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21. 发明申请

WO2007083310A2 SYSTEM AND METHOD FOR ANALYSIS AND TREATMENT OF A BODY TISSUE 审中-公开
标题翻译：一种身体组织分析和治疗的系统和方法
公开(公告)号：WO2007083310A2
公开(公告)日：2007-07-26
申请号：PCT/IL2007/000071
申请日：2007-01-18
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil
发明人： HASHIMSHONY, Dan , COHEN, Gil
IPC分类号： A61B5/05
CPC分类号： A61B5/05 , A61B1/04 , A61B10/0041 , A61B10/0275 , A61B17/320068 , A61B18/24 , A61B18/245 , A61B2017/00022 , A61B2017/00026 , A61B2017/00061 , A61B2017/00084 , A61B2017/00106 , A61B2017/00809
摘要： The invention provides a system and method for analysis and treatment of a tissue site. The system of the invention includes a probe unit containing one or more tissue sensing and monitoring probes configured to measure one or more parameters indicative of one or more states of the tissue site and one or more tissue treatment probes configured to deliver a treatment to the tissue site. A processor receives signals from the sensing and monitoring probes and determines whether the probe unit is located at the tissue site to be treated. The treatment and monitoring probes are activated in order to monitor the state of the tissue site while the treatment is being delivered to the tissue site. The processor receives signals from the sensing and monitoring probes during delivery of the treatment indicative of the state of the tissue site and determines, as the treatment is being carried out, any one or more of whether the treatment carried out so far is adequate, whether an additional treatment needs to be carried out, and whether the parameters of the treatment or the treatment targets need to be modified.
摘要翻译：本发明提供了用于分析和治疗组织部位的系统和方法。本发明的系统包括探针单元，其包含一个或多个组织感测和监测探针，所述组织感测和监测探针被配置成测量指示组织部位的一个或多个状态的一个或多个参数，以及被配置为将组织处理递送到组织的一个或多个组织治疗探针现场。处理器从感测和监测探头接收信号，并确定探针单元是否位于要治疗的组织部位。激活治疗和监测探针以便在治疗被递送到组织部位时监测组织部位的状态。在处理指示组织部位状态的处理期间，处理器接收来自感测和监测探针的信号，并且确定正在进行处理的任何一个或多个是否足以进行处理需要进行额外的治疗，以及是否需要修改治疗或治疗目标的参数。

22. 发明申请

WO2007015255A2 TISSUE-CHARACTERIZATION PROBE WITH EFFECTIVE SENSOR-TO-TISSUE CONTACT 审中-公开
标题翻译：具有有效传感器组织接触的组织特征探针
公开(公告)号：WO2007015255A2
公开(公告)日：2007-02-08
申请号：PCT/IL2006/000908
申请日：2006-08-06
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A01H5/00
CPC分类号： A61B6/032 , A61B5/0059 , A61B5/015 , A61B5/0536 , A61B5/055 , A61B5/103 , A61B5/4312 , A61B5/6834 , A61B5/6843 , A61B5/6844 , A61B5/6885 , A61B5/6886 , A61B6/4417 , A61B6/5247 , A61B8/13
摘要： A device for substance-characterization, designed for effective sensor-to-substance contact, includes an element, having a rigid surface, on which at least one sensor is arranged, and a mechanism for causing a force to be applied to a soft, pliable substance, the line of force being at a sharp angle with the rigid surface, for stretching or stretching and pushing the soft substance against the rigid surface, thus achieving effective contact between the substance and the at least one sensor. In consequence, the accuracy of the sensing is improved. In accordance with another embodiment, a plurality of sensors is employed, arranged along a curved element, for providing three-dimensional information regarding the substance, for example, by small-scale computerized tomography. Alternatively, the device comprises a structure; a first mechanism, configured for exerting a first force on a substance, for fixing the substance to the structure, so as to substantially immobilize the substance; and a second mechanism, configured for pressing at least one sensor against an external surface of the immobilized substance, thereby exerting a second force on the immobilized substance, wherein at least a component of the first force is in opposition to at least a component of the second force, forcing the immobilized substance against the at least one sensor, and forcing the at least one sensor against the immobilized substance, bringing about an effective contact between the at least one sensor and the immobilized substance. The substance may be tissue, ex-vivo or in situ, or a biopsy sample. Alternatively, it may be another soft, pliable substance, such as hydrogel or an elastomer.
摘要翻译：用于物质表征的用于有效的传感器到物质接触的装置包括具有刚性表面的元件，至少一个传感器布置在该刚性表面上，以及用于使力施加到软的，柔韧的物质，力线与刚性表面成锐角，用于拉伸或拉伸并将软物质推靠在刚性表面上，从而实现物质与至少一个传感器之间的有效接触。因此，传感的精度得到改善。根据另一个实施例，采用多个传感器，沿着弯曲元件布置，用于提供关于物质的三维信息，例如通过小规模计算机断层摄影。或者，该装置包括一个结构; 第一机构，被配置为对物质施加第一力，用于将物质固定到结构体上，以便基本上固定物质; 以及第二机构，其被配置为将至少一个传感器压靠在所述固定化物质的外表面上，从而对所述固定化物质施加第二力，其中所述第一力的至少一部分与所述固定化物质的至少一部分相对，迫使所述固定化物质抵靠所述至少一个传感器，并迫使所述至少一个传感器抵靠所述固定化物质，从而在所述至少一个传感器和所述固定化物质之间产生有效的接触。物质可以是组织，离体或原位或活组织检查样品。或者，它可以是另一种软的，柔韧的物质，例如水凝胶或弹性体。

