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21. 发明申请

WO2007127273A3 METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION 审中-公开
标题翻译：改善细胞功能的方法和组合物
公开(公告)号：WO2007127273A3
公开(公告)日：2008-11-20
申请号：PCT/US2007010077
申请日：2007-04-24
申请人： ALLTECH INC , LYONS THOMAS P , POWER RONAN
发明人： LYONS THOMAS P , POWER RONAN
IPC分类号： A61K33/04 , A01N63/04
CPC分类号： A61K33/04
摘要： The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL- PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium).
摘要翻译：本发明涉及用于改变细胞功能的组合物和方法。特别地，本发明提供包含硒（例如SEL-PLEX）的组合物及其使用方法（例如，作为治疗和/或预防性治疗）。另外，本发明证明当施用于受试者时，具体形式的硒（例如SEL-PLEX）具有改变（例如，降低）各种组织中的基因表达的能力（例如，与未施用的受试者的表达相比较）硒）。

22. 发明申请

WO2007127273A2 METHODS AND COMPOSITIONS FOR ALTERING CELL FUNCTION 审中-公开
标题翻译：改善细胞功能的方法和组合物
公开(公告)号：WO2007127273A2
公开(公告)日：2007-11-08
申请号：PCT/US2007/010077
申请日：2007-04-24
申请人： ALLTECH, INC. , LYONS, Thomas, P. , POWER, Ronan
发明人： LYONS, Thomas, P. , POWER, Ronan
IPC分类号： A61K31/366
CPC分类号： A61K33/04
摘要： The present invention relates to compositions and methods for altering cell function. In particular, the present invention provides compositions comprising selenium (e.g., SEL- PLEX) and methods of using the same (e.g., as a therapeutic and/or prophylactic treatment). Additionally, the present invention demonstrates that specific forms of selenium (e.g., SEL-PLEX), when administered to a subject, possess the ability to alter (e.g., reduce) gene expression in various tissues (e.g., compared to expression in subjects not administered selenium).
摘要翻译：本发明涉及用于改变细胞功能的组合物和方法。特别地，本发明提供包含硒（例如SEL-PLEX）的组合物及其使用方法（例如，作为治疗和/或预防性治疗）。另外，本发明证明当施用于受试者时，具体形式的硒（例如SEL-PLEX）具有改变（例如，降低）各种组织中的基因表达的能力（例如，与未施用的受试者的表达相比较）硒）。

23. 发明申请

WO2004103086A2 METHODS FOR IMPROVING THE NUTRITIONAL QUALITY OF RESIDUES OF THE FUEL, BEVERAGE ALCOHOL, FOOD AND FEED INDUSTRIES 审中-公开
标题翻译：饮料，饮料，食品和饲料行业残留营养质量的改进方法
公开(公告)号：WO2004103086A2
公开(公告)日：2004-12-02
申请号：PCT/US2004/014735
申请日：2004-05-12
申请人： ALLTECH, INC. , POWER, Ronan, F.
发明人： POWER, Ronan, F.
IPC分类号： A23J
CPC分类号： C12F3/10 , A23J1/005 , A23K10/12 , A23K10/38 , A23K20/189 , A23K50/10 , A23K50/30 , C12F3/08 , Y02P60/873
摘要： A method is provided for improving the nutritional quality of a fibrous by-product or residue of a food manufacturing process, wherein the fibrous by-product or residue is inoculated with at least one filamentous fungus, and the fibrous by-product or residue is fermented thereby to decrease dry matter content, increase protein content, and decrease fat content of the by-product or residue. Suitable byproducts or residues include spent brewer’s grains, dried distiller’s grains, dried distiller’s solubles, distiller’s dried grains with solubles, residues of the cereal processing industry, wheat bran, soybean hulls, citrus pulp, beet pulp, rice husks or hulls, bagasse, apple pommace, and combinations thereof. Enzymes produced during the fermentation may also be used as valuable coproducts such as animal feed supplements, or may be used in primary fermentations for the brewing and distilling industry.
摘要翻译：提供了一种用于改善食品制造方法的纤维副产物或残余物的营养质量的方法，其中纤维副产物或残余物用至少一种丝状真菌接种，并且纤维副产物或残余物被发酵从而降低副产物或残留物的干物质含量，增加蛋白质含量和降低脂肪含量。合适的副产物或残留物包括废啤酒谷物，干蒸馏谷物，干蒸馏器的可溶物，具有可溶物的蒸馏干燥谷物，谷物加工业的残留物，麦麸，大豆皮，柑橘浆，甜菜浆，稻壳或壳，甘蔗渣，苹果 pommace及其组合。在发酵期间产生的酶也可以用作有价值的副产物，例如动物饲料添加剂，或者可用于酿造和蒸馏工业的初级发酵。

