专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

31. 发明申请

WO2007106318A3 BIOCOMPATIBLE BONDING METHOD AND ELECTRONICS PACKAGE SUITABLE FOR IMPLANTATION 审中-公开
标题翻译：生物相容性粘结方法和适用于植入的电子装置
公开(公告)号：WO2007106318A3
公开(公告)日：2007-12-21
申请号：PCT/US2007004741
申请日：2007-02-22
申请人： SECOND SIGHT MEDICAL PROD INC , GREENBERG ROBERT J , OK JERRY
发明人： GREENBERG ROBERT J , OK JERRY
IPC分类号： A61N1/00
CPC分类号： A61N1/0543 , A61N1/36046 , A61N1/3752 , H01L23/057 , H01L23/10 , H01L23/4985 , H01L2224/05573 , H01L2224/16225 , H01L2224/73204 , H01L2224/92125 , H01L2924/01079 , H01L2924/1461 , H05K1/0306 , H05K3/321 , H05K3/328 , H05K3/361 , H05K3/4015 , H05K3/423 , H05K3/4652 , H05K3/4691 , H05K2201/09127 , H05K2201/10287 , H05K2201/10295 , H05K2201/10977 , H05K2203/0733 , H05K2203/1446 , H01L2924/00
摘要： The invention is directed to a method of bonding a hermetically sealed electronics package to an electrode or a flexible circuit and the resulting electronics package that is suitable for implantation in living tissue, such as for a retinal or cortical electrode array to enable restoration of sight to certain non-sighted individuals. The hermetically sealed electronics package is directly bonded to the flex circuit or electrode by electroplating a biocompatible material, such as platinum or gold, effectively forming a plated rivet-shaped connection, which bonds the flex circuit to the electronics package. The resulting electronic device is biocompatible and is suitable for long-term implantation in living tissue.
摘要翻译：本发明涉及一种将气密密封的电子器件封装结合到电极或柔性电路的方法，以及适合于植入活体组织（例如用于视网膜或皮层电极阵列）的所得电子封装，以使视线恢复某些不具视力的个人。通过电镀铂或金等生物相容性材料，将密封的电子组件直接接合到柔性电路或电极上，从而有效地形成电镀铆钉形连接，其将柔性电路结合到电子组件。由此产生的电子器件是生物相容性的，适用于长期植入活体组织。

32. 发明申请

WO2012158834A8 CORTICAL INTERFACE WITH AN ELECTRODE ARRAY DIVIDED INTO SEPARATE FINGERS AND/OR WITH A WIRELESS TRANSCEIVER 审中-公开
标题翻译：具有分离在独立手指和/或无线收发器中的电极阵列的光刻界面
公开(公告)号：WO2012158834A8
公开(公告)日：2013-07-18
申请号：PCT/US2012038200
申请日：2012-05-16
申请人： SECOND SIGHT MEDICAL PROD INC , GREENBERG ROBERT J , ZHOU DAVID DAOMIN , MECH BRIAN V , TALBOT NEIL HAMILTON , DAI RONGQING , CASTRO RICHARD AGUSTIN , MCCLURE KELLY
发明人： GREENBERG ROBERT J , ZHOU DAVID DAOMIN , MECH BRIAN V , TALBOT NEIL HAMILTON , DAI RONGQING , CASTRO RICHARD AGUSTIN , MCCLURE KELLY
IPC分类号： A61N1/05
CPC分类号： A61N1/36082 , A61B5/04001 , A61B5/4064 , A61B5/6868 , A61N1/0531 , A61N1/0534 , A61N1/0539 , A61N1/375 , H01L2224/05599 , H01L2224/45144 , H01L2224/48227 , H01L2224/48465 , H01L2224/85099 , H01L2224/85399 , H01L2924/3011 , H05K1/118 , H05K1/189 , H05K2201/0154 , H05K2201/10098 , H01L2924/00 , H01L2924/00014
摘要： The present application describes an implantable device with at least one package (214) that houses electronics that sends and receives data or signals, and optionally power, from an external system through at least one coil (216) attached to the at least one package and processes the data, including recordings of neural activity, and delivers electrical pulses to neural tissue through at least one array of multiple electrodes (210) attached to the at least one package. The device is intended to be installed in the head, or on or in the cranium or on the dura, or on or in the brain and is adapted to electrocorticographic (ECoG) and local field potential (LFP) signals.
摘要翻译：本申请描述了具有至少一个封装（214）的可植入装置，所述封装（214）容纳通过附接到所述至少一个封装件的至少一个线圈（216）从外部系统发送和接收数据或信号并且可选地供电的电子器件，以及处理数据，包括记录神经活动，并通过连接到至少一个包装的多个电极（210）的至少一个阵列将电脉冲传递给神经组织。该装置旨在安装在头部，或在头颅或硬脑膜上或脑中或脑中或脑中，并适用于皮质电图（ECoG）和局部场电位（LFP）信号。

