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31. 发明申请

WO2008084477A3 IN-SITU FILTER 审中-公开
标题翻译：现场过滤器
公开(公告)号：WO2008084477A3
公开(公告)日：2010-02-04
申请号：PCT/IL2008000038
申请日：2008-01-08
申请人： GROSS YOSSI , GOLDSTEIN DANIEL
发明人： GROSS YOSSI , GOLDSTEIN DANIEL
IPC分类号： A61M29/00 , C12Q1/02
CPC分类号： A61F2/01 , A61F2230/0006 , A61N5/062
摘要： Apparatus is provided including a filter (30) configured for placement into a body of a patient, in a vicinity of a site including cancerous tissue (28). The filter (30) comprises an attachment surface (34) configured to capture particles (26) administered to treat the tissue (28). Other embodiments are also described.
摘要翻译：提供了包括被配置为放置在患者体内，包括癌组织（28）的位置附近的过滤器（30）的装置。过滤器（30）包括构造成捕获施用以处理组织（28）的颗粒（26）的附接表面（34）。还描述了其它实施例。

32. 发明申请

WO2005074384A3 EXTRACARDIAC BLOOD FLOW AMPLIFICATION DEVICE 审中-公开
标题翻译：提取液血液放大装置
公开(公告)号：WO2005074384A3
公开(公告)日：2009-09-03
申请号：PCT/IL2005000177
申请日：2005-02-10
申请人： GROSS YOSSI
发明人： GROSS YOSSI
IPC分类号： A61N1/362
CPC分类号： A61F2/02 , A61F2002/068 , A61M1/1008 , A61M1/1037 , A61M1/106 , A61M1/1072 , A61M1/1096 , A61M1/122
摘要： Apparatus (10) is provided including a first chamber (20) and a second chamber (22), adapted to be in fluid communication with a first volume and a second volume of oxygenated blood of a subject, respectively, the first chamber (20) and the second chamber (22) having a first surface (34) and a second surface (36), respectively. The apparatus (10) further includes a third surface (38) adapted to apply an elastically-derived force, at least a first portion of the third surface (38) in mechanical communication with the first surface (34), and at least a second portion of the third surface (38) in mechanical communication with the second surface (36) during at least a portion of a cardiac cycle. A pressure-sensitive valve (46) is coupled between the first chamber (20) and the second chamber (22), the valve (46) adapted: (a) to be in an open position during at least a portion of systole, such that the first chamber (20) is in fluid communication with the second chamber (22) and the first volume is in fluid communication with the second volume; and (b) to be in a substantially closed position during diastole, such that the first chamber (20) is substantially not in fluid communication with the second chamber (22) and the first volume is substantially not in fluid communication with the second volume. Other embodiments are also described.
摘要翻译：提供了装置（10），其包括第一室（20）和第二室（22），其适于分别与受试者的第一体积和第二体积的含氧血液流体连通，第一室（20）并且所述第二室（22）分别具有第一表面（34）和第二表面（36）。所述设备（10）还包括适于施加弹性导出力的第三表面（38），所述第三表面（38）的至少第一部分与所述第一表面（34）机械连通，并且至少第二表面所述第三表面（38）的部分在心动周期的至少一部分期间与所述第二表面（36）机械连通。压敏阀（46）联接在第一室（20）和第二室（22）之间，阀（46）适于：（a）在至少一部分收缩期间处于打开位置，所述第一室（20）与所述第二室（22）流体连通，并且所述第一容积与所述第二容积流体连通; 和（b）在舒张期间处于基本上闭合的位置，使得第一腔室（20）基本上不与第二腔室（22）流体连通，并且第一容积基本上不与第二容积流体连通。还描述了其它实施例。

