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31. 发明申请

WO2009133557A2 METHODS AND APPARATUSES FOR SELECTING A BOLUS DELIVERY PATTERN IN A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于选择药物递送装置中的胶体递送图案的方法和装置
公开(公告)号：WO2009133557A2
公开(公告)日：2009-11-05
申请号：PCT/IL2009000453
申请日：2009-04-28
申请人： MEDINGO LTD , YODFAT OFER , GESCHEIT IDDO M , SHAPIRA GALI
发明人： YODFAT OFER , GESCHEIT IDDO M , SHAPIRA GALI
IPC分类号： G06F19/00
CPC分类号： A61M5/1723 , A61M5/14248 , A61M2205/3569 , A61M2205/3592 , A61M2205/502 , A61M2205/52 , A61M2230/201 , G06F19/3468
摘要： Methods, systems and devices for sustained medical infusion of fluids are described. Some implementations describe portable infusion methods, systems and devices for selecting a pattern of fluid delivery. Some implementations describe skin securable insulin dispensing methods, systems and devices for selecting a delivery pattern according to the nutritional characteristics (e.g. glycemic index, GI, fat content, etc.) of caloric intake of the user.
摘要翻译：描述了用于持续医学输注流体的方法，系统和装置。一些实施方案描述了用于选择流体递送模式的便携式输注方法，系统和装置。一些实施方案描述了皮肤可固化的胰岛素分配方法，系统和装置，用于根据使用者的热量摄取的营养特征（例如血糖指数，GI，脂肪含量等）来选择递送模式。

32. 发明申请

WO2009056981A3 RECIPROCATING DELIVERY OF FLUIDS TO THE BODY WITH ANALYTE CONCENTRATION MONITORING 审中-公开
标题翻译：使用分析物浓度监测往返输送流体到身体
公开(公告)号：WO2009056981A3
公开(公告)日：2009-08-13
申请号：PCT/IB2008003357
申请日：2008-05-07
申请人： MEDINGO LTD , YODFAT OFER , KAIDAR RUTHY , SHAPIRA GALI
发明人： YODFAT OFER , KAIDAR RUTHY , SHAPIRA GALI
IPC分类号： A61B5/00 , A61M5/172
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/150022 , A61B5/150229 , A61B5/150389 , A61B5/150503 , A61B5/157 , A61B5/4839 , A61B5/6848 , A61B2560/0412 , A61B2560/0443 , A61M5/14248 , A61M5/1723 , A61M2005/1726
摘要： A volume of an analyte-enriched fluid can be withdrawn out of a user's subcutaneous compartment using a patch unit that includes a reversible pumping mechanism. The volume can be withdrawn out of the body and into the patch unit through a cannula inserted into the subcutaneous compartment so that an analyte concentration in the volume can be measured using a sensing element within the patch unit. After analyte concentration analysis, at least the volume can be delivered back into the subcutaneous compartment by operating the pumping mechanism in a forward direction, biologically compatible fluid can optionally be pumped into the subcutaneous compartment from a reservoir in the patch unit and then allowed to partially or completely equilibrate with the analyte concentration in the interstitial fluid of the subcutaneous compartment via a permeable or semi-permeable cannula surface before being drawn back into the patch unit for analysis. Related systems, apparatus, methods, and/or articles are also described.
摘要翻译：可以使用包括可逆泵送机构的贴片单元将体积的富含分析物的流体从用户的皮下隔室中抽出。可通过插入皮下隔室的套管将体积抽出体外并进入贴片单元，从而可使用贴片单元内的感测元件测量体积中的分析物浓度。在分析物浓度分析之后，通过沿向前方向操作泵送机构，至少该体积可以被递送回到皮下隔室中，生物兼容性流体可以任选地从贴片单元中的贮存器泵入皮下隔室，然后允许部分或者在被吸回到贴片单元中用于分析之前经由可渗透或半可渗透的套管表面与皮下隔室的间质液中的分析物浓度完全平衡。还描述了相关的系统，装置，方法和/或物品。

