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11. 发明申请

WO2017180985A1 ACCURATE HEART RATE MEASUREMENT BY RADAR USING ADAPTIVE HARMONICS FILTER 审中-公开
标题翻译：雷达使用自适应谐波滤波器进行准确的心率测量
公开(公告)号：WO2017180985A1
公开(公告)日：2017-10-19
申请号：PCT/US2017/027597
申请日：2017-04-14
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.
发明人： HAYWARD, Linda, Frances , LIN, Jenshan , HUANG, Tien-yu
IPC分类号： A61B5/11 , A61B5/02 , A61B5/024 , G01S13/88
CPC分类号： A61B5/725 , A61B5/0205 , A61B5/024 , A61B5/0816 , A61B5/1135 , A61B5/4839 , A61B5/7246 , G01S7/415 , G01S13/536 , G01S13/88
摘要： Various examples are provided for accurate heart rate measurement. In one example, a method includes determining a respiratory rate (RR) and respiration displacement from radar-measured cardiorespiratory motion data; adjusting notch depths of a harmonics comb notch digital filter (HCNDF) based upon the respiration displacement; generating filtered cardiorespiratory data by filtering the radar-measured cardiorespiratory motion data with the HCNDF; and identifying a heart rate (HR) from the filtered cardiorespiratory data. In another example, a system includes radar circuitry configured to receive a cardiorespiratory motion signal reflected from a monitored subject; and signal processing circuitry configured to determine a respiration displacement based upon the cardiorespiratory motion signal; adjust notch depths of a HCNDF based upon the respiration displacement; filter the cardiorespiratory motion data with the HCNDF; and identifying a heart rate (HR) from the filtered cardiorespiratory data.
摘要翻译：为准确的心率测量提供了各种示例。在一个示例中，一种方法包括确定来自雷达测量的心肺运动数据的呼吸速率（RR）和呼吸位移; 基于呼吸位移来调整谐波梳齿陷波数字滤波器（HCNDF）的陷波深度; 通过用HCNDF过滤雷达测量的心肺运动数据来生成经过滤的心肺呼吸数据; 并从过滤的心肺数据中识别心率（HR）。在另一个例子中，一种系统包括配置成接收从监测对象反射的心肺呼吸运动信号的雷达电路; 以及信号处理电路，配置成基于所述心肺运动信号确定呼吸位移; 基于呼吸位移来调整HCNDF的切口深度; 用HCNDF过滤心肺运动数据; 并从过滤后的心肺数据中识别心率（HR）。

12. 发明申请

WO2017145119A1 ESTIMATION OF GLUCOSE RATE OF APPEARANCE FROM CGS AND SUBCUTANEOUS INSULIN DELIVERY IN TYPE 1 DIABETES 审中-公开
标题翻译： 1型糖尿病患者CGS和皮下注射胰岛素释放的葡萄糖率评估
公开(公告)号：WO2017145119A1
公开(公告)日：2017-08-31
申请号：PCT/IB2017/051100
申请日：2017-02-24
申请人： KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY , PRINCE SULTAN UNIVERSITY
发明人： LALEG, Taous Meriem , AL-MATOUQ, Ali Ahmed
IPC分类号： A61B5/00 , A61B5/145 , G06F19/00
CPC分类号： A61B5/4839 , A61B5/14532 , A61B5/7278 , A61M5/00 , A61M5/14244 , A61M2205/3303 , A61M2205/3523 , A61M2205/50 , A61M2205/52 , A61M2230/005 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H50/50
摘要： Method and System for providing estimates of Glucose Rate of Appearance from the intestine (GRA) using continuous glucose sensor measurements (CGS) taken from the subcutaneous of a diabetes patient and the amount of insulin administered to the patient.
摘要翻译：用于使用从糖尿病患者的皮下采集的连续葡萄糖传感器测量值（CGS）和施用给患者的胰岛素的量来提供来自肠的葡萄糖出现率（GRA）的估计的方法和系统