33. 发明申请

WO2005065044A3 PRESSURE-PROPELLED SYSTEM FOR BODY LUMEN 审中-公开
标题翻译：用于体温的压力推进系统
公开(公告)号：WO2005065044A3
公开(公告)日：2006-07-27
申请号：PCT/IL2005000008
申请日：2005-01-03
申请人： G I VIEW LTD , CABIRI OZ , GROSS YOSSI , DEGTIAR BORIS , SHOR ERAN
发明人： CABIRI OZ , GROSS YOSSI , DEGTIAR BORIS , SHOR ERAN
IPC分类号： A61M29/00 , A61B1/00 , A61B1/012 , A61B1/015 , A61B1/05
CPC分类号： A61B1/012 , A61B1/00082 , A61B1/00147 , A61B1/00156 , A61B1/015 , A61B1/05 , A61B1/31
摘要： Apparatus is provided for use with a biologically-compatible-fluid pressure source, the apparatus including an elongate carrier, adapted to be inserted through a proximal opening of a body lumen, and a piston head coupled to a distal portion of the carrier. The piston head is adapted to form a pressure seal with a wall of the lumen after the carrier has been inserted into the lumen, and to be advanced distally through the body lumen in response to pressure from the fluid pressure source. The apparatus is configured to facilitate distal advancement of the piston head by facilitating passage of fluid out of the lumen from a site within the lumen distal to the piston head. The apparatus additionally includes an optical system, coupled to the carrier in a vicinity of the distal portion, the optical system having distal and proximal ends.
摘要翻译：提供了与生物相容流体压力源一起使用的装置，该装置包括适于插入通过体腔的近侧开口的细长载体和联接到载体的远端部分的活塞头。活塞头适于在载体已经插入内腔之后与内腔的壁形成压力密封，并且响应于来自流体压力源的压力而向远侧远端推进通过体腔。该装置被配置为通过促使流体从内腔远离活塞头的内部位置流出管腔来促进活塞头的远端前进。该装置还包括光学系统，该光学系统在远端部分附近耦合到载体，该光学系统具有远端和近端。

34. 发明申请

WO2005105053A3 ACTIVE DRUG DELIVERY IN THE GASTROINTESTINAL TRACT 审中-公开
标题翻译：活性药物在胃肠道手术中的输送
公开(公告)号：WO2005105053A3
公开(公告)日：2006-05-18
申请号：PCT/IL2005000301
申请日：2005-03-16
申请人： PILL PHARMA LTD E , GROSS YOSSI , SELA YORAM , BELSKY ZIV , LEV RINA , GOLDSTEIN DANIEL
发明人： GROSS YOSSI , SELA YORAM , BELSKY ZIV , LEV RINA , GOLDSTEIN DANIEL
IPC分类号： A61K9/22 , A61B1/05 , A61B5/00 , A61B5/03 , A61B5/07 , A61B17/32 , A61B18/02 , A61B18/14 , A61B18/20 , A61B19/00 , A61J3/07 , A61K9/00 , A61K9/48 , A61M31/00 , A61N1/05 , A61N1/30 , A61N1/32 , A61N1/36 , A61N1/372 , A61N1/375 , G01K13/00
CPC分类号： A61B1/041 , A61B1/00016 , A61B1/00156 , A61B5/0008 , A61B5/01 , A61B5/036 , A61B5/073 , A61B5/14532 , A61B5/14539 , A61B5/14546 , A61B5/4839 , A61B17/3203 , A61B18/02 , A61B18/14 , A61B18/20 , A61B34/70 , A61B34/72 , A61J3/07 , A61K9/0004 , A61K9/0009 , A61K9/0097 , A61K9/4808 , A61M31/002 , A61N1/05 , A61N1/306 , A61N1/325 , A61N1/327 , A61N1/36007 , A61N1/3605 , A61N1/37205 , A61N1/3756 , G01K13/002
摘要： Apparatus (30) for drug administration is provided, including an ingestible capsule (32), which includes a drug (36), stored by the capsule (32), and an environmentally-sensitive mechanism (18), adapted to change a state thereof responsively to a disposition of the capsule (32) within a gastrointestinal (GI) tract (50) of a subject. The capsule (32) further includes first and second electrodes (16), and a control component (14), adapted to facilitate passage of the drug (36), in response to a change of state of the environmentally-sensitive mechanism (18), through an epithelial layer of the GI tract (50) by driving the first and second electrodes (16) to apply a series of pulses at a current of less than about 10 mA, at a frequency of between about 12 Hz and about 24 Hz, and with a pulse duration of between about 0.5 milliseconds and about 3 milliseconds. Other embodiments are also described.
摘要翻译：提供了用于药物给药的装置（30），包括可吸收胶囊（32），其包括由胶囊（32）储存的药物（36）和适于改变其状态的环境敏感性机构（18）响应于胶囊（32）在受试者的胃肠（GI）道（50）内的布置。胶囊（32）还包括响应于环境敏感机构（18）的状态改变而适于促进药物（36）通过的第一和第二电极（16）和控制部件（14）通过驱动第一和第二电极（16）通过GI道（50）的上皮层以约12Hz至约24Hz的频率施加小于约10mA的电流的一系列脉冲并且脉冲持续时间在约0.5毫秒至约3毫秒之间。还描述了其它实施例。

