expand. In the direction of the longitudinal axis of the stent, the extremities of each of the closed cell elements has an enlarged loop (30) with waisted portions (33) which allow the tubular elements to interlock to create a stable structure, at least when in the unexpanded condition.
摘要翻译：一种可扩张支架，其包括由沿着共同纵向轴线布置的多个分离的管状元件（1）构成的管状体。每个管状元件（1）包括通过周向延伸的连接件（3）连接的多个菱形闭孔元件（2）。闭孔元件（2）可膨胀以允许管状元件，因此支架本身膨胀。在支架的纵向轴线的方向上，每个闭合单元元件的末端具有带有腰部（33）的扩大的环（30），其允许管状元件互锁以产生稳定的结构，至少在未膨胀的条件。

49. 发明申请

WO02065949A3 LOCKING STENT 审中-公开
标题翻译：锁定杆
公开(公告)号：WO02065949A3
公开(公告)日：2002-11-28
申请号：PCT/US0203241
申请日：2002-02-06
申请人： SCIMED LIFE SYSTEMS INC
发明人： STENZEL ERIC B
IPC分类号： A61F2/00 , A61F2/06 , A61F2/90
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/30329 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2002/91558 , A61F2002/91566 , A61F2002/91591 , A61F2220/0025 , A61F2230/0013
摘要： A stent may be constructed to have at least one lockable cell which includes a first locking member and a second locking member. The first and second locking members are movable between a first position in which they are not locked together to a second position in which they are locked together and impart increased scaffolding strength to the stent.
摘要翻译：支架可被构造成具有至少一个可锁定单元，其包括第一锁定构件和第二锁定构件。第一和第二锁定构件可以在第一位置和第二位置之间移动，在第一位置中，第一和第二锁定构件未被锁定在第二位置，在第二位置中，它们被锁定在一起并且赋予支架增加的脚手架

50. 发明申请

WO2002067782A2 IMPLANT DELIVERY SYSTEM WITH INTERLOCK 审中-公开
标题翻译：具有互锁的植入式输送系统
公开(公告)号：WO2002067782A2
公开(公告)日：2002-09-06
申请号：PCT/US2002/003153
申请日：2002-02-01
申请人： INTRATHERAPEUTICS, INC.
发明人： THOMPSON, Paul, J. , LEE, Nathan, T.
IPC分类号： A61B17/00
CPC分类号： A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/91508 , A61F2002/91541 , A61F2002/91558 , A61F2002/91591 , A61F2002/9665 , A61F2220/005
摘要： An implant delivery system is disclosed. The delivery system includes an elongated member having an implant mounting location. A self-expandable implant is mounted at the implant mounting location. The implant is held in a compressed orientation by a retractable sheath. An interlock structure prevents the implant from deploying prematurely as the sheath is retracted.
摘要翻译：公开了一种植入物递送系统（10）。输送系统（10）包括具有植入物安装位置（26）的细长构件（14）。自扩张植入物（12）安装在植入物安装位置（26）处。植入物（12）通过可缩回护套（16）保持在压缩取向。当护套（16）缩回时，互锁结构（82,84）防止植入物（12）过早展开。

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