24. 发明申请

WO2022261086A1 IODOFORM COMPOSITIONS AND METHODS THEREOF 审中-公开
公开(公告)号：WO2022261086A1
公开(公告)日：2022-12-15
申请号：PCT/US2022/032491
申请日：2022-06-07
申请人： ALLTECH, INC.
发明人： HOLDER, Vaughn
IPC分类号： A61K31/02 , A23K20/105 , A23K50/10
摘要： The present disclosure provides composition comprising i) an animal feed composition and ii) iodoform. In addition, methods of reducing methane production in a rumen of a ruminant animal by administering the compositions are provided. The compositions and methods are configured so that rumen fermentation in the ruminant animal is not substantially affected and/or to increase propionate production in the rumen of the ruminant animal.

25. 发明申请

WO2017048253A1 COMPOSITIONS OF SELENOORGANIC COMPOUNDS AND METHODS OF USE THEREOF 审中-公开
标题翻译：有机化合物的组合物及其使用方法
公开(公告)号：WO2017048253A1
公开(公告)日：2017-03-23
申请号：PCT/US2015/050490
申请日：2015-09-16
申请人： ALLTECH, INC.
发明人： POWER, Ronan , LAN, Zi-Jian
IPC分类号： A01N55/02
CPC分类号： A61K31/7135 , A61K31/28 , A61K31/706 , A61K31/7064 , A61K31/7076 , A61K38/05 , A61K38/28 , C07D473/34
摘要： The present application relates to compositions comprising selenium compounds, such as 5'-Methylselenoadenosine, a compound of Formula (I), and combinations thereof, and methods of using the same for inhibiting β amyloid aggregation, ApoE4 expression, p38 or Tau protein phosphorylation, or increasing Neprilysin and Insulin Degrading Enzyme expression.
摘要翻译：本申请涉及包含硒化合物如5'-甲基硒腺嘌呤，式（I）化合物及其组合的组合物及其用于抑制β-淀粉样蛋白聚集，ApoE4表达，p38或Tau蛋白磷酸化的方法，或增加Neprilysin和胰岛素降解酶表达。

26. 发明申请

WO2015094390A1 SYSTEMS AND METHODS FOR ADJUSTING ANIMAL FEED 审中-公开
标题翻译：调整动物饲料的系统和方法
公开(公告)号：WO2015094390A1
公开(公告)日：2015-06-25
申请号：PCT/US2014/015736
申请日：2014-02-11
申请人： ALLTECH, INC. , MCKINNEY, Kyle , LOVELL, Allyson , HENRY, Benjamin , BECKER, Patrick , TIMMONS, Rebecca, A.
发明人： MCKINNEY, Kyle , LOVELL, Allyson , HENRY, Benjamin , BECKER, Patrick , TIMMONS, Rebecca, A.
IPC分类号： A23K1/00
CPC分类号： A23K1/001 , A23K10/14 , A23K50/30 , A23K50/75
摘要： The present application provides systems and methods for analyzing animal feeds and for adjusting animal feeds to improve the digestibility of animal feed components. Digestibility of animal feed can be determined by performing in vitro digestion of the feed and analyzing concentrations of residual components in the digested feed by NIR spectroscopy. Animal feed compositions can be adjusted to improve digestibility of components in the feed. The systems and methods of the present application can be used to determine the effect of an additive on the digestibility of feed.
摘要翻译：本申请提供了用于分析动物饲料和调整动物饲料以提高动物饲料组分的消化率的系统和方法。动物饲料的消化率可以通过进行饲料的体外消化和通过NIR光谱分析消化的饲料中残留组分的浓度来测定。可以调节动物饲料组合物以改善饲料中组分的消化率。本申请的系统和方法可用于确定添加剂对饲料消化率的影响。