35. 发明申请

WO2011151830A3 GASTRIC ANCHOR 审中-公开
标题翻译：气管锚
公开(公告)号：WO2011151830A3
公开(公告)日：2016-05-19
申请号：PCT/IL2011000433
申请日：2011-06-02
申请人： RAINBOW MEDICAL LTD , GROSS YOSSI
发明人： GROSS YOSSI
IPC分类号： A61M31/00
CPC分类号： A61M25/04 , A61K9/0065 , A61M31/002 , A61N1/0551 , A61N1/36007
摘要： A swallowable medical treatment device (10) is configured to initially assume a contracted state having a volume of less than 4 cm3. The device (10) includes a gastric anchor (20), which initially assumes a contracted size, and which is configured to, upon coming in contact with a liquid, expand sufficiently to prevent passage of the gastric anchor (20) through a round opening (28) having a diameter of between 1 cm and 3 cm. The device (10) also includes a duodenal unit (22), which is configured to pass through the opening (28), which is coupled to the gastric anchor (20), and which includes one or more elongated members (96), each of which has a length of at least 1 cm, and which are configured to expand upon coming in contact with a duodenal liquid. Other embodiments are also described.
摘要翻译：可吞咽的医疗装置（10）构造成最初承担体积小于4cm 3的收缩状态。装置（10）包括胃锚（20），其最初承受缩小尺寸，并且构造成在与液体接触时充分膨胀以防止胃锚（20）通过圆形开口（28），其直径在1cm和3cm之间。装置（10）还包括十二指肠单元（22），其被配置为穿过联接到胃锚（20）的开口（28），并且包括一个或多个细长构件（96），每个其长度为至少1cm，并且构造成在与十二指肠液体接触时膨胀。还描述了其它实施例。

36. 发明申请

WO2012120495A3 TISSUE TREATMENT AND MONITORING BY APPLICATION OF ENERGY 审中-公开
标题翻译：通过应用能源组织治疗和监测
公开(公告)号：WO2012120495A3
公开(公告)日：2015-06-18
申请号：PCT/IL2012000100
申请日：2012-03-04
申请人： RAINBOW MEDICAL LTD , GROSS YOSSI , KARDOSH MICHAEL , MEIRY GIDEON , TSOREF LIAT , KUSHKULEY LEONID , ASSAF YARON
发明人： GROSS YOSSI , KARDOSH MICHAEL , MEIRY GIDEON , TSOREF LIAT , KUSHKULEY LEONID , ASSAF YARON
IPC分类号： A61B18/04
CPC分类号： A61N7/022 , A61B5/4836 , A61B8/12 , A61B8/445 , A61B8/546 , A61B2017/22069 , A61B2018/00404 , A61B2018/00434 , A61B2018/00511 , A61B2018/00577 , A61N2007/0043 , A61N2007/0078 , A61N2007/0086 , A61N2007/0091
摘要： Apparatus is provided, which includes at least one ultrasound transducer. The ultrasound transducer is configured to be positioned within a lumen of a subject and to ablate tissue surrounding a wall of the lumen without ablating the wall of the lumen, by focusing ultrasound energy on a focal zone that is outside of the wall of the lumen. A transluminal delivery tool is configured to position the ultrasound transducer in the lumen, and a control unit is configured to drive the ultrasound transducer. Other embodiments are also described.
摘要翻译：提供了包括至少一个超声换能器的装置。超声换能器被配置为定位在受试者的内腔内，并且通过将超声能量聚焦在位于管腔壁外部的聚焦区域上而消融内腔壁周围的组织，而不会消融内腔壁。经腔递送工具被配置为将超声换能器定位在内腔中，并且控制单元被配置为驱动超声换能器。还描述了其它实施例。