23. 发明申请

WO2002071133A2 FIBER OPTICAL ATTENUATOR 审中-公开
标题翻译：光纤光衰
公开(公告)号：WO2002071133A2
公开(公告)日：2002-09-12
申请号：PCT/IL2002/000188
申请日：2002-03-08
申请人： XTELLUS INC. , COHEN, Gil
发明人： COHEN, Gil
IPC分类号： G02F1/01
CPC分类号： G02F1/1326 , G02B6/266 , G02F1/0115 , G02F1/134309 , G02F1/1396 , G02F1/2955 , G02F2201/04 , G02F2201/17 , G02F2203/48
摘要： A fiber optical attenuator utilizing the cut-off phenomenon for single mode propagation of an optical wave down a single mode fiber, comprising an element such as a pixelated liquid crystal element, capable of spatially changing the phase across the cross section of an input optical signal. Such a spatial phase change is equivalent to a change in the mode structure of the propagating wave. The signal propagating in the single mode output fiber is attenuated in accordance with the extent to which higher order modes are mixed into the low order mode originally present. When the mode is completely transformed to higher order modes, the wave is effectively completely blocked from entering the output single-mode fiber, and the attenuation is high. The level of attenuation is determined by the fraction of the wave which is converted to modes other than the lowest order mode, and is thus controllable by the voltage applied to the pixels of the liquid crystal element.
摘要翻译：一种光纤衰减器，其利用用于单模光纤单模传播的截止现象的光纤衰减器，其包括诸如像素化液晶元件的元件，能够在输入光信号的横截面上空间改变相位。这样的空间相位变化相当于传播波的模式结构的变化。在单模输出光纤中传播的信号根据最初存在的低阶模式混合到高阶模式的程度而衰减。当模式完全转换为高阶模式时，波被有效完全阻止进入输出单模光纤，衰减高。衰减的水平由转换成除了最低阶模式之外的模式的波的分数确定，并且因此可以通过施加到液晶元件的像素的电压来控制。

24. 发明申请

WO2009150647A2 DOUBLE REGISTRATION 审中-公开
标题翻译：双重登记
公开(公告)号：WO2009150647A2
公开(公告)日：2009-12-17
申请号：PCT/IL2009/000577
申请日：2009-06-10
申请人： DUNE MEDICAL DEVICES LTD. , COHEN, Gil , HASHIMSHONY, Dan
发明人： COHEN, Gil , HASHIMSHONY, Dan
IPC分类号： A61B19/00
CPC分类号： A61B19/5244 , A61B34/20 , A61B2034/2068 , A61B2034/2072 , A61B2090/363 , A61B2090/3908
摘要： A mapping system including: (a) at least one external marker adapted for positioning outside a target to define a target context; (b) at least one target marker adapted for positioning with the target; (c) a data acquisition tool configured to provide position coordinates for at least one data point at the target; and (d) a registration module adapted to output position coordinates of said at least one data point relative to at least a portion of the target context.
摘要翻译：一种映射系统，包括：（a）适于定位在目标外部以定义目标上下文的至少一个外部标记; （b）适于与靶标定位的至少一个目标标记; （c）数据采集工具，被配置为提供所述目标处的至少一个数据点的位置坐标; 以及（d）注册模块，其适于相对于所述目标上下文的至少一部分输出所述至少一个数据点的位置坐标。