13. 发明申请

WO2017143200A1 DRUG DELIVERY INTEGRATED CIRCUIT (IC) AND SYSTEM 审中-公开
标题翻译：药物递送集成电路（IC）和系统
公开(公告)号：WO2017143200A1
公开(公告)日：2017-08-24
申请号：PCT/US2017/018386
申请日：2017-02-17
申请人： UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
发明人： HUR, Byul , HARDY, John , EISENSTADT, William, R. , SCHMIDT, Christine, E.
IPC分类号： A61K9/00 , A61K47/30 , A61K9/70
CPC分类号： A61K9/0097 , A61B5/0008 , A61B5/0022 , A61B5/0031 , A61B5/01 , A61B5/14532 , A61B5/4839 , A61B5/746 , A61B2505/07 , A61B2560/0209 , A61B2562/043 , A61M31/002 , G06F19/00 , G16H40/67
摘要： Wireless and non-wireless drug delivery integrated circuits, systems, and methods of delivering therapeutic pharmaceutical compounds are provided. The system can include a control module, a wireless drug delivery integrated circuit, a first electrode and a second electrode that are both attached to the wireless drug delivery integrated circuit, an electroactive polymer, and a pharmaceutical compound. The electroactive polymer and the pharmaceutical compound can be formed as films on one of the electrodes and, when placed in a solution, a voltage potential can be applied across the electrodes causing the pharmaceutical compound to be released into the solution.
摘要翻译：提供了无线和非无线药物输送集成电路，系统和输送治疗药物化合物的方法。该系统可以包括控制模块，无线药物输送集成电路，都连接到无线药物输送集成电路的第一电极和第二电极，电活性聚合物和药物化合物。电活性聚合物和药物化合物可以形成为一个电极上的薄膜，并且当置于溶液中时，可以在电极上施加电压电势，使药物化合物释放到溶液中。

14. 发明申请

WO2017120615A3 SYSTEM AND METHOD FOR HEALTH MONITORING INCLUDING A USER DEVICE AND BIOSENSOR 审中-公开
标题翻译：用于健康监测的系统和方法，包括用户设备和生物传感器
公开(公告)号：WO2017120615A3
公开(公告)日：2017-08-10
申请号：PCT/US2017012889
申请日：2017-01-10
申请人： SANMINA CORP
发明人： NEWBERRY ROBERT STEVEN
IPC分类号： A61B5/145 , A61B5/00 , A61B5/024 , A61B5/1455
CPC分类号： A61B5/0022 , A61B5/0002 , A61B5/0008 , A61B5/02416 , A61B5/1118 , A61B5/14532 , A61B5/1455 , A61B5/14551 , A61B5/4839 , A61B5/6817 , A61B5/6826 , A61B5/743 , A61B2560/0223
摘要： User equipment is configured to collect biosensor data from an integrated biosensor or by receiving biosensor data from one or more external biosensors. The user equipment includes a Health Monitoring (HM) application. The HM application is configured to receive the biosensor data and display the biosensor data on the display of the user equipment. The user equipment may also communicate biosensor data over a local or wide area network to a third party, such as a pharmacy or health care provider.
摘要翻译：用户设备被配置为从集成的生物传感器收集生物传感器数据或通过从一个或多个外部生物传感器接收生物传感器数据。用户设备包括健康监测（HM）应用。 HM应用被配置为接收生物传感器数据并在用户设备的显示器上显示生物传感器数据。用户设备还可以通过局域网或广域网将生物传感器数据传送给第三方，诸如药房或健康护理提供者。