37. 发明申请

WO2013035092A3 WIRELESS ENDOVASCULAR STENT-BASED ELECTRODES 审中-公开
标题翻译：无电极基底静脉电极
公开(公告)号：WO2013035092A3
公开(公告)日：2015-04-16
申请号：PCT/IL2012000336
申请日：2012-09-09
申请人： ENOPACE BIOMEDICAL LTD , DAGAN AMIR , ELAZAR MOSHE , HANANI NITAI , ARIAV GAL , MEIRI ODED , GINDIN IGOR , BERNSHTEIN VADIM , ARMONY NIR , GROSS YOSSI , REISNER YOTAM , GLASBERG OFFER
发明人： DAGAN AMIR , ELAZAR MOSHE , HANANI NITAI , ARIAV GAL , MEIRI ODED , GINDIN IGOR , BERNSHTEIN VADIM , ARMONY NIR , GROSS YOSSI , REISNER YOTAM , GLASBERG OFFER
IPC分类号： A61F2/06
CPC分类号： A61N1/40 , A61B5/0215 , A61B5/04 , A61B5/0402 , A61B5/0816 , A61F2/82 , A61F2/915 , A61F2002/8483 , A61F2002/91541 , A61F2002/91558 , A61F2220/0016 , A61F2220/005 , A61F2220/0075 , A61F2230/0054 , A61F2250/0002 , A61F2250/0018 , A61N1/05 , A61N1/0514 , A61N1/0558 , A61N1/056 , A61N1/057 , A61N1/36053 , A61N1/3756 , A61N2001/0585
摘要： Apparatus and methods are provided for use with a blood vessel of a subject, including a stent (20) configured to be placed in the blood vessel. The stent includes at least first (32), second (34), and third (36) strut portions disposed along the stent. The first and second strut portions are coupled to one another at a first junction (37A) that facilitates bending of the first and second strut portions with respect to one another. The second and third strut portions are coupled to one another at a second junction (37B) that facilitates bending of the second and third strut portions with respect to one another. At least one electrode (22) is disposed on at least an outer surface of the stent. Other applications are also described.
摘要翻译：提供了与被检体的血管一起使用的装置和方法，包括构造成放置在血管中的支架（20）。所述支架包括沿支架设置的至少第一（32），第二（34）和第三（36）支柱部分。第一和第二支柱部分在促进第一和第二支柱部分相对于彼此的弯曲的第一接合部（37A）处彼此联接。第二和第三支柱部分在促进第二和第三支柱部分相对于彼此弯曲的第二接合部（37B）处彼此联接。至少一个电极（22）设置在支架的至少外表面上。还描述了其它应用。

38. 发明申请

WO2013021375A3 PERCUTANEOUS MITRAL VALVE REPLACEMENT AND SEALING 审中-公开
标题翻译： PERCUTANEOUS MITRAL VALVE替代和密封
公开(公告)号：WO2013021375A3
公开(公告)日：2013-06-06
申请号：PCT/IL2012000293
申请日：2012-08-05
申请人： MITRALTECH LTD , GROSS YOSSI , HACOHEN GIL , MILLER ERAN , ZIPORY YUVAL , REICH TAL , KUTZIK MEIR , NEEMAN ROTEM
发明人： GROSS YOSSI , HACOHEN GIL , MILLER ERAN , ZIPORY YUVAL , REICH TAL , KUTZIK MEIR , NEEMAN ROTEM
IPC分类号： A61B17/10 , A61B17/04 , A61B17/12 , A61F2/24
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2220/0016 , A61F2230/0054 , A61F2230/0078 , A61F2250/006
摘要： For some applications, apparatus is provided for facilitating implantation of a prosthetic valve (150) at a native heart valve (120) of a subject, the apparatus comprising a prosthetic valve support (22), the prosthetic valve support (a) being configured to be transluminally-deliverable to the native valve and to be deployable at the native valve, and (b) comprising one or more tissue-engaging elements (24), configured to couple the prosthetic valve support to leaflets (128) of the native valve without eliminating check valve functionality of the native valve. Other embodiments are also described.
摘要翻译：对于一些应用，提供了一种用于便于在受试者的天然心脏瓣膜（120）处植入人造瓣膜（150）的装置，所述装置包括人造瓣膜支撑件（22），所述假性瓣膜支撑件（a）被配置为可自动递送到天然瓣膜并且可在天然瓣膜处展开，以及（b）包括一个或多个组织接合元件（24），其构造成将所述假体瓣膜支撑件连接到所述天然瓣膜的叶片（128），而没有消除了本机阀的止回阀功能。还描述了其它实施例。