25. 发明申请

WO2008132750A1 CLEAN MARGIN ASSESSMENT TOOL 审中-公开
标题翻译：清洁评估工具
公开(公告)号：WO2008132750A1
公开(公告)日：2008-11-06
申请号：PCT/IL2008/000594
申请日：2008-05-01
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/05 , A61B8/08 , A61B5/00 , A61B5/053 , A61B5/055 , A61B5/06 , A61B8/12
CPC分类号： A61B5/0507 , A61B5/0062 , A61B5/0071 , A61B5/0075 , A61B5/0084 , A61B5/0086 , A61B5/0091 , A61B5/015 , A61B5/053 , A61B5/055 , A61B5/065 , A61B5/415 , A61B5/4312 , A61B5/4381 , A61B8/4245
摘要： A device is provided for use in monitoring a tissue. The device is configured for holding and characterizing a tissue portion during the monitoring. The device comprises a housing configured for receiving and holding the tissue portion by an inner side or an outer side of the housing; and a tissue-type sensor unit mounted on either one or both of the inner and outer sides of the housing and configured and operable for characterizing the tissue portion being held by the housing.
摘要翻译：提供了一种用于监测组织的装置。该装置被配置为在监视期间保持和表征组织部分。该装置包括构造成用于通过壳体的内侧或外侧容纳和保持组织部分的壳体; 以及组装型传感器单元，其安装在所述壳体的内侧和外侧的一侧或两侧，并被构造和可操作以表征由所述壳体保持的所述组织部分。

26. 发明申请

WO2008132714A2 ERGONOMIC PROBES 审中-公开
标题翻译：人格探索
公开(公告)号：WO2008132714A2
公开(公告)日：2008-11-06
申请号：PCT/IL2008/000406
申请日：2008-03-24
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B5/00 , B25G3/38 , A61B6/00 , A61B8/00 , A61B19/00
CPC分类号： A61B5/4312 , A61B5/00 , A61B5/0055 , A61B5/0059 , A61B5/01 , A61B5/053 , A61B5/055 , A61B5/444 , A61B5/445 , A61B6/00 , A61B6/037 , A61B6/4417 , A61B8/00 , A61B8/12 , A61B8/445 , A61B8/4455 , A61B90/30 , A61B2090/395 , A61B2560/0425 , B25G1/06 , B25G1/102
摘要： An ergonomic device for intraoperative tissue characterization is provided, having a gripping handle and a sensor head, arranged with an angle alpha between them, wherein in absolute value, alpha > 10 degrees, and alpha may be adjusted in one, two, or three planes. The device may further comprise a light fixture, configured for lighting the tissue, as it is characterized, a marking module, configured for marking the tissue, as it is characterized, a vacuum system, for improved contact between a sensing surface and the tissue, and a transparent frame, which enables an operator to observe the tissue, as it is characterized. The device may be operative with at least one sensor, selected from the group consisting of an optical sensor, an X-ray sensor, an RF sensor, a MW sensor, an infrared thermography sensor, an ultrasound sensor, an MR sensor, an impedance sensor, a temperature sensor, a biosensor, a chemical sensor, a radioactive-emission sensor, a nonirradiative RF sensor, and a mechanical sensor.
摘要翻译：提供了一种用于术中组织表征的符合人体工程学的装置，其具有夹紧手柄和传感器头部，其间以它们之间的角度α布置，其中绝对值为α> 10度，并且可以在一个，两个或三个平面中调整α 。该装置可进一步包括配置用于照亮组织的灯具，其特征在于，标记模块被构造成用于标记组织，其特征在于，真空系统用于改善感测表面和组织之间的接触，以及透明框架，其使得操作者能够观察组织的特征。该装置可以与至少一个传感器一起操作，该传感器选自光学传感器，X射线传感器，RF传感器，MW传感器，红外热像传感器，超声波传感器，MR传感器，阻抗传感器，温度传感器，生物传感器，化学传感器，放射性发射传感器，非辐射RF传感器和机械传感器。