27. 发明申请

WO2010083336A3 CLAY INTERLACED YEAST COMPOSITIONS AND METHODS OF UTILIZING THE SAME 审中-公开
标题翻译：粘土界面组合物及其利用方法
公开(公告)号：WO2010083336A3
公开(公告)日：2012-06-07
申请号：PCT/US2010021076
申请日：2010-01-14
申请人： ALLTECH INC , YIANNIKOURIS ALEXANDROS , THIELEN URSULA ANNE
发明人： YIANNIKOURIS ALEXANDROS , THIELEN URSULA ANNE
IPC分类号： C12N1/16
CPC分类号： C12N1/16 , A23K10/16 , A23K10/18 , A23K20/28 , A23K50/75 , A23L2/52 , A23L33/14 , A61K36/06 , C12H1/0408 , C12H1/0424
摘要： The present invention relates to compositions comprising yeast cells and/or yeast cell components and methods for producing and utilizing the same. In particular, the invention provides novel yeast comprising altered cell wall structure (e.g., clay and/or clay component(s) integrated (e.g., interlaced) into cell wall(s) and/or cell wall(s) comprising altered glucan:mannan ratio), methods of producing the same, compositions comprising and/or derived from the same, and methods of using the same (e.g., to sequester and/or adsorb bacteria and toxins). Compositions and methods of the invention find use in a variety of applications including dietary (e.g., admixing with feedstuffs or otherwise feeding to animals), therapeutic, prophylactic (e.g. admixing with bedding sources and/or other materials that come into contact with animals, usage during food and beverage processing and manufacture, and usage during filtration of liquids) as well as research applications.
摘要翻译：本发明涉及包含酵母细胞和/或酵母细胞成分的组合物及其生产和利用方法。特别地，本发明提供了包含改变的细胞壁结构（例如，粘土和/或粘土组分（例如，交织）到细胞壁和/或细胞壁中的新型酵母，其包含改变的葡聚糖：甘露聚糖比例），其制备方法，包含和/或衍生自其的组合物及其使用方法（例如，螯合和/或吸附细菌和毒素）。本发明的组合物和方法可用于各种应用，包括饮食（例如，与饲料混合或以其他方式喂养动物），治疗，预防（例如与床上用品和/或与动物接触的其它材料混合，使用在食品和饮料加工和制造过程中以及在液体过滤期间的使用）以及研究应用。

28. 发明申请

WO2011031562A1 SYNTHETIC MYCOTOXIN ADSORBENTS AND METHODS OF MAKING AND UTILIZING THE SAME 审中-公开
标题翻译：合成MYCOTOXIN吸附剂及其制备和利用方法
公开(公告)号：WO2011031562A1
公开(公告)日：2011-03-17
申请号：PCT/US2010/047032
申请日：2010-08-27
申请人： ALLTECH, INC. , YIANNIKOURIS, Alexandros , KWIATKOWSKI, Stefan , KUDUPOJE, Manoj, Bojappa , MATNEY, Clayton
发明人： YIANNIKOURIS, Alexandros , KWIATKOWSKI, Stefan , KUDUPOJE, Manoj, Bojappa , MATNEY, Clayton
IPC分类号： G01N33/00
CPC分类号： C07C231/02 , A23L5/273 , B01D15/3852 , B01J20/26 , B01J20/268 , C07C217/84 , C07C235/60 , C07D209/38 , C08F220/28 , C08F222/1006 , C08F226/06 , C12H1/0424 , Y10T436/255
摘要： The present invention relates generally to molecularly imprinted polymers (MIPs). In particular, the present invention relates to reusable, ecologically friendly MIPs that can be produced in relatively large quantities, methods of producing the same, and methods of utilizing the same (e.g., to sequester and/or adsorb target compounds (e.g., mycotoxins)). Compositions and methods of the invention find use in a variety of applications including dietary therapeutic, prophylactic, food and beverage processing and manufacture, as well as research, quality control and traceability applications.
摘要翻译：本发明一般涉及分子印迹聚合物（MIP）。特别地，本发明涉及可以相对大量生产的可重复使用的，生态友好的MIP，其生产方法及其利用方法（例如，螯合和/或吸附目标化合物（例如霉菌毒素））。本发明的组合物和方法可用于各种应用，包括饮食治疗，预防，食品和饮料加工和制造，以及研究，质量控制和可追溯性应用。