15. 发明申请

WO2017116503A1 METHODS FOR CONTINUOUS GLUCOSE MONITORING 审中-公开
标题翻译：连续葡萄糖监测的方法
公开(公告)号：WO2017116503A1
公开(公告)日：2017-07-06
申请号：PCT/US2016/043512
申请日：2016-07-22
申请人： MEDTRONIC MINIMED, INC.
发明人： NOGUEIRA, Keith , ENGEL, Taly G. , LI, Xiaolong , LIANG, Bradley C. , SHAH, Rajiv , LIU, Mike C. , TSAI, Andy Y. , KIM, Jaeho , VARSAVSKY, Andrea , YU, Fei , GAUTHAM, Raghavendhar , NISHIDA, Jeffrey
IPC分类号： A61B5/145 , A61B5/1486 , A61B5/1495 , A61B5/053
CPC分类号： A61B5/14865 , A61B5/0538 , A61B5/14532 , A61B5/1495 , A61B5/4839 , A61B5/7221
摘要： Electrochemical impedance spectroscopy (EIS) may be used in conjunction with continuous glucose monitoring (CGM) to enable identification of valid and reliable sensor data, as well implementation of Smart Calibration algorithms. Calibration of a glucose sensor may also be performed using a calibration factor based on the age of the sensor. Finally, a calibration interval for a glucose sensor may be determined.
摘要翻译：电化学阻抗谱（EIS）可以与连续血糖监测（CGM）结合使用，以便识别有效和可靠的传感器数据，以及实施智能校准算法。葡萄糖传感器的校准也可以使用基于传感器的年龄的校准因子来执行。最后，可以确定葡萄糖传感器的校准间隔。

16. 发明申请

WO2017091502A1 GARMENTS FOR WEARABLE MEDICAL DEVICES 审中-公开
标题翻译：可穿戴医疗设备的服装
公开(公告)号：WO2017091502A1
公开(公告)日：2017-06-01
申请号：PCT/US2016/063078
申请日：2016-11-21
申请人： ZOLL MEDICAL CORPORATION
发明人： KAIB, Thomas, E. , VOLPE, Shane, S. , FRANK, Gregory, R. , FREEMAN, Gary, A. , OWENS, Mark, Jerome
IPC分类号： A61N1/39 , A61N1/04
CPC分类号： A61N1/36585 , A41D13/1281 , A41D2400/20 , A41D2400/60 , A61B5/021 , A61B5/04085 , A61B5/0452 , A61B5/0537 , A61B5/0816 , A61B5/1118 , A61B5/14542 , A61B5/4839 , A61B5/6805 , A61B7/00 , A61B7/003 , A61N1/0456 , A61N1/046 , A61N1/0476 , A61N1/0484 , A61N1/3625 , A61N1/3925 , A61N1/3968 , A61N1/3987
摘要： According to at least one aspect, a wearable cardiac device is provided. The wearable cardiac device includes a garment worn about a torso of a patient, at least one sensing electrode to monitor cardiac activity of the patient, and a controller including a plurality of separate and distinct modules distributed about and/or integrated into the garment. The plurality of separate and distinct modules includes, for example, an operations module coupled to the at least one sensing electrode and configured to detect at least one cardiac condition of the patient and/or a communications module coupled to the operations module to communicate with an external device. In some examples, the wearable cardiac device may be configured as a treatment device and include an energy storage module coupled to at least one therapy electrode and configured to store energy for at least one therapeutic shock to be applied to the patient.
摘要翻译：根据至少一个方面，提供了一种可穿戴式心脏装置。可穿戴式心脏装置包括围绕患者躯干穿着的衣服，监测患者心脏活动的至少一个感测电极以及包括分布在和/或集成到衣服中的多个分离且不同的模块的控制器。多个独立且不同的模块包括例如耦合到至少一个感测电极并且被配置为检测患者和/或耦合到操作模块的通信模块的至少一个心脏状况以与外部设备。在一些示例中，可穿戴心脏装置可以被配置为治疗装置并且包括能量存储模块，该能量存储模块被耦合到至少一个治疗电极并且被配置为存储用于施加到患者的至少一个治疗电击的能量。