33. 发明申请

WO2007035910A3 SUB-THRESHOLD STIMULATION TO PRECONDITION NEURONS FOR SUPRA-THRESHOLD STIMULATION 审中-公开
标题翻译：亚阈值刺激预先神经元用于SUPRA-THRESHOLD刺激
公开(公告)号：WO2007035910A3
公开(公告)日：2007-06-07
申请号：PCT/US2006036962
申请日：2006-09-19
申请人： SECOND SIGHT MEDICAL PROD INC
发明人： GREENBERG ROBERT J , MCMAHON MATTHEW J
IPC分类号： A61N1/00
CPC分类号： A61N1/36046 , A61N1/0543
摘要： In order to generate the smallest phosphenes possible, it is advantageous to selectively stimulate smaller cells. By hyperpolarizing the somas of the large cells selectively with sub-threshold anodic 'pre-pulse' stimuli (making them more difficult to stimulate) and then selectively depolarize the smaller cells one can selectively stimulate smaller cells. Alternatively, one can hyperpolarize the dendrites of the cells with larger dendritic fields by applying sub-threshold anodic currents on surrounding electrodes and then depolarizing the smaller cells in the center. Further, one can manipulate the phases of an individual biphasic wave to affect selective stimulation resulting in more focal responses. It is possible to increase resolution with the 'pre-pulse' described above. One can also effect resolution by modifying the pulse order of the cathodic and anodic phases. Further, one can isolate the effect of the phases by separating them in time (long inter-phase interval) or by making one of the phases long and low amplitude - always keeping equal total charge for the two phases. As an example, one can preferentially stimulate smaller ganglion cells by providing a longer sub-threshold anodic pulse balanced with a shorter supra-threshold cathodic pulse. Preferentially stimulating the smaller ganglion cells will allow stimulation of different brightness levels while maintaining high spatial resolution.
摘要翻译：为了产生尽可能最小的光幻视，选择性刺激较小的细胞是有利的。通过使亚阈值阳极“预脉冲”刺激选择性超极化大细胞的体细胞（使其更难以刺激），然后选择性地使较小细胞去极化，可选择性刺激较小细胞。或者，通过在周围电极上施加亚阈值阳极电流，然后使中心的较小细胞去极化，可以使具有较大树突状细胞的细胞的树突超极化。此外，可以操纵单个双相波的相位以影响选择性刺激，导致更多的局部反应。通过上述“预脉冲”可以提高分辨率。也可以通过修改阴极和阳极相的脉冲次数来实现分辨率。此外，可以通过及时分离相位（长相间间隔）或通过使相位中的一个较长和较低振幅来隔离相位的影响 - 总是保持两相的总电荷相等。作为一个例子，可以通过提供较长的亚阈值阳极脉冲和较短的超阈值阴极脉冲来优先刺激较小的神经节细胞。优先刺激较小的神经节细胞将允许刺激不同的亮度水平，同时保持高空间分辨率。

34. 发明申请

WO0056244A2 LOGARITHMIC LIGHT INTENSIFIER FOR USE WITH PHOTORECEPTOR-BASED IMPLANTED RETINAL PROSTHETICS AND THOSE PROSTHETICS 审中-公开
标题翻译：使用基于光电离子的植入物前体和这些前体的对数光增强器
公开(公告)号：WO0056244A2
公开(公告)日：2000-09-28
申请号：PCT/US0005753
申请日：2000-03-03
申请人： SECOND SIGHT LLC , GREENBERG ROBERT J , SEIDMAN ABRAHAM N , SCHULMAN JOSEHPH H
发明人： GREENBERG ROBERT J , SEIDMAN ABRAHAM N , SCHULMAN JOSEHPH H
IPC分类号： A61F9/007 , A61F2/14 , A61F2/48 , A61N1/36 , A61F
CPC分类号： A61N1/36046 , A61F9/08
摘要： The invention is for directly modulating a beam of photons (102) onto the retinas of patients who have extreme vision impairment or blindness. The purpose is to supply sufficient imaging energy (108) to retinal prosthetics implanted in the eye which operates essentially by having light (external to the eye) activating photoreceptor. The invention supplies light amplification logarithmical (3).
摘要翻译：本发明用于将光束（102）直接调节到具有极端视力障碍或失明的患者的视网膜上。目的是为植入眼睛的视网膜假体提供足够的成像能量（108），其基本上通过使光（外部的外部）活化感光体。本发明提供光放大对数（3）。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式