29. 发明申请

WO2010083336A2 CLAY INTERLACED YEAST COMPOSITIONS AND METHODS OF UTILIZING THE SAME 审中-公开
标题翻译：粘土界面组合物及其利用方法
公开(公告)号：WO2010083336A2
公开(公告)日：2010-07-22
申请号：PCT/US2010/021076
申请日：2010-01-14
申请人： ALLTECH, INC. , YIANNIKOURIS, Alexandros , THIELEN, Ursula Anne
发明人： YIANNIKOURIS, Alexandros , THIELEN, Ursula Anne
IPC分类号： A61K36/06 , C12N1/16 , A23L1/28 , A23K1/00 , A23L2/38 , C12G1/00 , C12C1/00
CPC分类号： C12N1/16 , A23K10/16 , A23K10/18 , A23K20/28 , A23K50/75 , A23L2/52 , A23L33/14 , A61K36/06 , C12H1/0408 , C12H1/0424
摘要： The present invention relates to compositions comprising yeast cells and/or yeast cell components and methods for producing and utilizing the same. In particular, the invention provides novel yeast comprising altered cell wall structure (e.g., clay and/or clay component(s) integrated (e.g., interlaced) into cell wall(s) and/or cell wall(s) comprising altered glucan:mannan ratio), methods of producing the same, compositions comprising and/or derived from the same, and methods of using the same (e.g., to sequester and/or adsorb bacteria and toxins). Compositions and methods of the invention find use in a variety of applications including dietary (e.g., admixing with feedstuffs or otherwise feeding to animals), therapeutic, prophylactic (e.g. admixing with bedding sources and/or other materials that come into contact with animals, usage during food and beverage processing and manufacture, and usage during filtration of liquids) as well as research applications.
摘要翻译：本发明涉及包含酵母细胞和/或酵母细胞成分的组合物及其生产和利用方法。特别地，本发明提供了包含改变的细胞壁结构（例如，粘土和/或粘土组分（例如，交织）到细胞壁和/或细胞壁中的新型酵母，其包含改变的葡聚糖：甘露聚糖比例），其制备方法，包含和/或衍生自其的组合物及其使用方法（例如，螯合和/或吸附细菌和毒素）。本发明的组合物和方法可用于各种应用，包括饮食（例如，与饲料混合或以其他方式喂养动物），治疗，预防（例如与床上用品和/或与动物接触的其它材料混合，使用在食品和饮料加工和制造过程中以及在液体过滤期间的使用）以及研究应用。

30. 发明申请

WO2008144543A2 COMPOSITIONS AND METHODS FOR ESTABLISHING AND/OR MAINTAINING PREGNANCY 审中-公开
标题翻译：用于建立和/或维护孕妇的组合物和方法
公开(公告)号：WO2008144543A2
公开(公告)日：2008-11-27
申请号：PCT/US2008/063944
申请日：2008-05-16
申请人： ALLTECH, INC. , LYONS, Thomas P. , POWER, Ronan
发明人： LYONS, Thomas P. , POWER, Ronan
IPC分类号： A61K33/04 , A61K31/19 , A61K38/00
CPC分类号： A61K36/064 , A61K33/04 , A61K36/06 , A61K48/00

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