27. 发明申请

WO2008072238A2 GRAPHICAL USER INTERFACES (GUI), METHODS AND APPARATUS FOR DATA PRESENTATION 审中-公开
标题翻译：图形用户界面（GUI），数据呈现的方法和装置
公开(公告)号：WO2008072238A2
公开(公告)日：2008-06-19
申请号：PCT/IL2007/001539
申请日：2007-12-12
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , YARDEN, Orit , AHARONOWITZ, Gal , COHEN, Gil
发明人： HASHIMSHONY, Dan , YARDEN, Orit , AHARONOWITZ, Gal , COHEN, Gil
IPC分类号： G06F19/00
CPC分类号： G06F19/321 , G06F19/00 , G16H10/20
摘要： A graphical user interface (GUI) including: (a) a group definition module adapted to accept a user input defining groups; (b) a data receiver operable to receive a plurality of individual measurement input datum indicative of status of a substrate; (c) a grouping module configured to assign each of said individual measurement input datum to one of said groups to produce grouped data; and (d) an output module adapted to output the grouped data.
摘要翻译：一种图形用户界面（GUI），包括：（a）适合于接受定义组的用户输入的组定义模块; （b）数据接收器，用于接收指示衬底状态的多个单独的测量输入数据; （c）分组模块，其被配置为将每个所述个体测量输入数据分配给所述组中的一个以产生分组数据; 和（d）适于输出分组数据的输出模块。

28. 发明申请

WO2006103665A2 ELECTROMAGNETIC SENSORS FOR TISSUE CHARACTERIZATION 审中-公开
标题翻译：用于组织特征的电磁传感器
公开(公告)号：WO2006103665A2
公开(公告)日：2006-10-05
申请号：PCT/IL2006/000392
申请日：2006-03-29
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B6/00
CPC分类号： A61B5/05 , G01R27/2664
摘要： A sensor for tissue characterization is provided, comprising: a resonator, configured to be placed proximally to an edge of a tissue for characterization, without penetrating the tissue, the resonator comprising a conductive structure associated with a diameter-equivalent dimension D, in a plane substantially parallel with the edge, and with a feature size d; and at least one conductive lead, for providing communication with an external system, wherein the resonator is configured to resonate at a frequency which corresponds to a free-air wavelength range of between about lambda and about 40lambda, wherein lambda is at least about ten times the diameter-equivalent D, and wherein upon receiving a signal in the range of between about lambda and about 40lambda, the sensor is configured to induce electric and magnetic fields, in a near zone, in the tissue, the near zone having a diameter of about D, so that the tissue in the near zone effectively functions as part of the resonator, influencing its resonating values, and so the tissue in the near zone is thereby characterized by its electromagnetic properties, by the resonating response of the resonator.
摘要翻译：提供了一种用于组织表征的传感器，包括：谐振器，被配置为被放置在组织的边缘的近侧，用于表征，而不穿透组织，所述谐振器包括与直径等效尺寸D相关联的导电结构基本上与边缘平行，具有特征尺寸d; 以及用于提供与外部系统的通信的至少一个导电引线，其中所述谐振器被配置为以对应于约λ和约40λ之间的自由空气波长范围的频率谐振，其中λ为至少约十倍直径等效D，并且其中当接收到在约λ和约λλ之间的范围内的信号时，所述传感器被配置为在所述组织中的近区域中诱导电场和磁场，所述近区域的直径为关于D，使得近区域中的组织有效地用作谐振器的一部分，影响其谐振值，因此通过谐振器的谐振响应，近区域中的组织的特征在于其电磁特性。

29. 发明申请

WO2006092797A3 DEVICE AND METHOD FOR TRANSPORTING AND HANDLING TISSUE 审中-公开
公开(公告)号：WO2006092797A3
公开(公告)日：2006-09-08
申请号：PCT/IL2006/000288
申请日：2006-03-02
申请人： DUNE MEDICAL DEVICES LTD. , HASHIMSHONY, Dan , YARDEN, Orit , AHARONOWITZ, Gal , COHEN, Gil , GELTNER, Iddo
发明人： HASHIMSHONY, Dan , YARDEN, Orit , AHARONOWITZ, Gal , COHEN, Gil , GELTNER, Iddo
IPC分类号： A61B19/00
摘要： A device and method are provided for tissue handling, while maintaining the in-vivo tissue orientation. The device includes a structure, configured for receiving and holding a tissue specimen, wherein the tissue specimen includes tissue positional references; and device positional references, associated with the structure, for fixing the orientation of the tissue specimen, when held by the device, so as to reflect the tissue specimen positional references.

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