17. 发明申请

WO2017060887A1 FIBER OPTIC LIGHT DELIVERY, MONITORING AND APPARATUS THEREFORE 审中-公开
标题翻译：光纤光输送，监测和装置
公开(公告)号：WO2017060887A1
公开(公告)日：2017-04-13
申请号：PCT/IB2016/056061
申请日：2016-10-10
申请人： THERALASE TECHNOLOGIES, INC , UNIVERSITY HEALTH NETWORK
发明人： LIGLE, Lothar , MANDEL, Arkady , EMBREE, Wayne , ZHANG, Kai , LEM, Don , WU, Jenny , DUMOULIN-WHITE, Roger
IPC分类号： A61N5/06 , A61B1/07 , A61B1/307 , G02B6/42
CPC分类号： A61N5/062 , A61B5/0084 , A61B5/202 , A61B5/4839 , A61B5/6858 , A61B2090/306 , A61M25/0074 , A61M2205/3306 , A61M2210/1085 , A61N2005/061 , A61N2005/063
摘要： Apparatus for illuminating comprises one or more fibers, the one or more fibers including fiber portions meeting at an apex and a bottom location to form a three dimensional cage; a detector attached to each of the fiber portions for receiving light and transmitting light along each of the fiber portions, respectively; and an illumination member situated within the cage. A method for illuminating a hollow member includes the steps of inserting one or more fibers into the hollow member, wherein one or more fibers include fiber portions that meet at a location to form a three-dimensional cage; permitting light to emit from within the three-dimensional cage and towards the fiber portions; receiving light at distinct locations on each of said fibers; and allowing each of the fibers to transmit the light received on each of the fiber portions out of the hollow member.
摘要翻译：用于照明的装置包括一个或多个纤维，所述一个或多个纤维包括在顶点与底部位置相交的纤维部分，以形成三维笼; 检测器，分别连接到每个光纤部分，用于接收光并沿着每个光纤部分透射光; 以及位于所述笼内的照明构件。照明中空构件的方法包括将一根或多根纤维插入中空构件的步骤，其中一根或多根纤维包括在形成三维笼的位置相遇的纤维部分; 允许光从三维笼内向纤维部分发射; 在每个所述纤维上的不同位置处接收光; 并且允许每个光纤将接收在每个光纤部分上的光透射出中空部件。

18. 发明申请

WO2017059530A1 METHOD FOR DELIVERY OF BREATHING GAS TO A PATIENT AND SYSTEM FOR PERFORMING SAME 审中-公开
标题翻译：将呼吸气体输送给患者和执行其的系统的方法
公开(公告)号：WO2017059530A1
公开(公告)日：2017-04-13
申请号：PCT/CA2016/051153
申请日：2016-10-04
申请人： UNIVERSITÉ LAVAL , UNIVERSITÉ DE BRETAGNE OCCIDENTALE , OXY'NOV INC.
发明人： LELLOUCHE, Francois , L'HER, Erwan , GOSSELIN, Benoit , NGUYEN, Quang-thang
IPC分类号： A61M16/10 , A61B5/087 , A61B5/1455 , A61M16/12
CPC分类号： A61B5/14551 , A61B5/0816 , A61B5/4839 , A61M11/00 , A61M16/0051 , A61M16/0066 , A61M16/0069 , A61M16/026 , A61M16/1075 , A61M16/12 , A61M16/125 , A61M16/16 , A61M16/161 , A61M2016/0033 , A61M2202/0208 , A61M2205/3334 , A61M2205/3368 , A61M2205/3375 , A61M2230/06 , A61M2230/205 , A61M2230/42 , A61M2230/432 , A61M2230/60 , A61M2230/005
摘要： A method for controlling the delivery of a breathing gas to a patient. The method comprises: delivering a flow of breathing gas to a patient, the breathing gas having a breathing gas flowrate and a fraction of inspired oxygen; measuring an oxygen saturation level of the patient; determining a respiratory rate of the patient; automatically adjusting the fraction of inspired oxygen of the breathing gas based on the measured oxygen saturation level of the patient and a breathing gas flowrate set-point; and automatically adjusting the breathing gas flowrate set-point based on the determined respiratory rate of the patient.
摘要翻译：一种用于控制向患者输送呼吸气体的方法。该方法包括：向患者输送呼吸气体流，所述呼吸气体具有呼吸气体流量和一部分吸入氧气; 测量患者的氧饱和度水平; 确定患者的呼吸频率; 基于测量的患者的氧饱和度水平和呼吸气体流量设定点自动调节呼吸气体的吸入氧气的分数; 并且基于确定的患者呼吸速率自动调节呼吸气体流量设定点。