33. 发明申请

WO2016181384A3 SYSTEMS, APPARATUSES AND METHODS FOR FLUID INFUSION INTO A BODY 审中-公开
标题翻译：流体输送到体内的系统，装置和方法
公开(公告)号：WO2016181384A3
公开(公告)日：2017-02-09
申请号：PCT/IL2016050481
申请日：2016-05-05
申请人： TRIPLE JUMP ISRAEL LTD , YODFAT OFER , SHINAR GUY , BEN-DAVID YISHAI
发明人： YODFAT OFER , SHINAR GUY , BEN-DAVID YISHAI
IPC分类号： A61M5/142 , A61M5/145 , A61M5/168
CPC分类号： A61M5/16831 , A61M5/1407 , A61M5/14244 , A61M5/1723 , A61M2005/14284 , A61M2005/16863 , A61M2205/18 , A61M2205/33 , A61M2205/3584 , A61M2205/50 , A61M2205/8206 , A61M2230/201
摘要： [0120] Embodiments of the current disclosure are directed toward systems, devices and methods for diabetes management. In particular, the present disclosure relates to devices and methods for dispensing insulin to a patient. A portable fluid infusion device, comprising a disposable part (DP) and a reusable part (RP) is disclosed. The DP comprises a first reservoir and a second reservoir, the second reservoir less than or equal to the first reservoir in length, while the RP comprises a first compartment configured to receive the first reservoir, a second compartment configured to receive the second reservoir and a gasket for sealing a junction between the second reservoir and the second compartment upon connection of the RP and the DP.
摘要翻译：本公开的实施例涉及用于糖尿病管理的系统，装置和方法。具体地，本公开涉及用于将胰岛素分配给患者的装置和方法。公开了一种包括一次性部件（DP）和可重复使用部件（RP）的便携式流体输注装置。 DP包括第一储存器和第二储存器，第二储存器小于或等于第一储存器的长度，而RP包括构造成容纳第一储存器的第一隔室，被配置为容纳第二储存器的第二隔室和垫圈，用于在RP和DP连接时密封第二储存器和第二隔室之间的接合点。

34. 发明申请

WO02055124A3 SYSTEM AND CORRESPONDING METHOD FOR DEPLOYING AN IMPLANTABLE INTRALUMINAL DEVICE 审中-公开
标题翻译：系统和部署可植入式内腔器械的相应方法
公开(公告)号：WO02055124A3
公开(公告)日：2002-11-21
申请号：PCT/IL0200023
申请日：2002-01-11
申请人： MINDGUARD LTD , HARARI ERAN , GRAD YGAEL , YODFAT OFER
发明人： HARARI ERAN , GRAD YGAEL , YODFAT OFER
IPC分类号： A61F2/82 , A61F2/06 , A61F2/84 , A61M25/00 , A61M25/12 , A61M25/10
CPC分类号： A61F2/958
摘要： System and corresponding method for optimally deploying an implantable expandable intraluminal device (20) at the required location in a body lumen (30), featuring an outer tube (28), at least one inner tube (25) located inside and co-axial (24) with the outer tube, an expandable balloon (26) mounted on the at least one inner tube, and, a pair of socks (27). The balloon and the pair of socks are situated at an extremity of the at least one inner tube, whereby extremity of each sock overlaps an edge of the expandable device when in a contracted state, and, whereby the extremity of each sock becomes axially spaced from the corresponding edge when the expandable device is in an at least partially expanded state.
摘要翻译：系统和对应的方法，用于在体腔（30）中的所需位置处优化地布置可植入式可扩张腔内装置（20），其特征在于外管（28），至少一个内管（25）位于内部并且同轴 24）与所述外管，安装在所述至少一个内管上的可膨胀球囊（26）以及一对袜子（27）。气囊和一对袜子位于至少一个内管的末端，由此每个袜子的末端在处于收缩状态时与可扩张装置的边缘重叠，并且由此每个袜子的末端变得与当可扩张装置处于至少部分扩张状态时的对应边缘。