39. 发明申请

WO2012085907A2 PACEMAKER WITH NO PRODUCTION 审中-公开
标题翻译：没有生产的PACEMAKER
公开(公告)号：WO2012085907A2
公开(公告)日：2012-06-28
申请号：PCT/IL2011000952
申请日：2011-12-20
申请人： RAINBOW MEDICAL LTD , GROSS YOSSI , DAGAN AMIR , REISNER YOTAM , GLASBERG OFFER , HANANI NITAI , ARIAV GAL
发明人： GROSS YOSSI , DAGAN AMIR , REISNER YOTAM , GLASBERG OFFER , HANANI NITAI , ARIAV GAL
IPC分类号： A61N1/365 , A61N1/362
CPC分类号： A61N1/3627 , A61N1/36542 , A61N1/368
摘要： Apparatus and methods are provided for use with a heart of a subject, including a set of one or more electrodes (28). A control unit (16) paces the heart by driving a first electric current via the electrode set into tissue of the subject, in accordance with a first set of parameters. The control unit stimulates nitric oxide production by a portion of the heart by driving a second electric current via the electrode set into the portion of the heart, in accordance with a second set of parameters. Other embodiments are also described.
摘要翻译：提供了与受试者的心脏一起使用的装置和方法，包括一组一个或多个电极（28）。根据第一组参数，控制单元（16）通过将经由电极组的第一电流驱动到对象的组织中而使心脏跳动。根据第二组参数，控制单元通过经由电极组的第二电流驱动心脏的一部分来刺激一部分心脏的一氧化氮产生。还描述了其它实施例。

40. 发明申请

WO2012073240A2 BORING ELEMENT FOR SELECTIVE BORING 审中-公开
标题翻译：选择镗孔的镗孔元件
公开(公告)号：WO2012073240A2
公开(公告)日：2012-06-07
申请号：PCT/IL2011000919
申请日：2011-12-01
申请人： GROSS YOSSI , GELBER MOSHE , AMIT NOAH , ALON RUTH
发明人： GROSS YOSSI , GELBER MOSHE , AMIT NOAH , ALON RUTH
IPC分类号： A61C3/02
CPC分类号： A61C1/084 , A61B17/1626 , A61B2017/00026 , A61B2017/00106 , A61C3/02 , A61C19/04
摘要： Apparatus and methods are provided for use with a first portion of a subject's body, the first portion being adjacent to a second portion of the subject's body. A boring element (20) is configured to bore a hole through the first portion of the subject's body. A housing (31) houses the boring element, the housing being shaped to accommodate and at least partially surround the first and second portions of the subject's body. A sensor (25) is coupled to the boring element and is configured to sense a parameter in a vicinity of the distal end of the boring element. A control unit (26) is configured to terminate the boring of the boring element in response to the sensed parameter indicating that the distal end of the boring element is in a vicinity of the second portion.
摘要翻译：提供了与被摄体的第一部分一起使用的装置和方法，第一部分与受试者身体的第二部分相邻。镗孔元件（20）被配置为穿过被检体的第一部分的孔。壳体（31）容纳钻孔元件，壳体被成形为容纳并且至少部分地围绕被检者的身体的第一和第二部分。传感器（25）联接到钻孔元件并且被配置成感测钻孔元件的远端附近的参数。控制单元（26）被配置为响应于感测到的参数来终止钻孔元件的钻孔，该参数指示钻孔元件的远端在第二部分附近。

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