19. 发明申请

WO2017055450A1 INTRACRANIAL PRESSURE ADJUSTMENT INFUSION SYSTEM AND METHOD 审中-公开
标题翻译：血压调节灌注系统及方法
公开(公告)号：WO2017055450A1
公开(公告)日：2017-04-06
申请号：PCT/EP2016/073256
申请日：2016-09-29
申请人： SEIRATHERM GMBH
发明人： ROTH, Matthias , REICHTHALHAMMER, Thomas
IPC分类号： A61B5/03 , A61B5/00 , A61F7/12 , A61B5/01 , A61B5/021 , A61B5/11 , A61M5/44 , A61F7/00 , A61M27/00
CPC分类号： A61B5/031 , A61B5/01 , A61B5/021 , A61B5/11 , A61B5/4836 , A61B5/4839 , A61F7/0085 , A61F2007/0002 , A61F2007/0059 , A61F2007/126 , A61M5/142 , A61M5/1723 , A61M5/44 , A61M27/006
摘要： An adjustment device for controlling infusion fluid, in particular for temperature regulation therapy such as hypothermia treatment is adapted for intracranial hypertension (ICH) control. The device comprises a control unit configured to receive input signals indicating intracranial pressure (ICP) and to provide output signals indicating one or more recommendations for therapy based on said received input signals.
摘要翻译：用于控制输液的调节装置，特别是用于诸如低温治疗的温度调节治疗适用于颅内高压（ICH）控制。该装置包括控制单元，其被配置为接收指示颅内压（ICP）的输入信号，并且基于所述接收到的输入信号提供指示用于治疗的一个或多个推荐的输出信号。

20. 发明申请

WO2017054006A1 SYSTEM AND METHOD FOR A DRUG DELIVERY AND BIOSENSOR PATCH 审中-公开
标题翻译：用于药物递送和生物传感器贴片的系统和方法
公开(公告)号：WO2017054006A1
公开(公告)日：2017-03-30
申请号：PCT/US2016/053845
申请日：2016-09-26
申请人： SANMINA CORPORATION
发明人： NEWBERRY, Robert, Steven , RODENCAL, Matthew
IPC分类号： A61B5/06 , A61B5/00
CPC分类号： A61B5/02438 , A61B5/02055 , A61B5/021 , A61B5/02416 , A61B5/0261 , A61B5/0816 , A61B5/1455 , A61B5/4839 , A61B5/4848 , A61B5/681 , A61B5/6817 , A61B5/6833 , A61B5/7235
摘要： An integrated drug delivery and biosensor (IDDB) system is implemented on a patch or arm band. The drug delivery system includes needles adapted to pierce the skin and direct injection of a predetermined dosage of medication through the needles into the epidermis of the skin of a patient. The integrated biosensor monitors absorption of the medication into the epidermis of the skin of the patient and may also monitor concentration of the medication or other relevant substances in arterial blood flow of the patient. The integrated biosensor may also monitor a patient's vitals in response to the medication. The integrated biosensor may then alter dosage or frequency of administration of dosages or even halt a dosage of medication in response to the patient's vitals or absorption of the medication.
摘要翻译：在贴片或手臂带上实施综合药物递送和生物传感器（IDDB）系统。药物递送系统包括适于刺穿皮肤并且将预定剂量的药物通过针直接注射到患者皮肤的表皮中的针。集成的生物传感器监测药物对患者皮肤的表皮的吸收，还可以监测患者动脉血流中药物或其他相关物质的浓度。集成的生物传感器还可以响应于药物监测患者的生命体征。然后，集成的生物传感器可以改变施用剂量的剂量或频率，或者甚至响应于患者的生命体征或药物的吸收而停止一定剂量的药物。

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