35. 发明申请

WO0205729A3 IMPLANTABLE BRAIDED STROKE PREVENTING DEVICE AND METHOD OF MANUFACTURING 审中-公开
标题翻译：可植入式编织行程预防装置和制造方法
公开(公告)号：WO0205729A3
公开(公告)日：2002-06-13
申请号：PCT/IL0100624
申请日：2001-07-09
申请人： MIND GUARD LTD , YODFAT OFER , GRAD YGAEL
发明人： YODFAT OFER , GRAD YGAEL
IPC分类号： A61B17/00 , A61F20060101 , A61F2/00 , A61F2/01 , A61F2/84 , A61F2/90 , A61L31/00 , A61M1/02 , A61M29/02 , A61F2/06
CPC分类号： A61F2/90 , A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2230/0078 , A61F2250/0015 , A61F2250/0039
摘要： An implantable deflecting device for positioning in the vicinity of an arterial bifurcation for causing embolic material flowing toward a first branch of the bifurcation to be deflected into the second branch of the same bifurcation. The device comprises a deflecting filtering element suitable to deflect the flow of embolic material flowing toward said second branch, while filtering the blood flowing toward said first branch. The device comprising a braided tubular body having a contracted state with a first diameter, and an expanded state having a second diameter greater than said first diameter.
摘要翻译：一种用于定位在动脉分叉附近的可植入的偏转装置，用于使得朝分叉的第一分支流动的栓塞材料偏转进入同一分叉的第二分支。该装置包括偏转过滤元件，该偏转过滤元件适于偏转流向所述第二分支的栓塞材料的流动，同时过滤流向所述第一分支的血液。该装置包括具有第一直径的收缩状态的编织管状体和具有大于所述第一直径的第二直径的扩张状态。

36. 发明申请

WO2016181384A9 SYSTEMS, APPARATUSES AND METHODS FOR FLUID INFUSION INTO A BODY 审中-公开
标题翻译：用于将流体输入体内的系统，装置和方法
公开(公告)号：WO2016181384A9
公开(公告)日：2017-03-30
申请号：PCT/IL2016050481
申请日：2016-05-05
申请人： TRIPLE JUMP ISRAEL LTD , YODFAT OFER , SHINAR GUY , BEN-DAVID YISHAI
发明人： YODFAT OFER , SHINAR GUY , BEN-DAVID YISHAI
IPC分类号： A61M5/142 , A61M5/145 , A61M5/168
CPC分类号： A61M5/16831 , A61M5/1407 , A61M5/14244 , A61M5/1723 , A61M2005/14284 , A61M2005/16863 , A61M2205/18 , A61M2205/33 , A61M2205/3584 , A61M2205/50 , A61M2205/8206 , A61M2230/201
摘要： [0120] Embodiments of the current disclosure are directed toward systems, devices and methods for diabetes management. In particular, the present disclosure relates to devices and methods for dispensing insulin to a patient. A portable fluid infusion device, comprising a disposable part (DP) and a reusable part (RP) is disclosed. The DP comprises a first reservoir and a second reservoir, the second reservoir less than or equal to the first reservoir in length, while the RP comprises a first compartment configured to receive the first reservoir, a second compartment configured to receive the second reservoir and a gasket for sealing a junction between the second reservoir and the second compartment upon connection of the RP and the DP.
摘要翻译：本公开的实施例针对用于糖尿病管理的系统，设备和方法。具体而言，本公开涉及用于将胰岛素分配给患者的装置和方法。公开了一种便携式流体输注装置，其包括一次性部分（DP）和可再用部分（RP）。 DP包括第一储存器和第二储存器，第二储存器的长度小于或等于第一储存器，而RP包括配置成接收第一储存器的第一隔室，配置成接收第二储存器的第二隔室和用于在RP和DP连接时密封第二储存器和第二隔室之间的接合处。

37. 发明申请

WO2009013637A2 METHOD AND DEVICE FOR ASSESSING CARBOHYDRATE-TO-INSULIN RATIO 审中-公开
标题翻译：用于评估碳水化合物与胰岛素比率的方法和装置
公开(公告)号：WO2009013637A2
公开(公告)日：2009-01-29
申请号：PCT/IB2008003185
申请日：2008-06-20
申请人： MEDINGO HEADQUARTERS , YODFAT OFER , SHAPIRA GALI , GESCHEIT IDDO M
发明人： YODFAT OFER , SHAPIRA GALI , GESCHEIT IDDO M
CPC分类号： A61B5/14503 , A61B5/0002 , A61B5/14532 , A61B5/4839 , A61B5/6849 , A61B2562/0295 , A61K38/28 , A61M5/14248 , A61M5/1723 , A61M2005/14208 , A61M2005/14268 , A61M2005/1726 , A61M2205/3569 , A61M2205/3592 , G01N33/66 , G16H50/20
摘要： A system and a method for determining an assessed carbohydrate to insulin ratio of a patient is described. The system and the method can comprise a memory component adapted for storing an initial set of values comprising at least one of a blood glucose level, a target blood glucose level, an insulin sensitivity, and, an estimated carbohydrate to insulin ratio. The system and the method can also comprise a bolus selection component adapted for selecting a test bolus corresponding to the determined initial set of values and a planned meal. In one implementation, the bolus selection component can receive bolus dose input from a user, hi another implementation, the bolus selection component can estimate the bolus dose using a set of available inputs (e.g. the amount of carbohydrates in the planned meal). The system and the method can further comprise a user interface component adapted for receiving a confirmation that the test bolus has been administered to the patient. In some implementations, the user interface component can be adapted for selecting a meal of a known content.
摘要翻译：描述了用于确定患者的评估的碳水化合物与胰岛素的比率的系统和方法。该系统和方法可以包括适于存储包括血糖水平，目标血糖水平，胰岛素敏感度和估计的碳水化合物与胰岛素比率中的至少一个的初始值组的存储器组件。该系统和方法还可以包括推注选择部件，该推注选择部件适用于选择对应于所确定的初始值组和计划进餐的测试推注。在一个实施方式中，推注选择组件可以接收来自用户的推注剂量输入。在另一个实施方式中，推注选择组件可以使用一组可用输入（例如，计划进餐中的碳水化合物的量）来估计推注剂量。该系统和方法可以进一步包括用户界面组件，该用户界面组件适于接收测试推注已经被施用于患者的确认。在一些实现中，用户界面组件可以适用于选择已知内容的用餐。

38. 发明申请

WO2004050137A3 BRAIDED INTRALUMINAL DEVICE FOR STROKE PREVENTION 审中-公开
公开(公告)号：WO2004050137A3
公开(公告)日：2005-02-10
申请号：PCT/IL0301013
申请日：2003-11-28
申请人： MINDGUARD LTD , YODFAT OFER , NISHRI BOAZ , GRAD YGAEL , RAPAPORT AVRAHAM , OZ ORNA , ASSAF YARON , HARRIS DAGAN
发明人： YODFAT OFER , NISHRI BOAZ , GRAD YGAEL , RAPAPORT AVRAHAM , OZ ORNA , ASSAF YARON , HARRIS DAGAN
IPC分类号： A61M20060101 , A61M29/00
CPC分类号： A61F2/01 , A61F2002/018 , A61F2230/0006 , A61F2230/0069 , A61F2250/0039
摘要： A diverting filter (100) for implantation in the bifurcation of the human common carotid artery (CCA) with the external carotid artery (ECA) and the internal carotid artery (ICA), comprising: a tubular body expandable from an initial small-diameter state for manipulation through the CCA to an expanded larger-diameter state for implantation in said bifurcation, the tubular body having an at rest state wherein the tubular body exhibits a diameter greater than the expanded larger-diameter state; the tubular body including a proximal region (120) for implantation in the CCA, a distal region (130) for implantation in the ECA, and a middle filtering region (110) for alignment with the orifice of the ICA for diverting relatively-large emboli in the CCA blood flow to the ECA while minimizing interference to blood flow through both the ICA and the ECA; constituted of between 48 and 56 braided filaments exhibiting an average porosity index of at least 80%.
摘要翻译：一种用于植入在具有颈外动脉（ECA）和颈内动脉（ICA）的人颈总动脉（CCA）的分叉中的转向过滤器（100），包括：可从初始小直径状态为了通过CCA操纵到用于植入所述分叉的扩大的较大直径状态，管状体具有静止状态，其中管状体的直径大于扩大的大直径状态; 所述管体包括用于注入所述CCA的近端区域（120），用于植入所述ECA中的远侧区域（130）和用于与所述ICA的孔口对准的中间过滤区域（110），用于转移相对较大的栓塞在CCA血液流向非洲经委会的同时，尽量减少通过ICA和非洲经委会对血流的干扰; 由48和56个编织长丝构成，其显示平均孔隙率指数至少为80％。

39. 发明申请

WO03043527A2 IMPLANTABLE INTRALUMINAL DEVICE AND METHOD OF USING SAME IN TREATING ANEURYSMS 审中-公开
标题翻译：可植入的内窥镜装置及其在治疗神经系统中的使用方法
公开(公告)号：WO03043527A2
公开(公告)日：2003-05-30
申请号：PCT/IL0200886
申请日：2002-11-06
申请人： MINDGUARD LTD , YODFAT OFER , LIEBER BARUCH , GRAD YGAEL , NISHRI BOAZ
发明人： YODFAT OFER , LIEBER BARUCH , GRAD YGAEL , NISHRI BOAZ
IPC分类号： A61F2/06 , A61F2/82 , A61F2/90 , A61F
CPC分类号： A61F2/90 , A61F2/07 , A61F2/82 , A61F2002/065 , A61F2002/068 , A61F2002/821 , A61F2002/823 , A61F2250/0023 , Y10S623/909
摘要： An intraluminal device implantable in a blood vessel having an aneurysm therein in the vicinity of a perforating vessel and/or of a bifurcation leading to a branch vessel. The intraluminal device includes a mesh-like tube of bio-compatible material having an expanded condition in which the tube diameter is slightly larger than the diameter of the blood vessel in which it is to be implanted, and the tube length is sufficient to straddle the aneurysm and to be anchored to the blood vessel on the opposite sides of the aneurysm. The mesh-like tube also has a contracted condition wherein it is sufficiently flexible so as to be easily manipulatable through the blood vessel to straddle the aneurysm. In its expanded condition, the mesh-like tube has a porosity index of 55% - 80% such as to reduce the flow of blood through its wall to the aneurysm sufficiently to decrease the possibility of rupture of the aneurysm but not to unduly reduce the blood flow to a perforating or branch vessel to the degree likely to cause significant damage to tissues supplied with blood by such perforating or branch vessel.
摘要翻译：可在植入血管的血管内的管腔内装置，其中具有穿孔容器附近的动脉瘤和/或通向分支血管的分叉。管腔内装置包括具有膨胀状态的生物相容性材料的网状管，其中管直径略大于待植入的血管的直径，并且管长度足以跨越动脉瘤，并被锚定到动脉瘤相对侧的血管。网状管还具有收缩状态，其中其具有足够的柔性，以便通过血管易于操纵以跨越动脉瘤。在其膨胀状态下，网状管具有55％-80％的孔隙率指数，以减少血液通过其壁到动脉瘤的流动，足以降低动脉瘤破裂的可能性，但不会不适当地减少血液流动到穿孔或分支血管，其程度可能会对由这种穿孔或分支血管供血的组织造成严重损害。

40. 发明申请

WO0053119A8 IMPLANTABLE STROKE PREVENTING DEVICE 审中-公开
标题翻译：可植入防护装置
公开(公告)号：WO0053119A8
公开(公告)日：2001-06-07
申请号：PCT/IL0000147
申请日：2000-03-09
申请人： MINDGUARD LTD , YASSOUR YUVAL , YODFAT OFER , GRAD YGAEL , ROSENFELD MOSHE , LEVIN DANIEL
发明人： YASSOUR YUVAL , YODFAT OFER , GRAD YGAEL , ROSENFELD MOSHE , LEVIN DANIEL
IPC分类号： A61F2/00 , A61F2/01 , A61F2/04 , A61F2/06 , A61F2/84 , A61F2/90
CPC分类号： A61F2/90 , A61F2/01 , A61F2/04 , A61F2/856 , A61F2/954 , A61F2/958 , A61F2002/016 , A61F2002/018 , A61F2002/061 , A61F2002/065 , A61F2002/068 , A61F2230/0006 , A61F2230/0069 , A61F2250/0017 , A61F2250/0024
摘要： An implantable device (20) for positioning in the vicinity of the bifurcation of the common carotid artery (CCA) (38) into the internal carotid artery (ICA) (40) and the external carotid artery (ECA) (42) comprises a deflecting element (24) suitable to deflect the flow (60) of embolic material flowing in the CCA (38) toward the ICA (40), into the ECA (42).
摘要翻译：用于定位在颈总动脉（CCA）（38）的分叉附近进入颈内动脉（ICA）（40）和外颈动脉（ECA）（42））附近的可植入装置（20）包括偏转适于将流过CCA（38）的栓塞物流的流（60）朝向ICA（40）偏转的元件（24）进入ECA（42）。

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